JP2013529086A5 - - Google Patents
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- Publication number
- JP2013529086A5 JP2013529086A5 JP2013511303A JP2013511303A JP2013529086A5 JP 2013529086 A5 JP2013529086 A5 JP 2013529086A5 JP 2013511303 A JP2013511303 A JP 2013511303A JP 2013511303 A JP2013511303 A JP 2013511303A JP 2013529086 A5 JP2013529086 A5 JP 2013529086A5
- Authority
- JP
- Japan
- Prior art keywords
- acid sequence
- progeny
- genetically modified
- nucleic acid
- brassica plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 241000219198 Brassica Species 0.000 claims description 113
- 150000007523 nucleic acids Chemical group 0.000 claims description 81
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 73
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 23
- 235000019198 oils Nutrition 0.000 claims description 23
- 102000005870 Coenzyme A Ligases Human genes 0.000 claims description 20
- 108010011449 Long-chain-fatty-acid-CoA ligase Proteins 0.000 claims description 20
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims description 20
- MBMBGCFOFBJSGT-KUBAVDMBSA-N docosahexaenoic acid Natural products CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims description 19
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims description 17
- 108010001814 phosphopantetheinyl transferase Proteins 0.000 claims description 17
- 238000000034 method Methods 0.000 claims description 15
- 235000021588 free fatty acids Nutrition 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 10
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims description 9
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims description 8
- 239000013604 expression vector Substances 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 238000003259 recombinant expression Methods 0.000 claims description 8
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 6
- 229930195729 fatty acid Natural products 0.000 claims description 6
- 239000000194 fatty acid Substances 0.000 claims description 6
- 150000004665 fatty acids Chemical class 0.000 claims description 6
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 claims description 6
- 230000001131 transforming effect Effects 0.000 claims description 6
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 5
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims description 4
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims description 4
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims description 4
- 102000000452 Acetyl-CoA carboxylase Human genes 0.000 claims description 4
- 108010016219 Acetyl-CoA carboxylase Proteins 0.000 claims description 4
- 108010018763 Biotin carboxylase Proteins 0.000 claims description 4
- 102000002148 Diacylglycerol O-acyltransferase Human genes 0.000 claims description 4
- 108010001348 Diacylglycerol O-acyltransferase Proteins 0.000 claims description 4
- 101100280636 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) fae-1 gene Proteins 0.000 claims description 4
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000005642 Oleic acid Substances 0.000 claims description 4
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims description 4
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims description 4
- 229960004488 linolenic acid Drugs 0.000 claims description 4
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims description 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 3
- 235000013376 functional food Nutrition 0.000 claims description 3
- 108020004707 nucleic acids Proteins 0.000 claims description 3
- 102000039446 nucleic acids Human genes 0.000 claims description 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims description 3
- 229940127557 pharmaceutical product Drugs 0.000 claims description 3
- 244000178993 Brassica juncea Species 0.000 claims description 2
- 235000011332 Brassica juncea Nutrition 0.000 claims description 2
- 235000014700 Brassica juncea var napiformis Nutrition 0.000 claims description 2
- 240000002791 Brassica napus Species 0.000 claims description 2
- 235000011293 Brassica napus Nutrition 0.000 claims description 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims description 2
- 229940090949 docosahexaenoic acid Drugs 0.000 claims description 2
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims description 2
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims description 2
- 230000002068 genetic effect Effects 0.000 claims description 2
- 108090000992 Transferases Proteins 0.000 claims 1
- 102000004357 Transferases Human genes 0.000 claims 1
- 239000003921 oil Substances 0.000 description 13
- 241000196324 Embryophyta Species 0.000 description 6
- 235000011331 Brassica Nutrition 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34553710P | 2010-05-17 | 2010-05-17 | |
| US61/345,537 | 2010-05-17 | ||
| PCT/US2011/036869 WO2011146524A1 (en) | 2010-05-17 | 2011-05-17 | Production of dha and other lc-pufas in plants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013529086A JP2013529086A (ja) | 2013-07-18 |
| JP2013529086A5 true JP2013529086A5 (cg-RX-API-DMAC7.html) | 2014-07-03 |
| JP6059138B2 JP6059138B2 (ja) | 2017-01-11 |
Family
ID=44992026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013511303A Expired - Fee Related JP6059138B2 (ja) | 2010-05-17 | 2011-05-17 | 植物におけるｄｈａおよび他のｌｃ−ｐｕｆａの産生 |
Country Status (25)
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11236351B2 (en) * | 2010-05-17 | 2022-02-01 | Dow Agrosciences Llc | Production of DHA and other LC PUFAs in plants |
| TW201144442A (en) * | 2010-05-17 | 2011-12-16 | Dow Agrosciences Llc | Production of DHA and other LC-PUFAs in plants |
| MX2013005583A (es) * | 2010-12-30 | 2013-07-05 | Ericsson Telefon Ab L M | Metodos y aparatos para permitir indicacion de reduccion de potencia en reporte de margen de potencia en un sistema de telecomunicaciones. |
| TW201307553A (zh) * | 2011-07-26 | 2013-02-16 | Dow Agrosciences Llc | 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術 |
| US8951776B2 (en) | 2011-10-19 | 2015-02-10 | Massachusetts Institute Of Technology | Engineered microbes and methods for microbial oil production |
| KR20140116445A (ko) | 2011-12-30 | 2014-10-02 | 다우 아그로사이언시즈 엘엘씨 | 카놀라 가공 동안의 ｄｈａ 유지 |
| US8816111B2 (en) | 2012-06-15 | 2014-08-26 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising polyunsaturated fatty acids |
| AR091774A1 (es) * | 2012-07-16 | 2015-02-25 | Dow Agrosciences Llc | Proceso para el diseño de las secuencias de adn repetidas, largas, divergentes de codones optimizados |
| CN110876413A (zh) * | 2012-09-11 | 2020-03-13 | 美国陶氏益农公司 | 与dha共混的ω-9芸苔油 |
| AU2014227823A1 (en) | 2013-03-15 | 2015-09-03 | Lisa HOLLISTER | Genetically modified plants that are insect-resistant and/or rot-resistant |
| US20140283220A1 (en) * | 2013-03-15 | 2014-09-18 | Yi Li | Genetically Modified Plants that are Herbivore-Resistant |
| CN105793427A (zh) | 2013-10-04 | 2016-07-20 | 美国陶氏益农公司 | 玉米金属硫蛋白样调节元件及其用途 |
| BR102014025574A2 (pt) | 2013-10-15 | 2015-09-29 | Dow Agrosciences Llc | elementos regulatórios de zea mays e usos dos mesmos |
| BR102014025499A2 (pt) | 2013-10-15 | 2015-09-29 | Dow Agrosciences Llc | elementos regulatórios de zea mays e uso dos mesmos |
| BR102014029437A2 (pt) | 2013-11-26 | 2015-07-07 | Dow Agrosciences Llc | Produção de ácidos graxos ômega-3 polinsaturados de cadeia longa em culturas oleaginosas por uma pufa sintase de traustoquitrídio |
| WO2015196250A1 (en) | 2014-06-27 | 2015-12-30 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising docosapentaenoic acid |
| AU2014366839B2 (en) | 2013-12-18 | 2021-07-01 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising long chain polyunsaturated fatty acids |
| TW201527316A (zh) | 2013-12-31 | 2015-07-16 | Dow Agrosciences Llc | 新穎玉米泛素啓動子（五） |
| TW201527312A (zh) | 2013-12-31 | 2015-07-16 | Dow Agrosciences Llc | 新穎玉米泛素啓動子（一） |
| TW201527314A (zh) | 2013-12-31 | 2015-07-16 | Dow Agrosciences Llc | 新穎玉米泛素啓動子（三） |
| TW201527313A (zh) | 2013-12-31 | 2015-07-16 | Dow Agrosciences Llc | 新穎玉米泛素啓動子（二） |
| BR102015000943A2 (pt) | 2014-01-17 | 2016-06-07 | Dow Agrosciences Llc | expressão aumentada de proteína em planta |
| EP3099782B1 (en) | 2014-01-28 | 2019-03-20 | DSM IP Assets B.V. | Factors for the production and accumulation of polyunsaturated fatty acids (pufas) derived from pufa synthases |
| TW201538518A (zh) | 2014-02-28 | 2015-10-16 | Dow Agrosciences Llc | 藉由嵌合基因調控元件所賦予之根部特異性表現 |
| CN107532179B (zh) | 2014-11-14 | 2021-10-15 | 巴斯夫植物科学有限公司 | 产生pufa的材料和方法及含有pufa的组合物 |
| KR20170136549A (ko) | 2015-04-15 | 2017-12-11 | 다우 아그로사이언시즈 엘엘씨 | 트랜스젠 발현을 위한 식물 프로모터 |
| CN107624136A (zh) | 2015-04-15 | 2018-01-23 | 美国陶氏益农公司 | 用于转基因表达的植物启动子 |
| TW201718862A (zh) | 2015-09-22 | 2017-06-01 | Dow Agrosciences Llc | 用於轉殖基因表現之植物啟動子及３’ｕｔｒ |
| TW201718861A (zh) | 2015-09-22 | 2017-06-01 | 道禮責任有限公司 | 用於轉殖基因表現之植物啟動子及３’ｕｔｒ |
| EP3365451B1 (en) | 2015-10-22 | 2020-06-24 | Dow Agrosciences LLC | Plant promoter for transgene expression |
| US20170121726A1 (en) | 2015-11-04 | 2017-05-04 | Dow Agrosciences Llc | Plant promoter for transgene expression |
| JP6966040B2 (ja) | 2016-05-12 | 2021-11-10 | ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. | 微細藻類中でのオメガ−３多価不飽和脂肪酸産生を増加させる方法 |
| EP4338586A3 (en) * | 2016-06-16 | 2024-06-26 | Nuseed Nutritional Australia Pty Ltd | Elite event canola ns-b50027-4 |
| CN110291199B (zh) | 2016-10-03 | 2023-12-22 | 美国陶氏益农公司 | 用于转基因表达的植物启动子 |
| US10519459B2 (en) | 2016-10-03 | 2019-12-31 | Dow Agrosciences Llc | Plant promoter from Panicum virgatum |
| CN111278276B (zh) | 2017-06-28 | 2023-05-26 | 美国陶氏益农公司 | 用于转基因表达的植物启动子 |
| CN111527212B (zh) | 2017-08-31 | 2024-04-09 | 科迪华农业科技有限责任公司 | 使用来自叶绿素结合Ab基因的调控元件表达转基因的组合物和方法 |
| JPWO2020032261A1 (ja) * | 2018-08-10 | 2021-08-10 | 協和発酵バイオ株式会社 | エイコサペンタエン酸を生産する微生物及びエイコサペンタエン酸の製造法 |
| WO2020032258A1 (ja) * | 2018-08-10 | 2020-02-13 | 協和発酵バイオ株式会社 | 多価不飽和脂肪酸を生産する微生物及び多価不飽和脂肪酸の製造法 |
| CN109852724A (zh) * | 2019-04-03 | 2019-06-07 | 深圳出入境检验检疫局食品检验检疫技术中心 | 转基因油菜品系oxy235检测方法、试剂和试剂盒 |
| EP4430063A1 (en) | 2021-11-09 | 2024-09-18 | Benson Hill, Inc. | Promoter elements for improved polynucleotide expression in plants |
| US20250051792A1 (en) | 2021-12-15 | 2025-02-13 | Benson Hill, Inc. | Spatio-temporal promoters for polynucleotide expression in plants |
| US20240035100A1 (en) * | 2022-06-27 | 2024-02-01 | Monsanto Technology Llc | Soybean transgenic event gm_csm63770 and methods for detection and uses thereof |
| WO2024127362A1 (en) | 2022-12-15 | 2024-06-20 | Benson Hill, Inc. | Spatio-temporal promoters for polynucleotide expression in plants |
| WO2025238190A1 (en) | 2024-05-15 | 2025-11-20 | Dsm Ip Assets B.V. | Spray-dried powders having high pufa content |
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| NL8300698A (nl) | 1983-02-24 | 1984-09-17 | Univ Leiden | Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten. |
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| DE69231875T2 (de) | 1991-04-09 | 2001-10-04 | Unilever N.V., Rotterdam | Pflanzen-promoter involviert in der kontrolle der lipid-biosynthese in samen |
| US6210700B1 (en) | 1997-01-14 | 2001-04-03 | Novartis Nutrition Ag | Enhancement of transplant graft survival through nutritional immunomodulation with omega-9 fatty acid dietary supplement therapy |
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| US6566583B1 (en) | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| EP2042603A1 (en) * | 1998-11-17 | 2009-04-01 | Monsanto Technology, LLC | Phosphonate metabolizing plants |
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| US7217856B2 (en) | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US7211418B2 (en) | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US6784342B1 (en) | 1999-08-04 | 2004-08-31 | The University Of British Columbia | Regulation of embryonic transcription in plants |
| ATE414779T1 (de) | 1999-09-30 | 2008-12-15 | Japan Tobacco Inc | Vektoren zum transformieren von pflanzen |
| US20040049806A1 (en) * | 2000-05-24 | 2004-03-11 | Ljerka Kunst | Nucleic acid encoding a plant very long chain fatty acid biosynthetic enzyme |
| CA2409876C (en) | 2000-05-24 | 2012-01-03 | The University Of British Columbia | Gene regulatory region that promotes early seed-specific transcription |
| US20040172682A1 (en) | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
| PL1809118T3 (pl) * | 2004-11-04 | 2017-07-31 | Monsanto Technology Llc | Kompozycje oleju z nasion |
| WO2006135866A2 (en) | 2005-06-10 | 2006-12-21 | Martek Biosciences Corporation | Pufa polyketide synthase systems and uses thereof |
| BRPI0614476B1 (pt) * | 2005-08-01 | 2018-04-03 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada | Farinha de canola e ração animal |
| US7868228B2 (en) | 2006-01-31 | 2011-01-11 | Monsanto Technology Llc | Phosphopantetheinyl transferases from bacteria |
| MX340759B (es) * | 2006-03-15 | 2015-03-11 | Dsm Ip Assets B V * | Aceites de semillas vegetales que contienen ácidos grasos poli-insaturados. |
| SG10201501004UA (en) * | 2006-08-29 | 2015-04-29 | Dsm Ip Assets Bv | USE OF DPA(n-6) OILS IN INFANT FORMULA |
| CA2709067A1 (en) | 2007-12-21 | 2009-07-09 | Zhifu Zheng | Diacylglycerol acyltransferase 2 genes and proteins encoded thereby from algae |
| US8455035B2 (en) * | 2008-04-25 | 2013-06-04 | Basf Plant Science Gmbh | Plant seed oil |
| US9090902B2 (en) * | 2008-08-26 | 2015-07-28 | Basf Plant Science Gmbh | Nucleic acids encoding desaturases and modified plant oil |
| WO2010108114A2 (en) * | 2009-03-19 | 2010-09-23 | Martek Biosciences Corporation | Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof |
| TW201144442A (en) * | 2010-05-17 | 2011-12-16 | Dow Agrosciences Llc | Production of DHA and other LC-PUFAs in plants |
-
2011
- 2011-05-16 TW TW100117098A patent/TW201144442A/zh unknown
- 2011-05-17 HU HUE11784114A patent/HUE036182T2/hu unknown
- 2011-05-17 NO NO11784114A patent/NO2571994T3/no unknown
- 2011-05-17 AU AU2011256209A patent/AU2011256209B2/en not_active Ceased
- 2011-05-17 WO PCT/US2011/036869 patent/WO2011146524A1/en not_active Ceased
- 2011-05-17 EP EP11784114.8A patent/EP2571994B1/en not_active Not-in-force
- 2011-05-17 US US13/698,412 patent/US20130150599A1/en not_active Abandoned
- 2011-05-17 UA UAA201213968A patent/UA116613C2/uk unknown
- 2011-05-17 EP EP19162968.2A patent/EP3517617A1/en not_active Withdrawn
- 2011-05-17 PH PH1/2012/502267A patent/PH12012502267A1/en unknown
- 2011-05-17 MX MX2012013401A patent/MX345243B/es active IP Right Grant
- 2011-05-17 BR BR112012029255A patent/BR112012029255A2/pt not_active IP Right Cessation
- 2011-05-17 ES ES11784114.8T patent/ES2656217T3/es active Active
- 2011-05-17 SG SG2012083796A patent/SG185572A1/en unknown
- 2011-05-17 EA EA201291223A patent/EA201291223A1/ru unknown
- 2011-05-17 PL PL11784114T patent/PL2571994T3/pl unknown
- 2011-05-17 CN CN201180035255.6A patent/CN103080319B/zh not_active Expired - Fee Related
- 2011-05-17 EP EP17206033.7A patent/EP3354739A1/en not_active Withdrawn
- 2011-05-17 AR ARP110101691A patent/AR081201A1/es not_active Application Discontinuation
- 2011-05-17 KR KR1020127033006A patent/KR102184432B1/ko active Active
- 2011-05-17 CA CA3161375A patent/CA3161375A1/en active Pending
- 2011-05-17 MY MYPI2012004965A patent/MY165098A/en unknown
- 2011-05-17 CN CN201510664546.1A patent/CN105296511A/zh active Pending
- 2011-05-17 CA CA2799559A patent/CA2799559C/en active Active
- 2011-05-17 JP JP2013511303A patent/JP6059138B2/ja not_active Expired - Fee Related
- 2011-05-17 NZ NZ604479A patent/NZ604479A/en not_active IP Right Cessation
- 2011-05-17 PT PT117841148T patent/PT2571994T/pt unknown
-
2012
- 2012-11-15 IL IL223045A patent/IL223045A0/en unknown
- 2012-11-16 CL CL2012003210A patent/CL2012003210A1/es unknown
-
2017
- 2017-11-29 US US15/825,107 patent/US10669554B2/en not_active Expired - Fee Related
-
2018
- 2018-09-24 US US16/139,534 patent/US20190010510A1/en not_active Abandoned
-
2020
- 2020-06-02 US US16/890,740 patent/US11168332B2/en not_active Expired - Fee Related
-
2022
- 2022-02-11 US US17/669,945 patent/US12006504B2/en active Active
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