JP2013527765A5 - - Google Patents
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- JP2013527765A5 JP2013527765A5 JP2013509041A JP2013509041A JP2013527765A5 JP 2013527765 A5 JP2013527765 A5 JP 2013527765A5 JP 2013509041 A JP2013509041 A JP 2013509041A JP 2013509041 A JP2013509041 A JP 2013509041A JP 2013527765 A5 JP2013527765 A5 JP 2013527765A5
- Authority
- JP
- Japan
- Prior art keywords
- zinc finger
- amino acid
- residue
- terminal
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34372910P | 2010-05-03 | 2010-05-03 | |
| US61/343,729 | 2010-05-03 | ||
| PCT/US2011/000758 WO2011139349A1 (en) | 2010-05-03 | 2011-05-02 | Compositions for linking zinc finger modules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013527765A JP2013527765A (ja) | 2013-07-04 |
| JP2013527765A5 true JP2013527765A5 (enExample) | 2015-09-24 |
| JP5898179B2 JP5898179B2 (ja) | 2016-04-06 |
Family
ID=44903931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509041A Expired - Fee Related JP5898179B2 (ja) | 2010-05-03 | 2011-05-02 | ジンクフィンガーモジュールを連結するための組成物 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8772453B2 (enExample) |
| EP (2) | EP2566972B1 (enExample) |
| JP (1) | JP5898179B2 (enExample) |
| KR (2) | KR101974036B1 (enExample) |
| CN (1) | CN102959087B (enExample) |
| AU (1) | AU2011249019B2 (enExample) |
| CA (1) | CA2797189C (enExample) |
| CY (1) | CY1122636T1 (enExample) |
| DK (1) | DK2566972T3 (enExample) |
| ES (1) | ES2773052T3 (enExample) |
| HR (1) | HRP20200254T1 (enExample) |
| HU (1) | HUE048072T2 (enExample) |
| IL (1) | IL222632B (enExample) |
| LT (1) | LT2566972T (enExample) |
| PL (1) | PL2566972T3 (enExample) |
| PT (1) | PT2566972T (enExample) |
| SI (1) | SI2566972T1 (enExample) |
| WO (1) | WO2011139349A1 (enExample) |
Families Citing this family (79)
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| US20120196370A1 (en) | 2010-12-03 | 2012-08-02 | Fyodor Urnov | Methods and compositions for targeted genomic deletion |
| EP2596011B1 (en) | 2010-07-21 | 2018-10-03 | Sangamo Therapeutics, Inc. | Methods and compositions for modification of a hla locus |
| US9267123B2 (en) | 2011-01-05 | 2016-02-23 | Sangamo Biosciences, Inc. | Methods and compositions for gene correction |
| EP2737063B1 (en) | 2011-07-25 | 2016-06-01 | Sangamo BioSciences, Inc. | Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (cftr) gene |
| CA2852955C (en) | 2011-10-27 | 2021-02-16 | Sangamo Biosciences, Inc. | Methods and compositions for modification of the hprt locus |
| US9528107B2 (en) * | 2012-01-31 | 2016-12-27 | Pacific Biosciences Of California, Inc. | Compositions and methods for selection of nucleic acids |
| RU2639277C2 (ru) | 2012-02-29 | 2017-12-20 | Сангамо Байосайенсиз, Инк. | Способы и составы лечения болезни хантингтона |
| JP6329537B2 (ja) | 2012-07-11 | 2018-05-23 | サンガモ セラピューティクス， インコーポレイテッド | 生物学的薬剤の送達のための方法および組成物 |
| US10648001B2 (en) | 2012-07-11 | 2020-05-12 | Sangamo Therapeutics, Inc. | Method of treating mucopolysaccharidosis type I or II |
| CN104704110B (zh) | 2012-08-29 | 2018-06-01 | 桑格摩生物科学股份有限公司 | 用于治疗遗传性病状的方法和组合物 |
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| WO2014165612A2 (en) | 2013-04-05 | 2014-10-09 | Dow Agrosciences Llc | Methods and compositions for integration of an exogenous sequence within the genome of plants |
| JP6588438B2 (ja) | 2013-08-28 | 2019-10-09 | サンガモ セラピューティクス， インコーポレイテッド | Ｄｎａ結合ドメインと切断ドメインとを連結するための組成物 |
| AU2014337248B2 (en) | 2013-10-17 | 2020-09-24 | Sangamo Therapeutics, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering |
| US10117899B2 (en) | 2013-10-17 | 2018-11-06 | Sangamo Therapeutics, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells |
| EP3068905A4 (en) | 2013-11-11 | 2017-07-05 | Sangamo BioSciences, Inc. | Methods and compositions for treating huntington's disease |
| PT3068881T (pt) | 2013-11-13 | 2019-05-31 | Childrens Medical Center | Regulação da expressão de genes mediada por nucleases |
| US10072066B2 (en) | 2014-02-03 | 2018-09-11 | Sangamo Therapeutics, Inc. | Methods and compositions for treatment of a beta thalessemia |
| CA2942762C (en) | 2014-03-18 | 2023-10-17 | Sangamo Biosciences, Inc. | Methods and compositions for regulation of zinc finger protein expression |
| US10435685B2 (en) | 2014-08-19 | 2019-10-08 | Pacific Biosciences Of California, Inc. | Compositions and methods for enrichment of nucleic acids |
| US10808020B2 (en) | 2015-05-12 | 2020-10-20 | Sangamo Therapeutics, Inc. | Nuclease-mediated regulation of gene expression |
| US9957501B2 (en) | 2015-06-18 | 2018-05-01 | Sangamo Therapeutics, Inc. | Nuclease-mediated regulation of gene expression |
| WO2017011519A1 (en) | 2015-07-13 | 2017-01-19 | Sangamo Biosciences, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering |
| JP7128741B2 (ja) | 2015-12-18 | 2022-08-31 | サンガモ セラピューティクス， インコーポレイテッド | Ｔ細胞受容体の標的化破壊 |
| WO2017106537A2 (en) | 2015-12-18 | 2017-06-22 | Sangamo Biosciences, Inc. | Targeted disruption of the mhc cell receptor |
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| US10724020B2 (en) | 2016-02-02 | 2020-07-28 | Sangamo Therapeutics, Inc. | Compositions for linking DNA-binding domains and cleavage domains |
| MX2019002207A (es) | 2016-08-24 | 2019-07-15 | Sangamo Therapeutics Inc | Regulacion de la expresion genica usando nucleasas modificadas. |
| ES2901989T3 (es) | 2016-08-24 | 2022-03-24 | Sangamo Therapeutics Inc | Nucleasas específicas de objetivo modificadas |
| CA3039673A1 (en) | 2016-10-20 | 2018-04-26 | Sangamo Therapeutics, Inc. | Methods and compositions for the treatment of fabry disease |
| CA3041668A1 (en) | 2016-10-31 | 2018-05-03 | Sangamo Therapeutics, Inc. | Gene correction of scid-related genes in hematopoietic stem and progenitor cells |
| US11504389B2 (en) | 2016-12-01 | 2022-11-22 | Sangamo Therapeutics, Inc. | Tau modulators and methods and compositions for delivery thereof |
| TWI808079B (zh) | 2017-04-03 | 2023-07-11 | 美商編碼製藥公司 | 組織選擇性轉基因表現 |
| EP3615510B1 (en) | 2017-04-28 | 2024-03-27 | Acuitas Therapeutics, Inc. | Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| US11655275B2 (en) | 2017-05-03 | 2023-05-23 | Sangamo Therapeutics, Inc. | Methods and compositions for modification of a cystic fibrosis transmembrane conductance regulator (CFTR) gene |
| US11512287B2 (en) | 2017-06-16 | 2022-11-29 | Sangamo Therapeutics, Inc. | Targeted disruption of T cell and/or HLA receptors |
| BR112020002438A2 (pt) | 2017-08-08 | 2020-07-28 | Sangamo Therapeutics, Inc. | direcionamento celular mediado por receptores de antígenos quiméricos |
| IL274323B2 (en) | 2017-11-09 | 2024-10-01 | Sangamo Therapeutics Inc | Genetic modification of cytokine inducible sh2-containing protein (cish) gene |
| MA50942A (fr) | 2017-12-01 | 2020-10-07 | Encoded Therapeutics Inc | Protéines de liaison à l'adn modifiées |
| CN111954540A (zh) | 2018-02-08 | 2020-11-17 | 桑格摩生物治疗股份有限公司 | 工程化靶标特异性核酸酶 |
| EP3781587A4 (en) * | 2018-04-18 | 2022-03-30 | Sangamo Therapeutics, Inc. | ZINC FINGER PROTEIN COMPOSITIONS FOR THE MODULATION OF HUNTINGTINE (HTT) |
| US11690921B2 (en) | 2018-05-18 | 2023-07-04 | Sangamo Therapeutics, Inc. | Delivery of target specific nucleases |
| WO2020041249A1 (en) | 2018-08-23 | 2020-02-27 | Sangamo Therapeutics, Inc. | Engineered target specific base editors |
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| WO2020061426A2 (en) | 2018-09-21 | 2020-03-26 | Acuitas Therapeutics, Inc. | Systems and methods for manufacturing lipid nanoparticles and liposomes |
| US12318427B2 (en) | 2018-10-02 | 2025-06-03 | Sangamo Therapeutics, Inc. | Methods and compositions for modulation of tau proteins |
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| DK3908568T3 (da) | 2019-01-11 | 2024-08-26 | Acuitas Therapeutics Inc | Lipider til lipidnanopartikellevering af aktivstoffer |
| EP3826664A4 (en) | 2019-02-06 | 2022-10-26 | Sangamo Therapeutics, Inc. | Method for the treatment of mucopolysaccharidosis type i |
| WO2020205838A1 (en) | 2019-04-02 | 2020-10-08 | Sangamo Therapeutics, Inc. | Methods for the treatment of beta-thalassemia |
| TW202521561A (zh) | 2019-04-23 | 2025-06-01 | 美商聖加莫治療股份有限公司 | 染色體9開放讀框72基因表現之調節子及其用途 |
| WO2020237045A1 (en) | 2019-05-21 | 2020-11-26 | Sangamo Therapeutics, Inc. | Controlled transgene expression in regulatory t cells |
| EP3976798B1 (en) | 2019-05-29 | 2025-12-17 | Encoded Therapeutics, Inc. | Compositions and methods for selective gene regulation |
| WO2021028359A1 (en) | 2019-08-09 | 2021-02-18 | Sangamo Therapeutics France | Controlled expression of chimeric antigen receptors in t cells |
| AU2020356962A1 (en) | 2019-10-02 | 2022-04-14 | Sangamo Therapeutics, Inc. | Zinc finger protein transcription factors for repressing alpha-synuclein expression |
| JP2022550608A (ja) | 2019-10-02 | 2022-12-02 | サンガモ セラピューティクス， インコーポレイテッド | プリオン病の治療のためのジンクフィンガータンパク質転写因子 |
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| UY39036A (es) | 2020-01-22 | 2021-08-31 | Sangamo Therapeutics Inc | Factores de transcripción de proteína de dedos de zinc para represión de la expresión tau |
| US20230174612A1 (en) * | 2020-04-09 | 2023-06-08 | The Regents Of The University Of California | Notch receptors with zinc finger-containing transcriptional effector |
| US11976019B2 (en) | 2020-07-16 | 2024-05-07 | Acuitas Therapeutics, Inc. | Cationic lipids for use in lipid nanoparticles |
| WO2022046760A2 (en) | 2020-08-25 | 2022-03-03 | Kite Pharma, Inc. | T cells with improved functionality |
| KR20230074519A (ko) | 2020-09-25 | 2023-05-30 | 상가모 테라퓨틱스, 인코포레이티드 | 핵염기 편집을 위한 아연 핑거 융합 단백질 |
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| WO2023081756A1 (en) | 2021-11-03 | 2023-05-11 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Precise genome editing using retrons |
| KR20240123832A (ko) | 2021-12-16 | 2024-08-14 | 아퀴타스 테라퓨틱스 인크. | 지질 나노입자 제형에 사용하기 위한 지질 |
| JP2025504606A (ja) | 2021-12-22 | 2025-02-13 | サンガモ セラピューティクス， インコーポレイテッド | 核酸塩基編集のための新規ジンクフィンガー融合タンパク質 |
| WO2023141602A2 (en) | 2022-01-21 | 2023-07-27 | Renagade Therapeutics Management Inc. | Engineered retrons and methods of use |
| JP2025516294A (ja) | 2022-05-01 | 2025-05-27 | エヌクロマ・バイオ，インコーポレーテッド | Ｐｃｓｋ９発現のエピジェネティック調節のための組成物及び方法 |
| CA3260474A1 (en) | 2022-06-23 | 2023-12-28 | Chroma Medicine, Inc. | COMPOSITIONS AND METHODS OF EPIGENETIC REGULATION OF B2M EXPRESSION |
| US20250387514A1 (en) | 2022-06-23 | 2025-12-25 | Nchroma Bio, Inc. | Compositions and methods for epigenetic regulation of trac expression |
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2011
- 2011-05-02 SI SI201131844T patent/SI2566972T1/sl unknown
- 2011-05-02 US US13/068,102 patent/US8772453B2/en active Active
- 2011-05-02 PL PL11777690T patent/PL2566972T3/pl unknown
- 2011-05-02 CN CN201180022329.2A patent/CN102959087B/zh active Active
- 2011-05-02 DK DK11777690.6T patent/DK2566972T3/da active
- 2011-05-02 EP EP11777690.6A patent/EP2566972B1/en active Active
- 2011-05-02 HU HUE11777690A patent/HUE048072T2/hu unknown
- 2011-05-02 KR KR1020187017770A patent/KR101974036B1/ko active Active
- 2011-05-02 ES ES11777690T patent/ES2773052T3/es active Active
- 2011-05-02 EP EP19211724.0A patent/EP3636766A1/en active Pending
- 2011-05-02 WO PCT/US2011/000758 patent/WO2011139349A1/en not_active Ceased
- 2011-05-02 PT PT117776906T patent/PT2566972T/pt unknown
- 2011-05-02 HR HRP20200254TT patent/HRP20200254T1/hr unknown
- 2011-05-02 AU AU2011249019A patent/AU2011249019B2/en active Active
- 2011-05-02 JP JP2013509041A patent/JP5898179B2/ja not_active Expired - Fee Related
- 2011-05-02 LT LTEP11777690.6T patent/LT2566972T/lt unknown
- 2011-05-02 CA CA2797189A patent/CA2797189C/en active Active
- 2011-05-02 KR KR1020127028770A patent/KR20130073887A/ko not_active Ceased
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2012
- 2012-10-23 IL IL222632A patent/IL222632B/en active IP Right Grant
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2014
- 2014-06-04 US US14/296,159 patent/US9163245B2/en active Active
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2020
- 2020-02-14 CY CY20201100140T patent/CY1122636T1/el unknown
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