JP2013525454A5 - - Google Patents
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- Publication number
- JP2013525454A5 JP2013525454A5 JP2013508243A JP2013508243A JP2013525454A5 JP 2013525454 A5 JP2013525454 A5 JP 2013525454A5 JP 2013508243 A JP2013508243 A JP 2013508243A JP 2013508243 A JP2013508243 A JP 2013508243A JP 2013525454 A5 JP2013525454 A5 JP 2013525454A5
- Authority
- JP
- Japan
- Prior art keywords
- fluoro
- salt
- prepare
- mixing
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCCC(CCC*)*c(ccc(N(C[C@](CNC(C)=O)O1)C1=O)c1)c1F Chemical compound CCCC(CCC*)*c(ccc(N(C[C@](CNC(C)=O)O1)C1=O)c1)c1F 0.000 description 1
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32989210P | 2010-04-30 | 2010-04-30 | |
| US61/329,892 | 2010-04-30 | ||
| US35985110P | 2010-06-30 | 2010-06-30 | |
| US61/359,851 | 2010-06-30 | ||
| US37557610P | 2010-08-20 | 2010-08-20 | |
| US61/375,576 | 2010-08-20 | ||
| US38953410P | 2010-10-04 | 2010-10-04 | |
| US61/389,534 | 2010-10-04 | ||
| US42144210P | 2010-12-09 | 2010-12-09 | |
| US61/421,442 | 2010-12-09 | ||
| PCT/US2011/034278 WO2011137222A1 (en) | 2010-04-30 | 2011-04-28 | Processes for preparing linezolid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013525454A JP2013525454A (ja) | 2013-06-20 |
| JP2013525454A5 true JP2013525454A5 (cg-RX-API-DMAC7.html) | 2014-06-19 |
| JP5865898B2 JP5865898B2 (ja) | 2016-02-17 |
Family
ID=44861911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508243A Expired - Fee Related JP5865898B2 (ja) | 2010-04-30 | 2011-04-28 | リネゾリドを調製するためのプロセス |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9206141B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2899185B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5865898B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20130108975A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103025730A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011245302A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112012027901A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2798101A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL222770A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2012012627A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2012151303A (cg-RX-API-DMAC7.html) |
| SG (1) | SG185103A1 (cg-RX-API-DMAC7.html) |
| TW (1) | TWI535715B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011137222A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201208382B (cg-RX-API-DMAC7.html) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103025730A (zh) * | 2010-04-30 | 2013-04-03 | 印第安纳大学研究及科技有限公司 | 制备利奈唑胺的方法 |
| EP2595968B1 (en) | 2011-02-24 | 2015-09-09 | Lee Pharma Limited | Novel process for preparation of linezolid and its novel intermediates |
| WO2013072923A1 (en) * | 2011-09-19 | 2013-05-23 | Cadila Healthcare Limited | Process for the preparation of crystalline linezolid |
| CN103254148B (zh) * | 2012-02-15 | 2016-04-13 | 浙江海正药业股份有限公司 | 利奈唑胺中间体的制备方法 |
| CN103288814B (zh) * | 2012-02-24 | 2016-07-06 | 国药集团国瑞药业有限公司 | 一种利伐沙班中间体的制备方法 |
| EP2834235A1 (en) | 2012-04-06 | 2015-02-11 | Indiana University Research and Technology Corporation | Processes for preparing rivaroxaban |
| ITMI20120655A1 (it) * | 2012-04-19 | 2013-10-20 | Bioindustria Lab Italiano M Edicinali Spa | Procedimento per la preparazione di linezolid |
| AR090844A1 (es) * | 2012-04-27 | 2014-12-10 | Actelion Pharmaceuticals Ltd | Proceso para elaborar derivados de naftiridina |
| CN103626712B (zh) * | 2012-08-23 | 2016-06-01 | 重庆药友制药有限责任公司 | 一种用于制备利奈唑胺的中间体及其制备方法 |
| WO2014045292A1 (en) * | 2012-09-20 | 2014-03-27 | Symed Labs Limited | Improved process for the preparation of linezolid intermediate |
| WO2014170908A1 (en) * | 2013-04-18 | 2014-10-23 | Nosch Labs Private Limited | Process for preparation of oxazolidinone derivatives |
| EP3250568A4 (en) * | 2016-04-21 | 2018-08-01 | Optimus Drugs Pvt Ltd | An improved process for the preparation of linezolid |
| CN110194750A (zh) * | 2019-06-19 | 2019-09-03 | 四川美大康华康药业有限公司 | 一种利奈唑胺的制备方法及精制方法 |
| CN112159368A (zh) * | 2020-07-07 | 2021-01-01 | 杭州杜易科技有限公司 | 一种利奈唑胺中间体的合成方法 |
| RU2760198C1 (ru) * | 2020-12-16 | 2021-11-22 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" | Однореакторный способ получения полупродукта для синтеза линезолида |
| CN115684399B (zh) * | 2022-10-27 | 2024-12-20 | 贵州健安德科技有限公司 | 一种氯醇亚胺的高效液相检测及含量测定方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3725450A (en) * | 1970-10-05 | 1973-04-03 | Gen Mills Chem Inc | Process for the preparation of isocyanates from acyl azides |
| US4937331A (en) | 1988-03-25 | 1990-06-26 | President And Fellows Of Harvard College | Chiral azetidinone epoxides |
| DE4119611A1 (de) * | 1991-06-14 | 1992-12-17 | Bayer Ag | Mittel zur bekaempfung von schaedlingen auf basis substituierter oxazolidinone, neue substituierte oxazolidinone, deren herstellung und verwendung |
| TW380137B (en) * | 1994-03-04 | 2000-01-21 | Merck & Co Inc | Process for making an epoxide |
| DE19542148A1 (de) * | 1995-11-11 | 1997-05-15 | Hoechst Ag | Verfahren zur Herstellung von fluorierten Aromaten |
| NZ504372A (en) | 1997-11-07 | 2002-12-20 | Upjohn Co | Process to produce N-[3-fluoro-4(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinones |
| US6921825B2 (en) | 1998-09-16 | 2005-07-26 | King Pharmaceuticuals Research & Development, Inc. | Adenosine A3 receptor modulators |
| US6444813B2 (en) * | 2000-02-02 | 2002-09-03 | Pharmacia & Upjohn Company | Linezolid-crystal form II |
| AR027261A1 (es) | 2000-02-02 | 2003-03-19 | Upjohn Co | Linezolid forma cristalina ii |
| SE0001866D0 (sv) * | 2000-05-18 | 2000-05-18 | Astrazeneca Ab | A new process |
| ATE321024T1 (de) | 2000-10-17 | 2006-04-15 | Pharmacia & Upjohn Co Llc | Verfahren zur herstellung von oxazolidinonverbindungen |
| ATE338035T1 (de) | 2001-06-05 | 2006-09-15 | Boehringer Ingelheim Pharma | 1,4-disubstituierte benzokondensierte cycloalkyl harnstoffverbindungen |
| ES2294494T3 (es) | 2004-04-19 | 2008-04-01 | Symed Labs Limited | Un nuevo procedimiento para la preparacion de linezolid y compuestos relacionados. |
| EP1768967B1 (en) | 2004-07-20 | 2009-04-22 | Symed Labs Limited | Novel intermediates for linezolid and related compounds |
| WO2006091731A2 (en) | 2005-02-24 | 2006-08-31 | Teva Pharmaceutical Industries Ltd. | Processes for the preparation of linezolid intermediate |
| WO2007011684A2 (en) | 2005-07-15 | 2007-01-25 | Cyclics Corporation | Macrocyclic polyester oligomers as carriers and/or flow modifier additives for thermoplastics |
| AU2007235635A1 (en) | 2006-04-07 | 2007-10-18 | Pfizer Products Inc. | Process for preparing linezolid |
| CN101220001A (zh) | 2008-01-25 | 2008-07-16 | 浙江博泰化工有限公司 | 一种利奈唑酮的合成方法 |
| CN101638392B (zh) | 2009-08-24 | 2012-05-16 | 浙江工业大学 | 一种列奈唑酮的制备方法 |
| CN103025730A (zh) * | 2010-04-30 | 2013-04-03 | 印第安纳大学研究及科技有限公司 | 制备利奈唑胺的方法 |
-
2011
- 2011-04-28 CN CN2011800328913A patent/CN103025730A/zh active Pending
- 2011-04-28 EP EP14197369.3A patent/EP2899185B1/en not_active Not-in-force
- 2011-04-28 BR BR112012027901A patent/BR112012027901A2/pt not_active IP Right Cessation
- 2011-04-28 MX MX2012012627A patent/MX2012012627A/es not_active Application Discontinuation
- 2011-04-28 SG SG2012080321A patent/SG185103A1/en unknown
- 2011-04-28 AU AU2011245302A patent/AU2011245302A1/en not_active Abandoned
- 2011-04-28 US US13/695,211 patent/US9206141B2/en not_active Expired - Fee Related
- 2011-04-28 CA CA2798101A patent/CA2798101A1/en not_active Abandoned
- 2011-04-28 EP EP11775554.6A patent/EP2563781B1/en not_active Not-in-force
- 2011-04-28 JP JP2013508243A patent/JP5865898B2/ja not_active Expired - Fee Related
- 2011-04-28 KR KR1020127029523A patent/KR20130108975A/ko not_active Withdrawn
- 2011-04-28 RU RU2012151303/04A patent/RU2012151303A/ru not_active Application Discontinuation
- 2011-04-28 WO PCT/US2011/034278 patent/WO2011137222A1/en not_active Ceased
- 2011-04-29 TW TW100115216A patent/TWI535715B/zh not_active IP Right Cessation
-
2012
- 2012-10-30 IL IL222770A patent/IL222770A0/en unknown
- 2012-11-07 ZA ZA2012/08382A patent/ZA201208382B/en unknown
-
2015
- 2015-09-23 US US14/862,841 patent/US9656973B2/en not_active Expired - Fee Related