JP2013523846A5 - - Google Patents
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- JP2013523846A5 JP2013523846A5 JP2013504075A JP2013504075A JP2013523846A5 JP 2013523846 A5 JP2013523846 A5 JP 2013523846A5 JP 2013504075 A JP2013504075 A JP 2013504075A JP 2013504075 A JP2013504075 A JP 2013504075A JP 2013523846 A5 JP2013523846 A5 JP 2013523846A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- disorder
- condition
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 claims 24
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 3
- 208000035475 disorder Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000022873 Ocular disease Diseases 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 1
- 201000010183 Papilledema Diseases 0.000 claims 1
- 206010038886 Retinal oedema Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 206010064930 age-related macular degeneration Diseases 0.000 claims 1
- 230000033115 angiogenesis Effects 0.000 claims 1
- 210000002987 choroid plexus Anatomy 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000002780 macular degeneration Diseases 0.000 claims 1
- 239000000651 prodrug Substances 0.000 claims 1
- 229940002612 prodrug Drugs 0.000 claims 1
- 201000011195 retinal edema Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 0 C*(CCNCc1ccc(-c2cc(nccc3CCOc(ccc(NC(NC4CC4)=O)c4)c4F)c3[s]2)nc1)=O Chemical compound C*(CCNCc1ccc(-c2cc(nccc3CCOc(ccc(NC(NC4CC4)=O)c4)c4F)c3[s]2)nc1)=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32480310P | 2010-04-16 | 2010-04-16 | |
| US61/324,803 | 2010-04-16 | ||
| PCT/CA2011/000390 WO2011127565A1 (en) | 2010-04-16 | 2011-04-08 | Inhibitors of protein tyrosine kinase activity and use thereof to treat ophthalmic disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013523846A JP2013523846A (ja) | 2013-06-17 |
| JP2013523846A5 true JP2013523846A5 (https=) | 2014-05-15 |
Family
ID=44788641
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013504076A Ceased JP2013525286A (ja) | 2010-04-16 | 2011-04-08 | タンパク質チロシンキナーゼ活性の阻害剤 |
| JP2013504075A Ceased JP2013523846A (ja) | 2010-04-16 | 2011-04-08 | タンパク質チロシンキナーゼ活性の阻害剤および眼部の障害を治療するためのそれらの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013504076A Ceased JP2013525286A (ja) | 2010-04-16 | 2011-04-08 | タンパク質チロシンキナーゼ活性の阻害剤 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US8455484B2 (https=) |
| EP (2) | EP2563794A4 (https=) |
| JP (2) | JP2013525286A (https=) |
| KR (2) | KR20130058006A (https=) |
| CN (2) | CN103025740B (https=) |
| AR (2) | AR080875A1 (https=) |
| AU (2) | AU2011241422B2 (https=) |
| CA (2) | CA2796054A1 (https=) |
| CO (2) | CO6630193A2 (https=) |
| EA (2) | EA201291052A1 (https=) |
| MX (2) | MX2012012031A (https=) |
| MY (1) | MY157319A (https=) |
| NZ (2) | NZ602948A (https=) |
| PH (2) | PH12012502070A1 (https=) |
| SG (2) | SG184883A1 (https=) |
| TW (2) | TW201204735A (https=) |
| UA (1) | UA108878C2 (https=) |
| WO (2) | WO2011127565A1 (https=) |
| ZA (2) | ZA201207482B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0816064B8 (pt) * | 2007-08-29 | 2021-05-25 | Methylgene Inc | composto inibidor da atividade de proteína tirosina quinase, seu uso, e composição farmacêutica |
| BRPI0908573A2 (pt) * | 2008-03-05 | 2012-12-25 | Methylgene Inc | inibidores da atividade de proteÍna tirosina quinase |
| US8455484B2 (en) * | 2010-04-16 | 2013-06-04 | Methylgene Inc. | Selected inhibitors of protein tyrosine kinase activity |
| WO2013044361A1 (en) * | 2011-09-30 | 2013-04-04 | Methylgene Inc. | Inhibitors of protein tyrosine kinase activity |
| US20130096135A1 (en) * | 2011-09-30 | 2013-04-18 | Methylgene Inc. | Selected Inhibitors of Protein Tyrosine Kinase Activity |
| WO2013044360A1 (en) * | 2011-09-30 | 2013-04-04 | Methylgene Inc. | Inhibitors of protein tyrosine kinase activity |
| CA2857603C (en) | 2011-12-15 | 2016-08-02 | Pfizer Limited | Sulfonamide derivatives |
| US10544117B2 (en) | 2014-09-10 | 2020-01-28 | Temple University—Of the Commonwealth System of Higher Education | 5-hydroxytryptamine receptor 7 activity modulators and their method of use |
| US20180221365A1 (en) * | 2015-05-12 | 2018-08-09 | Temple University-Of The Commonwealth System Of Higher Education | Novel sigma-2 receptor binders and their method of use |
| JP6664170B2 (ja) * | 2015-08-31 | 2020-03-13 | 広栄化学工業株式会社 | アミノヒドロキシピリジン化合物の製造方法 |
| CN108530464B (zh) * | 2017-03-02 | 2020-10-27 | 深圳海王医药科技研究院有限公司 | 一种多靶点激酶抑制剂 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050020619A1 (en) * | 2003-07-24 | 2005-01-27 | Patrick Betschmann | Thienopyridine kinase inhibitors |
| KR101257343B1 (ko) * | 2004-07-30 | 2013-04-23 | 메틸진 인코포레이티드 | Ｖｅｇｆ 수용체 및 ｈｇｆ 수용체 신호전달 억제제 |
| AU2006229343A1 (en) * | 2005-03-28 | 2006-10-05 | Kirin Pharma Kabushiki Kaisha | Thienopyridine derivative, or quinoline derivative, or quinazoline derivative, having c-Met autophosphorylation inhibiting potency |
| JO2787B1 (en) * | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
| AU2006313456B2 (en) * | 2005-05-20 | 2011-06-23 | Methylgene Inc. | Inhibitors of VEGF receptor and HGF receptor signaling |
| CN101796055B (zh) * | 2005-05-20 | 2013-09-04 | 梅特希尔基因公司 | Vegf受体和hgf受体信号的抑制剂 |
| BRPI0816064B8 (pt) * | 2007-08-29 | 2021-05-25 | Methylgene Inc | composto inibidor da atividade de proteína tirosina quinase, seu uso, e composição farmacêutica |
| US8907091B2 (en) * | 2007-08-29 | 2014-12-09 | Methylgene Inc. | Processes and intermediates for preparing fused heterocyclic kinase inhibitors |
| BRPI0908573A2 (pt) * | 2008-03-05 | 2012-12-25 | Methylgene Inc | inibidores da atividade de proteÍna tirosina quinase |
| US8455484B2 (en) * | 2010-04-16 | 2013-06-04 | Methylgene Inc. | Selected inhibitors of protein tyrosine kinase activity |
| WO2013044361A1 (en) * | 2011-09-30 | 2013-04-04 | Methylgene Inc. | Inhibitors of protein tyrosine kinase activity |
-
2011
- 2011-04-08 US US13/082,944 patent/US8455484B2/en not_active Expired - Fee Related
- 2011-04-08 TW TW100112308A patent/TW201204735A/zh unknown
- 2011-04-08 EP EP20110768305 patent/EP2563794A4/en not_active Withdrawn
- 2011-04-08 KR KR1020127030161A patent/KR20130058006A/ko not_active Withdrawn
- 2011-04-08 WO PCT/CA2011/000390 patent/WO2011127565A1/en not_active Ceased
- 2011-04-08 SG SG2012076733A patent/SG184883A1/en unknown
- 2011-04-08 CA CA2796054A patent/CA2796054A1/en not_active Abandoned
- 2011-04-08 SG SG2012076725A patent/SG184882A1/en unknown
- 2011-04-08 PH PH1/2012/502070A patent/PH12012502070A1/en unknown
- 2011-04-08 NZ NZ602948A patent/NZ602948A/en not_active IP Right Cessation
- 2011-04-08 NZ NZ602954A patent/NZ602954A/en not_active IP Right Cessation
- 2011-04-08 AU AU2011241422A patent/AU2011241422B2/en not_active Ceased
- 2011-04-08 MX MX2012012031A patent/MX2012012031A/es active IP Right Grant
- 2011-04-08 AR ARP110101195A patent/AR080875A1/es unknown
- 2011-04-08 JP JP2013504076A patent/JP2013525286A/ja not_active Ceased
- 2011-04-08 CA CA2796008A patent/CA2796008A1/en not_active Abandoned
- 2011-04-08 KR KR1020127029841A patent/KR20130100234A/ko not_active Withdrawn
- 2011-04-08 UA UAA201211687A patent/UA108878C2/ru unknown
- 2011-04-08 CN CN201180029735.1A patent/CN103025740B/zh not_active Expired - Fee Related
- 2011-04-08 WO PCT/CA2011/000394 patent/WO2011127567A1/en not_active Ceased
- 2011-04-08 EP EP11768307.8A patent/EP2563795A4/en not_active Withdrawn
- 2011-04-08 AU AU2011241420A patent/AU2011241420B2/en not_active Ceased
- 2011-04-08 MY MYPI2012004621A patent/MY157319A/en unknown
- 2011-04-08 EA EA201291052A patent/EA201291052A1/ru unknown
- 2011-04-08 AR ARP110101191A patent/AR080871A1/es unknown
- 2011-04-08 TW TW100112307A patent/TW201204734A/zh unknown
- 2011-04-08 US US13/082,923 patent/US8906852B2/en not_active Expired - Fee Related
- 2011-04-08 CN CN2011800297313A patent/CN102947315A/zh active Pending
- 2011-04-08 EA EA201291055A patent/EA201291055A1/ru unknown
- 2011-04-08 JP JP2013504075A patent/JP2013523846A/ja not_active Ceased
- 2011-04-08 MX MX2012012032A patent/MX2012012032A/es not_active Application Discontinuation
- 2011-04-08 PH PH1/2012/502073A patent/PH12012502073A1/en unknown
-
2012
- 2012-10-05 ZA ZA2012/07482A patent/ZA201207482B/en unknown
- 2012-10-09 ZA ZA2012/07557A patent/ZA201207557B/en unknown
- 2012-11-15 CO CO12207310A patent/CO6630193A2/es active IP Right Grant
- 2012-11-15 CO CO12207317A patent/CO6640224A2/es active IP Right Grant
-
2014
- 2014-06-18 US US14/308,408 patent/US20140315801A1/en not_active Abandoned
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