JP2013523192A5 - - Google Patents
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- Publication number
- JP2013523192A5 JP2013523192A5 JP2013505204A JP2013505204A JP2013523192A5 JP 2013523192 A5 JP2013523192 A5 JP 2013523192A5 JP 2013505204 A JP2013505204 A JP 2013505204A JP 2013505204 A JP2013505204 A JP 2013505204A JP 2013523192 A5 JP2013523192 A5 JP 2013523192A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- slurry
- kcl
- compound
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 32
- 150000001875 compounds Chemical class 0.000 description 32
- 239000002002 slurry Substances 0.000 description 22
- 239000000243 solution Substances 0.000 description 20
- PHZLMBHDXVLRIX-UHFFFAOYSA-M potassium lactate Chemical compound [K+].CC(O)C([O-])=O PHZLMBHDXVLRIX-UHFFFAOYSA-M 0.000 description 15
- 239000001521 potassium lactate Substances 0.000 description 15
- 235000011085 potassium lactate Nutrition 0.000 description 15
- 229960001304 potassium lactate Drugs 0.000 description 15
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 239000011780 sodium chloride Substances 0.000 description 6
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 4
- 235000019658 bitter taste Nutrition 0.000 description 4
- 238000009835 boiling Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000008447 perception Effects 0.000 description 4
- 239000001540 sodium lactate Substances 0.000 description 4
- 229940005581 sodium lactate Drugs 0.000 description 4
- 235000011088 sodium lactate Nutrition 0.000 description 4
- 239000012085 test solution Substances 0.000 description 4
- 239000008156 Ringer's lactate solution Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32435110P | 2010-04-15 | 2010-04-15 | |
| US32435910P | 2010-04-15 | 2010-04-15 | |
| US32434610P | 2010-04-15 | 2010-04-15 | |
| US32436210P | 2010-04-15 | 2010-04-15 | |
| US32434510P | 2010-04-15 | 2010-04-15 | |
| US61/324,351 | 2010-04-15 | ||
| US61/324,362 | 2010-04-15 | ||
| US61/324,345 | 2010-04-15 | ||
| US61/324,346 | 2010-04-15 | ||
| US61/324,359 | 2010-04-15 | ||
| PCT/US2011/032782 WO2011130707A2 (en) | 2010-04-15 | 2011-04-15 | Compounds, compositions, and methods for reducing or eliminating bitter taste |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016155087A Division JP2017038594A (ja) | 2010-04-15 | 2016-08-05 | 苦味を低減または排除する化合物、組成物、および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013523192A JP2013523192A (ja) | 2013-06-17 |
| JP2013523192A5 true JP2013523192A5 (enExample) | 2016-11-24 |
Family
ID=44799371
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013505204A Withdrawn JP2013523192A (ja) | 2010-04-15 | 2011-04-15 | 苦味を低減または排除する化合物、組成物、および方法 |
| JP2016155087A Pending JP2017038594A (ja) | 2010-04-15 | 2016-08-05 | 苦味を低減または排除する化合物、組成物、および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016155087A Pending JP2017038594A (ja) | 2010-04-15 | 2016-08-05 | 苦味を低減または排除する化合物、組成物、および方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20130101684A1 (enExample) |
| EP (1) | EP2558067A4 (enExample) |
| JP (2) | JP2013523192A (enExample) |
| KR (1) | KR20130055601A (enExample) |
| CN (2) | CN105962259A (enExample) |
| AU (1) | AU2011239447B2 (enExample) |
| CA (1) | CA2796077A1 (enExample) |
| IL (1) | IL222423A (enExample) |
| MX (1) | MX2012011996A (enExample) |
| PE (1) | PE20130633A1 (enExample) |
| PH (1) | PH12012501970A1 (enExample) |
| RU (1) | RU2597438C2 (enExample) |
| WO (1) | WO2011130707A2 (enExample) |
| ZA (1) | ZA201208488B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1213887A1 (zh) | 2012-10-16 | 2016-07-15 | Janssen Pharmaceutica N.V. | RORγt的苯基连接的喹啉基调节剂 |
| WO2014062655A1 (en) | 2012-10-16 | 2014-04-24 | Janssen Pharmaceutica Nv | HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt |
| MY189505A (en) | 2012-10-16 | 2022-02-16 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of roryt |
| CA2927182A1 (en) | 2013-10-15 | 2015-04-23 | Janssen Pharmaceutica Nv | Quinolinyl modulators of ror.gamma.t |
| CA2926339A1 (en) | 2013-10-15 | 2015-04-23 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of roryt |
| US9284308B2 (en) | 2013-10-15 | 2016-03-15 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of RORγt |
| US10555941B2 (en) | 2013-10-15 | 2020-02-11 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of RORγt |
| US9221804B2 (en) | 2013-10-15 | 2015-12-29 | Janssen Pharmaceutica Nv | Secondary alcohol quinolinyl modulators of RORγt |
| US9403816B2 (en) | 2013-10-15 | 2016-08-02 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
| US9328095B2 (en) | 2013-10-15 | 2016-05-03 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of RORgammat |
| CN103588660B (zh) * | 2013-11-18 | 2016-06-01 | 中国医学科学院生物医学工程研究所 | 一种新型的酰基苯胺化合物及用途 |
| RU2623876C2 (ru) * | 2014-11-10 | 2017-06-29 | Александр Владимирович Диковский | Фармацевтическая композиция для лечения гиперлипидемии |
| BR112018001580A2 (pt) * | 2015-08-07 | 2018-09-18 | V Mane Fils | composição que compreende compostos de modulação de sabor, o uso dos mesmos e produto alimentício que compreende os mesmos |
| US10413543B2 (en) * | 2015-09-01 | 2019-09-17 | Sun Pharma Advanced Research Company Ltd. | Stable multiparticulate pharmaceutical composition of rosuvastatin |
| US20190059429A1 (en) | 2016-04-11 | 2019-02-28 | Nestec S.A. | Salt composition including serine |
| WO2018124284A1 (ja) * | 2016-12-28 | 2018-07-05 | 富山化学工業株式会社 | 医薬組成物 |
| CN109942537B (zh) * | 2018-03-03 | 2023-11-17 | 中国人民解放军第二军医大学 | 一类aldh2激动剂、制备方法及其用途 |
| EP3911632A1 (en) * | 2019-01-15 | 2021-11-24 | Empirico Inc. | Prodrugs of alox-15 inhibitors and methods of using the same |
| US20200260761A1 (en) * | 2019-02-14 | 2020-08-20 | Stanley Weller | Compositions and Methods for Use in Food Processing and Preservation |
| CN112079777B (zh) * | 2020-08-11 | 2022-05-06 | 中山大学 | 一种多取代4-氟吖啶衍生物及其制备方法 |
| JP2024510435A (ja) | 2021-03-18 | 2024-03-07 | シージェン インコーポレイテッド | 生体活性化合物の内部移行複合体からの選択的薬物放出 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL45396A0 (en) * | 1973-08-23 | 1974-11-29 | Beecham Group Ltd | Pharmaceutical compositions containing aryl aralkyl ether and thioether derivatives,certain such novel compounds and their preparation |
| JPH02129171A (ja) * | 1988-11-08 | 1990-05-17 | Nissan Chem Ind Ltd | ピラゾールカルボキサニリド誘導体及び有害生物防除剤 |
| CA2117284A1 (en) * | 1991-11-27 | 1993-06-10 | Bioresearch, Inc. | Specific eatable taste modifiers |
| US5925527A (en) * | 1997-02-04 | 1999-07-20 | Trega Biosciences, Inc. | Tricyclic Tetrahydroquinoline derivatives and tricyclic tetrahydroquinoline combinatorial libraries |
| US6297258B1 (en) | 1998-09-29 | 2001-10-02 | American Cyanamid Company | Substituted 3-cyanoquinolines |
| MY138097A (en) * | 2000-03-22 | 2009-04-30 | Du Pont | Insecticidal anthranilamides |
| US20050013835A1 (en) * | 2003-07-15 | 2005-01-20 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
| EP1659881B1 (en) * | 2003-08-06 | 2019-04-03 | Senomyx Inc. | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof |
| CA2827128C (en) * | 2003-08-06 | 2018-03-27 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds |
| DE102004041496A1 (de) * | 2004-08-27 | 2006-03-02 | Symrise Gmbh & Co. Kg | Hydroxybenzoesäureamide und deren Verwendung zur Maskierung von bitterem Geschmack |
| JP2008530017A (ja) * | 2005-02-04 | 2008-08-07 | セノミックス インコーポレイテッド | 食料用組成物のための風味調整剤として連結された有機部分を含む分子 |
| JP4688517B2 (ja) * | 2005-02-15 | 2011-05-25 | 小川香料株式会社 | 高甘味度甘味料の呈味改善剤 |
| CA2599992A1 (en) * | 2005-03-03 | 2006-09-08 | Sirtris Pharmaceuticals, Inc. | Acridine and quinoline dervatives as sirtuin modulators |
| JP2008540353A (ja) * | 2005-05-07 | 2008-11-20 | メリアル リミテッド | 殺虫剤用置換フェニルエーテル |
| US20070059421A1 (en) * | 2005-09-13 | 2007-03-15 | Catani Steven J | Methods and compositions to improve the palatability of foods |
| TW200800911A (en) * | 2005-10-20 | 2008-01-01 | Biolipox Ab | Pyrazoles useful in the treatment of inflammation |
| WO2007063098A1 (en) * | 2005-11-30 | 2007-06-07 | Purac Biochem Bv | Aqueous potassium lactate solution |
| WO2008024364A2 (en) * | 2006-08-22 | 2008-02-28 | Redpoint Bio Corporation | Heterocyclic compounds as sweetener enhancers |
| CN101977516B (zh) * | 2008-03-24 | 2016-12-07 | 日本水产株式会社 | 咸味增强剂及含有该咸味增强剂的饮食品 |
-
2011
- 2011-04-15 WO PCT/US2011/032782 patent/WO2011130707A2/en not_active Ceased
- 2011-04-15 JP JP2013505204A patent/JP2013523192A/ja not_active Withdrawn
- 2011-04-15 CA CA2796077A patent/CA2796077A1/en not_active Abandoned
- 2011-04-15 RU RU2012142730/13A patent/RU2597438C2/ru not_active IP Right Cessation
- 2011-04-15 US US13/641,209 patent/US20130101684A1/en not_active Abandoned
- 2011-04-15 KR KR1020127029635A patent/KR20130055601A/ko not_active Withdrawn
- 2011-04-15 EP EP11769726.8A patent/EP2558067A4/en not_active Withdrawn
- 2011-04-15 AU AU2011239447A patent/AU2011239447B2/en not_active Ceased
- 2011-04-15 CN CN201610227410.9A patent/CN105962259A/zh active Pending
- 2011-04-15 PH PH1/2012/501970A patent/PH12012501970A1/en unknown
- 2011-04-15 MX MX2012011996A patent/MX2012011996A/es unknown
- 2011-04-15 PE PE2012002026A patent/PE20130633A1/es not_active Application Discontinuation
- 2011-04-15 CN CN2011800245658A patent/CN103025313A/zh active Pending
-
2012
- 2012-10-14 IL IL222423A patent/IL222423A/en active IP Right Grant
- 2012-11-12 ZA ZA2012/08488A patent/ZA201208488B/en unknown
-
2016
- 2016-08-05 JP JP2016155087A patent/JP2017038594A/ja active Pending
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