JP2013523192A5 - - Google Patents
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- Publication number
- JP2013523192A5 JP2013523192A5 JP2013505204A JP2013505204A JP2013523192A5 JP 2013523192 A5 JP2013523192 A5 JP 2013523192A5 JP 2013505204 A JP2013505204 A JP 2013505204A JP 2013505204 A JP2013505204 A JP 2013505204A JP 2013523192 A5 JP2013523192 A5 JP 2013523192A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- slurry
- kcl
- compound
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 32
- 150000001875 compounds Chemical class 0.000 description 32
- 239000002002 slurry Substances 0.000 description 22
- 239000000243 solution Substances 0.000 description 20
- PHZLMBHDXVLRIX-UHFFFAOYSA-M potassium lactate Chemical compound [K+].CC(O)C([O-])=O PHZLMBHDXVLRIX-UHFFFAOYSA-M 0.000 description 15
- 239000001521 potassium lactate Substances 0.000 description 15
- 235000011085 potassium lactate Nutrition 0.000 description 15
- 229960001304 potassium lactate Drugs 0.000 description 15
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 239000011780 sodium chloride Substances 0.000 description 6
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 4
- 235000019658 bitter taste Nutrition 0.000 description 4
- 238000009835 boiling Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000008447 perception Effects 0.000 description 4
- 239000001540 sodium lactate Substances 0.000 description 4
- 229940005581 sodium lactate Drugs 0.000 description 4
- 235000011088 sodium lactate Nutrition 0.000 description 4
- 239000012085 test solution Substances 0.000 description 4
- 239000008156 Ringer's lactate solution Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32434610P | 2010-04-15 | 2010-04-15 | |
| US32435110P | 2010-04-15 | 2010-04-15 | |
| US32435910P | 2010-04-15 | 2010-04-15 | |
| US32434510P | 2010-04-15 | 2010-04-15 | |
| US32436210P | 2010-04-15 | 2010-04-15 | |
| US61/324,359 | 2010-04-15 | ||
| US61/324,362 | 2010-04-15 | ||
| US61/324,351 | 2010-04-15 | ||
| US61/324,346 | 2010-04-15 | ||
| US61/324,345 | 2010-04-15 | ||
| PCT/US2011/032782 WO2011130707A2 (en) | 2010-04-15 | 2011-04-15 | Compounds, compositions, and methods for reducing or eliminating bitter taste |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016155087A Division JP2017038594A (ja) | 2010-04-15 | 2016-08-05 | 苦味を低減または排除する化合物、組成物、および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013523192A JP2013523192A (ja) | 2013-06-17 |
| JP2013523192A5 true JP2013523192A5 (enExample) | 2016-11-24 |
Family
ID=44799371
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013505204A Withdrawn JP2013523192A (ja) | 2010-04-15 | 2011-04-15 | 苦味を低減または排除する化合物、組成物、および方法 |
| JP2016155087A Pending JP2017038594A (ja) | 2010-04-15 | 2016-08-05 | 苦味を低減または排除する化合物、組成物、および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016155087A Pending JP2017038594A (ja) | 2010-04-15 | 2016-08-05 | 苦味を低減または排除する化合物、組成物、および方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20130101684A1 (enExample) |
| EP (1) | EP2558067A4 (enExample) |
| JP (2) | JP2013523192A (enExample) |
| KR (1) | KR20130055601A (enExample) |
| CN (2) | CN105962259A (enExample) |
| AU (1) | AU2011239447B2 (enExample) |
| CA (1) | CA2796077A1 (enExample) |
| IL (1) | IL222423A (enExample) |
| MX (1) | MX2012011996A (enExample) |
| PE (1) | PE20130633A1 (enExample) |
| PH (1) | PH12012501970A1 (enExample) |
| RU (1) | RU2597438C2 (enExample) |
| WO (1) | WO2011130707A2 (enExample) |
| ZA (1) | ZA201208488B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6466335B2 (ja) | 2012-10-16 | 2019-02-06 | ヤンセン ファーマシューティカ エヌ．ベー． | ＲＯＲ−γ−Ｔのメチレン連結キノリニルモジュレーター |
| CN104884448A (zh) | 2012-10-16 | 2015-09-02 | 詹森药业有限公司 | Rorγt的杂芳基连接的喹啉基调节剂 |
| US9309222B2 (en) | 2012-10-16 | 2016-04-12 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
| US9221804B2 (en) | 2013-10-15 | 2015-12-29 | Janssen Pharmaceutica Nv | Secondary alcohol quinolinyl modulators of RORγt |
| US10555941B2 (en) | 2013-10-15 | 2020-02-11 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of RORγt |
| US9284308B2 (en) | 2013-10-15 | 2016-03-15 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of RORγt |
| US9403816B2 (en) | 2013-10-15 | 2016-08-02 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
| KR20160068956A (ko) | 2013-10-15 | 2016-06-15 | 얀센 파마슈티카 엔.브이. | RORyT의 퀴놀리닐 조절제 |
| CN105873439A (zh) | 2013-10-15 | 2016-08-17 | 詹森药业有限公司 | RORγt的烷基连接的喹啉基调节剂 |
| US9328095B2 (en) | 2013-10-15 | 2016-05-03 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of RORgammat |
| CN103588660B (zh) * | 2013-11-18 | 2016-06-01 | 中国医学科学院生物医学工程研究所 | 一种新型的酰基苯胺化合物及用途 |
| RU2623876C2 (ru) * | 2014-11-10 | 2017-06-29 | Александр Владимирович Диковский | Фармацевтическая композиция для лечения гиперлипидемии |
| PT3331381T (pt) * | 2015-08-07 | 2022-01-05 | V Mane Fils | Composição que compreende compostos de modulação gustativa, a sua utilização e os produtos alimentares que os compõem |
| US10413543B2 (en) * | 2015-09-01 | 2019-09-17 | Sun Pharma Advanced Research Company Ltd. | Stable multiparticulate pharmaceutical composition of rosuvastatin |
| WO2017178474A1 (en) | 2016-04-11 | 2017-10-19 | Nestec S.A. | Salt composition including sarcosine |
| JP7057287B2 (ja) * | 2016-12-28 | 2022-04-19 | 富士フイルム富山化学株式会社 | 医薬組成物 |
| CN109942537B (zh) * | 2018-03-03 | 2023-11-17 | 中国人民解放军第二军医大学 | 一类aldh2激动剂、制备方法及其用途 |
| EP3911632A1 (en) | 2019-01-15 | 2021-11-24 | Empirico Inc. | Prodrugs of alox-15 inhibitors and methods of using the same |
| US20200260761A1 (en) * | 2019-02-14 | 2020-08-20 | Stanley Weller | Compositions and Methods for Use in Food Processing and Preservation |
| CN112079777B (zh) * | 2020-08-11 | 2022-05-06 | 中山大学 | 一种多取代4-氟吖啶衍生物及其制备方法 |
| CA3213636A1 (en) | 2021-03-18 | 2022-09-22 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL45396A0 (en) * | 1973-08-23 | 1974-11-29 | Beecham Group Ltd | Pharmaceutical compositions containing aryl aralkyl ether and thioether derivatives,certain such novel compounds and their preparation |
| JPH02129171A (ja) * | 1988-11-08 | 1990-05-17 | Nissan Chem Ind Ltd | ピラゾールカルボキサニリド誘導体及び有害生物防除剤 |
| HUT68764A (en) * | 1991-11-27 | 1995-07-28 | Bioresearch Inc | Eatable taste modifiers |
| US5925527A (en) * | 1997-02-04 | 1999-07-20 | Trega Biosciences, Inc. | Tricyclic Tetrahydroquinoline derivatives and tricyclic tetrahydroquinoline combinatorial libraries |
| US6297258B1 (en) | 1998-09-29 | 2001-10-02 | American Cyanamid Company | Substituted 3-cyanoquinolines |
| MY138097A (en) | 2000-03-22 | 2009-04-30 | Du Pont | Insecticidal anthranilamides |
| US20050013835A1 (en) * | 2003-07-15 | 2005-01-20 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
| JP2007512227A (ja) * | 2003-08-06 | 2007-05-17 | セノミックス、インコーポレイテッド | Ｔ１ｒヘテロオリゴマー味覚受容体、この受容体を発現する細胞株、および味覚化合物 |
| CN101052725A (zh) * | 2003-08-06 | 2007-10-10 | 西诺米克斯公司 | T1r异寡聚味觉受体、表达所述受体的细胞系和味觉化合物 |
| DE102004041496A1 (de) * | 2004-08-27 | 2006-03-02 | Symrise Gmbh & Co. Kg | Hydroxybenzoesäureamide und deren Verwendung zur Maskierung von bitterem Geschmack |
| WO2006084184A2 (en) * | 2005-02-04 | 2006-08-10 | Senomyx, Inc. | Molecules comprising linked organic moieties as flavor modifiers for comestible compositions |
| JP4688517B2 (ja) * | 2005-02-15 | 2011-05-25 | 小川香料株式会社 | 高甘味度甘味料の呈味改善剤 |
| WO2006094237A2 (en) * | 2005-03-03 | 2006-09-08 | Sirtris Pharmaceuticals, Inc. | Acridine and quinoline dervatives as sirtuin modulators |
| EP1879454A1 (en) * | 2005-05-07 | 2008-01-23 | Merial Ltd. | Pesticidal substituted phenylethers |
| US20070059421A1 (en) * | 2005-09-13 | 2007-03-15 | Catani Steven J | Methods and compositions to improve the palatability of foods |
| TW200800911A (en) * | 2005-10-20 | 2008-01-01 | Biolipox Ab | Pyrazoles useful in the treatment of inflammation |
| EP1954148B1 (en) * | 2005-11-30 | 2016-10-05 | PURAC Biochem BV | Aqueous potassium lactate solution |
| RU2009101298A (ru) * | 2006-08-22 | 2010-09-27 | Рэдпойнт Био Корпорэйшн (Us) | Гетероциклические соединения в качестве усилителей подслащивающего вещества |
| US8932661B2 (en) * | 2008-03-24 | 2015-01-13 | Nippon Suisan Kaisha, Ltd. | Salty taste enhancer and food or drink containing same |
-
2011
- 2011-04-15 WO PCT/US2011/032782 patent/WO2011130707A2/en not_active Ceased
- 2011-04-15 RU RU2012142730/13A patent/RU2597438C2/ru not_active IP Right Cessation
- 2011-04-15 CN CN201610227410.9A patent/CN105962259A/zh active Pending
- 2011-04-15 PH PH1/2012/501970A patent/PH12012501970A1/en unknown
- 2011-04-15 CN CN2011800245658A patent/CN103025313A/zh active Pending
- 2011-04-15 US US13/641,209 patent/US20130101684A1/en not_active Abandoned
- 2011-04-15 KR KR1020127029635A patent/KR20130055601A/ko not_active Withdrawn
- 2011-04-15 AU AU2011239447A patent/AU2011239447B2/en not_active Ceased
- 2011-04-15 JP JP2013505204A patent/JP2013523192A/ja not_active Withdrawn
- 2011-04-15 CA CA2796077A patent/CA2796077A1/en not_active Abandoned
- 2011-04-15 EP EP11769726.8A patent/EP2558067A4/en not_active Withdrawn
- 2011-04-15 MX MX2012011996A patent/MX2012011996A/es unknown
- 2011-04-15 PE PE2012002026A patent/PE20130633A1/es not_active Application Discontinuation
-
2012
- 2012-10-14 IL IL222423A patent/IL222423A/en active IP Right Grant
- 2012-11-12 ZA ZA2012/08488A patent/ZA201208488B/en unknown
-
2016
- 2016-08-05 JP JP2016155087A patent/JP2017038594A/ja active Pending
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