JP2013522212A5 - - Google Patents

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Publication number
JP2013522212A5
JP2013522212A5 JP2012557185A JP2012557185A JP2013522212A5 JP 2013522212 A5 JP2013522212 A5 JP 2013522212A5 JP 2012557185 A JP2012557185 A JP 2012557185A JP 2012557185 A JP2012557185 A JP 2012557185A JP 2013522212 A5 JP2013522212 A5 JP 2013522212A5
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JP
Japan
Prior art keywords
cancer
pharmaceutical composition
mutation
leukemia
kit according
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JP2012557185A
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English (en)
Japanese (ja)
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JP2013522212A (ja
JP5827962B2 (ja
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Priority claimed from PCT/US2011/027619 external-priority patent/WO2011112635A1/en
Publication of JP2013522212A publication Critical patent/JP2013522212A/ja
Publication of JP2013522212A5 publication Critical patent/JP2013522212A5/ja
Application granted granted Critical
Publication of JP5827962B2 publication Critical patent/JP5827962B2/ja
Active legal-status Critical Current
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JP2012557185A 2010-03-08 2011-03-08 Ｃｄｃ７キナーゼ阻害剤およびその使用 Active JP5827962B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31174110P 2010-03-08 2010-03-08
US61/311,741 2010-03-08
PCT/US2011/027619 WO2011112635A1 (en) 2010-03-08 2011-03-08 Cdc7 kinase inhibitors and uses thereof

Publications (3)

Publication Number Publication Date
JP2013522212A JP2013522212A (ja) 2013-06-13
JP2013522212A5 true JP2013522212A5 (https=) 2014-08-28
JP5827962B2 JP5827962B2 (ja) 2015-12-02

Family

ID=43903897

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012557185A Active JP5827962B2 (ja) 2010-03-08 2011-03-08 Ｃｄｃ７キナーゼ阻害剤およびその使用

Country Status (11)

Country Link
US (8) US9180105B2 (https=)
EP (3) EP2544674B1 (https=)
JP (1) JP5827962B2 (https=)
CN (1) CN102844023B (https=)
AU (1) AU2011224457B2 (https=)
CA (1) CA2789484C (https=)
DK (1) DK2544674T3 (https=)
EA (1) EA025443B1 (https=)
ES (1) ES2661367T3 (https=)
TR (1) TR201800962T4 (https=)
WO (1) WO2011112635A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0406647A (pt) 2003-01-06 2005-12-06 Angiochem Inc Método para transportar um composto através da barreira sanguìnea do cérebro
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
TR201905480T4 (tr) 2008-04-18 2019-05-21 Angiochem Inc Paklitaksel, paklitaksel analogları veya paklitaksel konjugatlarının farmasötik bileşimleri ve ilgili preparasyon ve kullanım yöntemleri.
BRPI0920209A2 (pt) 2008-10-15 2015-12-22 Angiochem Inc conjugados de agonistas de glp-1 e usos dos mesmos
MX2011004019A (es) 2008-10-15 2011-06-24 Angiochem Inc Conjugados de etoposido y doxorubicina para entrega de farmacos.
CA2745524C (en) 2008-12-05 2020-06-09 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
WO2010069074A1 (en) 2008-12-17 2010-06-24 Universite Du Quebec A Montreal Membrane type-1 matrix metalloprotein inhibitors and uses thereof
WO2010121379A1 (en) 2009-04-20 2010-10-28 Angiochem Inc Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog
AU2010268726A1 (en) 2009-07-02 2012-01-19 Angiochem Inc. Multimeric peptide conjugates and uses thereof
WO2011112635A1 (en) 2010-03-08 2011-09-15 Sloan-Kettering Institute For Cancer Research Cdc7 kinase inhibitors and uses thereof
CN106659716B (zh) 2014-01-24 2021-03-12 人工智能治疗公司 阿吡莫德组合物及其使用方法
JP6569908B2 (ja) 2014-01-31 2019-09-04 カルナバイオサイエンス株式会社 抗がん剤組成物
CN103980285B (zh) * 2014-06-06 2016-03-16 中国医学科学院医药生物技术研究所 一种吡喃萘醌类抗生素及其制备和应用
US10206910B2 (en) 2014-11-07 2019-02-19 Lam Therapeutics, Inc. Apilimod for use in the treatment of renal cancer
CA2972266C (en) * 2014-12-23 2023-05-09 Sloan-Kettering Institute For Cancer Research Polymorph of granaticin b
DK3307326T3 (da) 2015-06-15 2020-10-19 Angiochem Inc Fremgangsmåder til behandling af leptomeningeal karcinomatose
KR20170054190A (ko) * 2015-11-09 2017-05-17 (주)앰틱스바이오 진균 감염 치료 및 예방을 위한 신규한 키나아제 및 이들의 용도
AU2017332839B2 (en) * 2016-09-22 2021-11-11 Cancer Research Technology Limited Preparation and uses of pyrimidinone derivatives
EP3589747B1 (en) * 2017-03-01 2021-05-19 Takeda Pharmaceutical Company Limited Method of predicting effects of cdc7 inhibitor
DK3391907T3 (da) 2017-04-20 2020-03-09 Iomx Therapeutics Ag Intracellulær kinase sik3, der er associeret med resistens over for antitumorimmunresponser, og anvendelser deraf
CN107349199A (zh) * 2017-07-18 2017-11-17 华北制药集团新药研究开发有限责任公司 榴菌素类化合物的医药用途
CN107903277B (zh) * 2017-10-18 2019-09-20 浙江大学 一种n-甲基-美达霉素类化合物及其制备方法和应用
US12139480B2 (en) 2018-04-20 2024-11-12 Iomx Therapeutics Ag 5-thiazolecarboxamide kinase inhibitor and uses thereof
GB201807147D0 (en) 2018-05-01 2018-06-13 Oncologica Uk Ltd Therapeutic combination
NL2021185B1 (en) * 2018-06-26 2020-01-06 Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis Combination Therapy and Use Thereof for Treating Cancer
EP3856352A4 (en) 2018-09-24 2022-06-29 Sierra Oncology, Inc. Methods of treatment of cancer comprising cdc7 inhibitors
JP2024511277A (ja) 2021-02-19 2024-03-13 メビオン・メディカル・システムズ・インコーポレーテッド 粒子線治療システムのためのガントリー
WO2025122699A1 (en) * 2023-12-05 2025-06-12 Lin Bioscience, Inc. Cdc7 inhibitor combinational therapy

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH476102A (de) 1966-02-22 1969-07-31 Ciba Geigy Verfahren zur Herstellung eines neuen Antibiotikums
GB1184422A (en) * 1966-02-22 1970-03-18 Ciba Ltd Antibiotic Granaticin B and Process for its Manufacture
US4270537A (en) 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4886499A (en) 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
GB8704027D0 (en) 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US5339163A (en) 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
FR2638359A1 (fr) 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5593970A (en) * 1990-06-11 1997-01-14 Biochem Pharma Inc. Heterocyclic anthracycline analogs
US5190521A (en) 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
DE4121468A1 (de) 1991-06-28 1993-01-14 Deutsches Primatenzentrum Gmbh Antivirale substanzen und diese enthaltende arzneimittel
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
SE9102652D0 (sv) 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
US5328483A (en) 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
WO1995024176A1 (en) 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
EP0932427A1 (en) 1997-07-22 1999-08-04 Emed Corporation Needle for iontophoretic delivery of agent
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
WO1999065910A1 (en) * 1998-06-16 1999-12-23 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Fused azepinone cyclin dependent kinase inhibitors
US20010047032A1 (en) 1999-12-30 2001-11-29 Castillo Gerardo M. Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases
JP4457211B2 (ja) * 2004-02-03 2010-04-28 学校法人慶應義塾 ナフトキノン誘導体化合物又はその薬理学的に許容される塩、並びに、それらを有効成分として含有するＣｄｃ２５ホスファターゼ阻害剤及び抗腫瘍剤
WO2011112635A1 (en) * 2010-03-08 2011-09-15 Sloan-Kettering Institute For Cancer Research Cdc7 kinase inhibitors and uses thereof
CA2972266C (en) 2014-12-23 2023-05-09 Sloan-Kettering Institute For Cancer Research Polymorph of granaticin b

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