JP2013521227A5 - - Google Patents
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- JP2013521227A5 JP2013521227A5 JP2012555133A JP2012555133A JP2013521227A5 JP 2013521227 A5 JP2013521227 A5 JP 2013521227A5 JP 2012555133 A JP2012555133 A JP 2012555133A JP 2012555133 A JP2012555133 A JP 2012555133A JP 2013521227 A5 JP2013521227 A5 JP 2013521227A5
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- JP
- Japan
- Prior art keywords
- substituted
- compound
- alkyl
- group
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001875 compounds Chemical class 0.000 claims description 60
- 125000000623 heterocyclic group Chemical group 0.000 claims description 40
- 125000001072 heteroaryl group Chemical group 0.000 claims description 39
- 125000004001 thioalkyl group Chemical group 0.000 claims description 38
- 125000000217 alkyl group Chemical group 0.000 claims description 37
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims description 37
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 26
- 125000000547 substituted alkyl group Chemical group 0.000 claims description 24
- 125000003342 alkenyl group Chemical group 0.000 claims description 21
- 125000000304 alkynyl group Chemical group 0.000 claims description 21
- 125000003118 aryl group Chemical group 0.000 claims description 21
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 21
- 125000002252 acyl group Chemical group 0.000 claims description 20
- 125000003545 alkoxy group Chemical group 0.000 claims description 20
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 20
- 229910052736 halogen Inorganic materials 0.000 claims description 20
- 150000002367 halogens Chemical class 0.000 claims description 20
- -1 oxazolyl-benzyl structure Chemical group 0.000 claims description 20
- 125000005254 oxyacyl group Chemical group 0.000 claims description 20
- 125000005017 substituted alkenyl group Chemical group 0.000 claims description 20
- 125000003107 substituted aryl group Chemical group 0.000 claims description 20
- 150000001408 amides Chemical class 0.000 claims description 19
- 125000005415 substituted alkoxy group Chemical group 0.000 claims description 19
- 125000004426 substituted alkynyl group Chemical group 0.000 claims description 19
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims description 18
- 125000005346 substituted cycloalkyl group Chemical group 0.000 claims description 18
- 229910052799 carbon Inorganic materials 0.000 claims description 16
- 229910052739 hydrogen Inorganic materials 0.000 claims description 14
- 241001453380 Burkholderia Species 0.000 claims description 13
- 125000003368 amide group Chemical group 0.000 claims description 12
- 125000002971 oxazolyl group Chemical group 0.000 claims description 12
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 claims description 11
- 238000004811 liquid chromatography Methods 0.000 claims description 11
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 8
- 241000607479 Yersinia pestis Species 0.000 claims description 7
- 238000004949 mass spectrometry Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 125000001424 substituent group Chemical group 0.000 claims description 7
- 229940124530 sulfonamide Drugs 0.000 claims description 7
- 150000003456 sulfonamides Chemical class 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 6
- 230000000361 pesticidal effect Effects 0.000 claims description 3
- 108020004465 16S ribosomal RNA Proteins 0.000 claims description 2
- 241000251539 Vertebrata <Metazoa> Species 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 239000004009 herbicide Substances 0.000 claims description 2
- 239000005645 nematicide Substances 0.000 claims description 2
- 230000001717 pathogenic effect Effects 0.000 claims description 2
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims 18
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 12
- 238000004128 high performance liquid chromatography Methods 0.000 claims 12
- 241000196324 Embryophyta Species 0.000 claims 7
- 150000002148 esters Chemical class 0.000 claims 6
- 230000014759 maintenance of location Effects 0.000 claims 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 6
- 229910052757 nitrogen Inorganic materials 0.000 claims 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 6
- 238000010521 absorption reaction Methods 0.000 claims 4
- 239000003905 agrochemical Substances 0.000 claims 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 4
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 4
- 229910052760 oxygen Inorganic materials 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 239000000284 extract Substances 0.000 claims 3
- 125000001041 indolyl group Chemical group 0.000 claims 3
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims 3
- 239000001301 oxygen Substances 0.000 claims 3
- 239000011347 resin Substances 0.000 claims 3
- 229920005989 resin Polymers 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 150000001733 carboxylic acid esters Chemical group 0.000 claims 2
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims 2
- 239000004744 fabric Substances 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 239000000575 pesticide Substances 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 239000006228 supernatant Substances 0.000 claims 2
- 150000003536 tetrazoles Chemical class 0.000 claims 2
- 238000000825 ultraviolet detection Methods 0.000 claims 2
- AMMUUKRRJMWLGJ-UHFFFAOYSA-N 2-(1h-indol-2-yl)-1,3-oxazole Chemical group C1=COC(C=2NC3=CC=CC=C3C=2)=N1 AMMUUKRRJMWLGJ-UHFFFAOYSA-N 0.000 claims 1
- WZRJTRPJURQBRM-UHFFFAOYSA-N 4-amino-n-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1.COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 WZRJTRPJURQBRM-UHFFFAOYSA-N 0.000 claims 1
- 241000589513 Burkholderia cepacia Species 0.000 claims 1
- 241001135516 Burkholderia gladioli Species 0.000 claims 1
- 241000020731 Burkholderia multivorans Species 0.000 claims 1
- 241001508395 Burkholderia sp. Species 0.000 claims 1
- 241000234646 Cyperaceae Species 0.000 claims 1
- DQTXAXNYLWRTPB-NTVXLVODSA-N FR901465 Chemical compound O1[C@H](C)[C@H](NC(=O)\C=C/[C@@H](OC(C)=O)C)C[C@H](C)[C@@H]1C\C=C(/C)\C=C\[C@@H]1[C@@H](O)[C@@]2(OC2)[C@@H](O)[C@@](C)(O)O1 DQTXAXNYLWRTPB-NTVXLVODSA-N 0.000 claims 1
- WKDDRNSBRWANNC-UHFFFAOYSA-N Thienamycin Natural products C1C(SCCN)=C(C(O)=O)N2C(=O)C(C(O)C)C21 WKDDRNSBRWANNC-UHFFFAOYSA-N 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 125000005907 alkyl ester group Chemical group 0.000 claims 1
- 125000003710 aryl alkyl group Chemical group 0.000 claims 1
- 125000003262 carboxylic acid ester group Chemical group [H]C([H])([*:2])OC(=O)C([H])([H])[*:1] 0.000 claims 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 claims 1
- 229960005091 chloramphenicol Drugs 0.000 claims 1
- 229960003405 ciprofloxacin Drugs 0.000 claims 1
- 239000000287 crude extract Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000007405 data analysis Methods 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 238000002330 electrospray ionisation mass spectrometry Methods 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000000417 fungicide Substances 0.000 claims 1
- ZSKVGTPCRGIANV-ZXFLCMHBSA-N imipenem Chemical compound C1C(SCC\N=C\N)=C(C(O)=O)N2C(=O)[C@H]([C@H](O)C)[C@H]21 ZSKVGTPCRGIANV-ZXFLCMHBSA-N 0.000 claims 1
- 229960002182 imipenem Drugs 0.000 claims 1
- 239000002917 insecticide Substances 0.000 claims 1
- 229930027917 kanamycin Natural products 0.000 claims 1
- 229960000318 kanamycin Drugs 0.000 claims 1
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 claims 1
- 229930182823 kanamycin A Natural products 0.000 claims 1
- 229960002292 piperacillin Drugs 0.000 claims 1
- WCMIIGXFCMNQDS-IDYPWDAWSA-M piperacillin sodium Chemical compound [Na+].O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC=CC=1)C(=O)N[C@@H]1C(=O)N2[C@@H](C([O-])=O)C(C)(C)S[C@@H]21 WCMIIGXFCMNQDS-IDYPWDAWSA-M 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000004366 reverse phase liquid chromatography Methods 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000002689 soil Substances 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 229940006995 sulfamethoxazole and trimethoprim Drugs 0.000 claims 1
- 150000003457 sulfones Chemical class 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 230000000749 insecticidal effect Effects 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 230000002363 herbicidal effect Effects 0.000 description 5
- 230000001069 nematicidal effect Effects 0.000 description 4
- 241000195493 Cryptophyta Species 0.000 description 3
- 230000000843 anti-fungal effect Effects 0.000 description 2
- 125000004104 aryloxy group Chemical group 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 239000011203 carbon fibre reinforced carbon Substances 0.000 description 2
- 125000001183 hydrocarbyl group Chemical group 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000271566 Aves Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- MZJGKTTXELXCRT-ZDUSSCGKSA-N C#[N][C@@]1(Cc2c[nH]c3ccccc23)OC(N)=NC1=O Chemical compound C#[N][C@@]1(Cc2c[nH]c3ccccc23)OC(N)=NC1=O MZJGKTTXELXCRT-ZDUSSCGKSA-N 0.000 description 1
- AOTDMJZMTYUJGS-UONOGXRCSA-N CC[C@H](C)C[C@H](C[N-2](C)C)c1nc(C(O)=O)c(-c2c[nH]c3ccccc23)[o]1 Chemical compound CC[C@H](C)C[C@H](C[N-2](C)C)c1nc(C(O)=O)c(-c2c[nH]c3ccccc23)[o]1 AOTDMJZMTYUJGS-UONOGXRCSA-N 0.000 description 1
- QWRZPVDPCWVPBI-UHFFFAOYSA-N CCc1ncc(-c2c[nH]c3ccccc23)[o]1 Chemical compound CCc1ncc(-c2c[nH]c3ccccc23)[o]1 QWRZPVDPCWVPBI-UHFFFAOYSA-N 0.000 description 1
- OUPZTQXGGFQPRA-UHFFFAOYSA-N CN(C)C(Cc1ccccc1)c1ncc(C(c2ccccc2NC=O)=O)[o]1 Chemical compound CN(C)C(Cc1ccccc1)c1ncc(C(c2ccccc2NC=O)=O)[o]1 OUPZTQXGGFQPRA-UHFFFAOYSA-N 0.000 description 1
- KHTMIJQPRGJGDE-SFHVURJKSA-N CN(CI)[C@@H](Cc1ccccc1)c1nc(O)c(C(c2c[nH]c3ccccc23)=O)[o]1 Chemical compound CN(CI)[C@@H](Cc1ccccc1)c1nc(O)c(C(c2c[nH]c3ccccc23)=O)[o]1 KHTMIJQPRGJGDE-SFHVURJKSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000890181 Haraldiophyllum Species 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241000042539 Martensia fragilis Species 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- 241000206572 Rhodophyta Species 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000003032 phytopathogenic effect Effects 0.000 description 1
- 239000001965 potato dextrose agar Substances 0.000 description 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-O sulfonium group Chemical group [SH3+] RWSOTUBLDIXVET-UHFFFAOYSA-O 0.000 description 1
- 230000003253 viricidal effect Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30828710P | 2010-02-25 | 2010-02-25 | |
| US61/308,287 | 2010-02-25 | ||
| US40654110P | 2010-10-25 | 2010-10-25 | |
| US61/406,541 | 2010-10-25 | ||
| PCT/US2011/026016 WO2011106491A2 (en) | 2010-02-25 | 2011-02-24 | Isolated bacterial strain of the genus burkholderia and pesticidal metabolites therefrom |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013521227A JP2013521227A (ja) | 2013-06-10 |
| JP2013521227A5 true JP2013521227A5 (enExample) | 2014-01-16 |
| JP5784640B2 JP5784640B2 (ja) | 2015-09-24 |
Family
ID=44476992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012555133A Active JP5784640B2 (ja) | 2010-02-25 | 2011-02-24 | バークホルデリア（Ｂｕｒｋｈｏｌｄｅｒｉａ）属の単離菌株およびそれに由来する殺虫性代謝物 |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9701673B2 (enExample) |
| EP (1) | EP2539432B1 (enExample) |
| JP (1) | JP5784640B2 (enExample) |
| KR (1) | KR101768735B1 (enExample) |
| CN (2) | CN105325460B (enExample) |
| AR (1) | AR080234A1 (enExample) |
| AU (1) | AU2011220788B2 (enExample) |
| BR (1) | BR112012021715B1 (enExample) |
| CA (1) | CA2791141C (enExample) |
| CL (1) | CL2012002354A1 (enExample) |
| CR (1) | CR20120442A (enExample) |
| DK (1) | DK2539432T3 (enExample) |
| EC (1) | ECSP12012123A (enExample) |
| ES (1) | ES2625607T3 (enExample) |
| GT (1) | GT201200249A (enExample) |
| HU (1) | HUE034377T2 (enExample) |
| IL (1) | IL221627A (enExample) |
| MA (1) | MA34018B1 (enExample) |
| MX (1) | MX2012009909A (enExample) |
| NZ (2) | NZ602434A (enExample) |
| PE (1) | PE20130558A1 (enExample) |
| PH (1) | PH12012501659B1 (enExample) |
| PL (1) | PL2539432T3 (enExample) |
| PT (1) | PT2539432T (enExample) |
| RU (1) | RU2577970C2 (enExample) |
| TN (1) | TN2012000426A1 (enExample) |
| TW (1) | TW201129318A (enExample) |
| WO (1) | WO2011106491A2 (enExample) |
| ZA (1) | ZA201206707B (enExample) |
Families Citing this family (177)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8822193B2 (en) | 2010-02-25 | 2014-09-02 | Marrone Bio Innovations, Inc. | Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom |
| US9526251B2 (en) | 2010-02-25 | 2016-12-27 | Marrone Bio Innovations, Inc. | Use of Burkholderia formulations, compositions and compounds to modulate crop yield and/or corn rootworm infestation |
| AR080234A1 (es) * | 2010-02-25 | 2012-03-21 | Marrone Bio Innovations Inc | Cepa bacteriana aislada del genero burkholderia y metabolitos pesticidas del mismo |
| NZ587490A (en) * | 2010-08-20 | 2013-03-28 | Greentide Ltd | Anti-Microbial Compounds containing compounds with a sugar substituent |
| TW201225844A (en) | 2010-10-25 | 2012-07-01 | Marrone Bio Innovations Inc | Chromobacterium bioactive compositions and metabolites |
| AU2012301466B2 (en) * | 2011-08-27 | 2015-07-23 | Marrone Bio Innovations, Inc. | Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom-formulations and uses |
| PL2770836T3 (pl) | 2011-10-25 | 2018-12-31 | Marrone Bio Innovations, Inc. | Frormulacje, kompozycje i metabolity z Chromobacterium i ich zastsowanie |
| WO2013090628A1 (en) | 2011-12-13 | 2013-06-20 | Synthetic Genomics, Inc. | Plant growth-promoting microbes and uses therefor |
| AR090316A1 (es) * | 2012-03-13 | 2014-11-05 | Marrone Bio Innovations Inc | Cepa de flavobacterium plaguicida y composiciones bioactivas, metabolitos y usos |
| US9125419B2 (en) * | 2012-08-14 | 2015-09-08 | Marrone Bio Innovations, Inc. | Bacillus sp. strain with antifungal, antibacterial and growth promotion activity |
| US9119401B2 (en) * | 2012-10-19 | 2015-09-01 | Marrone Bio Innovations, Inc. | Plant glutamine synthetase inhibitors and methods for their identification |
| ES2656298T3 (es) * | 2012-11-05 | 2018-02-26 | Pfizer Inc. | Análogos de ayustoestatina |
| WO2014102069A1 (en) * | 2012-12-31 | 2014-07-03 | Basf Se | Herbicidal composition |
| CN103149313B (zh) * | 2013-02-06 | 2014-12-03 | 中国烟草总公司四川省公司 | 一种烟草中麦草畏残留量的测定方法 |
| WO2014149241A1 (en) * | 2013-03-15 | 2014-09-25 | Marrone Bio Innovations, Inc. | Isolated bacterial strain of the genus burkholderia and pesticidal metabolites therefrom |
| WO2015034629A1 (en) * | 2013-09-07 | 2015-03-12 | Marrone Bio Innovations, Inc. | Methods and compositions for control of mite infestations using a newly discovered species of burkholderia |
| CA2931111C (en) | 2013-11-19 | 2022-03-15 | Purdue Research Foundation | Anti-cancer agents and preparation thereof |
| CA2957803A1 (en) | 2014-09-11 | 2016-03-17 | Marrone Bio Innovations, Inc. | Chromobacterium subtsugae genome |
| CN107530350A (zh) | 2014-12-11 | 2018-01-02 | 哈佛理事会 | 细胞坏死抑制剂及相关方法 |
| CN105319313B (zh) * | 2015-12-09 | 2017-02-01 | 山东出入境检验检疫局检验检疫技术中心 | 一种毒黄素的液相色谱‑串联质谱检测方法 |
| CN105368953A (zh) * | 2015-12-10 | 2016-03-02 | 山东出入境检验检疫局检验检疫技术中心 | 唐菖蒲伯克霍尔德菌的实时荧光pcr检测试剂盒和方法 |
| US11051518B2 (en) * | 2016-06-27 | 2021-07-06 | Korea Research Institute Of Bioscience And Biotechnology | Pseudozyma churashimaensis strain RGJ1 isolated from pepper plant and use thereof |
| WO2018168582A1 (ja) * | 2017-03-14 | 2018-09-20 | イビデン株式会社 | 殺虫剤および殺虫剤の製造方法 |
| BR112020002697A2 (pt) * | 2017-09-08 | 2020-07-28 | Marrone Bio Innovations, Inc. | composto herbicida |
| CN107988100B (zh) * | 2017-12-05 | 2021-06-22 | 湖南豫园生物科技股份有限公司 | 无机解磷菌、微生物肥料及应用 |
| CN108739860B (zh) * | 2018-05-02 | 2020-10-23 | 华南农业大学 | 一种微生物群体感应信号淬灭菌及其作为生防菌的应用 |
| WO2020127364A1 (en) * | 2018-12-18 | 2020-06-25 | Futureco Bioscience, S.A. | Microbacterium esteraromaticum strain, composition comprising the same, and uses thereof |
| CN111349089B (zh) * | 2018-12-24 | 2022-11-29 | 天津师范大学 | 一类吲哚杂环化合物及其制备方法和在防治植物病害中的应用 |
| CN111349088B (zh) * | 2018-12-24 | 2022-09-20 | 天津师范大学 | 基于吲哚的杂环化合物及其制备方法和在防治植物病害中的应用 |
| EP3902908A4 (en) * | 2018-12-24 | 2024-01-03 | Pro Farm Group, Inc. | A method for increasing romidepsin production from fermentation broth |
| CN109750077A (zh) * | 2019-01-15 | 2019-05-14 | 华南农业大学 | 杜比亚蟑螂共生真菌活性次生代谢产物的制备方法及用途 |
| EP3701796A1 (en) | 2019-08-08 | 2020-09-02 | Bayer AG | Active compound combinations |
| CN110656141B (zh) * | 2019-10-14 | 2023-01-13 | 陕西麦可罗生物科技有限公司 | 一种三七黑斑病防治用多抗霉素的发酵工艺 |
| CN110699290B (zh) * | 2019-11-01 | 2021-01-05 | 华东师范大学 | 一种稳定伯克霍尔德氏菌、菌剂及其制备方法和应用 |
| EP4061131A1 (en) | 2019-11-18 | 2022-09-28 | Bayer Aktiengesellschaft | Active compound combinations comprising fatty acids |
| CN110699305B (zh) * | 2019-11-27 | 2023-01-13 | 云南大学 | 一种伯克氏菌及其该伯克氏菌的应用 |
| CN110771631B (zh) * | 2019-12-10 | 2021-03-26 | 云南大学 | 一种利用复合杀线虫微生物防治线虫病害的方法 |
| EP3708565A1 (en) | 2020-03-04 | 2020-09-16 | Bayer AG | Pyrimidinyloxyphenylamidines and the use thereof as fungicides |
| WO2021209490A1 (en) | 2020-04-16 | 2021-10-21 | Bayer Aktiengesellschaft | Cyclaminephenylaminoquinolines as fungicides |
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