JP2013519411A5 - - Google Patents

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JP2013519411A5
JP2013519411A5 JP2012552462A JP2012552462A JP2013519411A5 JP 2013519411 A5 JP2013519411 A5 JP 2013519411A5 JP 2012552462 A JP2012552462 A JP 2012552462A JP 2012552462 A JP2012552462 A JP 2012552462A JP 2013519411 A5 JP2013519411 A5 JP 2013519411A5
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Japan
Prior art keywords
implantable fluid
fluid router
gas
outlet
liquid
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JP2012552462A
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JP2013519411A (ja
JP5826191B2 (ja
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Priority claimed from GBGB1002370.3A external-priority patent/GB201002370D0/en
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好ましくは、流体ルーターのそれぞれの気体排出口は、チャンバーを含む。有利なことに、それぞれのチャンバーは、フィルターチャンバーを通ってルート決定される流体中に存在する気体が通過し得る気体透過性膜を含む。好ましくは、気体透過性膜は疎水性である。気体透過性膜は、延伸ポリテトラフルオロエチレン(polytetraflurothylene)(ePTFE)を含み得る。また、それぞれのチャンバーは、液体がフィルターチャンバーを通ってルート決定される際に通過する親水性物質を含み得る。該親水性材料は、好ましくは、細菌保持性であるので細菌フィルターとしても作用する。このように、流体ルーターは、気体フィルターおよび細菌フィルターの両方として働く。1つ以上の流入口から1つ以上の流出口へとルート決定される液体が治療剤を含むことが好ましい。治療剤は、埋め込まれたポンプから、または(体の)外部ポンプから供給され得る。好ましい態様において、流体は、経皮アクセスデバイスを介して流体ルーターへと供給される。
図10を参照すると、埋め込み可能直線型気泡フィルターデバイスが図示される。該デバイスは、流入口900、流出口902、親水性(細菌保持)膜904および延伸ポリテトラフルオロエチレン(ePTFE)で作製された外部気体透過性(疎水性)膜906を含む。ePTFEは、細胞が成長しないかまたはそれに接着しないように処理され得るというさらなる利点を有する。示さないが、外部保護メッシュが施されてもよい。該デバイスは、埋め込み可能薬物送達システムの一部として含まれ得る。

Claims (15)

1つ以上の流入口、1つ以上の流出口および該1つ以上の流入口から該1つ以上の流出口へとルート決定された液体から気体を除去するための少なくとも1つの気体排出口を含む埋め込み可能流体ルーター。
複数の流入口、複数の流出口および該複数の流入口と該複数の流出口の間の複数の別々の流路を含む、請求項１記載の埋め込み可能流体ルーター。
複数の気体排出口を含み、ここで、それぞれの流路が別々の気体排出口を含む、請求項２記載の埋め込み可能流体ルーター。
1つの流入口、1つの流出口および該流入口と該流出口の間の流路中に1つの気体排出口を含む、請求項１記載の埋め込み可能流体ルーター。
カテーテルヘッドの形態で提供される、請求項４記載の埋め込み可能流体ルーター。
それぞれの気体排出口が、デバイスが埋め込まれた被験体の体内に気体を排出するように配置された、請求項１〜５いずれか記載の埋め込み可能流体ルーター。
それぞれの気体排出口がチャンバーを含む、請求項１〜６いずれか記載の埋め込み可能流体ルーター。
それぞれのチャンバーが、フィルターチャンバーを通ってルート決定された液体中に存在する気体が通過し得る、気体透過性膜を含む、請求項７記載の埋め込み可能流体ルーター。
気体透過性膜が疎水性である、請求項８記載の埋め込み可能流体ルーター。
気体透過性膜が、延伸ポリテトラフルオロエチレン(polytetraflurothylene) (ePTFE)を含む、請求項８または９記載の埋め込み可能流体ルーター。
それぞれのチャンバーが、液体がフィルターチャンバーを通ってルート決定される場合に該液体が通過する親水性材料を含む、請求項７〜１０いずれか記載の埋め込み可能流体ルーター。
親水性材料が細菌保持性であり、それにより細菌フィルターとしても作用する、請求項１１記載の埋め込み可能流体ルーター。
1つ以上の流入口から1つ以上の流出口へとルート決定された液体が治療剤を含む、請求項１〜１２いずれか記載の埋め込み可能流体ルーター。
請求項１〜１３いずれか記載の埋め込み可能流体ルーターを含む、神経外科カテーテル。
請求項１〜１３いずれか記載の埋め込み可能流体ルーター、ならびに
神経外科カテーテル、供給チューブおよび経皮アクセスデバイスの少なくとも1つ
を含む、神経外科キット。
JP2012552462A 2010-02-12 2011-02-11 埋め込み可能流体ルーター Expired - Fee Related JP5826191B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1002370.3 2010-02-12
GBGB1002370.3A GB201002370D0 (en) 2010-02-12 2010-02-12 Percutaneous drug delivery apparatus
PCT/GB2011/000182 WO2011098768A1 (en) 2010-02-12 2011-02-11 Implantable fluid router

Publications (3)

Publication Number Publication Date
JP2013519411A JP2013519411A (ja) 2013-05-30
JP2013519411A5 true JP2013519411A5 (ja) 2014-03-27
JP5826191B2 JP5826191B2 (ja) 2015-12-02

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JP2012552462A Expired - Fee Related JP5826191B2 (ja) 2010-02-12 2011-02-11 埋め込み可能流体ルーター
JP2012552463A Active JP5801323B2 (ja) 2010-02-12 2011-02-11 経皮薬物送達装置
JP2015166782A Active JP6151320B2 (ja) 2010-02-12 2015-08-26 経皮薬物送達装置

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JP2012552463A Active JP5801323B2 (ja) 2010-02-12 2011-02-11 経皮薬物送達装置
JP2015166782A Active JP6151320B2 (ja) 2010-02-12 2015-08-26 経皮薬物送達装置

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US (4) US10507316B2 (ja)
EP (3) EP3900758A1 (ja)
JP (3) JP5826191B2 (ja)
CN (4) CN105288782B (ja)
ES (1) ES2864579T3 (ja)
GB (1) GB201002370D0 (ja)
WO (2) WO2011098769A1 (ja)

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