JP2013518640A - 時間鎖錠を備えた薬用モジュール - Google Patents
時間鎖錠を備えた薬用モジュール Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/3245—Constructional features thereof, e.g. to improve manipulation or functioning
- A61M2005/3247—Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
- A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3294—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
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- Vascular Medicine (AREA)
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Abstract
【選択図】 図2
Description
一度、モジュールが使用され取り除かれた時点で一次薬物送達デバイスへの薬用モジュール再取り付けの物理的阻止。
一度、それが使用された時点での薬物投与インターフェイスを通した以後の液体流の物理的/水圧的阻止。
一次薬物送達デバイスの用量セッター及び/又は用量ボタンの物理的ロック。
視覚的警告(例えばいったん挿入及び/又は流体流が生じた時のモジュールに関する表示窓内の色及び/又は匂い及び/又は警告文/表示物(indicia)の変化)。
触覚フィードバック(使用後のモジュールハブの外面における触覚特性の存在又は不存在)。
1 内側ハウジング
2 第2の薬剤
3 針
4 薬用モジュール
5 ばね
6 トリガ
7 薬物送達デバイス
8 取り付け手段
9 連結手段
10 外側ハウジング
11 ガスオリフィス
12 用量セッター
13 用量ボタン
14 ダンパ
15 ばね
16 ニードルガード
17 コンパートメント
18 コンパートメント
19 弁
20 チャンネル
22 バイパスチャンネル
23 ニードルカニューレ
24 チャンネル
25 ヒステリシス材料
31 リザーバ
32 遠位端
100 スロットプロファイル
101 突出部
102 ランプ
103 タブ
104 停止機能
105 ガードロック/回転ロック
106 ランプ機能
107 ランプ機能
110 遠位方向
111 後退
112 回転運動
Claims (17)
- 少なくとも1つのニードルカニューレ(3)に対して保護を提供するように適合及び配置され、注射部位に適用中軸方向に動くように構成される、ニードルガード(16);及び
所定時間の経過後にニードルガード(16)の動きを阻止するように適合及び配置され、ニードルガード(16)に操作可能に連結される、時間鎖錠組立体;
を含んでなる、薬物送達デバイス(7)とともに使用するための時間制御ロッキング機構。 - 起動されたガードロック(105)は、ニードルガード(16)が遠位に完全に伸びているとき、ニードルガード(16)が軸方向に動くことを防止するガードロック(105)を更に含んでなる、請求項1に記載の時間制御ロッキング機構。
- 時間鎖錠組立体は、第1の位置から第2の位置まで可動であるダンパ(14)を含み、ダンパ(14)が第2の位置にありそしてニードルガード(16)が遠位に完全に伸びているとき、ダンパ(14)がガードロック(105)を起動するように適合及び配置される、請求項2に記載の時間制御ロッキング機構。
- 所定時間内に第1の位置から第2の位置までダンパ(14)を動かすように構成される手段を含んでなる、請求項3に記載の時間制御ロッキング機構。
- 前記手段は気体オリフィス(11)又はヒステリシス部材(25)を含む、請求項4に記載の時間制御ロッキング機構。
- 薬物送達デバイス(7)が第1の薬剤の一次リザーバを含んでなり、そして薬用モジュール(4)が第2の薬剤(2)を含んでなる、薬物送達デバイス(7)に取り付け可能な薬用モジュール(4)であって、ここで薬用モジュール(4)は第2の薬剤(2)の少なくとも1つの用量を保持するように適合及び配置されるリザーバ(31)を含み、そして薬用モジュールは請求項1〜5のいずれか1項に記載の時間制御ロッキング機構を含む、上記薬用モジュール(4)。
- 薬用モジュール(4)が薬物送達デバイス(7)に取り付けられた後、ニードルガード(16)が最初に後退したときに始まる所定時間経過後に、ニードルガード(16)が軸方向に動くことを防止する、請求項6に記載の薬用モジュール(4)。
- ニードルガード(16)及びリザーバ(31)に操作可能に連結され、そして薬用モジュール(4)のリザーバ(31)と一次リザーバの流体連通を可能にするように構成される弁(19)を含んでなる、請求項6又は7に記載の薬用モジュール(4)。
- リザーバ(31)がハウジング(1、10)中に配置され、そしてニードルガード(16)がハウジング(1、10)に操作可能に連結される、薬物送達デバイス(7)への取り付け用に構成されるハウジング(1、10)を含んでなる、請求項6〜8のいずれか1項に記載の薬用モジュール(4)。
- ハウジング(1、10)は遠位端及び近位端を含み、そして薬用モジュール(4)は第2のニードルカニューレ(23)を含み、第2のニードルカニューレ(23)が近位端に取り付けられそして第1のニードルカニューレ(3)がハウジング(1、10)の遠位端に取り付けられる、請求項9に記載の薬用モジュール(4)。
- ニードルガード(16)が遠位方向に完全に伸びているとき、2つのニードルカニューレ(3、23)は第2の薬剤(2)との流体連通になく、そしてニードルガード(16)が近位方向に後退したとき、2つのニードルカニューレ(3、23)は第2の薬剤(2)と流体連通する、請求項10に記載の薬用モジュール(4)。
- 弁(19)は、薬用モジュール(4)のリザーバ(31)と一次リザーバの流体連通を可能にするために回転するように構成される回転弁である、請求項8〜11のいずれか1項に記載の薬用モジュール(4)。
- リザーバ(31)がリザーバ(31)をバイパスするように適合及び配置されるバイパス(22)を有する、請求項6〜12のいずれか1項に記載の薬用モジュール(4)。
- ニードルガード(16)が遠位方向に完全に伸びているとき、弁(19)はバイパス(22)とニードルカニューレ(3、23)の流体連通を可能にするように構成される、請求項13に記載の薬用モジュール(4)。
- a. 少なくとも1つの薬剤を含む第1の薬剤の一次リザーバを含んでなるハウジング、
b.薬用モジュール(4)が一次リザーバと流体連通するように構成される、請求項6〜14のいずれか1項に記載の薬用モジュール(4)を含んでなる、2つ又はそれ以上の薬剤を送達する薬物送達デバイス(7)。 - ハウジングへの薬用モジュール(4)の連結及び近位方向におけるニードルガード(16)の後退が時間鎖錠をトリガする、請求項15に記載の薬物送達デバイス(7)。
- ハウジングへの薬用モジュール(4)の連結及びニードルガード(16)の後退が弁(19)を作動させる、請求項15又は16に記載の薬物送達デバイス(7)。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
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US30170010P | 2010-02-05 | 2010-02-05 | |
US61/301,700 | 2010-02-05 | ||
EP10160842 | 2010-04-23 | ||
EP10160842.0 | 2010-04-23 | ||
PCT/EP2011/051401 WO2011095483A1 (en) | 2010-02-05 | 2011-02-01 | Medicated module with time lock |
Publications (2)
Publication Number | Publication Date |
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JP2013518640A true JP2013518640A (ja) | 2013-05-23 |
JP5770748B2 JP5770748B2 (ja) | 2015-08-26 |
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Application Number | Title | Priority Date | Filing Date |
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JP2012551597A Expired - Fee Related JP5770748B2 (ja) | 2010-02-05 | 2011-02-01 | 時間鎖錠を備えた薬用モジュール |
Country Status (9)
Country | Link |
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US (1) | US20130018310A1 (ja) |
EP (1) | EP2531237A1 (ja) |
JP (1) | JP5770748B2 (ja) |
CN (1) | CN102753222B (ja) |
AU (1) | AU2011212561B2 (ja) |
BR (1) | BR112012019658A2 (ja) |
CA (1) | CA2788648A1 (ja) |
IL (1) | IL221136A (ja) |
WO (1) | WO2011095483A1 (ja) |
Cited By (1)
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JP2017525469A (ja) * | 2014-08-18 | 2017-09-07 | ウィンドギャップ メディカル, インコーポレイテッド | 携帯型薬剤混合及び送達装置並びに関連の方法 |
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PT2822618T (pt) | 2012-03-06 | 2024-03-04 | Antares Pharma Inc | Seringa pré-cheia com característica de força de rutura |
EP3549524B1 (en) | 2012-03-30 | 2023-01-25 | Insulet Corporation | Fluid delivery device with transcutaneous access tool, insertion mechanism and blood glucose monitoring for use therewith |
CA2868500C (en) | 2012-04-06 | 2020-04-21 | Antares Pharma, Inc. | Needle assisted jet injection administration of testosterone compositions |
US9364611B2 (en) | 2012-05-07 | 2016-06-14 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
US11007327B2 (en) | 2012-10-25 | 2021-05-18 | Novo Nordisk A/S | Pre-filled disposable injection device |
EP2934625A1 (en) * | 2012-12-19 | 2015-10-28 | Novo Nordisk A/S | A needle device |
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Also Published As
Publication number | Publication date |
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CN102753222A (zh) | 2012-10-24 |
JP5770748B2 (ja) | 2015-08-26 |
IL221136A (en) | 2015-07-30 |
BR112012019658A2 (pt) | 2016-05-03 |
CN102753222B (zh) | 2015-01-07 |
EP2531237A1 (en) | 2012-12-12 |
US20130018310A1 (en) | 2013-01-17 |
CA2788648A1 (en) | 2011-08-11 |
AU2011212561B2 (en) | 2014-11-20 |
AU2011212561A1 (en) | 2012-08-16 |
WO2011095483A1 (en) | 2011-08-11 |
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