JP2013516479A5 - - Google Patents

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Publication number
JP2013516479A5
JP2013516479A5 JP2012548125A JP2012548125A JP2013516479A5 JP 2013516479 A5 JP2013516479 A5 JP 2013516479A5 JP 2012548125 A JP2012548125 A JP 2012548125A JP 2012548125 A JP2012548125 A JP 2012548125A JP 2013516479 A5 JP2013516479 A5 JP 2013516479A5
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JP
Japan
Prior art keywords
unsaturated bond
contain
branched
lower alkyl
oxygen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012548125A
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English (en)
Japanese (ja)
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JP2013516479A (ja
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Publication date
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Priority claimed from PCT/US2011/020414 external-priority patent/WO2011085126A2/en
Publication of JP2013516479A publication Critical patent/JP2013516479A/ja
Publication of JP2013516479A5 publication Critical patent/JP2013516479A5/ja
Pending legal-status Critical Current

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JP2012548125A 2010-01-06 2011-01-06 標的薬物を開発する方法および組成物 Pending JP2013516479A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29277610P 2010-01-06 2010-01-06
US61/292,776 2010-01-06
PCT/US2011/020414 WO2011085126A2 (en) 2010-01-06 2011-01-06 Methods and compositions of targeted drug development

Publications (2)

Publication Number Publication Date
JP2013516479A JP2013516479A (ja) 2013-05-13
JP2013516479A5 true JP2013516479A5 (https=) 2014-11-06

Family

ID=44306150

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012548125A Pending JP2013516479A (ja) 2010-01-06 2011-01-06 標的薬物を開発する方法および組成物

Country Status (10)

Country Link
US (4) US8618302B2 (https=)
EP (2) EP2521553A4 (https=)
JP (1) JP2013516479A (https=)
KR (1) KR20130027080A (https=)
CN (1) CN102811723A (https=)
AU (1) AU2011204368B2 (https=)
CA (2) CA2786289A1 (https=)
MX (1) MX2012007872A (https=)
SG (1) SG182343A1 (https=)
WO (2) WO2011085126A2 (https=)

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JP2014527511A (ja) 2011-06-24 2014-10-16 アムジエン・インコーポレーテツド Ｔｒｐｍ８拮抗剤及び治療におけるそれらの使用
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AU2013262476A1 (en) * 2012-05-18 2014-12-04 Georgetown University Populating and searching a drug informatics database
WO2013192423A2 (en) 2012-06-20 2013-12-27 Eutropics Pharmaceuticals, Inc. Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors
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US10732182B2 (en) 2013-08-01 2020-08-04 Eutropics Pharmaceuticals, Inc. Method for predicting cancer sensitivity
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JP6538044B2 (ja) 2013-10-30 2019-07-03 ユートロピクス ファーマシューティカルズ， インコーポレイテッド 化学療法感受性および化学毒性を判定する方法
CN104016908B (zh) * 2014-04-03 2016-04-20 定陶县友帮化工有限公司 一种2-氨基-3，5-二氯吡啶的合成方法
CN104402831B (zh) * 2014-10-24 2016-08-17 郑州大学 含酰脲结构单元的-5-氰基嘧啶衍生物及其制备方法和用途
CN104744439A (zh) * 2015-02-10 2015-07-01 南开大学 8-羟基喹啉类ntr1小分子拮抗剂及应用
HUP1500098A2 (hu) * 2015-03-09 2016-09-28 Avidin Kft 8-hidroxikinolin származékok új enantiomerjei és szintézisük
US10624881B2 (en) * 2015-10-12 2020-04-21 Health Research, Inc. Methods for inducing apoptosis in cancer cells
EP3388419A1 (en) * 2017-04-12 2018-10-17 Leadiant Biosciences SA Gli1 inhibitors and uses thereof
WO2019043635A1 (en) 2017-09-01 2019-03-07 Richter Gedeon Nyrt. COMPOUNDS INHIBITING THE ACTIVITY OF D-AMINO ACID OXIDASE
JP7636322B2 (ja) * 2018-11-15 2025-02-26 アンスティテュ・ギュスターヴ・ルシー 癌を処置するためのマドラシン誘導体化合物、組成物およびこれらの使用
TW202218665A (zh) 2020-09-21 2022-05-16 德國阿爾伯特路德維希弗萊堡大學 用於治療或預防造血細胞移植後血液科贅瘤(neoplasm)復發之mdm2抑制劑
CN112250637A (zh) * 2020-10-30 2021-01-22 中山大学 虚拟筛选的化合物在制备抗肿瘤药物中的应用及其药物
CN117645560A (zh) * 2021-12-16 2024-03-05 贵州大学 一种含酰胺的阿魏酸衍生物及其制备方法和应用
WO2024073624A2 (en) * 2022-09-28 2024-04-04 The Research Foundation For The State University Of New York Antiproliferative betti bases and prodrugs thereof
CN115572266B (zh) * 2022-10-24 2023-10-03 南方医科大学 一种蛋白抑制剂、一种试剂组及其应用
CN120463779B (zh) * 2025-07-10 2025-09-19 南京农业大学三亚研究院 真菌效应子药靶Nep1及基于该药靶的高通量药物分子筛选和应用

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