JP2013516429A5 - - Google Patents
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- JP2013516429A5 JP2013516429A5 JP2012547311A JP2012547311A JP2013516429A5 JP 2013516429 A5 JP2013516429 A5 JP 2013516429A5 JP 2012547311 A JP2012547311 A JP 2012547311A JP 2012547311 A JP2012547311 A JP 2012547311A JP 2013516429 A5 JP2013516429 A5 JP 2013516429A5
- Authority
- JP
- Japan
- Prior art keywords
- bbi
- protein
- soy
- subjecting
- impurities
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims description 26
- 238000000926 separation method Methods 0.000 claims description 21
- 239000000047 product Substances 0.000 claims description 19
- 239000012535 impurity Substances 0.000 claims description 14
- 108010073771 Soybean Proteins Proteins 0.000 claims description 12
- 229940001941 soy protein Drugs 0.000 claims description 12
- 238000013375 chromatographic separation Methods 0.000 claims description 10
- 108090000623 proteins and genes Proteins 0.000 claims description 8
- 102000004169 proteins and genes Human genes 0.000 claims description 8
- 239000012466 permeate Substances 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 4
- 238000001556 precipitation Methods 0.000 claims description 3
- 239000003599 detergent Substances 0.000 claims description 2
- 235000010469 Glycine max Nutrition 0.000 description 8
- 239000012528 membrane Substances 0.000 description 7
- 238000005342 ion exchange Methods 0.000 description 4
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 238000004255 ion exchange chromatography Methods 0.000 description 2
- 239000003456 ion exchange resin Substances 0.000 description 2
- 229920003303 ion-exchange polymer Polymers 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 1
- 238000005377 adsorption chromatography Methods 0.000 description 1
- 238000001042 affinity chromatography Methods 0.000 description 1
- 239000003957 anion exchange resin Substances 0.000 description 1
- 239000003729 cation exchange resin Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000001471 micro-filtration Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000004366 reverse phase liquid chromatography Methods 0.000 description 1
- 238000001542 size-exclusion chromatography Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29131209P | 2009-12-30 | 2009-12-30 | |
| US61/291,312 | 2009-12-30 | ||
| PCT/US2010/062556 WO2011082338A1 (en) | 2009-12-30 | 2010-12-30 | Method for recovering bowman-birk inhibitor proteins from a soy processing stream |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013516429A JP2013516429A (ja) | 2013-05-13 |
| JP2013516429A5 true JP2013516429A5 (enExample) | 2014-02-13 |
Family
ID=44226820
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547316A Pending JP2013516431A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
| JP2012547309A Pending JP2013516427A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製ボーマン・バークプロテアーゼインヒビタープロテイン |
| JP2012547311A Pending JP2013516429A (ja) | 2009-12-30 | 2010-12-30 | ボーマン・バークインヒビタープロテインを大豆加工ストリームから回収する方法 |
| JP2012547317A Pending JP2013516432A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームからＫｕｎｉｔｚトリプシンインヒビタータンパク質を回収する方法 |
| JP2015118467A Abandoned JP2015157873A (ja) | 2009-12-30 | 2015-06-11 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547316A Pending JP2013516431A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
| JP2012547309A Pending JP2013516427A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製ボーマン・バークプロテアーゼインヒビタープロテイン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547317A Pending JP2013516432A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームからＫｕｎｉｔｚトリプシンインヒビタータンパク質を回収する方法 |
| JP2015118467A Abandoned JP2015157873A (ja) | 2009-12-30 | 2015-06-11 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20120329993A1 (enExample) |
| EP (5) | EP2519535A4 (enExample) |
| JP (5) | JP2013516431A (enExample) |
| CN (6) | CN102781255B (enExample) |
| BR (2) | BR112012016232A2 (enExample) |
| CA (2) | CA2785599A1 (enExample) |
| WO (5) | WO2011082359A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3083198A1 (en) | 2008-03-26 | 2009-10-01 | Oramed Ltd. | Methods and compositions for oral administration of proteins |
| EP2725912A4 (en) * | 2011-06-29 | 2015-03-04 | Solae Llc | BAKERY COMPOSITIONS WITH SOYAMOL PROTEINS ISOLATED FROM PROCESSING STREAMS |
| WO2013114369A1 (en) * | 2012-02-01 | 2013-08-08 | Oramed Ltd | Protease inhibitor-containing compositions, compositions comprising same, and methods for producing and using same |
| EP2877040A1 (en) * | 2012-07-26 | 2015-06-03 | Solae, LLC | Emulsifying agent for use in food compositions |
| CN104768426A (zh) * | 2012-07-26 | 2015-07-08 | 索莱有限责任公司 | 用于个人护理产品和工业产品中的发泡剂 |
| BR112015001566A2 (pt) * | 2012-07-26 | 2017-07-04 | Dupont Nutrition Biosci Aps | agente de formação de espuma, produto alimentício, método para a fabricação de um produto alimentício e agente de formação de espuma estabilizado. |
| CN104902960A (zh) * | 2012-07-26 | 2015-09-09 | 索莱有限责任公司 | 用于个人护理产品和工业产品中的乳化剂 |
| EP2912052A1 (en) | 2012-10-23 | 2015-09-02 | Upfront Chromatography A/S | Separation processes for soy protein |
| JP2016505613A (ja) | 2013-01-03 | 2016-02-25 | オラムド エルティーディー． | Ｎａｆｌｄ、脂肪肝、および、その後遺症を処置するための方法および組成物 |
| FR3001362B1 (fr) | 2013-01-31 | 2015-07-10 | Roquette Freres | Procede de fractionnement des solubles de pois, fractions obtenues et leur valorisation |
| CN103392907B (zh) * | 2013-06-08 | 2014-12-17 | 东北农业大学 | 酶法修饰改善乳清蛋白纳米纤维聚合量的方法 |
| WO2015101435A1 (en) * | 2013-12-30 | 2015-07-09 | Koninklijke Philips N.V. | A method of making soymilk |
| UA117778C2 (uk) | 2014-01-29 | 2018-09-25 | Апфронт Кроматоґрафі А/С | Спосіб розділення горохового білка |
| CN103933548A (zh) * | 2014-04-17 | 2014-07-23 | 中国药科大学 | 露那辛多肽在防治白内障药物中的应用 |
| CN108697116A (zh) | 2015-10-30 | 2018-10-23 | 贝丝以色列女执事医疗中心 | 用于测定谷物、面粉、植物和复合食品中的谷物淀粉酶胰蛋白酶抑制剂的生物活性、量、除去或失活的方法 |
| US10858390B2 (en) * | 2016-09-02 | 2020-12-08 | Cem Corporation | Use of excess carbodiimide for peptide synthesis at elevated temperatures |
| EP3599881A4 (en) | 2017-03-31 | 2021-02-17 | J.R. Simplot Company | POTATO PROTEIN POWDERS |
| CN107488226A (zh) * | 2017-09-06 | 2017-12-19 | 成都晟博源生物工程有限公司 | 一种大豆胰蛋白酶抑制剂的提取方法 |
| CN110872140B (zh) * | 2018-09-03 | 2022-06-21 | 中国石油化工股份有限公司 | 危化品分离回收系统 |
| CN110104754B (zh) * | 2019-04-03 | 2022-03-29 | 江苏农林职业技术学院 | 一种豆制品废水废渣处理甲基橙染料废水的方法 |
| CN110551209A (zh) * | 2019-08-27 | 2019-12-10 | 合肥天汇孵化科技有限公司 | 一种基于大豆深加工废液以豆清水为原料粗提sbti蛋白工艺 |
| WO2021099529A1 (en) * | 2019-11-20 | 2021-05-27 | Csl Behring Ag | Method for extracting a protein from a precipitate and method for precipitating impurities |
| BR112022016879A2 (pt) * | 2020-02-26 | 2022-12-06 | Eat Just Inc | Isolamento de proteína de grãos de leguminosa através da ultrafiltração |
| JP2023528657A (ja) * | 2020-06-12 | 2023-07-05 | ビーエーエスエフ ソシエタス・ヨーロピア | 発酵ブロスの改善された脱塩及び例えばオリゴ糖のファインケミカルの精製 |
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| US4368151A (en) * | 1981-08-10 | 1983-01-11 | A. E. Staley Manufacturing Company | 7S And 11S vegetable protein fractionation and isolation |
| US5288856A (en) * | 1986-11-20 | 1994-02-22 | Pierre Amiguet | Method of isolating acid-stable, biologically active proteins |
| US4808314A (en) * | 1987-09-18 | 1989-02-28 | Scripps Clinic And Research Foundation | Method for reducing bacterial endotoxin contamination in solutions of macromolecules |
| US5250515A (en) * | 1988-04-11 | 1993-10-05 | Monsanto Company | Method for improving the efficacy of insect toxins |
| TR24186A (tr) * | 1988-04-11 | 1991-05-30 | Monsanto Co | Hasere zehirlerinin etkinligini arttirmak icin yoentem |
| JPH06145198A (ja) * | 1992-03-30 | 1994-05-24 | Shokuhin Sangyo High Separeeshiyon Syst Gijutsu Kenkyu Kumiai | 大豆トリプシンインヒビターの製造方法 |
| DK46793D0 (da) * | 1993-04-26 | 1993-04-26 | Novo Nordisk As | Enzym |
| JPH1066572A (ja) * | 1996-08-29 | 1998-03-10 | Showa Sangyo Co Ltd | 高純度の大豆トリプシンインヒビターの製造方法 |
| US6313273B1 (en) * | 1999-08-25 | 2001-11-06 | Abbott Laboratories | Soy proteins and methods for their production |
| US6787173B2 (en) * | 2000-11-30 | 2004-09-07 | Kraft Foods Holdings, Inc. | Method of deflavoring soy-derived materials |
| US7175869B2 (en) * | 2000-11-30 | 2007-02-13 | Kraft Foods Holdings, Inc. | Method of deflavoring soy-derived materials using electrodialysis |
| CN1150831C (zh) * | 2001-01-19 | 2004-05-26 | 北京中联捷思科技发展有限公司 | 超滤提取大豆乳清蛋白的方法 |
| US6927322B2 (en) * | 2001-03-30 | 2005-08-09 | Cornell Research Foundation, Inc. | Cabbage proteinase inhibitor gene confers resistance against plant pests |
| US7214394B2 (en) * | 2002-05-31 | 2007-05-08 | Archer-Daniels-Midland Company | Policosanol compositions, extraction from novel sources, and uses thereof |
| CN100506062C (zh) * | 2002-08-28 | 2009-07-01 | 不二制油株式会社 | 酸性大豆蛋白质凝胶食物及其生产方法 |
| WO2004104036A1 (ja) * | 2003-05-21 | 2004-12-02 | Fuji Oil Company, Limited | 大豆ホエー蛋白及び大豆ホエー蛋白分解物の製造法 |
| US20070277269A1 (en) * | 2006-04-17 | 2007-11-29 | Ceres, Inc. | Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics |
| JP2007510431A (ja) * | 2003-11-05 | 2007-04-26 | ケリー グループ サーヴィシーズ インターナショナル、リミテッド | 酸安定大豆タンパク及び強化食品又は飲料 |
| EP1689766B1 (en) * | 2003-11-06 | 2012-04-25 | Danisco US Inc. | Expression in filamentous fungi of protease inhibitors and variants thereof |
| EP1692159B1 (en) * | 2003-11-06 | 2010-09-29 | Danisco US Inc. | Tgf-beta1 binding and supported peptides |
| CN1615722A (zh) * | 2003-11-14 | 2005-05-18 | 哈高科大豆食品有限责任公司 | 超滤膜分离技术制备大豆分离蛋白的方法 |
| KR20060133585A (ko) * | 2004-02-26 | 2006-12-26 | 후지 세이유 가부시키가이샤 | 대두 단백질 함유 용액 내지 겔 |
| JP4912875B2 (ja) * | 2004-02-27 | 2012-04-11 | 不二製油株式会社 | 癌転移抑制組成物 |
| US20060057275A1 (en) * | 2004-09-16 | 2006-03-16 | Shaowen Wu | Process for the preparation of glycinin-rich and beta-conglycinin-rich protein fractions |
| EP1880007A2 (en) * | 2005-05-05 | 2008-01-23 | Genencor International, Inc. | Personal care compositions and methods for their use |
| US20070054031A1 (en) * | 2005-09-02 | 2007-03-08 | Keshun Liu | Methods of extracting, concentrating and fractionating proteins and other chemical components |
| TWI257723B (en) * | 2005-09-15 | 2006-07-01 | Epitech Technology Corp | Vertical light-emitting diode and method for manufacturing the same |
| US20080182002A1 (en) * | 2007-01-26 | 2008-07-31 | Solae, Llc | Processes for Removing Bitter Components from Soy Protein Isolates |
| BRPI0811788A2 (pt) * | 2007-07-03 | 2014-10-07 | Solae Llc | Composição de proteína vegetal, processo para a fabricação de uma composição de proteína vegetal e produto alimentício |
| CN101367018A (zh) * | 2007-09-13 | 2009-02-18 | 中国海洋大学 | 壳聚糖树脂固定化酶纯化大豆乳清废水中胰蛋白酶抑制剂的工艺 |
| CN102245635B (zh) * | 2008-10-15 | 2016-08-31 | 丹尼斯科美国公司 | 修饰的变体bowman birk蛋白酶抑制剂 |
-
2010
- 2010-12-30 WO PCT/US2010/062592 patent/WO2011082359A1/en not_active Ceased
- 2010-12-30 US US13/519,829 patent/US20120329993A1/en not_active Abandoned
- 2010-12-30 CA CA2785599A patent/CA2785599A1/en not_active Abandoned
- 2010-12-30 US US13/519,848 patent/US20120289683A1/en not_active Abandoned
- 2010-12-30 CN CN201080064855.0A patent/CN102781255B/zh not_active Expired - Fee Related
- 2010-12-30 WO PCT/US2010/062553 patent/WO2011082335A2/en not_active Ceased
- 2010-12-30 WO PCT/US2010/062591 patent/WO2011082358A1/en not_active Ceased
- 2010-12-30 US US13/519,832 patent/US20130023480A1/en not_active Abandoned
- 2010-12-30 US US13/519,840 patent/US20120302736A1/en not_active Abandoned
- 2010-12-30 WO PCT/US2010/062556 patent/WO2011082338A1/en not_active Ceased
- 2010-12-30 US US13/519,842 patent/US20130023649A1/en not_active Abandoned
- 2010-12-30 EP EP10841743.7A patent/EP2519535A4/en not_active Withdrawn
- 2010-12-30 EP EP10841760.1A patent/EP2785730A1/en not_active Withdrawn
- 2010-12-30 JP JP2012547316A patent/JP2013516431A/ja active Pending
- 2010-12-30 BR BR112012016232A patent/BR112012016232A2/pt not_active IP Right Cessation
- 2010-12-30 EP EP10841740.3A patent/EP2519251A4/en not_active Withdrawn
- 2010-12-30 JP JP2012547309A patent/JP2013516427A/ja active Pending
- 2010-12-30 CN CN201410168443.1A patent/CN103988973A/zh active Pending
- 2010-12-30 CN CN2010800648368A patent/CN102770439A/zh active Pending
- 2010-12-30 BR BR112012016225A patent/BR112012016225A2/pt active Search and Examination
- 2010-12-30 CA CA2785736A patent/CA2785736A1/en not_active Abandoned
- 2010-12-30 JP JP2012547311A patent/JP2013516429A/ja active Pending
- 2010-12-30 JP JP2012547317A patent/JP2013516432A/ja active Pending
- 2010-12-30 EP EP10841758.5A patent/EP2519117A4/en not_active Withdrawn
- 2010-12-30 CN CN2010800642291A patent/CN102770147A/zh active Pending
- 2010-12-30 WO PCT/US2010/062594 patent/WO2011082360A1/en not_active Ceased
- 2010-12-30 CN CN2010800648423A patent/CN102781459A/zh active Pending
- 2010-12-30 EP EP10841759.3A patent/EP2519245A4/en not_active Withdrawn
- 2010-12-30 CN CN201080064208XA patent/CN102762584A/zh active Pending
-
2015
- 2015-06-11 JP JP2015118467A patent/JP2015157873A/ja not_active Abandoned
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