JP2013516429A5 - - Google Patents
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- Publication number
- JP2013516429A5 JP2013516429A5 JP2012547311A JP2012547311A JP2013516429A5 JP 2013516429 A5 JP2013516429 A5 JP 2013516429A5 JP 2012547311 A JP2012547311 A JP 2012547311A JP 2012547311 A JP2012547311 A JP 2012547311A JP 2013516429 A5 JP2013516429 A5 JP 2013516429A5
- Authority
- JP
- Japan
- Prior art keywords
- bbi
- protein
- soy
- subjecting
- impurities
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims description 26
- 238000000926 separation method Methods 0.000 claims description 21
- 239000000047 product Substances 0.000 claims description 19
- 239000012535 impurity Substances 0.000 claims description 14
- 108010073771 Soybean Proteins Proteins 0.000 claims description 12
- 229940001941 soy protein Drugs 0.000 claims description 12
- 238000013375 chromatographic separation Methods 0.000 claims description 10
- 108090000623 proteins and genes Proteins 0.000 claims description 8
- 102000004169 proteins and genes Human genes 0.000 claims description 8
- 239000012466 permeate Substances 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 4
- 238000001556 precipitation Methods 0.000 claims description 3
- 239000003599 detergent Substances 0.000 claims description 2
- 235000010469 Glycine max Nutrition 0.000 description 8
- 239000012528 membrane Substances 0.000 description 7
- 238000005342 ion exchange Methods 0.000 description 4
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 238000004255 ion exchange chromatography Methods 0.000 description 2
- 239000003456 ion exchange resin Substances 0.000 description 2
- 229920003303 ion-exchange polymer Polymers 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 1
- 238000005377 adsorption chromatography Methods 0.000 description 1
- 238000001042 affinity chromatography Methods 0.000 description 1
- 239000003957 anion exchange resin Substances 0.000 description 1
- 239000003729 cation exchange resin Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000001471 micro-filtration Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000004366 reverse phase liquid chromatography Methods 0.000 description 1
- 238000001542 size-exclusion chromatography Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29131209P | 2009-12-30 | 2009-12-30 | |
| US61/291,312 | 2009-12-30 | ||
| PCT/US2010/062556 WO2011082338A1 (en) | 2009-12-30 | 2010-12-30 | Method for recovering bowman-birk inhibitor proteins from a soy processing stream |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013516429A JP2013516429A (ja) | 2013-05-13 |
| JP2013516429A5 true JP2013516429A5 (enExample) | 2014-02-13 |
Family
ID=44226820
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547316A Pending JP2013516431A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
| JP2012547309A Pending JP2013516427A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製ボーマン・バークプロテアーゼインヒビタープロテイン |
| JP2012547311A Pending JP2013516429A (ja) | 2009-12-30 | 2010-12-30 | ボーマン・バークインヒビタープロテインを大豆加工ストリームから回収する方法 |
| JP2012547317A Pending JP2013516432A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームからＫｕｎｉｔｚトリプシンインヒビタータンパク質を回収する方法 |
| JP2015118467A Abandoned JP2015157873A (ja) | 2009-12-30 | 2015-06-11 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547316A Pending JP2013516431A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
| JP2012547309A Pending JP2013516427A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製ボーマン・バークプロテアーゼインヒビタープロテイン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547317A Pending JP2013516432A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームからＫｕｎｉｔｚトリプシンインヒビタータンパク質を回収する方法 |
| JP2015118467A Abandoned JP2015157873A (ja) | 2009-12-30 | 2015-06-11 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20130023649A1 (enExample) |
| EP (5) | EP2785730A1 (enExample) |
| JP (5) | JP2013516431A (enExample) |
| CN (6) | CN103988973A (enExample) |
| BR (2) | BR112012016232A2 (enExample) |
| CA (2) | CA2785736A1 (enExample) |
| WO (5) | WO2011082359A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ588603A (en) | 2008-03-26 | 2012-03-30 | Oramed Ltd | Methods and compositions for oral administration of a protein of up to 100000 Daltaons, a first protease inhibitor and a second protease inhibitor wherein said protease inhibitors inhibit trypsin |
| EP2725912A4 (en) * | 2011-06-29 | 2015-03-04 | Solae Llc | BAKERY COMPOSITIONS WITH SOYAMOL PROTEINS ISOLATED FROM PROCESSING STREAMS |
| WO2013114369A1 (en) * | 2012-02-01 | 2013-08-08 | Oramed Ltd | Protease inhibitor-containing compositions, compositions comprising same, and methods for producing and using same |
| BR112015001581A2 (pt) * | 2012-07-26 | 2017-07-04 | Solae Llc | agente de emulsificação, produto para os cuidados pessoais, produto industrial, equipamento, método para a fabricação de um produto e agente de emulsificação de estabilização |
| CN104736001A (zh) * | 2012-07-26 | 2015-06-24 | 索莱有限责任公司 | 用于食品组合物中的发泡剂 |
| WO2014018922A1 (en) * | 2012-07-26 | 2014-01-30 | Solae, Llc | Emulsifying agent for use in food compositions |
| US20150246332A1 (en) * | 2012-07-26 | 2015-09-03 | Solac, LLC | Foaming agent for use in industrial products |
| US9765111B2 (en) | 2012-10-23 | 2017-09-19 | Upfront Chromatography A/S | Separation processes for soy protein |
| WO2014106846A2 (en) | 2013-01-03 | 2014-07-10 | Oramed Ltd. | Methods and compositions for treating nafld, hepatic steatosis, and sequelae thereof |
| FR3001362B1 (fr) | 2013-01-31 | 2015-07-10 | Roquette Freres | Procede de fractionnement des solubles de pois, fractions obtenues et leur valorisation |
| CN103392907B (zh) * | 2013-06-08 | 2014-12-17 | 东北农业大学 | 酶法修饰改善乳清蛋白纳米纤维聚合量的方法 |
| WO2015101435A1 (en) * | 2013-12-30 | 2015-07-09 | Koninklijke Philips N.V. | A method of making soymilk |
| CA2937598A1 (en) * | 2014-01-29 | 2015-08-06 | Upfront Chromatography A/S | Novel separation processes for pea protein |
| CN103933548A (zh) * | 2014-04-17 | 2014-07-23 | 中国药科大学 | 露那辛多肽在防治白内障药物中的应用 |
| AU2016343738B2 (en) * | 2015-10-30 | 2021-05-13 | Beth Israel Deaconess Medical Center, Inc. | Methods for determination of bioactivity, quantity, removal, or inactivation of cereal amylase trypsin inhibitors in cereals, flours, plants, and complex foods |
| US10858390B2 (en) * | 2016-09-02 | 2020-12-08 | Cem Corporation | Use of excess carbodiimide for peptide synthesis at elevated temperatures |
| AU2018243407B2 (en) | 2017-03-31 | 2024-04-04 | J.R. Simplot Company | Potato protein powders |
| CN107488226A (zh) * | 2017-09-06 | 2017-12-19 | 成都晟博源生物工程有限公司 | 一种大豆胰蛋白酶抑制剂的提取方法 |
| CN110872140B (zh) * | 2018-09-03 | 2022-06-21 | 中国石油化工股份有限公司 | 危化品分离回收系统 |
| CN110104754B (zh) * | 2019-04-03 | 2022-03-29 | 江苏农林职业技术学院 | 一种豆制品废水废渣处理甲基橙染料废水的方法 |
| CN110551209A (zh) * | 2019-08-27 | 2019-12-10 | 合肥天汇孵化科技有限公司 | 一种基于大豆深加工废液以豆清水为原料粗提sbti蛋白工艺 |
| US20230002444A1 (en) * | 2019-11-20 | 2023-01-05 | Csl Behring Ag | Method for extracting a protein from a precipitate and method for precipitating impurities |
| JP2023515828A (ja) * | 2020-02-26 | 2023-04-14 | イート ジャスト， インコーポレイテッド | 限外濾過によるパルスタンパク質単離 |
| EP4165057A1 (en) * | 2020-06-12 | 2023-04-19 | Basf Se | Improved demineralization of fermentation broths and purification of fine chemicals such as oligosaccharides |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4368151A (en) * | 1981-08-10 | 1983-01-11 | A. E. Staley Manufacturing Company | 7S And 11S vegetable protein fractionation and isolation |
| US5288856A (en) * | 1986-11-20 | 1994-02-22 | Pierre Amiguet | Method of isolating acid-stable, biologically active proteins |
| US4808314A (en) * | 1987-09-18 | 1989-02-28 | Scripps Clinic And Research Foundation | Method for reducing bacterial endotoxin contamination in solutions of macromolecules |
| US5250515A (en) * | 1988-04-11 | 1993-10-05 | Monsanto Company | Method for improving the efficacy of insect toxins |
| TR24186A (tr) * | 1988-04-11 | 1991-05-30 | Monsanto Co | Hasere zehirlerinin etkinligini arttirmak icin yoentem |
| JPH06145198A (ja) * | 1992-03-30 | 1994-05-24 | Shokuhin Sangyo High Separeeshiyon Syst Gijutsu Kenkyu Kumiai | 大豆トリプシンインヒビターの製造方法 |
| DK46793D0 (da) * | 1993-04-26 | 1993-04-26 | Novo Nordisk As | Enzym |
| JPH1066572A (ja) * | 1996-08-29 | 1998-03-10 | Showa Sangyo Co Ltd | 高純度の大豆トリプシンインヒビターの製造方法 |
| US6313273B1 (en) * | 1999-08-25 | 2001-11-06 | Abbott Laboratories | Soy proteins and methods for their production |
| US7175869B2 (en) * | 2000-11-30 | 2007-02-13 | Kraft Foods Holdings, Inc. | Method of deflavoring soy-derived materials using electrodialysis |
| US6787173B2 (en) * | 2000-11-30 | 2004-09-07 | Kraft Foods Holdings, Inc. | Method of deflavoring soy-derived materials |
| CN1150831C (zh) * | 2001-01-19 | 2004-05-26 | 北京中联捷思科技发展有限公司 | 超滤提取大豆乳清蛋白的方法 |
| US6927322B2 (en) * | 2001-03-30 | 2005-08-09 | Cornell Research Foundation, Inc. | Cabbage proteinase inhibitor gene confers resistance against plant pests |
| US7214394B2 (en) * | 2002-05-31 | 2007-05-08 | Archer-Daniels-Midland Company | Policosanol compositions, extraction from novel sources, and uses thereof |
| CN100506062C (zh) * | 2002-08-28 | 2009-07-01 | 不二制油株式会社 | 酸性大豆蛋白质凝胶食物及其生产方法 |
| JPWO2004104036A1 (ja) * | 2003-05-21 | 2006-10-26 | 不二製油株式会社 | 大豆ホエー蛋白及び大豆ホエー蛋白分解物の製造法 |
| US20070277269A1 (en) * | 2006-04-17 | 2007-11-29 | Ceres, Inc. | Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics |
| CA2544898A1 (en) * | 2003-11-05 | 2005-05-19 | Kerry Group Services International, Ltd. | Acid-stable soy protein and fortified food or beverage |
| DK1680507T3 (da) * | 2003-11-06 | 2011-10-10 | Danisco Us Inc | Bakterieekspression af proteaseinhibitorer og varianter deraf |
| ATE555119T1 (de) * | 2003-11-06 | 2012-05-15 | Danisco Us Inc | Expression von proteaseinhibitoren und varianten davon in filamentösen pilzen |
| CN1615722A (zh) * | 2003-11-14 | 2005-05-18 | 哈高科大豆食品有限责任公司 | 超滤膜分离技术制备大豆分离蛋白的方法 |
| US20090269456A1 (en) * | 2004-02-26 | 2009-10-29 | Toshio Kiriyama | Soybean protein-containing solution and gel |
| EP1731160B1 (en) * | 2004-02-27 | 2012-07-11 | Fuji Oil Company, Ltd. | Cancer metastasis inhibitory composition |
| US20060057275A1 (en) * | 2004-09-16 | 2006-03-16 | Shaowen Wu | Process for the preparation of glycinin-rich and beta-conglycinin-rich protein fractions |
| BRPI0613548A2 (pt) * | 2005-05-05 | 2011-01-18 | Genencor Int | composições de cuidado pessoal e métodos para seu uso |
| US20070054031A1 (en) * | 2005-09-02 | 2007-03-08 | Keshun Liu | Methods of extracting, concentrating and fractionating proteins and other chemical components |
| TWI257723B (en) * | 2005-09-15 | 2006-07-01 | Epitech Technology Corp | Vertical light-emitting diode and method for manufacturing the same |
| US20080182002A1 (en) * | 2007-01-26 | 2008-07-31 | Solae, Llc | Processes for Removing Bitter Components from Soy Protein Isolates |
| US20090011083A1 (en) * | 2007-07-03 | 2009-01-08 | Solae, Llc | Modified Vegetable Protein Having Low Levels of Phytic Acid, Isoflavones and Ash |
| CN101367018A (zh) * | 2007-09-13 | 2009-02-18 | 中国海洋大学 | 壳聚糖树脂固定化酶纯化大豆乳清废水中胰蛋白酶抑制剂的工艺 |
| AU2008362898B2 (en) * | 2008-10-15 | 2013-02-28 | Danisco Us Inc. | Modified variant Bowman Birk Protease inhibitors |
-
2010
- 2010-12-30 WO PCT/US2010/062592 patent/WO2011082359A1/en not_active Ceased
- 2010-12-30 WO PCT/US2010/062556 patent/WO2011082338A1/en not_active Ceased
- 2010-12-30 US US13/519,842 patent/US20130023649A1/en not_active Abandoned
- 2010-12-30 JP JP2012547316A patent/JP2013516431A/ja active Pending
- 2010-12-30 WO PCT/US2010/062591 patent/WO2011082358A1/en not_active Ceased
- 2010-12-30 US US13/519,829 patent/US20120329993A1/en not_active Abandoned
- 2010-12-30 JP JP2012547309A patent/JP2013516427A/ja active Pending
- 2010-12-30 US US13/519,848 patent/US20120289683A1/en not_active Abandoned
- 2010-12-30 WO PCT/US2010/062594 patent/WO2011082360A1/en not_active Ceased
- 2010-12-30 JP JP2012547311A patent/JP2013516429A/ja active Pending
- 2010-12-30 EP EP10841760.1A patent/EP2785730A1/en not_active Withdrawn
- 2010-12-30 CN CN201410168443.1A patent/CN103988973A/zh active Pending
- 2010-12-30 WO PCT/US2010/062553 patent/WO2011082335A2/en not_active Ceased
- 2010-12-30 CN CN201080064208XA patent/CN102762584A/zh active Pending
- 2010-12-30 CA CA2785736A patent/CA2785736A1/en not_active Abandoned
- 2010-12-30 CN CN2010800648423A patent/CN102781459A/zh active Pending
- 2010-12-30 US US13/519,840 patent/US20120302736A1/en not_active Abandoned
- 2010-12-30 JP JP2012547317A patent/JP2013516432A/ja active Pending
- 2010-12-30 EP EP10841743.7A patent/EP2519535A4/en not_active Withdrawn
- 2010-12-30 CN CN2010800648368A patent/CN102770439A/zh active Pending
- 2010-12-30 EP EP10841740.3A patent/EP2519251A4/en not_active Withdrawn
- 2010-12-30 US US13/519,832 patent/US20130023480A1/en not_active Abandoned
- 2010-12-30 CA CA2785599A patent/CA2785599A1/en not_active Abandoned
- 2010-12-30 EP EP10841759.3A patent/EP2519245A4/en not_active Withdrawn
- 2010-12-30 BR BR112012016232A patent/BR112012016232A2/pt not_active IP Right Cessation
- 2010-12-30 BR BR112012016225A patent/BR112012016225A2/pt active Search and Examination
- 2010-12-30 CN CN201080064855.0A patent/CN102781255B/zh not_active Expired - Fee Related
- 2010-12-30 EP EP10841758.5A patent/EP2519117A4/en not_active Withdrawn
- 2010-12-30 CN CN2010800642291A patent/CN102770147A/zh active Pending
-
2015
- 2015-06-11 JP JP2015118467A patent/JP2015157873A/ja not_active Abandoned
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