JP2013516427A5 - - Google Patents
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- JP2013516427A5 JP2013516427A5 JP2012547309A JP2012547309A JP2013516427A5 JP 2013516427 A5 JP2013516427 A5 JP 2013516427A5 JP 2012547309 A JP2012547309 A JP 2012547309A JP 2012547309 A JP2012547309 A JP 2012547309A JP 2013516427 A5 JP2013516427 A5 JP 2013516427A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- bbi
- protein
- product
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims description 27
- 108090000623 proteins and genes Proteins 0.000 claims description 27
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 22
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 12
- 230000000694 effects Effects 0.000 claims description 10
- 230000002401 inhibitory effect Effects 0.000 claims description 10
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 claims description 9
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims description 9
- 239000002158 endotoxin Substances 0.000 claims description 8
- 108090000317 Chymotrypsin Proteins 0.000 claims description 5
- 101710137926 Chymotrypsin inhibitor Proteins 0.000 claims description 5
- 108090000631 Trypsin Proteins 0.000 claims description 5
- 102000004142 Trypsin Human genes 0.000 claims description 5
- 229940122618 Trypsin inhibitor Drugs 0.000 claims description 5
- 101710162629 Trypsin inhibitor Proteins 0.000 claims description 5
- 229960002376 chymotrypsin Drugs 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 239000012588 trypsin Substances 0.000 claims description 5
- 239000002753 trypsin inhibitor Substances 0.000 claims description 5
- 229940122644 Chymotrypsin inhibitor Drugs 0.000 claims description 4
- 239000003541 chymotrypsin inhibitor Substances 0.000 claims description 4
- 230000001575 pathological effect Effects 0.000 claims description 3
- 230000001737 promoting effect Effects 0.000 claims description 2
- 230000036559 skin health Effects 0.000 claims description 2
- 108091005804 Peptidases Proteins 0.000 claims 1
- 239000004365 Protease Substances 0.000 claims 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
- 229940121649 protein inhibitor Drugs 0.000 claims 1
- 239000012268 protein inhibitor Substances 0.000 claims 1
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29131209P | 2009-12-30 | 2009-12-30 | |
| US61/291,312 | 2009-12-30 | ||
| PCT/US2010/062553 WO2011082335A2 (en) | 2009-12-30 | 2010-12-30 | Purified bowman-birk protease inhibitor proteins isolated from a soy processing stream |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013516427A JP2013516427A (ja) | 2013-05-13 |
| JP2013516427A5 true JP2013516427A5 (https=) | 2014-02-13 |
Family
ID=44226820
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547316A Pending JP2013516431A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
| JP2012547309A Pending JP2013516427A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製ボーマン・バークプロテアーゼインヒビタープロテイン |
| JP2012547311A Pending JP2013516429A (ja) | 2009-12-30 | 2010-12-30 | ボーマン・バークインヒビタープロテインを大豆加工ストリームから回収する方法 |
| JP2012547317A Pending JP2013516432A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームからＫｕｎｉｔｚトリプシンインヒビタータンパク質を回収する方法 |
| JP2015118467A Abandoned JP2015157873A (ja) | 2009-12-30 | 2015-06-11 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547316A Pending JP2013516431A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547311A Pending JP2013516429A (ja) | 2009-12-30 | 2010-12-30 | ボーマン・バークインヒビタープロテインを大豆加工ストリームから回収する方法 |
| JP2012547317A Pending JP2013516432A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームからＫｕｎｉｔｚトリプシンインヒビタータンパク質を回収する方法 |
| JP2015118467A Abandoned JP2015157873A (ja) | 2009-12-30 | 2015-06-11 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20120329993A1 (https=) |
| EP (5) | EP2519245A4 (https=) |
| JP (5) | JP2013516431A (https=) |
| CN (6) | CN102770147A (https=) |
| BR (2) | BR112012016232A2 (https=) |
| CA (2) | CA2785599A1 (https=) |
| WO (5) | WO2011082338A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ588603A (en) | 2008-03-26 | 2012-03-30 | Oramed Ltd | Methods and compositions for oral administration of a protein of up to 100000 Daltaons, a first protease inhibitor and a second protease inhibitor wherein said protease inhibitors inhibit trypsin |
| WO2013002786A1 (en) * | 2011-06-29 | 2013-01-03 | Solae | Baked food compositions comprising soy whey proteins that have been isolated from processing streams |
| JP6567827B2 (ja) * | 2012-02-01 | 2019-08-28 | オラムド エルティーディー． | プロテアーゼ阻害剤を含有する組成物、該組成物を含む組成物、および、該組成物を製造および使用する方法 |
| JP2015528703A (ja) * | 2012-07-26 | 2015-10-01 | ソレイ リミテッド ライアビリティ カンパニー | 食品組成物で使用するための発泡剤 |
| JP2015533100A (ja) * | 2012-07-26 | 2015-11-19 | ソレイ リミテッド ライアビリティ カンパニー | パーソナルケア製品および工業製品で使用するための発泡剤 |
| EP2877040A1 (en) * | 2012-07-26 | 2015-06-03 | Solae, LLC | Emulsifying agent for use in food compositions |
| WO2014018923A2 (en) * | 2012-07-26 | 2014-01-30 | Solae, Llc | Emulsifying agent for use in personal care products and industrial products |
| EP2912052A1 (en) | 2012-10-23 | 2015-09-02 | Upfront Chromatography A/S | Separation processes for soy protein |
| CN104902921A (zh) | 2013-01-03 | 2015-09-09 | 奥拉姆德有限公司 | 用于治疗nafld、肝性脂肪变性及其后遗症的方法和组合物 |
| FR3001362B1 (fr) | 2013-01-31 | 2015-07-10 | Roquette Freres | Procede de fractionnement des solubles de pois, fractions obtenues et leur valorisation |
| CN103392907B (zh) * | 2013-06-08 | 2014-12-17 | 东北农业大学 | 酶法修饰改善乳清蛋白纳米纤维聚合量的方法 |
| WO2015101435A1 (en) * | 2013-12-30 | 2015-07-09 | Koninklijke Philips N.V. | A method of making soymilk |
| US10457704B2 (en) | 2014-01-29 | 2019-10-29 | Upfront Chromatography A/S | Separation processes for pea protein |
| CN103933548A (zh) * | 2014-04-17 | 2014-07-23 | 中国药科大学 | 露那辛多肽在防治白内障药物中的应用 |
| US11291221B2 (en) | 2015-10-30 | 2022-04-05 | Beth Israel Deaconess Medical Center, Inc. | Methods for determination of bioactivity, quantity, removal, or inactivation of cereal amylase trypsin inhibitors in cereals, flours, plants, and complex foods |
| US10858390B2 (en) * | 2016-09-02 | 2020-12-08 | Cem Corporation | Use of excess carbodiimide for peptide synthesis at elevated temperatures |
| CA3055986C (en) | 2017-03-31 | 2025-09-16 | J.R. Simplot Company | POTATO PROTEIN POWDERS |
| CN107488226A (zh) * | 2017-09-06 | 2017-12-19 | 成都晟博源生物工程有限公司 | 一种大豆胰蛋白酶抑制剂的提取方法 |
| CN110872140B (zh) * | 2018-09-03 | 2022-06-21 | 中国石油化工股份有限公司 | 危化品分离回收系统 |
| CN110104754B (zh) * | 2019-04-03 | 2022-03-29 | 江苏农林职业技术学院 | 一种豆制品废水废渣处理甲基橙染料废水的方法 |
| CN118909100A (zh) * | 2019-08-27 | 2024-11-08 | 合肥天汇生物科技有限公司 | 一种基于大豆深加工废液以豆清水为原料粗提sbti蛋白工艺 |
| EP4061826A1 (en) * | 2019-11-20 | 2022-09-28 | CSL Behring AG | Method for extracting a protein from a precipitate and method for precipitating impurities |
| AU2021227964A1 (en) * | 2020-02-26 | 2022-09-22 | Eat Just, Inc. | Pulse protein isolation by ultrafiltration |
| WO2021250191A1 (en) * | 2020-06-12 | 2021-12-16 | Basf Se | Improved demineralization of fermentation broths and purification of fine chemicals such as oligosaccharides |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4368151A (en) * | 1981-08-10 | 1983-01-11 | A. E. Staley Manufacturing Company | 7S And 11S vegetable protein fractionation and isolation |
| US5288856A (en) * | 1986-11-20 | 1994-02-22 | Pierre Amiguet | Method of isolating acid-stable, biologically active proteins |
| US4808314A (en) * | 1987-09-18 | 1989-02-28 | Scripps Clinic And Research Foundation | Method for reducing bacterial endotoxin contamination in solutions of macromolecules |
| US5250515A (en) * | 1988-04-11 | 1993-10-05 | Monsanto Company | Method for improving the efficacy of insect toxins |
| TR24186A (tr) * | 1988-04-11 | 1991-05-30 | Monsanto Co | Hasere zehirlerinin etkinligini arttirmak icin yoentem |
| JPH06145198A (ja) * | 1992-03-30 | 1994-05-24 | Shokuhin Sangyo High Separeeshiyon Syst Gijutsu Kenkyu Kumiai | 大豆トリプシンインヒビターの製造方法 |
| DK46793D0 (da) * | 1993-04-26 | 1993-04-26 | Novo Nordisk As | Enzym |
| JPH1066572A (ja) * | 1996-08-29 | 1998-03-10 | Showa Sangyo Co Ltd | 高純度の大豆トリプシンインヒビターの製造方法 |
| US6313273B1 (en) * | 1999-08-25 | 2001-11-06 | Abbott Laboratories | Soy proteins and methods for their production |
| US7175869B2 (en) * | 2000-11-30 | 2007-02-13 | Kraft Foods Holdings, Inc. | Method of deflavoring soy-derived materials using electrodialysis |
| US6787173B2 (en) * | 2000-11-30 | 2004-09-07 | Kraft Foods Holdings, Inc. | Method of deflavoring soy-derived materials |
| CN1150831C (zh) * | 2001-01-19 | 2004-05-26 | 北京中联捷思科技发展有限公司 | 超滤提取大豆乳清蛋白的方法 |
| US6927322B2 (en) * | 2001-03-30 | 2005-08-09 | Cornell Research Foundation, Inc. | Cabbage proteinase inhibitor gene confers resistance against plant pests |
| US7214394B2 (en) * | 2002-05-31 | 2007-05-08 | Archer-Daniels-Midland Company | Policosanol compositions, extraction from novel sources, and uses thereof |
| CN100506062C (zh) * | 2002-08-28 | 2009-07-01 | 不二制油株式会社 | 酸性大豆蛋白质凝胶食物及其生产方法 |
| WO2004104036A1 (ja) * | 2003-05-21 | 2004-12-02 | Fuji Oil Company, Limited | 大豆ホエー蛋白及び大豆ホエー蛋白分解物の製造法 |
| US20070277269A1 (en) * | 2006-04-17 | 2007-11-29 | Ceres, Inc. | Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics |
| BRPI0416231A (pt) * | 2003-11-05 | 2007-01-02 | Kerry Group Services Internati | proteìnas de soja estáveis em ácido solúveis na água, bebida acìdica, produto alimentìcio acìdico e métodos de fortalecimento de bebida acìdica com proteìna de soja, de preparação de proteìna de soja estável em ácido solúvel em água e de preparação de alimento ou bebida |
| DE602004029393D1 (de) * | 2003-11-06 | 2010-11-11 | Danisco Us Inc | Tgf-beta1-bindende und geträgerte peptide |
| KR101348530B1 (ko) * | 2003-11-06 | 2014-02-14 | 다니스코 유에스 인크. | 프로테아제 저해자 및 그 변이체의 사상균 내에서의 발현 |
| CN1615722A (zh) * | 2003-11-14 | 2005-05-18 | 哈高科大豆食品有限责任公司 | 超滤膜分离技术制备大豆分离蛋白的方法 |
| KR20060133585A (ko) * | 2004-02-26 | 2006-12-26 | 후지 세이유 가부시키가이샤 | 대두 단백질 함유 용액 내지 겔 |
| JP4912875B2 (ja) * | 2004-02-27 | 2012-04-11 | 不二製油株式会社 | 癌転移抑制組成物 |
| US20060057275A1 (en) * | 2004-09-16 | 2006-03-16 | Shaowen Wu | Process for the preparation of glycinin-rich and beta-conglycinin-rich protein fractions |
| BRPI0613548A2 (pt) * | 2005-05-05 | 2011-01-18 | Genencor Int | composições de cuidado pessoal e métodos para seu uso |
| US20070054031A1 (en) * | 2005-09-02 | 2007-03-08 | Keshun Liu | Methods of extracting, concentrating and fractionating proteins and other chemical components |
| TWI257723B (en) * | 2005-09-15 | 2006-07-01 | Epitech Technology Corp | Vertical light-emitting diode and method for manufacturing the same |
| US20080182002A1 (en) * | 2007-01-26 | 2008-07-31 | Solae, Llc | Processes for Removing Bitter Components from Soy Protein Isolates |
| WO2009006597A1 (en) * | 2007-07-03 | 2009-01-08 | Solae, Llc | Modified vegetable protein having low levels of phytic acid, isoflavones, and ash |
| CN101367018A (zh) * | 2007-09-13 | 2009-02-18 | 中国海洋大学 | 壳聚糖树脂固定化酶纯化大豆乳清废水中胰蛋白酶抑制剂的工艺 |
| BRPI0823193A2 (pt) * | 2008-10-15 | 2019-09-24 | Danisco Us Inc | inibidores de protease de bowman birk variantes modificados |
-
2010
- 2010-12-30 EP EP10841759.3A patent/EP2519245A4/en not_active Withdrawn
- 2010-12-30 CN CN2010800642291A patent/CN102770147A/zh active Pending
- 2010-12-30 US US13/519,829 patent/US20120329993A1/en not_active Abandoned
- 2010-12-30 CN CN2010800648368A patent/CN102770439A/zh active Pending
- 2010-12-30 US US13/519,832 patent/US20130023480A1/en not_active Abandoned
- 2010-12-30 EP EP10841758.5A patent/EP2519117A4/en not_active Withdrawn
- 2010-12-30 CN CN201410168443.1A patent/CN103988973A/zh active Pending
- 2010-12-30 CN CN201080064208XA patent/CN102762584A/zh active Pending
- 2010-12-30 CN CN201080064855.0A patent/CN102781255B/zh not_active Expired - Fee Related
- 2010-12-30 BR BR112012016232A patent/BR112012016232A2/pt not_active IP Right Cessation
- 2010-12-30 CA CA2785599A patent/CA2785599A1/en not_active Abandoned
- 2010-12-30 EP EP10841760.1A patent/EP2785730A1/en not_active Withdrawn
- 2010-12-30 CN CN2010800648423A patent/CN102781459A/zh active Pending
- 2010-12-30 WO PCT/US2010/062556 patent/WO2011082338A1/en not_active Ceased
- 2010-12-30 WO PCT/US2010/062553 patent/WO2011082335A2/en not_active Ceased
- 2010-12-30 US US13/519,842 patent/US20130023649A1/en not_active Abandoned
- 2010-12-30 JP JP2012547316A patent/JP2013516431A/ja active Pending
- 2010-12-30 JP JP2012547309A patent/JP2013516427A/ja active Pending
- 2010-12-30 CA CA2785736A patent/CA2785736A1/en not_active Abandoned
- 2010-12-30 WO PCT/US2010/062591 patent/WO2011082358A1/en not_active Ceased
- 2010-12-30 US US13/519,848 patent/US20120289683A1/en not_active Abandoned
- 2010-12-30 JP JP2012547311A patent/JP2013516429A/ja active Pending
- 2010-12-30 BR BR112012016225A patent/BR112012016225A2/pt active Search and Examination
- 2010-12-30 EP EP10841740.3A patent/EP2519251A4/en not_active Withdrawn
- 2010-12-30 US US13/519,840 patent/US20120302736A1/en not_active Abandoned
- 2010-12-30 WO PCT/US2010/062592 patent/WO2011082359A1/en not_active Ceased
- 2010-12-30 EP EP10841743.7A patent/EP2519535A4/en not_active Withdrawn
- 2010-12-30 WO PCT/US2010/062594 patent/WO2011082360A1/en not_active Ceased
- 2010-12-30 JP JP2012547317A patent/JP2013516432A/ja active Pending
-
2015
- 2015-06-11 JP JP2015118467A patent/JP2015157873A/ja not_active Abandoned
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