JP2013515013A5 - - Google Patents

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Publication number
JP2013515013A5
JP2013515013A5 JP2012545019A JP2012545019A JP2013515013A5 JP 2013515013 A5 JP2013515013 A5 JP 2013515013A5 JP 2012545019 A JP2012545019 A JP 2012545019A JP 2012545019 A JP2012545019 A JP 2012545019A JP 2013515013 A5 JP2013515013 A5 JP 2013515013A5
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JP
Japan
Prior art keywords
antibody
amino acid
acid sequence
antibody fragment
fragment according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2012545019A
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English (en)
Japanese (ja)
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JP2013515013A (ja
JP5992831B2 (ja
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Priority claimed from PCT/AU2010/001741 external-priority patent/WO2011075789A1/en
Publication of JP2013515013A publication Critical patent/JP2013515013A/ja
Publication of JP2013515013A5 publication Critical patent/JP2013515013A5/ja
Application granted granted Critical
Publication of JP5992831B2 publication Critical patent/JP5992831B2/ja
Active legal-status Critical Current
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JP2012545019A 2009-12-24 2010-12-23 非機能性オリゴマーp2x7受容体に対する抗体 Active JP5992831B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2009906286 2009-12-24
AU2009906286A AU2009906286A0 (en) 2009-12-24 Anti P2X7 receptor antibodies and fragments thereof
PCT/AU2010/001741 WO2011075789A1 (en) 2009-12-24 2010-12-23 Antibodies to non-functional oligomeric p2x7 receptors

Publications (3)

Publication Number Publication Date
JP2013515013A JP2013515013A (ja) 2013-05-02
JP2013515013A5 true JP2013515013A5 (https=) 2014-02-13
JP5992831B2 JP5992831B2 (ja) 2016-09-14

Family

ID=44194835

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012545019A Active JP5992831B2 (ja) 2009-12-24 2010-12-23 非機能性オリゴマーp2x7受容体に対する抗体

Country Status (9)

Country Link
US (2) US8835609B2 (https=)
EP (2) EP3321285B1 (https=)
JP (1) JP5992831B2 (https=)
CN (1) CN102762595B (https=)
AU (1) AU2010336032C1 (https=)
BR (1) BR112012015561B1 (https=)
CA (1) CA2784345C (https=)
ES (2) ES2667003T3 (https=)
WO (1) WO2011075789A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1360203B1 (en) 2001-01-17 2008-12-24 Intreat Pty Limited Antibodies to non-functional p 2 x 7 receptor diagnosis and treatment of cancers and other conditions
AU2008299593B2 (en) 2007-09-14 2013-04-18 Biosceptre International Limited Novel P2X7 epitopes
AU2008299594B2 (en) 2007-09-14 2013-10-03 Biosceptre International Limited Purinergic (P2X) receptors in extra-cellular body fluid
BRPI0915367B8 (pt) 2008-07-04 2021-05-25 Biosceptre International Ltd peptídeo anti-p2x7
ES2904911T3 (es) 2009-08-20 2022-04-06 Biosceptre Aust Pty Ltd Anticuerpos anti-receptor P2X7 y fragmentos de los mismos
JP5992831B2 (ja) 2009-12-24 2016-09-14 バイオセプター・(オーストラリア)・ピーティーワイ・リミテッド 非機能性オリゴマーp2x7受容体に対する抗体
CN106310245A (zh) 2010-09-10 2017-01-11 生物权威(澳大利亚)有限责任公司 陪伴动物治疗
US9566318B2 (en) * 2011-07-01 2017-02-14 Biosceptre (Aust) Pty Ltd Combination therapy
US20150239956A1 (en) * 2012-06-27 2015-08-27 Asahi Kasei Medical Co., Ltd. High-affinity antibody and method for manufacturing the same
US20180037650A1 (en) * 2015-04-02 2018-02-08 Biosceptre (Uk) Limited Pain Treatment
EP3347474B1 (en) 2015-09-11 2020-11-04 Biosceptre (UK) Limited Chimeric antigen receptors and uses thereof
CN109862883A (zh) 2016-10-21 2019-06-07 生物权威(英国)有限公司 细胞毒性颗粒
US11629184B2 (en) 2018-02-23 2023-04-18 Remd Biotherapeutics, Inc. Calcitonin gene-related peptide (CGRP) antagonist antibodies
EP3797164A4 (en) 2018-05-21 2022-03-02 Biosceptre (Aust) Pty Ltd CHIMERIC ANTIGEN RECEPTORS WITH MODIFIED LINKER DOMAINS AND THEIR USES
WO2019229296A1 (en) 2018-05-29 2019-12-05 Teknologian Tutkimuskeskus Vtt Oy Anti-thyroid hormone (t4) recombinant antibody or antigen binding fragment
CN110054691B (zh) * 2019-05-09 2021-09-07 潍坊医学院 一种抗人p2rx7单克隆抗体的杂交瘤细胞系
WO2021019222A1 (en) * 2019-07-26 2021-02-04 Biosceptre (Uk) Limited P2x7 receptor targeted therapy
JP2024510739A (ja) * 2021-03-11 2024-03-11 バイオセプター (オースト) プロプライエタリー・リミテッド 新規な細胞治療システム
MX2023015028A (es) * 2021-09-01 2024-02-16 Biosceptre Aust Pty Ltd Nuevos aglutinantes del p2x7 disfuncional.

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IE920765A1 (en) 1991-03-12 1992-09-23 Scripps Research Inst Cell surface receptors homologous to coagulation factors v¹and viii
WO1995033048A2 (en) 1994-05-27 1995-12-07 Glaxo Group Limited P2x receptors (purinoceptor family)
US5981218A (en) 1995-08-09 1999-11-09 Bristol-Myers Squibb Company Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides
JP2001521372A (ja) 1996-04-30 2001-11-06 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ヒトP2x4レセプタースプライス−変異体
US6303338B1 (en) 1996-08-16 2001-10-16 Human Genome Sciences, Inc. Pancreas-derived plasminogen activator inhibitor
US6306393B1 (en) 1997-03-24 2001-10-23 Immunomedics, Inc. Immunotherapy of B-cell malignancies using anti-CD22 antibodies
JP3885177B2 (ja) 1997-03-26 2007-02-21 大塚製薬株式会社 ヒト遺伝子
US6133434A (en) 1997-04-28 2000-10-17 Glaxo Group Limited Purinergic receptor
AU757698C (en) 1998-06-01 2004-04-08 Agensys, Inc. Novel serpentine transmembrane antigens expressed in human cancers and uses thereof
DE19829473C2 (de) 1998-07-01 2000-08-10 Magnus Von Knebel Doeberitz Ch Verfahren zur frühen Diagnose von Carcinomen
EP1157038A4 (en) 1999-02-26 2005-01-19 Smithkline Beecham Corp CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17)
AUPP991199A0 (en) 1999-04-21 1999-05-13 University Of Sydney, The Methods for diagnosing pre-cancerous and cancerous conditions
WO2001030964A2 (en) 1999-10-22 2001-05-03 Lifespan Biosciences, Inc. Anti-cancer nucleic acid and protein targets
AUPR201500A0 (en) 2000-12-11 2001-01-11 Biosceptre Pty Ltd Methods for identifying pre-neoplastic and neoplastic states in mammals
EP1360203B1 (en) 2001-01-17 2008-12-24 Intreat Pty Limited Antibodies to non-functional p 2 x 7 receptor diagnosis and treatment of cancers and other conditions
NZ565994A (en) * 2001-09-03 2010-02-26 Intreat Pty Ltd Antibodies to non-functional P2X7 receptor, diagnosis and treatment of cancers and other conditions
EP1469072B1 (en) 2003-04-17 2007-08-29 Affectis Pharmaceuticals AG Means and methods for diagnosing and treating affective disorders
CA2607541A1 (en) 2005-05-05 2006-12-28 Medicure International Inc. Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphaste and vitamin b6 related compounds
US7767789B2 (en) 2005-06-02 2010-08-03 University Hopitals of Cleveland Truncated proteins as cancer markers
WO2007027957A2 (en) 2005-08-31 2007-03-08 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
JP2010505426A (ja) 2006-10-10 2010-02-25 バイオスセプター インターナショナル リミテッド 非機能性p2x7受容体に対する抗体を産生するハイブリドーマ
WO2008043146A1 (en) * 2006-10-10 2008-04-17 Biosceptre International Limited Antibodies against non functional p2x7 receptor
AU2008299594B2 (en) 2007-09-14 2013-10-03 Biosceptre International Limited Purinergic (P2X) receptors in extra-cellular body fluid
AU2008299593B2 (en) 2007-09-14 2013-04-18 Biosceptre International Limited Novel P2X7 epitopes
BRPI0915367B8 (pt) 2008-07-04 2021-05-25 Biosceptre International Ltd peptídeo anti-p2x7
ES2904911T3 (es) 2009-08-20 2022-04-06 Biosceptre Aust Pty Ltd Anticuerpos anti-receptor P2X7 y fragmentos de los mismos
JP5992831B2 (ja) 2009-12-24 2016-09-14 バイオセプター・(オーストラリア)・ピーティーワイ・リミテッド 非機能性オリゴマーp2x7受容体に対する抗体
WO2011131472A1 (en) 2010-04-22 2011-10-27 Institut Gustave Roussy Compounds and uses thereof to induce an immunogenic cancer cell death in a subject
CN106310245A (zh) 2010-09-10 2017-01-11 生物权威(澳大利亚)有限责任公司 陪伴动物治疗
US9566318B2 (en) 2011-07-01 2017-02-14 Biosceptre (Aust) Pty Ltd Combination therapy

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