JP2013513651A - テオブロミンのうっ血除去剤との組み合わせおよび咳嗽を治療するためのその使用 - Google Patents
テオブロミンのうっ血除去剤との組み合わせおよび咳嗽を治療するためのその使用 Download PDFInfo
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- JP2013513651A JP2013513651A JP2012543902A JP2012543902A JP2013513651A JP 2013513651 A JP2013513651 A JP 2013513651A JP 2012543902 A JP2012543902 A JP 2012543902A JP 2012543902 A JP2012543902 A JP 2012543902A JP 2013513651 A JP2013513651 A JP 2013513651A
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- decongestant
- theobromine
- cough
- pseudoephedrine
- combination
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- 235000019204 saccharin Nutrition 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 229910001467 sodium calcium phosphate Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000008347 soybean phospholipid Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
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- 229940116362 tragacanth Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 210000001186 vagus nerve Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
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- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/GB2010/052085 WO2011073646A1 (en) | 2009-12-14 | 2010-12-14 | Combination of theobromine with a decongestant and its use for the treatment of cough |
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| JP2015189231A Pending JP2016040279A (ja) | 2009-12-14 | 2015-09-28 | テオブロミンのうっ血除去剤との組み合わせおよび咳嗽を治療するためのその使用 |
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| JP2015189231A Pending JP2016040279A (ja) | 2009-12-14 | 2015-09-28 | テオブロミンのうっ血除去剤との組み合わせおよび咳嗽を治療するためのその使用 |
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| JP (2) | JP2013513651A (enExample) |
| CN (2) | CN102740843A (enExample) |
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| IL (1) | IL220383A (enExample) |
| MX (1) | MX343222B (enExample) |
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| ZA (1) | ZA201204293B (enExample) |
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| US10016437B2 (en) | 2009-06-16 | 2018-07-10 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| GB201111485D0 (en) * | 2011-07-05 | 2011-08-17 | Biocopea Ltd | Drug composition and its use in therapy |
| US9308211B2 (en) | 2009-06-16 | 2016-04-12 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| US9314465B2 (en) | 2009-06-16 | 2016-04-19 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| GB0910375D0 (en) | 2009-06-16 | 2009-07-29 | Biocopea Ltd | Drug composition and its use in therapy |
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| CA2170488A1 (en) * | 1993-09-07 | 1995-03-16 | Sekhar Mitra | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
| HUP9700654A2 (hu) | 1997-03-26 | 1999-09-28 | Dezső Korbonits | Teobromin tartalmú köhögéscsillapító készítmények |
| US6417206B1 (en) * | 2001-01-26 | 2002-07-09 | Medpointe Healthcare Inc. | Antitussive/antihist aminic/decongestant compositions |
| JP2002308761A (ja) * | 2001-04-09 | 2002-10-23 | Taisho Pharmaceut Co Ltd | 風邪用咳止め薬 |
| JP2003128549A (ja) * | 2001-08-15 | 2003-05-08 | Rohto Pharmaceut Co Ltd | 粘膜適用組成物 |
| RU2311919C2 (ru) * | 2002-12-30 | 2007-12-10 | Каунсел Оф Сайнтифик Энд Индастриал Рисерч | Разработка противокашлевой и смягчающей горло травяной композиции |
| US20040202677A1 (en) * | 2003-04-10 | 2004-10-14 | Hopkins Kevin J. | Method of enhanced regional body fat reduction |
| US20060153926A1 (en) * | 2005-01-10 | 2006-07-13 | Bascom Charles C | Compositions, products and methods for controlling weight in a mammal |
| US20080003280A1 (en) * | 2006-06-26 | 2008-01-03 | Levine Brian M | Combination cough treatment compounds and method of treating common coughs |
| CN100518775C (zh) * | 2007-03-16 | 2009-07-29 | 邓丽菊 | 一种治疗咳喘的药物组合物及其制剂 |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003321357A (ja) * | 2002-05-02 | 2003-11-11 | Rohto Pharmaceut Co Ltd | 内服用組成物 |
Non-Patent Citations (3)
| Title |
|---|
| JOURNAL OF PHARMACOLOGICAL SCIENCES, vol. Ｖｏｌ．１０２，ｐｐ．１３６−１４２, JPN6014045423, 2006, ISSN: 0002927568 * |
| ＴＨＥ ＦＡＳＥＢ ＪＯＵＲＮＡＬ, vol. doi: 10.1096/fj.04-1990fje, JPN6014045421, 2004, ISSN: 0002927567 * |
| WANGEMANN G.: "CLINICAL EXPERIENCE WITH DYSPNOCEDY AN ANTI-ASTHMA DRUG", ARZTLICHE WOCHENSCHRIFT 1950, vol. V5 N17, JPN5013001469, 1950, pages 272 - 273, ISSN: 0002927566 * |
Also Published As
| Publication number | Publication date |
|---|---|
| SG10201408377QA (en) | 2015-02-27 |
| UA105944C2 (uk) | 2014-07-10 |
| PE20121537A1 (es) | 2012-12-21 |
| IL220383A0 (en) | 2012-08-30 |
| ZA201204293B (en) | 2013-02-27 |
| SG181686A1 (en) | 2012-07-30 |
| ECSP12012132A (es) | 2012-09-28 |
| PH12012501203A1 (en) | 2012-11-05 |
| RU2564904C2 (ru) | 2015-10-10 |
| MX343222B (es) | 2016-10-28 |
| BR112012014161A2 (pt) | 2016-05-17 |
| RU2012129839A (ru) | 2014-01-27 |
| CA2784214C (en) | 2018-01-09 |
| CN102740843A (zh) | 2012-10-17 |
| IL220383A (en) | 2017-01-31 |
| EP2512464A1 (en) | 2012-10-24 |
| AU2010332494B2 (en) | 2015-01-15 |
| WO2011073646A1 (en) | 2011-06-23 |
| MX2012006625A (es) | 2012-10-05 |
| CA2784214A1 (en) | 2011-06-23 |
| CO6541630A2 (es) | 2012-10-16 |
| GB0921805D0 (en) | 2010-01-27 |
| NZ600243A (en) | 2013-07-26 |
| CN105816462A (zh) | 2016-08-03 |
| AU2010332494A1 (en) | 2012-06-14 |
| JP2016040279A (ja) | 2016-03-24 |
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