CN102740843A - 可可碱与解充血剂的组合及其用于治疗咳嗽的用途 - Google Patents

可可碱与解充血剂的组合及其用于治疗咳嗽的用途 Download PDF

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Publication number
CN102740843A
CN102740843A CN2010800570306A CN201080057030A CN102740843A CN 102740843 A CN102740843 A CN 102740843A CN 2010800570306 A CN2010800570306 A CN 2010800570306A CN 201080057030 A CN201080057030 A CN 201080057030A CN 102740843 A CN102740843 A CN 102740843A
Authority
CN
China
Prior art keywords
theobromine
decongestant
cough
pseudoephedrine
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800570306A
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English (en)
Chinese (zh)
Inventor
约翰·布鲁
罗宾·马克·班尼斯特尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reyes Leather Co ltd Ethiopia Lancome
Infirst Healthcare Ltd
Original Assignee
Biocopea Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocopea Ltd filed Critical Biocopea Ltd
Publication of CN102740843A publication Critical patent/CN102740843A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2010800570306A 2009-12-14 2010-12-14 可可碱与解充血剂的组合及其用于治疗咳嗽的用途 Pending CN102740843A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0921805.8 2009-12-14
GBGB0921805.8A GB0921805D0 (en) 2009-12-14 2009-12-14 Drug composition and its use in therapy
PCT/GB2010/052085 WO2011073646A1 (en) 2009-12-14 2010-12-14 Combination of theobromine with a decongestant and its use for the treatment of cough

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201610214436.XA Division CN105816462A (zh) 2009-12-14 2010-12-14 可可碱的药物组合及其在治疗中的用途

Publications (1)

Publication Number Publication Date
CN102740843A true CN102740843A (zh) 2012-10-17

Family

ID=41667045

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2010800570306A Pending CN102740843A (zh) 2009-12-14 2010-12-14 可可碱与解充血剂的组合及其用于治疗咳嗽的用途
CN201610214436.XA Pending CN105816462A (zh) 2009-12-14 2010-12-14 可可碱的药物组合及其在治疗中的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201610214436.XA Pending CN105816462A (zh) 2009-12-14 2010-12-14 可可碱的药物组合及其在治疗中的用途

Country Status (19)

Country Link
EP (1) EP2512464A1 (enExample)
JP (2) JP2013513651A (enExample)
CN (2) CN102740843A (enExample)
AU (1) AU2010332494B2 (enExample)
BR (1) BR112012014161A2 (enExample)
CA (1) CA2784214C (enExample)
CO (1) CO6541630A2 (enExample)
EC (1) ECSP12012132A (enExample)
GB (1) GB0921805D0 (enExample)
IL (1) IL220383A (enExample)
MX (1) MX343222B (enExample)
NZ (1) NZ600243A (enExample)
PE (1) PE20121537A1 (enExample)
PH (1) PH12012501203A1 (enExample)
RU (1) RU2564904C2 (enExample)
SG (2) SG10201408377QA (enExample)
UA (1) UA105944C2 (enExample)
WO (1) WO2011073646A1 (enExample)
ZA (1) ZA201204293B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040202677A1 (en) * 2003-04-10 2004-10-14 Hopkins Kevin J. Method of enhanced regional body fat reduction
CN101024014A (zh) * 2007-03-16 2007-08-29 邓丽菊 一种治疗咳喘的药物组合物及其制剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2170488A1 (en) * 1993-09-07 1995-03-16 Sekhar Mitra Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive
HUP9700654A2 (hu) 1997-03-26 1999-09-28 Dezső Korbonits Teobromin tartalmú köhögéscsillapító készítmények
US6417206B1 (en) * 2001-01-26 2002-07-09 Medpointe Healthcare Inc. Antitussive/antihist aminic/decongestant compositions
JP2002308761A (ja) * 2001-04-09 2002-10-23 Taisho Pharmaceut Co Ltd 風邪用咳止め薬
JP2003128549A (ja) * 2001-08-15 2003-05-08 Rohto Pharmaceut Co Ltd 粘膜適用組成物
JP4377564B2 (ja) * 2002-05-02 2009-12-02 ロート製薬株式会社 内服用組成物
RU2311919C2 (ru) * 2002-12-30 2007-12-10 Каунсел Оф Сайнтифик Энд Индастриал Рисерч Разработка противокашлевой и смягчающей горло травяной композиции
US20060153926A1 (en) * 2005-01-10 2006-07-13 Bascom Charles C Compositions, products and methods for controlling weight in a mammal
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040202677A1 (en) * 2003-04-10 2004-10-14 Hopkins Kevin J. Method of enhanced regional body fat reduction
CN101024014A (zh) * 2007-03-16 2007-08-29 邓丽菊 一种治疗咳喘的药物组合物及其制剂

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MINAMIZAWA K 等: ""Effect of d-Pseudoephedrine on Cough Reflex and Its Mode of Action in Guinea Pigs", 《JOURNAL OF PHARMACOLOGICAL SCIENCES》 *
USMANI OS 等: "Theobromine inhibits sensory nerve activation and cough", 《THE FASEB JOURNAL》 *

Also Published As

Publication number Publication date
SG10201408377QA (en) 2015-02-27
UA105944C2 (uk) 2014-07-10
PE20121537A1 (es) 2012-12-21
IL220383A0 (en) 2012-08-30
ZA201204293B (en) 2013-02-27
SG181686A1 (en) 2012-07-30
ECSP12012132A (es) 2012-09-28
JP2013513651A (ja) 2013-04-22
PH12012501203A1 (en) 2012-11-05
RU2564904C2 (ru) 2015-10-10
MX343222B (es) 2016-10-28
BR112012014161A2 (pt) 2016-05-17
RU2012129839A (ru) 2014-01-27
CA2784214C (en) 2018-01-09
IL220383A (en) 2017-01-31
EP2512464A1 (en) 2012-10-24
AU2010332494B2 (en) 2015-01-15
WO2011073646A1 (en) 2011-06-23
MX2012006625A (es) 2012-10-05
CA2784214A1 (en) 2011-06-23
CO6541630A2 (es) 2012-10-16
GB0921805D0 (en) 2010-01-27
NZ600243A (en) 2013-07-26
CN105816462A (zh) 2016-08-03
AU2010332494A1 (en) 2012-06-14
JP2016040279A (ja) 2016-03-24

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: THE FIRST MEDICAL HEALTH CARE CO., LTD.

Free format text: FORMER OWNER: RUISI PIKOU PIYA CO., LTD.

Effective date: 20141210

Owner name: RUISI PIKOU PIYA CO., LTD.

Free format text: FORMER OWNER: BIOCOPEA LTD.

Effective date: 20141210

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20141210

Address after: London, England

Applicant after: InFirst Healthcare Ltd.

Address before: Dublin, Ireland

Applicant before: Reyes Leather Co.,Ltd. Ethiopia Lancome

Effective date of registration: 20141210

Address after: Dublin, Ireland

Applicant after: Reyes Leather Co.,Ltd. Ethiopia Lancome

Address before: London, England

Applicant before: BIOCOPEA Ltd.

RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20121017