|
JP2884452B2
(ja)
|
1991-10-09 |
1999-04-19 |
清水建設株式会社 |
セグメントを利用した立坑構築工法
|
|
LT1993360T
(lt)
|
2005-12-28 |
2017-06-12 |
Vertex Pharmaceuticals Incorporated |
N-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksochinolin-3-karboksamido kieta forma
|
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
|
AU2009204483B2
(en)
|
2008-01-04 |
2014-03-13 |
Intellikine, Llc |
Certain chemical entities, compositions and methods
|
|
EP2334315B1
(en)
|
2008-09-03 |
2023-01-18 |
NoNO Inc. |
Agents and methods for treatment of pain
|
|
AU2010327936B2
(en)
*
|
2009-12-11 |
2015-08-20 |
Nono Inc. |
Agents and methods for treating ischemic and other diseases
|
|
JP5951600B2
(ja)
|
2010-05-21 |
2016-07-13 |
インフィニティー ファーマシューティカルズ, インコーポレイテッド |
キナーゼ調節のための、化合物、組成物および方法
|
|
AU2011202542A1
(en)
*
|
2010-07-14 |
2012-02-02 |
Indian Institute Of Science |
Benzothiophene carboxamide compounds, composition and applications thereof
|
|
EP3056486B1
(en)
|
2010-07-16 |
2018-07-11 |
AbbVie Ireland Unlimited Company |
Process for preparing intermediates for antiviral compounds
|
|
EP3461556A1
(en)
|
2010-07-16 |
2019-04-03 |
AbbVie Ireland Unlimited Company |
Phosphine ligands for catalytic reactions
|
|
US9255074B2
(en)
|
2010-07-16 |
2016-02-09 |
Abbvie Inc. |
Process for preparing antiviral compounds
|
|
US8975443B2
(en)
|
2010-07-16 |
2015-03-10 |
Abbvie Inc. |
Phosphine ligands for catalytic reactions
|
|
CA2816983A1
(en)
|
2010-11-05 |
2012-05-10 |
Senomyx, Inc. |
Compounds useful as modulators of trpm8
|
|
WO2012071369A2
(en)
|
2010-11-24 |
2012-05-31 |
The Trustees Of Columbia University In The City Of New York |
A non-retinoid rbp4 antagonist for treatment of age-related macular degeneration and stargardt disease
|
|
KR20180080358A
(ko)
|
2011-01-10 |
2018-07-11 |
인피니티 파마슈티칼스, 인코포레이티드 |
이소퀴놀린온 및 이의 고체 형태의 제조 방법
|
|
EP2720695A4
(en)
*
|
2011-06-15 |
2014-11-12 |
Nono Inc |
ACTIVE AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES
|
|
EP2734530A1
(en)
|
2011-07-19 |
2014-05-28 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
KR20130016041A
(ko)
*
|
2011-08-04 |
2013-02-14 |
재단법인 의약바이오컨버젼스연구단 |
신규한 아닐린 유도체 및 이의 용도
|
|
CN103998442B
(zh)
|
2011-08-29 |
2016-09-14 |
无限药品股份有限公司 |
杂环化合物及其用途
|
|
WO2013119931A1
(en)
*
|
2012-02-10 |
2013-08-15 |
The Board Of Regents Of The University Of Texas System |
Modulators of exchange proteins directly activated by camp (epacs)
|
|
US9051299B2
(en)
|
2012-03-29 |
2015-06-09 |
Merck Sharp & Dohme Corp. |
Imidazolyl methyl piperidine T-type calcium channel antagonists
|
|
WO2013166037A1
(en)
|
2012-05-01 |
2013-11-07 |
The Trustees Of Columbia University In The City Of New York |
Non-retinoid antagonists for treatment of eye disorders
|
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
|
CN103570705B
(zh)
*
|
2012-07-18 |
2017-01-25 |
中国医学科学院医药生物技术研究所 |
取代的n‑((1',3'‑杂唑‑4'‑基)‑甲基)‑4‑苯甲酰基六氢吡啶类化合物及其用途
|
|
JP6223452B2
(ja)
|
2012-09-07 |
2017-11-01 |
ノバルティス アーゲー |
インドールカルボキサミド誘導体およびその使用
|
|
BR102012024778A2
(pt)
*
|
2012-09-28 |
2014-08-19 |
Cristalia Prod Quimicos Farm |
Compostos heteroaromáticos; processo para preparar os compostos, composições farmacêuticas, usos e método de tratamento para as dores aguda e crônica
|
|
IL291945B2
(en)
|
2012-11-01 |
2025-11-01 |
Infinity Pharmaceuticals Inc |
Treatment of cancers using pi3 kinase isoform modulators
|
|
WO2014079545A1
(en)
*
|
2012-11-20 |
2014-05-30 |
Ktb Tumorforschungsgesellschaft Mbh |
Thioether derivatives as protein kinase inhibitors
|
|
EP2733146A1
(en)
*
|
2012-11-20 |
2014-05-21 |
KTB Tumorforschungsgesellschaft mbH |
Thioether derivatives as protein kinase inhibitors
|
|
KR20150111356A
(ko)
|
2013-01-25 |
2015-10-05 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
화합물
|
|
TWI644899B
(zh)
|
2013-02-04 |
2018-12-21 |
健生藥品公司 |
Flap調節劑
|
|
US9079866B2
(en)
|
2013-02-04 |
2015-07-14 |
Janssen Pharmaceutica Nv |
Flap modulators
|
|
WO2014151959A1
(en)
*
|
2013-03-14 |
2014-09-25 |
The Trustees Of Columbia University In The City Of New York |
N-alkyl-2-phenoxyethanamines, their preparation and use
|
|
EP3495357B1
(en)
|
2013-03-14 |
2021-05-05 |
The Trustees of Columbia University in the City of New York |
4-phenylpiperidines, their preparation and use
|
|
US9944644B2
(en)
|
2013-03-14 |
2018-04-17 |
The Trustees Of Columbia University In The City Of New York |
Octahydropyrrolopyrroles their preparation and use
|
|
US9637450B2
(en)
|
2013-03-14 |
2017-05-02 |
The Trustees Of Columbia University In The City Of New York |
Octahydrocyclopentapyrroles, their preparation and use
|
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
|
WO2015039333A1
(en)
*
|
2013-09-22 |
2015-03-26 |
Merck Sharp & Dohme Corp. |
TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF
|
|
CA2931219A1
(en)
*
|
2013-12-20 |
2015-06-25 |
Laboratorios Del Dr. Esteve, S.A. |
Piperidine compounds having multimodal activity against pain
|
|
ES2796090T3
(es)
|
2014-02-10 |
2020-11-25 |
Inst Curie |
Uso de moduladores MCOLN-1 para regular la migración celular
|
|
US20150320755A1
(en)
|
2014-04-16 |
2015-11-12 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
BR112016025356B1
(pt)
|
2014-04-30 |
2023-04-18 |
The Trustees Of Columbia University In The City Of New York |
Compostos de 4-fenilpiperidinas substituídas, composições e seus usos
|
|
US20170273922A1
(en)
*
|
2014-10-03 |
2017-09-28 |
The Royal Institution For The Advacement Of Learning/Mcgill University |
Urea and bis-urea based compounds and analogues thereof useful in the treatment of androgen receptor mediated diseases or disorders
|
|
EP3204358B1
(en)
|
2014-10-07 |
2018-09-19 |
Vertex Pharmaceuticals Incorporated |
Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
|
|
RS61504B1
(sr)
|
2014-10-24 |
2021-03-31 |
Takeda Pharmaceuticals Co |
Jedinjenja heteroarila za lečenje oftalmičkih bolesti
|
|
WO2016077793A1
(en)
*
|
2014-11-14 |
2016-05-19 |
Children's Hospital Medical Center |
Sos1 inhibitors for cancer treatment
|
|
PL3097102T3
(pl)
|
2015-03-04 |
2018-04-30 |
Gilead Sciences Inc |
Związki 4,6-diamino-pirydo[3,2-d]pirymidyny modulujące działanie receptora toll-podobnego
|
|
US9737512B2
(en)
|
2015-03-11 |
2017-08-22 |
The Board Of Regents Of The University Of Texas System |
Methods and compositions for treating chronic pain
|
|
WO2017007755A1
(en)
|
2015-07-06 |
2017-01-12 |
Rodin Therapeutics, Inc. |
Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
|
|
LT3319959T
(lt)
|
2015-07-06 |
2021-12-27 |
Alkermes, Inc. |
Histono deacetilazės hetero-halogeno inhibitoriai
|
|
US10392371B2
(en)
|
2015-10-01 |
2019-08-27 |
Senomyx, Inc. |
Compounds useful as modulators of TRPM8
|
|
US10450274B2
(en)
*
|
2015-12-07 |
2019-10-22 |
Hinova Pharmaceuticals Inc. |
Quinoline compounds, preparation methods thereof, and uses thereof as urate transporter inhibitor drug
|
|
CA3028718A1
(en)
|
2016-06-24 |
2017-12-28 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
ES2826748T3
(es)
|
2016-09-02 |
2021-05-19 |
Gilead Sciences Inc |
Derivados de 4,6-diamino-pirido[3,2-d]pirimidina como moduladores de receptores de tipo Toll
|
|
KR102268448B1
(ko)
|
2016-09-02 |
2021-06-22 |
길리애드 사이언시즈, 인코포레이티드 |
톨 유사 수용체 조정제 화합물
|
|
CN106565643A
(zh)
*
|
2016-10-31 |
2017-04-19 |
北京大学 |
D‑3‑磷酸甘油酸脱氢酶别构抑制剂及其应用
|
|
US10722489B2
(en)
*
|
2016-10-31 |
2020-07-28 |
Peking University |
D-3-phosphoglycerate dehydrogenase allosteric inhibitor and use thereof
|
|
US10793567B2
(en)
|
2017-01-11 |
2020-10-06 |
Rodin Therapeutics, Inc. |
Bicyclic inhibitors of histone deacetylase
|
|
CN106822897B
(zh)
*
|
2017-02-17 |
2018-10-19 |
河北盛华尔生物医疗科技有限公司 |
靶向下调trpm7基因表达在提高肺鳞癌化疗敏感性方面的应用
|
|
CN110709394B
(zh)
*
|
2017-03-31 |
2025-02-21 |
中美博瑞纳制药有限公司 |
可用作alcat1抑制剂的化合物
|
|
WO2018232160A1
(en)
*
|
2017-06-15 |
2018-12-20 |
Belite Bio, Inc |
Methods of treating metabolic diseases with phenoxyethylamides
|
|
EP3638239A4
(en)
|
2017-06-15 |
2021-03-10 |
Belite Bio, Inc |
METHOD OF TREATMENT OF RBP4-RELATED DISEASES WITH TRIAZOLOPYRIDINES
|
|
US11389444B2
(en)
|
2017-06-15 |
2022-07-19 |
Belite Bio, Inc |
Methods of treating metabolic diseases with fused bicyclic pyrazoles
|
|
EA039417B1
(ru)
|
2017-08-07 |
2022-01-25 |
Родин Терапеутикс, Инк. |
Бициклические ингибиторы гистондеацетилазы
|
|
PY19106549A
(es)
*
|
2018-12-21 |
2021-07-13 |
Bayer Ag |
1,3,4-oxadiazoles y derivados de éstos como nuevos agentes fungicidas
|
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI879779B
(zh)
|
2019-06-28 |
2025-04-11 |
美商基利科學股份有限公司 |
類鐸受體調節劑化合物的製備方法
|
|
KR20220061093A
(ko)
|
2019-07-08 |
2022-05-12 |
벨라이트 바이오 엘엘씨 |
Rbp4 억제제의 제제 및 사용 방법
|
|
US11091447B2
(en)
|
2020-01-03 |
2021-08-17 |
Berg Llc |
UBE2K modulators and methods for their use
|
|
WO2021257857A1
(en)
|
2020-06-19 |
2021-12-23 |
Incyte Corporation |
Naphthyridinone compounds as jak2 v617f inhibitors
|
|
US11753413B2
(en)
|
2020-06-19 |
2023-09-12 |
Incyte Corporation |
Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors
|
|
US11767323B2
(en)
|
2020-07-02 |
2023-09-26 |
Incyte Corporation |
Tricyclic pyridone compounds as JAK2 V617F inhibitors
|
|
KR20230057341A
(ko)
|
2020-07-02 |
2023-04-28 |
인사이트 코포레이션 |
Jak2 v617f 억제제로서 삼환계 우레아 화합물
|
|
WO2022046989A1
(en)
|
2020-08-27 |
2022-03-03 |
Incyte Corporation |
Tricyclic urea compounds as jak2 v617f inhibitors
|
|
WO2022119823A1
(en)
*
|
2020-12-04 |
2022-06-09 |
The Johns Hopkins University |
Compounds and their use for treating neuropathic pain
|
|
WO2022140231A1
(en)
|
2020-12-21 |
2022-06-30 |
Incyte Corporation |
Deazaguaine compounds as jak2 v617f inhibitors
|
|
WO2022148781A1
(en)
|
2021-01-05 |
2022-07-14 |
Institut Curie |
Combination of mcoln activators and immune checkpoint inhibitors
|
|
AR125273A1
(es)
|
2021-02-25 |
2023-07-05 |
Incyte Corp |
Lactamas espirocíclicas como inhibidores de jak2 v617f
|
|
KR102905373B1
(ko)
*
|
2021-04-08 |
2025-12-29 |
주식회사 종근당 |
히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 싸이오카보닐 화합물 및 이를 포함하는 약제학적 조성물
|
|
CN114685371A
(zh)
*
|
2022-03-08 |
2022-07-01 |
四川大学 |
吡唑甲酰胺衍生物及其制备方法和用途
|
|
PE20251706A1
(es)
|
2022-03-17 |
2025-07-02 |
Incyte Corp |
Compuestos de urea triciclica como inhibidores de v617f de jak2
|
|
WO2024059524A1
(en)
*
|
2022-09-12 |
2024-03-21 |
Hotspot Therapeutics, Inc. |
Pyrazolylcarboxamide compounds and their use in therapy
|