JP2013511530A5 - - Google Patents
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- JP2013511530A5 JP2013511530A5 JP2012540005A JP2012540005A JP2013511530A5 JP 2013511530 A5 JP2013511530 A5 JP 2013511530A5 JP 2012540005 A JP2012540005 A JP 2012540005A JP 2012540005 A JP2012540005 A JP 2012540005A JP 2013511530 A5 JP2013511530 A5 JP 2013511530A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- amino acid
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- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001413 amino acids Chemical class 0.000 claims description 74
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 66
- 239000000203 mixture Substances 0.000 claims description 26
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 21
- 208000016604 Lyme disease Diseases 0.000 claims description 18
- 241000589968 Borrelia Species 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 14
- 239000000427 antigen Substances 0.000 claims description 10
- 102000036639 antigens Human genes 0.000 claims description 10
- 108091007433 antigens Proteins 0.000 claims description 10
- 101800001415 Bri23 peptide Proteins 0.000 claims description 8
- 102400000107 C-terminal peptide Human genes 0.000 claims description 8
- 101800000655 C-terminal peptide Proteins 0.000 claims description 8
- 230000015572 biosynthetic process Effects 0.000 claims description 8
- 239000007787 solid Substances 0.000 claims description 7
- 239000012634 fragment Substances 0.000 claims description 6
- 108010090804 Streptavidin Proteins 0.000 claims description 5
- 238000003556 assay Methods 0.000 claims description 4
- 239000011324 bead Substances 0.000 claims description 4
- 239000003153 chemical reaction reagent Substances 0.000 claims description 4
- 238000002372 labelling Methods 0.000 claims description 4
- 101800001693 R-peptide Proteins 0.000 claims description 3
- 238000004458 analytical method Methods 0.000 claims description 3
- 239000003446 ligand Substances 0.000 claims description 3
- 241000589969 Borreliella burgdorferi Species 0.000 claims description 2
- 238000012286 ELISA Assay Methods 0.000 claims description 2
- 238000007818 agglutination assay Methods 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 2
- 238000003018 immunoassay Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 210000003296 saliva Anatomy 0.000 claims description 2
- 210000002966 serum Anatomy 0.000 claims description 2
- 241000894007 species Species 0.000 claims description 2
- 210000002700 urine Anatomy 0.000 claims description 2
- 235000001014 amino acid Nutrition 0.000 claims 16
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
- 108090001008 Avidin Proteins 0.000 claims 3
- 102000007562 Serum Albumin Human genes 0.000 claims 2
- 108010071390 Serum Albumin Proteins 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 241000282465 Canis Species 0.000 claims 1
- 101710120037 Toxin CcdB Proteins 0.000 claims 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- -1 Q and E Chemical class 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26209909P | 2009-11-17 | 2009-11-17 | |
| US61/262,099 | 2009-11-17 | ||
| PCT/US2010/057053 WO2011063003A2 (en) | 2009-11-17 | 2010-11-17 | Peptides and methods for the detection of lyme disease antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013511530A JP2013511530A (ja) | 2013-04-04 |
| JP2013511530A5 true JP2013511530A5 (enExample) | 2013-12-26 |
Family
ID=44060312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540005A Pending JP2013511530A (ja) | 2009-11-17 | 2010-11-17 | ライム病抗体の検出のためのペプチドおよび方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8568989B2 (enExample) |
| EP (1) | EP2501719B1 (enExample) |
| JP (1) | JP2013511530A (enExample) |
| KR (1) | KR20120096932A (enExample) |
| CN (1) | CN102791727A (enExample) |
| AU (1) | AU2010322085B2 (enExample) |
| CA (1) | CA2781110C (enExample) |
| WO (1) | WO2011063003A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8758772B2 (en) | 2011-11-04 | 2014-06-24 | Abaxis, Inc. | Peptides and methods for the detection of lyme disease antibodies |
| DK3489685T3 (da) | 2011-11-21 | 2023-12-04 | Zoetis Services Llc | Signalforstærkning i sidestrømning og tilsvarende immunoassays |
| JP2013164414A (ja) * | 2012-01-13 | 2013-08-22 | Nippon Meat Packers Inc | 抗菌ペプチドを用いた微生物の検出方法及び検出用キット |
| US9194870B2 (en) | 2014-01-21 | 2015-11-24 | Abaxis, Inc. | Peptides, devices, and methods for the detection of Anaplasma antibodies |
| US20150293086A1 (en) * | 2014-04-14 | 2015-10-15 | Abreos Biosciences, Inc. | Lateral flow immunoassay |
| TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
| US11061028B2 (en) * | 2014-09-24 | 2021-07-13 | Defined Diagnostics, Llc | Compositions and methods for the diagnosis of lyme disease |
| CN104330555B (zh) * | 2014-10-22 | 2016-05-11 | 中国检验检疫科学研究院 | 检测伯氏疏螺旋体抗体的试纸、试纸制备方法及试剂盒 |
| EP4465021A3 (en) | 2015-08-04 | 2025-02-26 | Zoetis Services LLC | Signal amplification in solution-based plasmonic specific-binding partner assays |
| WO2017035389A1 (en) * | 2015-08-27 | 2017-03-02 | Quidel Corporation | Immunoassay test device with two fluid flow paths for detection and differentiation of two or more analytes |
| CN105548577B (zh) * | 2016-02-04 | 2017-09-19 | 安徽医科大学 | 一种琥珀酰‑β‑环糊精修饰的莱姆病检测用蛋白质芯片及其制备与应用 |
| EP3252470B1 (en) * | 2016-06-03 | 2020-07-29 | Te?ted Oy | A method and a solid support for detecting tick-borne microbes in a biological sample |
| USD800912S1 (en) | 2016-06-17 | 2017-10-24 | Abreos Biosciences, Inc. | Point-of-care diagnostic device |
| WO2018031887A1 (en) | 2016-08-12 | 2018-02-15 | Abreos Biosciences, Inc. | Detection and quantification of natalizumab |
| CN106432487A (zh) * | 2016-10-31 | 2017-02-22 | 杭州贝英福生物科技有限公司 | 一种伽氏疏螺旋体多克隆抗体及应用 |
| CN106397589A (zh) * | 2016-10-31 | 2017-02-15 | 杭州贝英福生物科技有限公司 | 一种狭义伯氏疏螺旋体多克隆抗体及应用 |
| KR102486615B1 (ko) | 2017-01-30 | 2023-01-11 | 조에티스 서비시즈 엘엘씨 | 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체 |
| JP7062803B1 (ja) * | 2021-03-31 | 2022-05-06 | 積水メディカル株式会社 | 抗薬物抗体測定方法 |
| EP4220166A1 (en) | 2022-02-01 | 2023-08-02 | Universitat Rovira I Virgili (URV) | In vitro method for detecting antibodies in a sample |
| EP4511656A1 (en) * | 2022-04-04 | 2025-02-26 | Antigen Discovery Inc. | Antigens for detection of early lyme disease |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4366246A (en) | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
| US4888276A (en) | 1986-06-26 | 1989-12-19 | Minnesota Mining And Manufacturing Company | Method and composition for the diagnosis of Lyme disease |
| US4721617A (en) | 1986-08-14 | 1988-01-26 | Regents Of The University Of Minnesota | Vaccine against lyme disease |
| US5385826A (en) | 1989-04-21 | 1995-01-31 | Gundersen Medical Foundation, Ltd. | Diagnostic assay for lyme disease |
| DE4015911A1 (de) | 1989-09-19 | 1991-03-28 | Max Planck Gesellschaft | Impfstoff gegen die lyme-krankheit |
| US5187065A (en) | 1989-12-22 | 1993-02-16 | Schutzer Steven E | Method and materials for detecting lyme disease |
| SG122738A1 (en) | 1990-06-15 | 2006-06-29 | Univ Yale | Compositions and methods for the prevention and diagnosis of lyme disease |
| US5155022A (en) | 1991-02-08 | 1992-10-13 | Becton, Dickinson And Company | Assay for lyme disease |
| US5324630A (en) | 1991-06-28 | 1994-06-28 | The Regents Of The University Of California | Methods and compositions for diagnosing lyme disease |
| US6221363B1 (en) | 1991-07-11 | 2001-04-24 | Baxter Aktiengesellschaft | Vaccine for the prevention of lyme disease |
| WO1993003184A1 (en) | 1991-08-09 | 1993-02-18 | Mccann Associates, Inc. | Method for detecting lyme disease and composition |
| US5965702A (en) | 1991-10-21 | 1999-10-12 | Abbott Laboratories | Borrelia burgdorferi antigens and uses thereof |
| US5618533A (en) | 1992-02-11 | 1997-04-08 | Yale University | Flagellin-based polypeptides for the diagnosis of lyme disease |
| US5308753A (en) | 1992-02-20 | 1994-05-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods for purifying and detecting IGM antibodies |
| US5620862A (en) | 1993-11-24 | 1997-04-15 | University Of Connecticut | Methods for diagnosing early Lyme disease |
| US5932220A (en) | 1995-05-08 | 1999-08-03 | Board Of Regents University Of Texas System | Diagnostic tests for a new spirochete, Borrelia lonestari sp. nov. |
| EP0894143B2 (en) | 1996-02-21 | 2012-04-18 | Board Of Regents, The University Of Texas System | Vmp-like sequences of pathogenic borrelia |
| US6716574B2 (en) | 1996-05-02 | 2004-04-06 | Dako A/S | Osp-C derived peptide fragments |
| US6902893B1 (en) | 1997-06-20 | 2005-06-07 | Gil H. Choi | Lyme disease vaccines |
| ES2270523T3 (es) | 1997-06-30 | 2007-04-01 | The Administrators Of The Tulane Educational Fund | Antigenos de superficie y proteinas utiles en composiciones para la diagnosis y prevencion de la enfermedad de lyme. |
| US6667038B1 (en) | 1999-04-21 | 2003-12-23 | Boston Medical Center Corp. | Prevention, diagnosis and treatment of lyme disease |
| US6475492B1 (en) | 1999-04-28 | 2002-11-05 | The Administrators Of The Tulane Educational Fund | Peptides and assays for the diagnosis of lyme disease |
| US6665652B1 (en) | 1999-07-28 | 2003-12-16 | Richard B. Porwancher | Method of diagnosis of lyme disease |
| CA2446246A1 (en) * | 2001-05-03 | 2002-11-14 | Immunetics, Inc. | Systems and methods for detection of analytes in biological fluids |
| US6838247B2 (en) | 2002-06-19 | 2005-01-04 | Bowen Research And Training | Test for lyme disease |
| EP2292762A3 (en) | 2002-12-20 | 2012-12-12 | Board of Regents, The University of Texas System | VMP-like sequences of pathogenic Borrelia species and strains |
| US20060046310A1 (en) | 2004-08-25 | 2006-03-02 | Zong-Li Xia | Amplification method for solid phase immunoassays |
| US7390626B2 (en) * | 2005-02-25 | 2008-06-24 | Immunosciences Lab., Inc. | Methods and kit for diagnosing tick borne illnesses |
| US8232045B2 (en) | 2005-03-29 | 2012-07-31 | Inverness Medical Switzerland Gmbh | Colloidal metal conjugates |
| WO2007133623A2 (en) * | 2006-05-10 | 2007-11-22 | Biopeptides Corporation | Peptide diagnostic agent for lyme disease |
| US7776618B2 (en) | 2007-03-01 | 2010-08-17 | Church & Dwight Co., Inc. | Diagnostic detection device |
| US8399261B2 (en) | 2007-06-27 | 2013-03-19 | Inbios International, Inc. | Lateral flow assay system and methods for its use |
| EP2058663A1 (en) | 2007-11-12 | 2009-05-13 | Euro-Diagnostica B.V. | Method for the immobilization of an analyte on a solid support |
| JP2009236685A (ja) | 2008-03-27 | 2009-10-15 | Sysmex Corp | クロマトグラフィー用試験具 |
-
2010
- 2010-11-17 WO PCT/US2010/057053 patent/WO2011063003A2/en not_active Ceased
- 2010-11-17 EP EP10832113.4A patent/EP2501719B1/en active Active
- 2010-11-17 JP JP2012540005A patent/JP2013511530A/ja active Pending
- 2010-11-17 US US12/948,209 patent/US8568989B2/en active Active
- 2010-11-17 KR KR1020127015460A patent/KR20120096932A/ko not_active Ceased
- 2010-11-17 CN CN2010800616653A patent/CN102791727A/zh active Pending
- 2010-11-17 CA CA2781110A patent/CA2781110C/en active Active
- 2010-11-17 AU AU2010322085A patent/AU2010322085B2/en active Active
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| Class et al. | Patent application title: Diagnostic, prognostic, therapeutic and screening protocols Inventors: David Andrew Anderson (Melbourne, AU) Mary Louise Garcia (Melbourne, AU) Nadine Carmel Barnes (Melbourne, AU) Khayriyyah Mohd Hanafiah (Melbourne, AU) Alan Lee Landay (Melbourne, AU) |