JP2015504420A5 - - Google Patents
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- JP2015504420A5 JP2015504420A5 JP2014540187A JP2014540187A JP2015504420A5 JP 2015504420 A5 JP2015504420 A5 JP 2015504420A5 JP 2014540187 A JP2014540187 A JP 2014540187A JP 2014540187 A JP2014540187 A JP 2014540187A JP 2015504420 A5 JP2015504420 A5 JP 2015504420A5
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- Prior art keywords
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- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims description 63
- 150000001413 amino acids Chemical class 0.000 claims description 50
- 239000000203 mixture Substances 0.000 claims description 24
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 22
- 208000016604 Lyme disease Diseases 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 13
- 241000589968 Borrelia Species 0.000 claims description 12
- 239000000427 antigen Substances 0.000 claims description 10
- 102000036639 antigens Human genes 0.000 claims description 10
- 108091007433 antigens Proteins 0.000 claims description 10
- 230000015572 biosynthetic process Effects 0.000 claims description 8
- 239000007787 solid Substances 0.000 claims description 7
- 101800001415 Bri23 peptide Proteins 0.000 claims description 6
- 102400000107 C-terminal peptide Human genes 0.000 claims description 6
- 101800000655 C-terminal peptide Proteins 0.000 claims description 6
- 239000012634 fragment Substances 0.000 claims description 5
- 108010090804 Streptavidin Proteins 0.000 claims description 4
- 238000003556 assay Methods 0.000 claims description 4
- 239000011324 bead Substances 0.000 claims description 4
- 239000003153 chemical reaction reagent Substances 0.000 claims description 4
- 238000002372 labelling Methods 0.000 claims description 4
- 239000002245 particle Substances 0.000 claims description 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 3
- 239000003446 ligand Substances 0.000 claims description 3
- 241000589969 Borreliella burgdorferi Species 0.000 claims description 2
- 241001148605 Borreliella garinii Species 0.000 claims description 2
- 238000012286 ELISA Assay Methods 0.000 claims description 2
- 241000283073 Equus caballus Species 0.000 claims description 2
- 238000007818 agglutination assay Methods 0.000 claims description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 2
- 238000003018 immunoassay Methods 0.000 claims description 2
- 241000894007 species Species 0.000 claims description 2
- 238000001262 western blot Methods 0.000 claims description 2
- 108010045069 keyhole-limpet hemocyanin Proteins 0.000 claims 2
- 108090001008 Avidin Proteins 0.000 claims 1
- 108010078791 Carrier Proteins Proteins 0.000 claims 1
- 102000014914 Carrier Proteins Human genes 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 102000007562 Serum Albumin Human genes 0.000 claims 1
- 108010071390 Serum Albumin Proteins 0.000 claims 1
- 101710120037 Toxin CcdB Proteins 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 239000010415 colloidal nanoparticle Substances 0.000 claims 1
- 239000011258 core-shell material Substances 0.000 claims 1
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 239000002077 nanosphere Substances 0.000 claims 1
- 108010087904 neutravidin Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161556061P | 2011-11-04 | 2011-11-04 | |
| US61/556,061 | 2011-11-04 | ||
| PCT/US2012/063594 WO2013067524A1 (en) | 2011-11-04 | 2012-11-05 | Peptides and methods for the detection of lyme disease antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018190592A Division JP2019048811A (ja) | 2011-11-04 | 2018-10-09 | ライム病抗体の検出のためのペプチドおよび方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015504420A JP2015504420A (ja) | 2015-02-12 |
| JP2015504420A5 true JP2015504420A5 (enExample) | 2015-12-24 |
| JP6839485B2 JP6839485B2 (ja) | 2021-03-10 |
Family
ID=48192911
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014540187A Active JP6839485B2 (ja) | 2011-11-04 | 2012-11-05 | ライム病抗体の検出のためのペプチドおよび方法 |
| JP2018190592A Pending JP2019048811A (ja) | 2011-11-04 | 2018-10-09 | ライム病抗体の検出のためのペプチドおよび方法 |
| JP2020160834A Withdrawn JP2021004251A (ja) | 2011-11-04 | 2020-09-25 | ライム病抗体の検出のためのペプチドおよび方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018190592A Pending JP2019048811A (ja) | 2011-11-04 | 2018-10-09 | ライム病抗体の検出のためのペプチドおよび方法 |
| JP2020160834A Withdrawn JP2021004251A (ja) | 2011-11-04 | 2020-09-25 | ライム病抗体の検出のためのペプチドおよび方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US8758772B2 (enExample) |
| EP (3) | EP3502125B1 (enExample) |
| JP (3) | JP6839485B2 (enExample) |
| KR (3) | KR102503883B1 (enExample) |
| CN (1) | CN103998459A (enExample) |
| CA (1) | CA2851540C (enExample) |
| DK (1) | DK3502125T5 (enExample) |
| ES (1) | ES2967710T3 (enExample) |
| FI (1) | FI3502125T3 (enExample) |
| PL (1) | PL3502125T3 (enExample) |
| WO (1) | WO2013067524A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140186861A1 (en) * | 2011-07-11 | 2014-07-03 | Uvic Industry Partnerships Inc. | Soluble treponema pallidum protein tp0453, tp0453-tp0326 fusion protein, and use in syphilis diagnosis |
| US8758772B2 (en) | 2011-11-04 | 2014-06-24 | Abaxis, Inc. | Peptides and methods for the detection of lyme disease antibodies |
| DK3489685T3 (da) | 2011-11-21 | 2023-12-04 | Zoetis Services Llc | Signalforstærkning i sidestrømning og tilsvarende immunoassays |
| US10294531B2 (en) | 2013-10-07 | 2019-05-21 | University Of Central Florida Research Foundation, Inc. | Method, kits and materials for detection of Lyme disease Borrelia sp. infection |
| US9194870B2 (en) | 2014-01-21 | 2015-11-24 | Abaxis, Inc. | Peptides, devices, and methods for the detection of Anaplasma antibodies |
| WO2015148609A2 (en) * | 2014-03-26 | 2015-10-01 | Li-Cor, Inc. | Immunoassays using colloidal crystals |
| US10274491B2 (en) | 2014-07-07 | 2019-04-30 | Veramarx, Inc. | Biomarker signatures for lyme disease and methods of use thereof |
| TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
| US11061028B2 (en) | 2014-09-24 | 2021-07-13 | Defined Diagnostics, Llc | Compositions and methods for the diagnosis of lyme disease |
| EP4465021A3 (en) | 2015-08-04 | 2025-02-26 | Zoetis Services LLC | Signal amplification in solution-based plasmonic specific-binding partner assays |
| WO2017035389A1 (en) * | 2015-08-27 | 2017-03-02 | Quidel Corporation | Immunoassay test device with two fluid flow paths for detection and differentiation of two or more analytes |
| LT3353551T (lt) | 2015-09-25 | 2023-02-10 | Qiagen Sciences, Llc | Kompozicijos ir būdai, skirti laimo ligos diagnozavimui ir laimo ligą sukeliančių spirochetų eliminacijos po gydymo nuspėjimui |
| EP3359558B1 (en) | 2015-10-06 | 2023-12-13 | Bio-Rad Laboratories, Inc. | Borrelia immunoassays and materials therefor |
| EP3400441A4 (en) | 2016-01-06 | 2019-12-25 | Veramarx, Inc. | SIGNATURES OF BIOMARKERS FOR THE DIFFERENTIATION OF LYME DISEASE AND METHODS OF USE THEREOF |
| EP3252470B1 (en) * | 2016-06-03 | 2020-07-29 | Te?ted Oy | A method and a solid support for detecting tick-borne microbes in a biological sample |
| US20170370925A1 (en) * | 2016-06-27 | 2017-12-28 | Tgr Biosciences Pty Ltd. | Lateral Flow Analyte Detection |
| CN106397589A (zh) * | 2016-10-31 | 2017-02-15 | 杭州贝英福生物科技有限公司 | 一种狭义伯氏疏螺旋体多克隆抗体及应用 |
| CN106432487A (zh) * | 2016-10-31 | 2017-02-22 | 杭州贝英福生物科技有限公司 | 一种伽氏疏螺旋体多克隆抗体及应用 |
| KR102486615B1 (ko) | 2017-01-30 | 2023-01-11 | 조에티스 서비시즈 엘엘씨 | 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체 |
| CN106932567B (zh) * | 2017-02-27 | 2018-10-30 | 天津市泌尿外科研究所 | 一种重组蛋白a介导的免疫靶向纳米金的制备方法 |
| US11331019B2 (en) | 2017-08-07 | 2022-05-17 | The Research Foundation For The State University Of New York | Nanoparticle sensor having a nanofibrous membrane scaffold |
| EP3688010A4 (en) * | 2017-09-25 | 2021-08-18 | The Trustees of Columbia University in the City of New York | SEROLOGICAL ASSAY FOR THE DETECTION OF EXPOSURE TO AND INFECTION BY TICKS-CARRIED PATHOGENIC AGENTS |
| CN109596824A (zh) * | 2019-01-04 | 2019-04-09 | 杭州奥泰生物技术股份有限公司 | 一种快速诊断莱姆病的检测试纸及其制备方法 |
| US10928394B2 (en) | 2019-02-07 | 2021-02-23 | Julian R. K. Kage | Rapid test for lyme bacteria |
| CN111018998B (zh) * | 2019-12-04 | 2021-10-29 | 杭州傲锐生物医药科技有限公司 | 一种莱姆重组融合蛋白OspC-VlsE及其应用 |
| JP2022165900A (ja) * | 2021-04-20 | 2022-11-01 | 株式会社デンソー | 分析方法 |
| EP4220166A1 (en) * | 2022-02-01 | 2023-08-02 | Universitat Rovira I Virgili (URV) | In vitro method for detecting antibodies in a sample |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4366246A (en) | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
| US4888276A (en) | 1986-06-26 | 1989-12-19 | Minnesota Mining And Manufacturing Company | Method and composition for the diagnosis of Lyme disease |
| US4721617A (en) | 1986-08-14 | 1988-01-26 | Regents Of The University Of Minnesota | Vaccine against lyme disease |
| US5385826A (en) | 1989-04-21 | 1995-01-31 | Gundersen Medical Foundation, Ltd. | Diagnostic assay for lyme disease |
| DE4015911A1 (de) | 1989-09-19 | 1991-03-28 | Max Planck Gesellschaft | Impfstoff gegen die lyme-krankheit |
| US5187065A (en) | 1989-12-22 | 1993-02-16 | Schutzer Steven E | Method and materials for detecting lyme disease |
| SG122738A1 (en) | 1990-06-15 | 2006-06-29 | Univ Yale | Compositions and methods for the prevention and diagnosis of lyme disease |
| US5155022A (en) | 1991-02-08 | 1992-10-13 | Becton, Dickinson And Company | Assay for lyme disease |
| US5324630A (en) | 1991-06-28 | 1994-06-28 | The Regents Of The University Of California | Methods and compositions for diagnosing lyme disease |
| US6221363B1 (en) | 1991-07-11 | 2001-04-24 | Baxter Aktiengesellschaft | Vaccine for the prevention of lyme disease |
| WO1993003184A1 (en) | 1991-08-09 | 1993-02-18 | Mccann Associates, Inc. | Method for detecting lyme disease and composition |
| US5965702A (en) | 1991-10-21 | 1999-10-12 | Abbott Laboratories | Borrelia burgdorferi antigens and uses thereof |
| US5618533A (en) | 1992-02-11 | 1997-04-08 | Yale University | Flagellin-based polypeptides for the diagnosis of lyme disease |
| US5308753A (en) | 1992-02-20 | 1994-05-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods for purifying and detecting IGM antibodies |
| US5620862A (en) | 1993-11-24 | 1997-04-15 | University Of Connecticut | Methods for diagnosing early Lyme disease |
| US5618333A (en) | 1995-03-28 | 1997-04-08 | Buchholz, Jr.; Leroy H. | Method for volatile organic compound recycling |
| US5932220A (en) | 1995-05-08 | 1999-08-03 | Board Of Regents University Of Texas System | Diagnostic tests for a new spirochete, Borrelia lonestari sp. nov. |
| EP0894143B2 (en) | 1996-02-21 | 2012-04-18 | Board Of Regents, The University Of Texas System | Vmp-like sequences of pathogenic borrelia |
| US6716574B2 (en) | 1996-05-02 | 2004-04-06 | Dako A/S | Osp-C derived peptide fragments |
| US6902893B1 (en) | 1997-06-20 | 2005-06-07 | Gil H. Choi | Lyme disease vaccines |
| ES2270523T3 (es) | 1997-06-30 | 2007-04-01 | The Administrators Of The Tulane Educational Fund | Antigenos de superficie y proteinas utiles en composiciones para la diagnosis y prevencion de la enfermedad de lyme. |
| US6667038B1 (en) | 1999-04-21 | 2003-12-23 | Boston Medical Center Corp. | Prevention, diagnosis and treatment of lyme disease |
| US6475492B1 (en) | 1999-04-28 | 2002-11-05 | The Administrators Of The Tulane Educational Fund | Peptides and assays for the diagnosis of lyme disease |
| US6665652B1 (en) | 1999-07-28 | 2003-12-16 | Richard B. Porwancher | Method of diagnosis of lyme disease |
| US20030129680A1 (en) | 2001-10-31 | 2003-07-10 | O'connor Thomas Patrick | Multi-analyte assay device |
| CA2446246A1 (en) | 2001-05-03 | 2002-11-14 | Immunetics, Inc. | Systems and methods for detection of analytes in biological fluids |
| US6838247B2 (en) | 2002-06-19 | 2005-01-04 | Bowen Research And Training | Test for lyme disease |
| EP2292762A3 (en) | 2002-12-20 | 2012-12-12 | Board of Regents, The University of Texas System | VMP-like sequences of pathogenic Borrelia species and strains |
| US20060046310A1 (en) | 2004-08-25 | 2006-03-02 | Zong-Li Xia | Amplification method for solid phase immunoassays |
| US7390626B2 (en) | 2005-02-25 | 2008-06-24 | Immunosciences Lab., Inc. | Methods and kit for diagnosing tick borne illnesses |
| US8232045B2 (en) | 2005-03-29 | 2012-07-31 | Inverness Medical Switzerland Gmbh | Colloidal metal conjugates |
| WO2007133623A2 (en) | 2006-05-10 | 2007-11-22 | Biopeptides Corporation | Peptide diagnostic agent for lyme disease |
| US7776618B2 (en) | 2007-03-01 | 2010-08-17 | Church & Dwight Co., Inc. | Diagnostic detection device |
| US8399261B2 (en) | 2007-06-27 | 2013-03-19 | Inbios International, Inc. | Lateral flow assay system and methods for its use |
| EP2058663A1 (en) | 2007-11-12 | 2009-05-13 | Euro-Diagnostica B.V. | Method for the immobilization of an analyte on a solid support |
| JP2009236685A (ja) | 2008-03-27 | 2009-10-15 | Sysmex Corp | クロマトグラフィー用試験具 |
| WO2011063003A2 (en) * | 2009-11-17 | 2011-05-26 | Abaxis, Inc. | Peptides and methods for the detection of lyme disease antibodies |
| US8758772B2 (en) | 2011-11-04 | 2014-06-24 | Abaxis, Inc. | Peptides and methods for the detection of lyme disease antibodies |
-
2012
- 2012-11-02 US US13/667,909 patent/US8758772B2/en active Active
- 2012-11-05 FI FIEP19150770.6T patent/FI3502125T3/fi active
- 2012-11-05 ES ES19150770T patent/ES2967710T3/es active Active
- 2012-11-05 EP EP19150770.6A patent/EP3502125B1/en active Active
- 2012-11-05 WO PCT/US2012/063594 patent/WO2013067524A1/en not_active Ceased
- 2012-11-05 EP EP23206262.0A patent/EP4296673A3/en not_active Withdrawn
- 2012-11-05 KR KR1020197035277A patent/KR102503883B1/ko active Active
- 2012-11-05 KR KR1020237006043A patent/KR20230035134A/ko not_active Ceased
- 2012-11-05 KR KR1020147015224A patent/KR20140091735A/ko not_active Ceased
- 2012-11-05 CN CN201280062344.4A patent/CN103998459A/zh active Pending
- 2012-11-05 JP JP2014540187A patent/JP6839485B2/ja active Active
- 2012-11-05 EP EP12846033.4A patent/EP2773654A4/en not_active Ceased
- 2012-11-05 CA CA2851540A patent/CA2851540C/en active Active
- 2012-11-05 DK DK19150770.6T patent/DK3502125T5/da active
- 2012-11-05 PL PL19150770.6T patent/PL3502125T3/pl unknown
-
2014
- 2014-06-13 US US14/304,809 patent/US9201071B2/en active Active
-
2015
- 2015-10-27 US US14/924,358 patent/US9766238B2/en active Active
-
2017
- 2017-08-23 US US15/684,635 patent/US10073095B2/en active Active
-
2018
- 2018-09-10 US US16/126,419 patent/US10921321B2/en active Active
- 2018-10-09 JP JP2018190592A patent/JP2019048811A/ja active Pending
-
2020
- 2020-09-25 JP JP2020160834A patent/JP2021004251A/ja not_active Withdrawn
-
2021
- 2021-01-14 US US17/149,227 patent/US11573227B2/en active Active
-
2023
- 2023-01-03 US US18/149,612 patent/US20230228747A1/en not_active Abandoned
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