JP2013510861A5 - - Google Patents
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- Publication number
- JP2013510861A5 JP2013510861A5 JP2012538954A JP2012538954A JP2013510861A5 JP 2013510861 A5 JP2013510861 A5 JP 2013510861A5 JP 2012538954 A JP2012538954 A JP 2012538954A JP 2012538954 A JP2012538954 A JP 2012538954A JP 2013510861 A5 JP2013510861 A5 JP 2013510861A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- antibiotics
- active agent
- antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims description 16
- 239000003242 anti bacterial agent Substances 0.000 claims description 15
- 229940121375 antifungal agent Drugs 0.000 claims description 12
- 229940088710 antibiotic agent Drugs 0.000 claims description 11
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims description 11
- 239000013543 active substance Substances 0.000 claims description 10
- 239000003429 antifungal agent Substances 0.000 claims description 10
- 230000003115 biocidal effect Effects 0.000 claims description 10
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims description 10
- VVJKKWFAADXIJK-UHFFFAOYSA-N Allylamine Chemical group NCC=C VVJKKWFAADXIJK-UHFFFAOYSA-N 0.000 claims description 8
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 claims description 6
- 229960001259 diclofenac Drugs 0.000 claims description 6
- 150000002632 lipids Chemical class 0.000 claims description 6
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical group C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 claims description 6
- 229960002722 terbinafine Drugs 0.000 claims description 6
- 210000000613 ear canal Anatomy 0.000 claims description 3
- OTVAEFIXJLOWRX-NXEZZACHSA-N thiamphenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl)C=C1 OTVAEFIXJLOWRX-NXEZZACHSA-N 0.000 claims description 3
- 229960003053 thiamphenicol Drugs 0.000 claims description 3
- 229930186147 Cephalosporin Natural products 0.000 claims description 2
- 229930182555 Penicillin Natural products 0.000 claims description 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 2
- 229940035676 analgesics Drugs 0.000 claims description 2
- 229940035674 anesthetics Drugs 0.000 claims description 2
- 239000000730 antalgic agent Substances 0.000 claims description 2
- 230000002141 anti-parasite Effects 0.000 claims description 2
- -1 antifungals Substances 0.000 claims description 2
- 229940125687 antiparasitic agent Drugs 0.000 claims description 2
- 239000003096 antiparasitic agent Substances 0.000 claims description 2
- 239000003443 antiviral agent Substances 0.000 claims description 2
- 229940121357 antivirals Drugs 0.000 claims description 2
- 239000003781 beta lactamase inhibitor Substances 0.000 claims description 2
- 229940126813 beta-lactamase inhibitor Drugs 0.000 claims description 2
- 229940124587 cephalosporin Drugs 0.000 claims description 2
- 150000001780 cephalosporins Chemical class 0.000 claims description 2
- 239000003193 general anesthetic agent Substances 0.000 claims description 2
- 239000003120 macrolide antibiotic agent Substances 0.000 claims description 2
- 229940049954 penicillin Drugs 0.000 claims description 2
- 239000003755 preservative agent Substances 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 claims description 2
- 150000003431 steroids Chemical class 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 16
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 206010033072 otitis externa Diseases 0.000 claims 1
- 230000003637 steroidlike Effects 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- 229940126085 β‑Lactamase Inhibitor Drugs 0.000 claims 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26030909P | 2009-11-11 | 2009-11-11 | |
| US61/260,309 | 2009-11-11 | ||
| PCT/US2010/056255 WO2011060083A1 (en) | 2009-11-11 | 2010-11-10 | Methods and compositions for rapid treatment of otitis externa |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015222609A Division JP6138891B2 (ja) | 2009-11-11 | 2015-11-13 | 外耳炎の迅速な治療のための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013510861A JP2013510861A (ja) | 2013-03-28 |
| JP2013510861A5 true JP2013510861A5 (enExample) | 2013-08-22 |
Family
ID=43992011
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012538954A Pending JP2013510861A (ja) | 2009-11-11 | 2010-11-10 | 外耳炎の迅速な治療のための方法および組成物 |
| JP2015222609A Active JP6138891B2 (ja) | 2009-11-11 | 2015-11-13 | 外耳炎の迅速な治療のための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015222609A Active JP6138891B2 (ja) | 2009-11-11 | 2015-11-13 | 外耳炎の迅速な治療のための方法および組成物 |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8927006B2 (enExample) |
| EP (1) | EP2498792B1 (enExample) |
| JP (2) | JP2013510861A (enExample) |
| KR (2) | KR20120116398A (enExample) |
| CN (1) | CN102612372B (enExample) |
| AU (1) | AU2010319538B2 (enExample) |
| BR (1) | BR112012011017A2 (enExample) |
| CA (1) | CA2780160C (enExample) |
| CL (1) | CL2012001227A1 (enExample) |
| CO (1) | CO6540004A2 (enExample) |
| DK (1) | DK2498792T3 (enExample) |
| EC (1) | ECSP12011967A (enExample) |
| ES (1) | ES2645200T3 (enExample) |
| HR (1) | HRP20171520T1 (enExample) |
| HU (1) | HUE034617T2 (enExample) |
| IL (1) | IL219483A (enExample) |
| LT (1) | LT2498792T (enExample) |
| MX (1) | MX2012005521A (enExample) |
| MY (1) | MY162687A (enExample) |
| NO (1) | NO2498792T3 (enExample) |
| NZ (1) | NZ599559A (enExample) |
| PH (1) | PH12012500913A1 (enExample) |
| PL (1) | PL2498792T3 (enExample) |
| PT (1) | PT2498792T (enExample) |
| RU (1) | RU2680137C2 (enExample) |
| SI (1) | SI2498792T1 (enExample) |
| UA (1) | UA111147C2 (enExample) |
| WO (1) | WO2011060083A1 (enExample) |
| ZA (1) | ZA201203239B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014036165A1 (en) * | 2012-08-29 | 2014-03-06 | Bayer Healthcare, Llc | Aqueous based compositions for treating otitis externa |
| CN104337952A (zh) * | 2013-08-10 | 2015-02-11 | 李谊 | 一种中西医结合治疗爆震性耳聋的组合药物 |
| CN104739768A (zh) * | 2013-12-27 | 2015-07-01 | 河南惠通天下生物工程有限公司 | 一种甲砜霉素纳米脂质体及其制备方法 |
| US11779538B2 (en) | 2017-11-14 | 2023-10-10 | Profem Gmbh | Emulsions for treating mucous membrane infections |
| EP3482744A1 (de) * | 2017-11-14 | 2019-05-15 | ProFem GmbH | Emulsionen zur topischen behandlung urogenitaler und dermaler infektionen |
| BR112022005354A2 (pt) * | 2019-09-23 | 2022-08-23 | Dds Res Inc | Composições de vesícula lipídica com agentes potencializadores de penetração |
| EP4041153A4 (en) * | 2019-10-11 | 2023-10-25 | Piedmont Animal Health Inc. | OTIC FORMULATIONS, METHODS AND DEVICES |
| CA3213099A1 (en) | 2021-03-24 | 2022-09-29 | Robert A. Love | Peptides and methods for reducing skin pigmentation |
| CN113876658B (zh) * | 2021-11-01 | 2023-10-20 | 仙乐健康科技股份有限公司 | 水包油型乳液组合物及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU691249B2 (en) | 1994-02-04 | 1998-05-14 | Lipocore Holding Ab | Bilayer preparations |
| AU3609795A (en) * | 1994-10-10 | 1996-05-02 | Novartis Ag | Ophthalmic and aural compositions containing diclofenac potassium |
| WO1996039146A1 (en) * | 1995-06-06 | 1996-12-12 | Bayer Corporation | Non-irritation, non-sensitizing, non-ototoxic otic antibacterial compositions |
| IT1295369B1 (it) * | 1997-10-21 | 1999-05-12 | Fatro Spa | Composizione a base di tiamfenicolo e diclofenac |
| US6433024B1 (en) * | 2000-05-08 | 2002-08-13 | Karl F. Popp | Topical anti-acne composition |
| AUPR798901A0 (en) * | 2001-09-28 | 2001-10-25 | Medvet Science Pty. Ltd. | Spheroidal hdl particles with a defined phospholipid composition |
| US20080206161A1 (en) * | 2002-10-25 | 2008-08-28 | Dov Tamarkin | Quiescent foamable compositions, steroids, kits and uses thereof |
| US20050013854A1 (en) * | 2003-04-09 | 2005-01-20 | Mannino Raphael J. | Novel encochleation methods, cochleates and methods of use |
| JP2007500691A (ja) * | 2003-07-31 | 2007-01-18 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 抗炎症剤の分散性製剤 |
| US20070054844A1 (en) * | 2003-08-20 | 2007-03-08 | Fairfield Clinical Trials, Llc | Method for treating otitis externa |
| US20070078116A1 (en) | 2003-08-20 | 2007-04-05 | Fairfield Clinical Trials, Llc | Method of treatment of otitis externa |
| US20050159369A1 (en) * | 2003-08-20 | 2005-07-21 | Qtm Llc | Method of treatment of otitis externa |
| US20080124385A1 (en) | 2004-09-03 | 2008-05-29 | Piedmont Pharmaceuticals,Llc. | Methods for Transmembrane Treatment and Prevention of Otitis Media |
| TW200719884A (en) | 2005-03-10 | 2007-06-01 | 3M Innovative Properties Co | Methods of treating ear infections |
| US20090082337A1 (en) | 2007-09-21 | 2009-03-26 | Srini Venkastesh | Compositions Comprising Quinolone and Methods for Treating or Controlling Infections |
| US20090111780A1 (en) * | 2007-10-31 | 2009-04-30 | Everett Laboratories, Inc. | Compositions and methods for treatment of ear canal infection and inflammation |
-
2010
- 2010-10-11 UA UAA201207023A patent/UA111147C2/uk unknown
- 2010-11-10 EP EP10830669.7A patent/EP2498792B1/en active Active
- 2010-11-10 LT LTEP10830669.7T patent/LT2498792T/lt unknown
- 2010-11-10 PH PH1/2012/500913A patent/PH12012500913A1/en unknown
- 2010-11-10 HU HUE10830669A patent/HUE034617T2/en unknown
- 2010-11-10 CA CA2780160A patent/CA2780160C/en active Active
- 2010-11-10 US US12/943,810 patent/US8927006B2/en active Active
- 2010-11-10 RU RU2012124067A patent/RU2680137C2/ru active
- 2010-11-10 WO PCT/US2010/056255 patent/WO2011060083A1/en not_active Ceased
- 2010-11-10 AU AU2010319538A patent/AU2010319538B2/en active Active
- 2010-11-10 SI SI201031550T patent/SI2498792T1/sl unknown
- 2010-11-10 PL PL10830669T patent/PL2498792T3/pl unknown
- 2010-11-10 HR HRP20171520TT patent/HRP20171520T1/hr unknown
- 2010-11-10 DK DK10830669.7T patent/DK2498792T3/da active
- 2010-11-10 MX MX2012005521A patent/MX2012005521A/es active IP Right Grant
- 2010-11-10 JP JP2012538954A patent/JP2013510861A/ja active Pending
- 2010-11-10 CN CN201080051245.7A patent/CN102612372B/zh active Active
- 2010-11-10 NZ NZ599559A patent/NZ599559A/en unknown
- 2010-11-10 PT PT108306697T patent/PT2498792T/pt unknown
- 2010-11-10 KR KR1020127013348A patent/KR20120116398A/ko not_active Ceased
- 2010-11-10 MY MYPI2012001989A patent/MY162687A/en unknown
- 2010-11-10 BR BR112012011017A patent/BR112012011017A2/pt not_active Application Discontinuation
- 2010-11-10 NO NO10830669A patent/NO2498792T3/no unknown
- 2010-11-10 KR KR1020177023631A patent/KR101901083B1/ko active Active
- 2010-11-10 ES ES10830669.7T patent/ES2645200T3/es active Active
-
2012
- 2012-04-30 IL IL219483A patent/IL219483A/en active IP Right Grant
- 2012-05-04 ZA ZA2012/03239A patent/ZA201203239B/en unknown
- 2012-05-10 CL CL2012001227A patent/CL2012001227A1/es unknown
- 2012-06-01 CO CO12092192A patent/CO6540004A2/es unknown
- 2012-06-11 EC ECSP12011967 patent/ECSP12011967A/es unknown
-
2015
- 2015-11-13 JP JP2015222609A patent/JP6138891B2/ja active Active
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