CL2012001227A1 - Composicion farmaceutica que comprende un portador de lipidos y al menos dos agentes activos selccionados entre antibioticos, antihongos, antiparasitarios, antivirales, antinflamatorios no esteroideos, analgesicos, anestesicos y esteroides; donde el portador lipidico es una emulsion lipidicadea aceite en agua, una microemulsion lipidica o una vesicula lipidica; uso en la infeccion por otitis externa. - Google Patents
Composicion farmaceutica que comprende un portador de lipidos y al menos dos agentes activos selccionados entre antibioticos, antihongos, antiparasitarios, antivirales, antinflamatorios no esteroideos, analgesicos, anestesicos y esteroides; donde el portador lipidico es una emulsion lipidicadea aceite en agua, una microemulsion lipidica o una vesicula lipidica; uso en la infeccion por otitis externa.Info
- Publication number
- CL2012001227A1 CL2012001227A1 CL2012001227A CL2012001227A CL2012001227A1 CL 2012001227 A1 CL2012001227 A1 CL 2012001227A1 CL 2012001227 A CL2012001227 A CL 2012001227A CL 2012001227 A CL2012001227 A CL 2012001227A CL 2012001227 A1 CL2012001227 A1 CL 2012001227A1
- Authority
- CL
- Chile
- Prior art keywords
- lipid
- carrier
- infection
- pharmaceutical composition
- active agents
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 5
- 239000013543 active substance Substances 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 206010033072 otitis externa Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000003444 anaesthetic effect Effects 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 230000002141 anti-parasite Effects 0.000 title 1
- 230000000840 anti-viral effect Effects 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- -1 antifungal Substances 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- 239000003096 antiparasitic agent Substances 0.000 title 1
- 239000002960 lipid emulsion Substances 0.000 title 1
- 239000004530 micro-emulsion Substances 0.000 title 1
- 230000003637 steroidlike Effects 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26030909P | 2009-11-11 | 2009-11-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012001227A1 true CL2012001227A1 (es) | 2012-08-24 |
Family
ID=43992011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012001227A CL2012001227A1 (es) | 2009-11-11 | 2012-05-10 | Composicion farmaceutica que comprende un portador de lipidos y al menos dos agentes activos selccionados entre antibioticos, antihongos, antiparasitarios, antivirales, antinflamatorios no esteroideos, analgesicos, anestesicos y esteroides; donde el portador lipidico es una emulsion lipidicadea aceite en agua, una microemulsion lipidica o una vesicula lipidica; uso en la infeccion por otitis externa. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8927006B2 (enExample) |
| EP (1) | EP2498792B1 (enExample) |
| JP (2) | JP2013510861A (enExample) |
| KR (2) | KR20120116398A (enExample) |
| CN (1) | CN102612372B (enExample) |
| AU (1) | AU2010319538B2 (enExample) |
| BR (1) | BR112012011017A2 (enExample) |
| CA (1) | CA2780160C (enExample) |
| CL (1) | CL2012001227A1 (enExample) |
| CO (1) | CO6540004A2 (enExample) |
| DK (1) | DK2498792T3 (enExample) |
| EC (1) | ECSP12011967A (enExample) |
| ES (1) | ES2645200T3 (enExample) |
| HR (1) | HRP20171520T1 (enExample) |
| HU (1) | HUE034617T2 (enExample) |
| IL (1) | IL219483A (enExample) |
| LT (1) | LT2498792T (enExample) |
| MX (1) | MX2012005521A (enExample) |
| MY (1) | MY162687A (enExample) |
| NO (1) | NO2498792T3 (enExample) |
| NZ (1) | NZ599559A (enExample) |
| PH (1) | PH12012500913A1 (enExample) |
| PL (1) | PL2498792T3 (enExample) |
| PT (1) | PT2498792T (enExample) |
| RU (1) | RU2680137C2 (enExample) |
| SI (1) | SI2498792T1 (enExample) |
| UA (1) | UA111147C2 (enExample) |
| WO (1) | WO2011060083A1 (enExample) |
| ZA (1) | ZA201203239B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11266600B2 (en) | 2017-11-14 | 2022-03-08 | Profem Gmbh | Emulsions for the topical treatment of dermal and mucosal infections |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014036165A1 (en) * | 2012-08-29 | 2014-03-06 | Bayer Healthcare, Llc | Aqueous based compositions for treating otitis externa |
| CN104337952A (zh) * | 2013-08-10 | 2015-02-11 | 李谊 | 一种中西医结合治疗爆震性耳聋的组合药物 |
| CN104739768A (zh) * | 2013-12-27 | 2015-07-01 | 河南惠通天下生物工程有限公司 | 一种甲砜霉素纳米脂质体及其制备方法 |
| EP3482744A1 (de) * | 2017-11-14 | 2019-05-15 | ProFem GmbH | Emulsionen zur topischen behandlung urogenitaler und dermaler infektionen |
| BR112022005354A2 (pt) * | 2019-09-23 | 2022-08-23 | Dds Res Inc | Composições de vesícula lipídica com agentes potencializadores de penetração |
| EP4041153A4 (en) * | 2019-10-11 | 2023-10-25 | Piedmont Animal Health Inc. | OTIC FORMULATIONS, METHODS AND DEVICES |
| CA3213099A1 (en) | 2021-03-24 | 2022-09-29 | Robert A. Love | Peptides and methods for reducing skin pigmentation |
| CN113876658B (zh) * | 2021-11-01 | 2023-10-20 | 仙乐健康科技股份有限公司 | 水包油型乳液组合物及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU691249B2 (en) | 1994-02-04 | 1998-05-14 | Lipocore Holding Ab | Bilayer preparations |
| AU3609795A (en) * | 1994-10-10 | 1996-05-02 | Novartis Ag | Ophthalmic and aural compositions containing diclofenac potassium |
| WO1996039146A1 (en) * | 1995-06-06 | 1996-12-12 | Bayer Corporation | Non-irritation, non-sensitizing, non-ototoxic otic antibacterial compositions |
| IT1295369B1 (it) * | 1997-10-21 | 1999-05-12 | Fatro Spa | Composizione a base di tiamfenicolo e diclofenac |
| US6433024B1 (en) * | 2000-05-08 | 2002-08-13 | Karl F. Popp | Topical anti-acne composition |
| AUPR798901A0 (en) * | 2001-09-28 | 2001-10-25 | Medvet Science Pty. Ltd. | Spheroidal hdl particles with a defined phospholipid composition |
| US20080206161A1 (en) * | 2002-10-25 | 2008-08-28 | Dov Tamarkin | Quiescent foamable compositions, steroids, kits and uses thereof |
| US20050013854A1 (en) * | 2003-04-09 | 2005-01-20 | Mannino Raphael J. | Novel encochleation methods, cochleates and methods of use |
| JP2007500691A (ja) * | 2003-07-31 | 2007-01-18 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 抗炎症剤の分散性製剤 |
| US20070054844A1 (en) * | 2003-08-20 | 2007-03-08 | Fairfield Clinical Trials, Llc | Method for treating otitis externa |
| US20070078116A1 (en) | 2003-08-20 | 2007-04-05 | Fairfield Clinical Trials, Llc | Method of treatment of otitis externa |
| US20050159369A1 (en) * | 2003-08-20 | 2005-07-21 | Qtm Llc | Method of treatment of otitis externa |
| US20080124385A1 (en) | 2004-09-03 | 2008-05-29 | Piedmont Pharmaceuticals,Llc. | Methods for Transmembrane Treatment and Prevention of Otitis Media |
| TW200719884A (en) | 2005-03-10 | 2007-06-01 | 3M Innovative Properties Co | Methods of treating ear infections |
| US20090082337A1 (en) | 2007-09-21 | 2009-03-26 | Srini Venkastesh | Compositions Comprising Quinolone and Methods for Treating or Controlling Infections |
| US20090111780A1 (en) * | 2007-10-31 | 2009-04-30 | Everett Laboratories, Inc. | Compositions and methods for treatment of ear canal infection and inflammation |
-
2010
- 2010-10-11 UA UAA201207023A patent/UA111147C2/uk unknown
- 2010-11-10 EP EP10830669.7A patent/EP2498792B1/en active Active
- 2010-11-10 LT LTEP10830669.7T patent/LT2498792T/lt unknown
- 2010-11-10 PH PH1/2012/500913A patent/PH12012500913A1/en unknown
- 2010-11-10 HU HUE10830669A patent/HUE034617T2/en unknown
- 2010-11-10 CA CA2780160A patent/CA2780160C/en active Active
- 2010-11-10 US US12/943,810 patent/US8927006B2/en active Active
- 2010-11-10 RU RU2012124067A patent/RU2680137C2/ru active
- 2010-11-10 WO PCT/US2010/056255 patent/WO2011060083A1/en not_active Ceased
- 2010-11-10 AU AU2010319538A patent/AU2010319538B2/en active Active
- 2010-11-10 SI SI201031550T patent/SI2498792T1/sl unknown
- 2010-11-10 PL PL10830669T patent/PL2498792T3/pl unknown
- 2010-11-10 HR HRP20171520TT patent/HRP20171520T1/hr unknown
- 2010-11-10 DK DK10830669.7T patent/DK2498792T3/da active
- 2010-11-10 MX MX2012005521A patent/MX2012005521A/es active IP Right Grant
- 2010-11-10 JP JP2012538954A patent/JP2013510861A/ja active Pending
- 2010-11-10 CN CN201080051245.7A patent/CN102612372B/zh active Active
- 2010-11-10 NZ NZ599559A patent/NZ599559A/en unknown
- 2010-11-10 PT PT108306697T patent/PT2498792T/pt unknown
- 2010-11-10 KR KR1020127013348A patent/KR20120116398A/ko not_active Ceased
- 2010-11-10 MY MYPI2012001989A patent/MY162687A/en unknown
- 2010-11-10 BR BR112012011017A patent/BR112012011017A2/pt not_active Application Discontinuation
- 2010-11-10 NO NO10830669A patent/NO2498792T3/no unknown
- 2010-11-10 KR KR1020177023631A patent/KR101901083B1/ko active Active
- 2010-11-10 ES ES10830669.7T patent/ES2645200T3/es active Active
-
2012
- 2012-04-30 IL IL219483A patent/IL219483A/en active IP Right Grant
- 2012-05-04 ZA ZA2012/03239A patent/ZA201203239B/en unknown
- 2012-05-10 CL CL2012001227A patent/CL2012001227A1/es unknown
- 2012-06-01 CO CO12092192A patent/CO6540004A2/es unknown
- 2012-06-11 EC ECSP12011967 patent/ECSP12011967A/es unknown
-
2015
- 2015-11-13 JP JP2015222609A patent/JP6138891B2/ja active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11266600B2 (en) | 2017-11-14 | 2022-03-08 | Profem Gmbh | Emulsions for the topical treatment of dermal and mucosal infections |
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