JP2013510581A5 - - Google Patents
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- JP2013510581A5 JP2013510581A5 JP2012539007A JP2012539007A JP2013510581A5 JP 2013510581 A5 JP2013510581 A5 JP 2013510581A5 JP 2012539007 A JP2012539007 A JP 2012539007A JP 2012539007 A JP2012539007 A JP 2012539007A JP 2013510581 A5 JP2013510581 A5 JP 2013510581A5
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- Prior art keywords
- acid sequence
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26114509P | 2009-11-13 | 2009-11-13 | |
| US61/261,145 | 2009-11-13 | ||
| PCT/US2010/056496 WO2011060242A2 (en) | 2009-11-13 | 2010-11-12 | Von willebrand factor (vwf)-containing preparations, and methods, kits, and uses related thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013510581A JP2013510581A (ja) | 2013-03-28 |
| JP2013510581A5 true JP2013510581A5 (enExample) | 2013-11-14 |
| JP5876416B2 JP5876416B2 (ja) | 2016-03-02 |
Family
ID=43992414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012539007A Active JP5876416B2 (ja) | 2009-11-13 | 2010-11-12 | フォンウィルブランド因子（ｖＷＦ）含有調製品並びにこれに関連する方法、キット及び使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8759293B2 (enExample) |
| EP (1) | EP2499165B1 (enExample) |
| JP (1) | JP5876416B2 (enExample) |
| KR (1) | KR101808751B1 (enExample) |
| CN (1) | CN102648212B (enExample) |
| AU (1) | AU2010319425B2 (enExample) |
| BR (1) | BR112012011740A2 (enExample) |
| CA (1) | CA2780542C (enExample) |
| CL (1) | CL2012001258A1 (enExample) |
| ES (1) | ES2600879T3 (enExample) |
| HU (1) | HUE029454T2 (enExample) |
| IL (1) | IL219679A (enExample) |
| MX (1) | MX2012005527A (enExample) |
| NZ (1) | NZ600278A (enExample) |
| PL (1) | PL2499165T3 (enExample) |
| PT (1) | PT2499165T (enExample) |
| RU (1) | RU2579977C2 (enExample) |
| WO (1) | WO2011060242A2 (enExample) |
| ZA (1) | ZA201203795B (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6263355A (ja) * | 1985-09-13 | 1987-03-20 | Hitachi Ltd | バツテリバツクアツプｒａｍのチエツク方法 |
| MX367012B (es) | 2007-06-01 | 2019-08-02 | Univ Maryland | Agentes de union al receptor de la region constante fc de inmunoglobulina. |
| US20110046060A1 (en) | 2009-08-24 | 2011-02-24 | Amunix Operating, Inc., | Coagulation factor IX compositions and methods of making and using same |
| HUE029454T2 (en) | 2009-11-13 | 2017-03-28 | Grifols Therapeutics Inc | Von willebrand factor (vwf)-containing preparations, and methods, kits, and uses related thereto |
| AU2011282579B2 (en) | 2010-07-28 | 2014-10-23 | Gliknik Inc. | Fusion proteins of natural human protein fragments to create orderly multimerized immunoglobulin Fc compositions |
| WO2013098676A1 (en) | 2011-12-30 | 2013-07-04 | Grifols, S.A. | Method for purifying factor viii |
| CN111499761A (zh) * | 2012-01-12 | 2020-08-07 | 比奥贝拉蒂治疗公司 | 嵌合因子viii多肽及其用途 |
| BR112014017111A8 (pt) | 2012-01-12 | 2018-05-15 | Biogen Idec Inc | métodos de redução de imunogenicidade contra o fator viii em indivíduos submetidos à terapia de fator viii |
| NZ628014A (en) | 2012-02-15 | 2016-09-30 | Biogen Ma Inc | Recombinant factor viii proteins |
| CN111548418A (zh) | 2012-02-15 | 2020-08-18 | 比奥贝拉蒂治疗公司 | 因子viii组合物及其制备和使用方法 |
| US20150080309A1 (en) | 2012-04-24 | 2015-03-19 | Nova Nordisk A/S | Compounds Suitable for Treatment of Haemophilia |
| AU2013290173B2 (en) * | 2012-07-11 | 2018-02-15 | Bioverativ Therapeutics Inc. | Factor VIII complex with XTEN and von Willebrand Factor protein, and uses thereof |
| EP2885320A4 (en) | 2012-08-20 | 2016-04-06 | Gliknik Inc | MOLECULES WITH ANTIGEN-BINDING AND POLYVALENT FC GAMMA RECEPTOR BINDING ACTIVITY |
| BR112015009229B1 (pt) * | 2012-10-24 | 2021-07-20 | Platelet Targeted Therapeutics, Llc | Composição tendo como alvo a expressão de genes para plaquetas, uso de uma célula tronco compreendendo a referida composição para tratar hemofilia e método in vitro ou ex vivo para gerar uma célula tronco modificada |
| GB201304973D0 (en) * | 2013-03-19 | 2013-05-01 | Profactor Pharma Ltd | Recombinant protein |
| ES2657291T3 (es) | 2013-04-22 | 2018-03-02 | Csl Ltd. | Un complejo covalente de factor de von Willebrand y factor VIII asociado por un puente disulfuro |
| CN105452289A (zh) * | 2013-06-12 | 2016-03-30 | 诺和诺德股份有限公司 | 适用于治疗血友病的化合物 |
| HK1223302A1 (zh) * | 2013-06-28 | 2017-07-28 | Bioverativ Therapeutics Inc. | 具有xten的凝血酶可裂解连接子和其用途 |
| EP3013359A4 (en) * | 2013-06-28 | 2017-01-25 | Biogen MA Inc. | Thrombin cleavable linker |
| EP3043813B1 (en) | 2013-08-08 | 2021-01-13 | Bioverativ Therapeutics Inc. | Purification of chimeric fviii molecules |
| US10548953B2 (en) | 2013-08-14 | 2020-02-04 | Bioverativ Therapeutics Inc. | Factor VIII-XTEN fusions and uses thereof |
| PH12016501323B1 (en) * | 2014-01-10 | 2022-04-29 | Bioverativ Therapeutics Inc | Factor viii chimeric proteins and uses thereof |
| US10626164B2 (en) * | 2014-07-25 | 2020-04-21 | Csl Limited | Purification of VWF |
| US9701933B2 (en) * | 2014-09-19 | 2017-07-11 | Sarfaraz K. Niazi | Harvesting and purification or perfusion yielder (HAPPY) device |
| KR20170125941A (ko) * | 2015-03-06 | 2017-11-15 | 체에스엘 베링 리컴비넌트 퍼실리티 아게 | 개선된 반감기를 갖는 변형된 폰 빌레브란트 인자 |
| EP4089109A3 (en) | 2015-05-22 | 2023-03-01 | CSL Behring Lengnau AG | Methods for preparing modified von willebrand factor |
| BR112017023785A2 (pt) | 2015-05-22 | 2018-07-17 | Csl Behring Recombinant Facility Ag | polipeptídeos do fator de von willebrand truncados para tratar hemofilia |
| FI3325011T6 (fi) | 2015-07-24 | 2023-05-11 | Ihmisen proteiinifragmenttien fuusioproteiineja järjestyksenmukaisesti multimerisoitujen, paremmin komplementtia sitovien immunoglobuliini-fc-koostumusten muodostamiseksi | |
| AU2016301303B2 (en) | 2015-08-03 | 2021-10-07 | Bioverativ Therapeutics Inc. | Factor IX fusion proteins and methods of making and using same |
| DK3400238T3 (da) * | 2016-01-07 | 2021-07-26 | CSL Behring Lengnau AG | Muteret von willebrand faktor |
| RU2018128582A (ru) | 2016-01-07 | 2020-02-11 | Цсл Беринг Ленгнау Аг | Мутированный укороченный фактор фон виллебранда |
| US11034775B2 (en) | 2016-06-07 | 2021-06-15 | Gliknik Inc. | Cysteine-optimized stradomers |
| EP3476937A4 (en) | 2016-06-24 | 2019-12-04 | Mogam Institute for Biomedical Research | CHIMERIC PROTEIN WITH FVIII AND VWF FACTORS AND USE THEREOF |
| SG11201903954WA (en) | 2016-11-11 | 2019-05-30 | CSL Behring Lengnau AG | Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder |
| US11814421B2 (en) | 2016-11-11 | 2023-11-14 | CSL Behring Lengnau AG | Truncated von Willebrand Factor polypeptides for treating hemophilia |
| CN110520149A (zh) | 2016-12-02 | 2019-11-29 | 比奥维拉迪维治疗股份有限公司 | 诱导对凝血因子的免疫耐受性的方法 |
| WO2018102743A1 (en) | 2016-12-02 | 2018-06-07 | Bioverativ Therapeutics Inc. | Methods of treating hemophilic arthropathy using chimeric clotting factors |
| KR102729723B1 (ko) | 2016-12-09 | 2024-11-15 | 글리크닉 인코포레이티드 | 다합체화 스트라도머인 gl-2045의 제조 최적화 |
| JP7519774B2 (ja) | 2016-12-09 | 2024-07-22 | グリックニック インコーポレイテッド | 多価ｆｃ化合物を用いる炎症性疾患の治療方法 |
| EP3612209A4 (en) * | 2017-04-20 | 2021-03-24 | The University of Chicago | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER WITH MEC AFFINITY PEPTIDES RELATED TO IMMUNOTHERAPEUTIC ANTIBODIES |
| GB201707139D0 (en) * | 2017-05-04 | 2017-06-21 | Imp Innovations Ltd | Polypeptides |
| WO2018234518A1 (en) | 2017-06-22 | 2018-12-27 | CSL Behring Lengnau AG | Modulation of fviii immunogenicity by truncated vwf |
| EP3648787B1 (en) * | 2017-07-07 | 2024-10-30 | Takeda Pharmaceutical Company Limited | Treatment of patients with severe von willebrand disease undergoing elective surgery by administration of recombinant vwf |
| CA3081106A1 (en) * | 2017-11-01 | 2019-05-09 | Queen's University At Kingston | Von willebrand factor proteins for treating bleeding disorders |
| WO2019173289A1 (en) | 2018-03-05 | 2019-09-12 | The University Of Chicago | Methods and compositions for treating cancer with ecm-affinity peptides linked to cytokines |
| JP7763589B2 (ja) | 2018-05-18 | 2025-11-04 | バイオベラティブ セラピューティクス インコーポレイテッド | 血友病ａを処置する方法 |
| US10654911B1 (en) * | 2019-04-02 | 2020-05-19 | Beijing Neoletix Biological Technology Co., Ltd. | Vector co-expressing truncated von Willebrand factor and factor VIII |
| AU2020289485A1 (en) * | 2019-06-03 | 2022-02-03 | The University Of Chicago | Methods and compositions for treating cancer with collagen binding drug carriers |
| KR20220029733A (ko) | 2019-07-04 | 2022-03-08 | 체에스엘 베링 렝나우 아게 | 응고 인자 viii의 시험관내 안정성을 증가시키기 위한 절단된 폰 빌레브란트 인자 (vwf) |
| WO2021094344A1 (en) | 2019-11-11 | 2021-05-20 | CSL Behring Lengnau AG | Polypeptides for inducing tolerance to factor viii |
| WO2024106355A1 (ja) * | 2022-11-14 | 2024-05-23 | セルジェンテック株式会社 | 血液凝固第ｖｉｉｉ因子改変体を産生するエクスビボ遺伝子治療用細胞 |
| CN116333081B (zh) * | 2022-12-27 | 2025-09-19 | 大连海洋大学 | 长牡蛎CgVg功能域DUF1943和VWD重组蛋白及应用 |
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-
2010
- 2010-11-12 HU HUE10830777A patent/HUE029454T2/en unknown
- 2010-11-12 NZ NZ600278A patent/NZ600278A/en not_active IP Right Cessation
- 2010-11-12 PL PL10830777T patent/PL2499165T3/pl unknown
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