JP2011182796A5 - - Google Patents
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- Publication number
- JP2011182796A5 JP2011182796A5 JP2011092442A JP2011092442A JP2011182796A5 JP 2011182796 A5 JP2011182796 A5 JP 2011182796A5 JP 2011092442 A JP2011092442 A JP 2011092442A JP 2011092442 A JP2011092442 A JP 2011092442A JP 2011182796 A5 JP2011182796 A5 JP 2011182796A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- fragments
- protein
- generates
- detectable signal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012634 fragment Substances 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46113303P | 2003-04-09 | 2003-04-09 | |
| US60/461,133 | 2003-04-09 | ||
| US10/724,178 US7166424B2 (en) | 1998-02-02 | 2003-12-01 | Fragments of fluorescent proteins for protein fragment complementation assays |
| US10/724,178 | 2003-12-01 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509857A Division JP2006524244A (ja) | 2003-04-09 | 2004-04-09 | タンパク質断片の相補性アッセイのための蛍光タンパク質断片 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011182796A JP2011182796A (ja) | 2011-09-22 |
| JP2011182796A5 true JP2011182796A5 (enExample) | 2012-07-19 |
Family
ID=35385090
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509857A Pending JP2006524244A (ja) | 2003-04-09 | 2004-04-09 | タンパク質断片の相補性アッセイのための蛍光タンパク質断片 |
| JP2011092442A Pending JP2011182796A (ja) | 2003-04-09 | 2011-04-18 | タンパク質断片の相補性アッセイのための蛍光タンパク質断片 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509857A Pending JP2006524244A (ja) | 2003-04-09 | 2004-04-09 | タンパク質断片の相補性アッセイのための蛍光タンパク質断片 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7166424B2 (enExample) |
| EP (2) | EP2317318A1 (enExample) |
| JP (2) | JP2006524244A (enExample) |
| AU (2) | AU2004230600A1 (enExample) |
| CA (1) | CA2522060C (enExample) |
| WO (1) | WO2004092336A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6897017B1 (en) * | 1997-01-31 | 2005-05-24 | Odyssey Thera Inc. | Vivo library-versus-library selection of optimized protein-protein interactions |
| US20020064769A1 (en) * | 2000-10-05 | 2002-05-30 | Watson Michnick Stephen William | Dynamic visualization of expressed gene networks in living cells |
| US7062219B2 (en) * | 1997-01-31 | 2006-06-13 | Odyssey Thera Inc. | Protein fragment complementation assays for high-throughput and high-content screening |
| US20050221280A1 (en) * | 1998-02-02 | 2005-10-06 | Odyssey Thera, Inc. | Protein-protein interactions for pharmacological profiling |
| JP3829252B2 (ja) * | 2001-06-08 | 2006-10-04 | 独立行政法人理化学研究所 | 蛍光蛋白質 |
| WO2005001115A2 (en) * | 2003-05-30 | 2005-01-06 | Odyssey Thera, Inc. | Monitoring gene silencing and annotating gene function in living cells |
| US20070224615A1 (en) * | 2003-07-09 | 2007-09-27 | Invitrogen Corporation | Methods for assaying protein-protein interactions |
| US7488583B2 (en) * | 2003-09-25 | 2009-02-10 | Odyssey Thera, Inc. | Fragment complementation assays for G-protein-coupled receptors and their signaling pathways |
| GB0327143D0 (en) * | 2003-11-21 | 2003-12-24 | Univ Belfast | Assay |
| US20090221440A1 (en) * | 2004-07-12 | 2009-09-03 | Board Of Regents, The University Of Texas System | Methods and compositions related to identifying protein-protein interactions |
| US20060094059A1 (en) * | 2004-09-22 | 2006-05-04 | Odyssey Thera, Inc. | Methods for identifying new drug leads and new therapeutic uses for known drugs |
| US20060094682A1 (en) | 2004-10-29 | 2006-05-04 | Odyssey Thera, Inc. | Kinase inhibitors for the treatment of diabetes and obesity |
| WO2006062877A2 (en) * | 2004-12-04 | 2006-06-15 | The Regents Of The University Of California | Protein subcellular localization assays using split fluorescent proteins |
| US8541558B2 (en) * | 2005-05-03 | 2013-09-24 | Georgia State University Research Foundation, Inc. | Fluorescent proteins and uses thereof |
| EP1931787A4 (en) * | 2005-09-30 | 2010-10-20 | Univ Montana State | SYSTEM FOR DETECTING PROTEIN-PROTEIN INTERACTIONS |
| US20090220942A1 (en) * | 2005-10-27 | 2009-09-03 | Natalia Broude | Activated split-polypeptides and methods for their production and use |
| EP1954828A2 (en) * | 2005-10-27 | 2008-08-13 | The Trustees Of Boston University | Real time nucleic acid detection in vivo using protein complementation |
| US20090170091A1 (en) * | 2006-01-17 | 2009-07-02 | Kenneth Giuliano | Method For Predicting Biological Systems Responses |
| EP1847604A1 (en) | 2006-04-19 | 2007-10-24 | Millegen | Intracellular method for selecting a peptide or polypeptide which binds to a bait peptide or polypeptide |
| US8114615B2 (en) | 2006-05-17 | 2012-02-14 | Cernostics, Inc. | Method for automated tissue analysis |
| WO2008060483A2 (en) * | 2006-11-10 | 2008-05-22 | Cellumen, Inc. | Protein-protein interaction biosensors and methods of use thereof |
| CA2704226A1 (en) * | 2007-11-01 | 2009-05-07 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Cell-free methods for detecting protein-ligand interctions |
| US20100081632A1 (en) * | 2008-03-06 | 2010-04-01 | Odyssey Thera, Inc. | High-content and high throughput assays for identification of lipid-regulating pathways, and novel therapeutic agents for lipid disorders |
| WO2011135040A1 (en) | 2010-04-30 | 2011-11-03 | F. Hoffmann-La Roche Ag | Fluorescent antibody fusion protein, its production and use |
| CN103179940B (zh) | 2010-08-24 | 2016-01-13 | 安全白有限公司 | 提供牙齿洁白外观的方法和材料 |
| US10018631B2 (en) | 2011-03-17 | 2018-07-10 | Cernostics, Inc. | Systems and compositions for diagnosing Barrett's esophagus and methods of using the same |
| WO2015109003A1 (en) | 2014-01-14 | 2015-07-23 | Asedasciences Ag | Identification of functional cell states |
| CA2851568A1 (en) | 2014-05-09 | 2015-11-09 | The Governors Of The University Of Alberta | Drug discovery and protein-protein interaction assay using flourescent protein exchange |
| KR101751917B1 (ko) * | 2016-02-02 | 2017-06-28 | 기초과학연구원 | 가역적으로 활성화 가능한 항체 유사체 및 그의 용도 |
| CN108267595A (zh) * | 2017-11-27 | 2018-07-10 | 南京天纵易康生物科技股份有限公司 | 一种基于双分子荧光互补技术的Myo检测试剂盒、制备及使用方法 |
| CN111718417B (zh) * | 2019-03-19 | 2022-10-14 | 宁波鲲鹏生物科技有限公司 | 含有荧光蛋白片段的融合蛋白及其用途 |
| EP4554964A1 (en) * | 2022-07-11 | 2025-05-21 | Cornell University | Chemically stable fluorescent proteins for advanced microscopy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6294330B1 (en) * | 1997-01-31 | 2001-09-25 | Odyssey Pharmaceuticals Inc. | Protein fragment complementation assays for the detection of biological or drug interactions |
| US7062219B2 (en) * | 1997-01-31 | 2006-06-13 | Odyssey Thera Inc. | Protein fragment complementation assays for high-throughput and high-content screening |
| CA2196496A1 (en) * | 1997-01-31 | 1998-07-31 | Stephen William Watson Michnick | Protein fragment complementation assay for the detection of protein-protein interactions |
| CA2384561A1 (en) * | 2000-05-12 | 2001-11-22 | Yale University | Methods of detecting interactions between proteins, peptides or libraries thereof using fusion proteins |
| WO2003089627A1 (en) * | 2002-04-19 | 2003-10-30 | Bioimage A/S | Translocation dependent complementation for drug screening |
| JP2006506950A (ja) * | 2002-04-19 | 2006-03-02 | バイオイメージ・アクティーゼルスカブ | ２つの緑色蛍光タンパク質断片およびタンパク質−タンパク質の相互作用を検出するための方法におけるこれらの使用 |
-
2003
- 2003-12-01 US US10/724,178 patent/US7166424B2/en not_active Expired - Fee Related
-
2004
- 2004-04-09 EP EP10183931A patent/EP2317318A1/en not_active Withdrawn
- 2004-04-09 EP EP04759337A patent/EP1616186A4/en not_active Withdrawn
- 2004-04-09 AU AU2004230600A patent/AU2004230600A1/en not_active Abandoned
- 2004-04-09 JP JP2006509857A patent/JP2006524244A/ja active Pending
- 2004-04-09 CA CA2522060A patent/CA2522060C/en not_active Expired - Fee Related
- 2004-04-09 WO PCT/US2004/010982 patent/WO2004092336A2/en not_active Ceased
-
2007
- 2007-01-23 US US11/656,543 patent/US8101364B2/en not_active Expired - Fee Related
-
2011
- 2011-03-09 AU AU2011201031A patent/AU2011201031A1/en not_active Abandoned
- 2011-04-18 JP JP2011092442A patent/JP2011182796A/ja active Pending
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