JP2013509423A5 - - Google Patents
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- Publication number
- JP2013509423A5 JP2013509423A5 JP2012537052A JP2012537052A JP2013509423A5 JP 2013509423 A5 JP2013509423 A5 JP 2013509423A5 JP 2012537052 A JP2012537052 A JP 2012537052A JP 2012537052 A JP2012537052 A JP 2012537052A JP 2013509423 A5 JP2013509423 A5 JP 2013509423A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- methyl
- alkyl
- group
- oxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 **(C(NCC#CC(CCCC1)CCC1(*)I)=O)N Chemical compound **(C(NCC#CC(CCCC1)CCC1(*)I)=O)N 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25617109P | 2009-10-29 | 2009-10-29 | |
| US61/256,171 | 2009-10-29 | ||
| PCT/US2010/054445 WO2011059731A1 (en) | 2009-10-29 | 2010-10-28 | Alkynyl derivatives useful as dpp-1 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013509423A JP2013509423A (ja) | 2013-03-14 |
| JP2013509423A5 true JP2013509423A5 (enExample) | 2013-12-19 |
| JP5815542B2 JP5815542B2 (ja) | 2015-11-17 |
Family
ID=43503067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012537052A Expired - Fee Related JP5815542B2 (ja) | 2009-10-29 | 2010-10-28 | Ｄｐｐ−１阻害剤として有用なアルキニル誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8633322B2 (enExample) |
| EP (1) | EP2493571B1 (enExample) |
| JP (1) | JP5815542B2 (enExample) |
| CN (1) | CN102596321B (enExample) |
| AU (1) | AU2010319927B2 (enExample) |
| ES (1) | ES2513291T3 (enExample) |
| WO (1) | WO2011059731A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012119941A1 (en) | 2011-03-04 | 2012-09-13 | Prozymex A/S | Peptidyl nitrilcompounds as peptidase inhibitors |
| EP2825533B1 (en) | 2012-03-13 | 2016-10-19 | Basf Se | Fungicidal pyrimidine compounds |
| AR091858A1 (es) | 2012-07-25 | 2015-03-04 | Sova Pharmaceuticals Inc | INHIBIDORES DE CISTATIONIN-g-LIASA (CSE) |
| CA2923101A1 (en) | 2013-09-16 | 2015-03-19 | Basf Se | Fungicidal pyrimidine compounds |
| WO2015036059A1 (en) | 2013-09-16 | 2015-03-19 | Basf Se | Fungicidal pyrimidine compounds |
| EP4497473A3 (en) | 2020-08-26 | 2025-04-23 | Haisco Pharmaceuticals Pte. Ltd. | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US548021A (en) * | 1895-10-15 | Wiiitfield potter toomee | ||
| US4847241A (en) * | 1985-08-14 | 1989-07-11 | G. D. Searle & Co. | Fluorenyl substituted tyrosyl dipeptide amides which are useful in treating pain |
| CA2099994C (en) | 1991-03-06 | 2003-05-20 | Robert B. Garland | Phenyl amidines derivatives useful as platelet aggregation inhibitors |
| US5424334A (en) | 1991-12-19 | 1995-06-13 | G. D. Searle & Co. | Peptide mimetic compounds useful as platelet aggregation inhibitors |
| DE4321502A1 (de) | 1993-06-29 | 1995-01-12 | Bayer Ag | Alkinol-substituierte Peptide, Verfahren zu ihrer Herstellung und ihre Verwendung als antiretrovirale Mittel |
| AU6490396A (en) | 1995-07-14 | 1997-02-18 | Smithkline Beecham Corporation | Substituted-pent-4-ynoic acids |
| NZ318926A (en) | 1995-08-30 | 1999-04-29 | Searle & Co | Alpha v beta 3 integrin (vitronectin) inhibitors or anatagonists derived from benzoic acid for treating diseases of cell adhesion |
| JP2002145897A (ja) | 2000-11-10 | 2002-05-22 | Kyorin Pharmaceut Co Ltd | アミノ酸誘導体及びその製造法 |
| CA2480378A1 (en) * | 2002-05-07 | 2003-11-20 | Neurosearch A/S | Novel azacyclic ethynyl derivatives |
| DE60226906D1 (de) * | 2002-07-31 | 2008-07-10 | Ranbaxy Lab Ltd | 3,6-disubstituierte azabicyclo ä3.1.0ühexanderivate, die sich als muscarinrezeptorantagonisten eignen |
| US20040186151A1 (en) * | 2003-02-12 | 2004-09-23 | Mjalli Adnan M.M. | Substituted azole derivatives as therapeutic agents |
| AU2004210711B2 (en) * | 2003-02-12 | 2010-07-08 | Transtech Pharma, Inc. | Substituted azole derivatives as therapeutic agents |
| US20070155803A1 (en) * | 2003-05-30 | 2007-07-05 | Prozymex A/S | Protease inhibitors |
| US7638513B2 (en) * | 2004-06-02 | 2009-12-29 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
| DE102005009784B4 (de) * | 2005-03-03 | 2009-06-18 | Technische Universität Darmstadt | Peptid-Mimetika, Verfahren zur deren Herstellung, diese enthaltende pharmazeutische Zusammensetzung und deren Verwendung als Inhibitoren von Proteasomen und zur Induktion von Apoptose |
| KR20080004550A (ko) * | 2005-03-30 | 2008-01-09 | 콘포마 세러퓨틱스 코포레이션 | Ｈｓｐ９０-억제제로서 알키닐 피롤로피리미딘 및 관련유사체 |
| BRPI0708942A2 (pt) | 2006-03-21 | 2011-06-14 | Joyant Pharmaceuticals Inc | composto promotor de apoptose, uso e mÉtodo de produÇço do mesmo e composiÇço farmacÊutica |
| US7678894B2 (en) | 2007-05-18 | 2010-03-16 | Helicos Biosciences Corporation | Nucleotide analogs |
| TW200922556A (en) | 2007-08-20 | 2009-06-01 | Glaxo Group Ltd | Novel cathepsin C inhibitors and their use |
| BRPI0820665A2 (pt) | 2007-12-12 | 2018-05-29 | Astrazeneca Ab | compostos de peptidil nitrilas, processos para fabricação dos mesmos, composição farmacêutica, combinação e uso de ditos compostos |
-
2010
- 2010-10-28 US US12/914,244 patent/US8633322B2/en active Active
- 2010-10-28 CN CN201080049814.4A patent/CN102596321B/zh not_active Expired - Fee Related
- 2010-10-28 WO PCT/US2010/054445 patent/WO2011059731A1/en not_active Ceased
- 2010-10-28 EP EP10774098.7A patent/EP2493571B1/en active Active
- 2010-10-28 ES ES10774098.7T patent/ES2513291T3/es active Active
- 2010-10-28 AU AU2010319927A patent/AU2010319927B2/en not_active Ceased
- 2010-10-28 JP JP2012537052A patent/JP5815542B2/ja not_active Expired - Fee Related
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