JP2013507408A5 - - Google Patents
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- Publication number
- JP2013507408A5 JP2013507408A5 JP2012533530A JP2012533530A JP2013507408A5 JP 2013507408 A5 JP2013507408 A5 JP 2013507408A5 JP 2012533530 A JP2012533530 A JP 2012533530A JP 2012533530 A JP2012533530 A JP 2012533530A JP 2013507408 A5 JP2013507408 A5 JP 2013507408A5
- Authority
- JP
- Japan
- Prior art keywords
- celecoxib
- pharmaceutical composition
- rac
- tramadol
- hcl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- RZEKVGVHFLEQIL-UHFFFAOYSA-N celecoxib Chemical compound C1=CC(C)=CC=C1C1=CC(C(F)(F)F)=NN1C1=CC=C(S(N)(=O)=O)C=C1 RZEKVGVHFLEQIL-UHFFFAOYSA-N 0.000 claims 4
- 229960000590 celecoxib Drugs 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 229960004380 tramadol Drugs 0.000 claims 2
- 230000007935 neutral effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011885 synergistic combination Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09384004A EP2311446A1 (en) | 2009-10-16 | 2009-10-16 | Compositions comprising Tramadol and Celecoxib in the treatment of pain |
| EP09384004.9 | 2009-10-16 | ||
| PCT/EP2010/006317 WO2011045075A1 (en) | 2009-10-16 | 2010-10-15 | Compositions comprising tramadol and celecoxib in the treatment of pain |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014141720A Division JP2014221797A (ja) | 2009-10-16 | 2014-07-09 | トラマドール及びセレコキシブを含む疼痛治療用組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013507408A JP2013507408A (ja) | 2013-03-04 |
| JP2013507408A5 true JP2013507408A5 (enExample) | 2013-11-28 |
| JP5579858B2 JP5579858B2 (ja) | 2014-08-27 |
Family
ID=41566149
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012533530A Active JP5579858B2 (ja) | 2009-10-16 | 2010-10-15 | トラマドール及びセレコキシブを含む疼痛治療用組成物 |
| JP2014141720A Withdrawn JP2014221797A (ja) | 2009-10-16 | 2014-07-09 | トラマドール及びセレコキシブを含む疼痛治療用組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014141720A Withdrawn JP2014221797A (ja) | 2009-10-16 | 2014-07-09 | トラマドール及びセレコキシブを含む疼痛治療用組成物 |
Country Status (33)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2177215A1 (en) | 2008-10-17 | 2010-04-21 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of tramadol and NSAIDs |
| US8746719B2 (en) * | 2010-08-03 | 2014-06-10 | Polaris Industries Inc. | Side-by-side vehicle |
| EP2694048B1 (en) * | 2011-04-05 | 2020-10-07 | Optosolve Research & Development Ltd | Ophthalmic treatments |
| PT2811833E (pt) * | 2012-02-06 | 2015-12-07 | William L Pridgen | Associação de famciclovir e celecoxib para síndromes somáticas funcionais |
| WO2016116942A1 (en) | 2015-01-20 | 2016-07-28 | Anlon Chemical Research Organization | Novel pharmaceutical compounds comprising ticagrelor with salts of aspirin |
| JP6605047B2 (ja) * | 2015-05-28 | 2019-11-13 | ドクター・レディーズ・ラボラトリーズ・リミテッド | 疼痛治療のためのセレコキシブの経口用組成物 |
| KR101710792B1 (ko) * | 2015-07-14 | 2017-02-28 | 주식회사 유영제약 | 세레콕시브 및 트라마돌을 함유하는 약제학적 조성물 |
| MX2016006464A (es) * | 2016-05-18 | 2017-11-17 | Laboratorios Liomont S A De C V | Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor. |
| BR112018074486A2 (pt) * | 2016-05-27 | 2019-05-28 | Dr Reddy´S Laboratories Ltd | composição oral de celecoxib para tratamento da dor |
| WO2018186650A2 (ko) * | 2017-04-03 | 2018-10-11 | 주식회사 킴스헬스케어 | 트라마돌과 셀레콕시브를 포함한 경구투여용 이중 복합정제 |
| US20200323780A1 (en) * | 2017-04-03 | 2020-10-15 | Kims Healthcare Co., Ltd. | Bilayer combination tablet for oral administration containing tramadol and celecoxib |
| KR102631399B1 (ko) | 2018-03-30 | 2024-02-01 | 씨지인바이츠 주식회사 | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
| CA3137381A1 (en) * | 2019-05-14 | 2020-11-19 | Esteve Pharmaceuticals, S.A. | Use of co-crystals of tramadol and celecoxib for treating pain while reducing the abuse liability of tramadol |
| CN112007024A (zh) * | 2019-05-28 | 2020-12-01 | 江苏恒瑞医药股份有限公司 | 艾瑞昔布与曲马多联合在制备治疗疼痛的药物中的用途 |
| CN114681470A (zh) | 2020-12-28 | 2022-07-01 | 雷迪博士实验室有限公司 | 治疗疼痛的方法 |
| WO2025125888A1 (en) * | 2023-12-15 | 2025-06-19 | Centro De Investigación Y De Estudios Avanzados Del I.P.N. | Aripiprazole and tramadol compositions with potentiation effects and high analgesic efficacy useful for the treatment of neuropathic pain |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5516803A (en) | 1991-10-30 | 1996-05-14 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| AU661723B2 (en) | 1991-10-30 | 1995-08-03 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| RS49982B (sr) * | 1997-09-17 | 2008-09-29 | Euro-Celtique S.A., | Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2 |
| NZ513924A (en) | 1999-03-01 | 2001-09-28 | Ortho Mcneil Pharm Inc | Composition comprising a tramadol material and a selective cox-2 inhibitor drug |
| DE19927688A1 (de) | 1999-06-17 | 2000-12-21 | Gruenenthal Gmbh | Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
| US7790905B2 (en) * | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
| PT1478366E (pt) * | 2002-02-19 | 2009-03-10 | Adcock Ingram Ltd | Combinações farmacêuticas de meloxicam, fosfato de codeína e paracetamol |
| US20080031950A1 (en) * | 2007-04-27 | 2008-02-07 | Nectid Inc. | Novel anelgesic combination |
| JP5399564B2 (ja) | 2009-10-16 | 2014-01-29 | ラボラトリオス・デル・デエレ・エステベ・エセ・ア | トラマドールとコキシブとの共結晶 |
| EP2392319A1 (en) | 2010-06-04 | 2011-12-07 | Laboratorios Del. Dr. Esteve, S.A. | Pharmaceutical compositions of co-crystals of tramadol and coxibs |
-
2009
- 2009-10-16 EP EP09384004A patent/EP2311446A1/en not_active Withdrawn
-
2010
- 2010-10-14 TW TW99134996A patent/TWI466668B/zh active
- 2010-10-15 AU AU2010306114A patent/AU2010306114B2/en active Active
- 2010-10-15 HR HRP20140157AT patent/HRP20140157T1/hr unknown
- 2010-10-15 US US13/394,995 patent/US8569271B2/en active Active
- 2010-10-15 SI SI201030545T patent/SI2488170T1/sl unknown
- 2010-10-15 JP JP2012533530A patent/JP5579858B2/ja active Active
- 2010-10-15 PT PT107657629T patent/PT2488170E/pt unknown
- 2010-10-15 EP EP13005822.5A patent/EP2737898A1/en not_active Withdrawn
- 2010-10-15 EP EP10765762.9A patent/EP2488170B1/en active Active
- 2010-10-15 KR KR1020127009600A patent/KR101688996B1/ko not_active Ceased
- 2010-10-15 CN CN201611195215.9A patent/CN107050006A/zh active Pending
- 2010-10-15 RS RS20140100A patent/RS53202B/sr unknown
- 2010-10-15 RU RU2012120087/15A patent/RU2012120087A/ru unknown
- 2010-10-15 CA CA2771651A patent/CA2771651C/en active Active
- 2010-10-15 MX MX2012003051A patent/MX2012003051A/es active IP Right Grant
- 2010-10-15 AR ARP100103776A patent/AR078653A1/es not_active Application Discontinuation
- 2010-10-15 ES ES10765762.9T patent/ES2450615T3/es active Active
- 2010-10-15 BR BR112012005044A patent/BR112012005044B8/pt active IP Right Grant
- 2010-10-15 DK DK10765762.9T patent/DK2488170T3/en active
- 2010-10-15 MY MYPI2012000614A patent/MY156275A/en unknown
- 2010-10-15 CN CN2010800463605A patent/CN102573824A/zh active Pending
- 2010-10-15 WO PCT/EP2010/006317 patent/WO2011045075A1/en not_active Ceased
- 2010-10-15 PL PL10765762T patent/PL2488170T3/pl unknown
- 2010-10-15 SG SG2012010898A patent/SG178833A1/en unknown
- 2010-10-15 UA UAA201205897A patent/UA108213C2/uk unknown
- 2010-10-15 NZ NZ598361A patent/NZ598361A/en unknown
- 2010-10-15 IN IN1434DEN2012 patent/IN2012DN01434A/en unknown
- 2010-10-15 RU RU2016125895A patent/RU2707752C2/ru active
-
2012
- 2012-02-10 TN TNP2012000059A patent/TN2012000059A1/en unknown
- 2012-02-14 IL IL218096A patent/IL218096A/en active IP Right Grant
- 2012-03-16 CO CO12046133A patent/CO6511249A2/es active IP Right Grant
- 2012-03-19 EC ECSP12011735 patent/ECSP12011735A/es unknown
- 2012-03-23 ZA ZA2012/02151A patent/ZA201202151B/en unknown
- 2012-05-11 MA MA34860A patent/MA33743B1/fr unknown
-
2013
- 2013-09-25 US US14/036,828 patent/US20140024622A1/en not_active Abandoned
-
2014
- 2014-03-10 CY CY20141100195T patent/CY1114960T1/el unknown
- 2014-03-20 SM SM201400035T patent/SMT201400035B/xx unknown
- 2014-07-09 JP JP2014141720A patent/JP2014221797A/ja not_active Withdrawn
-
2015
- 2015-02-04 US US14/613,475 patent/US20150150889A1/en not_active Abandoned
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