CN107050006A - 治疗疼痛的包含曲马多和塞来昔布的组合物 - Google Patents

治疗疼痛的包含曲马多和塞来昔布的组合物 Download PDF

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Publication number
CN107050006A
CN107050006A CN201611195215.9A CN201611195215A CN107050006A CN 107050006 A CN107050006 A CN 107050006A CN 201611195215 A CN201611195215 A CN 201611195215A CN 107050006 A CN107050006 A CN 107050006A
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CN
China
Prior art keywords
pain
pharmaceutical composition
celecoxib
tramadol
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611195215.9A
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English (en)
Chinese (zh)
Inventor
恩里克·波蒂略萨利多
塞巴斯蒂亚·维德拉塞斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41566149&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN107050006(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of CN107050006A publication Critical patent/CN107050006A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201611195215.9A 2009-10-16 2010-10-15 治疗疼痛的包含曲马多和塞来昔布的组合物 Pending CN107050006A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09384004A EP2311446A1 (en) 2009-10-16 2009-10-16 Compositions comprising Tramadol and Celecoxib in the treatment of pain
EP09384004.9 2009-10-16
CN2010800463605A CN102573824A (zh) 2009-10-16 2010-10-15 治疗疼痛的包含曲马多和塞来昔布的组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2010800463605A Division CN102573824A (zh) 2009-10-16 2010-10-15 治疗疼痛的包含曲马多和塞来昔布的组合物

Publications (1)

Publication Number Publication Date
CN107050006A true CN107050006A (zh) 2017-08-18

Family

ID=41566149

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201611195215.9A Pending CN107050006A (zh) 2009-10-16 2010-10-15 治疗疼痛的包含曲马多和塞来昔布的组合物
CN2010800463605A Pending CN102573824A (zh) 2009-10-16 2010-10-15 治疗疼痛的包含曲马多和塞来昔布的组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2010800463605A Pending CN102573824A (zh) 2009-10-16 2010-10-15 治疗疼痛的包含曲马多和塞来昔布的组合物

Country Status (33)

Country Link
US (3) US8569271B2 (enExample)
EP (3) EP2311446A1 (enExample)
JP (2) JP5579858B2 (enExample)
KR (1) KR101688996B1 (enExample)
CN (2) CN107050006A (enExample)
AR (1) AR078653A1 (enExample)
AU (1) AU2010306114B2 (enExample)
BR (1) BR112012005044B8 (enExample)
CA (1) CA2771651C (enExample)
CO (1) CO6511249A2 (enExample)
CY (1) CY1114960T1 (enExample)
DK (1) DK2488170T3 (enExample)
EC (1) ECSP12011735A (enExample)
ES (1) ES2450615T3 (enExample)
HR (1) HRP20140157T1 (enExample)
IL (1) IL218096A (enExample)
IN (1) IN2012DN01434A (enExample)
MA (1) MA33743B1 (enExample)
MX (1) MX2012003051A (enExample)
MY (1) MY156275A (enExample)
NZ (1) NZ598361A (enExample)
PL (1) PL2488170T3 (enExample)
PT (1) PT2488170E (enExample)
RS (1) RS53202B (enExample)
RU (2) RU2707752C2 (enExample)
SG (1) SG178833A1 (enExample)
SI (1) SI2488170T1 (enExample)
SM (1) SMT201400035B (enExample)
TN (1) TN2012000059A1 (enExample)
TW (1) TWI466668B (enExample)
UA (1) UA108213C2 (enExample)
WO (1) WO2011045075A1 (enExample)
ZA (1) ZA201202151B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112007024A (zh) * 2019-05-28 2020-12-01 江苏恒瑞医药股份有限公司 艾瑞昔布与曲马多联合在制备治疗疼痛的药物中的用途

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2177215A1 (en) 2008-10-17 2010-04-21 Laboratorios Del. Dr. Esteve, S.A. Co-crystals of tramadol and NSAIDs
US8746719B2 (en) 2010-08-03 2014-06-10 Polaris Industries Inc. Side-by-side vehicle
MX346312B (es) * 2011-04-05 2017-03-15 Optosolve Res & Dev Ltd Tratamientos oftalmicos.
ES2551427T3 (es) 2012-02-06 2015-11-19 William L. Pridgen Combinación de famciclovir y celecoxib para síndromes somáticos funcionales
WO2016116942A1 (en) 2015-01-20 2016-07-28 Anlon Chemical Research Organization Novel pharmaceutical compounds comprising ticagrelor with salts of aspirin
WO2016191744A1 (en) * 2015-05-28 2016-12-01 Dr. Reddy's Laboratories Ltd. Oral composition of celecoxib for treatment of pain
KR101710792B1 (ko) * 2015-07-14 2017-02-28 주식회사 유영제약 세레콕시브 및 트라마돌을 함유하는 약제학적 조성물
MX2016006464A (es) * 2016-05-18 2017-11-17 Laboratorios Liomont S A De C V Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor.
US10722456B2 (en) * 2016-05-27 2020-07-28 Dr. Reddy's Laboratories Ltd Oral composition of celecoxib for treatment of pain
WO2018186650A2 (ko) * 2017-04-03 2018-10-11 주식회사 킴스헬스케어 트라마돌과 셀레콕시브를 포함한 경구투여용 이중 복합정제
KR102033716B1 (ko) 2017-04-03 2019-10-17 주식회사 킴스헬스케어 트라마돌과 셀레콕시브를 포함한 경구투여용 이중 복합정제
KR102631399B1 (ko) 2018-03-30 2024-02-01 씨지인바이츠 주식회사 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물
BR112021020893A2 (pt) * 2019-05-14 2022-04-19 Esteve Pharmaceuticals Sa Uso de cocristais de tramadol e celecoxib para o tratamento de dor, ao mesmo tempo que reduzindo a suscetibilidade a abuso do tramadol
EP4267132A1 (en) 2020-12-28 2023-11-01 Dr. Reddy's Laboratories Ltd. Celecoxib for treating pain
WO2025125888A1 (en) * 2023-12-15 2025-06-19 Centro De Investigación Y De Estudios Avanzados Del I.P.N. Aripiprazole and tramadol compositions with potentiation effects and high analgesic efficacy useful for the treatment of neuropathic pain

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CN1349423A (zh) * 1999-03-01 2002-05-15 奥索-麦克尼尔药品公司 包含曲马多物质和选择性cox－2抑制剂药物的组合物
US20050090517A1 (en) * 2002-02-19 2005-04-28 Norris Michael C. Pharmaceutical combinations of cox-2 inhibitors and opiates

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US5516803A (en) 1991-10-30 1996-05-14 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
AU661723B2 (en) 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
RS49982B (sr) * 1997-09-17 2008-09-29 Euro-Celtique S.A., Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
DE19927688A1 (de) 1999-06-17 2000-12-21 Gruenenthal Gmbh Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US20080031950A1 (en) * 2007-04-27 2008-02-07 Nectid Inc. Novel anelgesic combination
HRP20130316T1 (en) 2009-10-16 2013-05-31 Laboratorios Del Dr. Esteve, S.A. Co-crystals of tramadol and coxibs
EP2392319A1 (en) 2010-06-04 2011-12-07 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical compositions of co-crystals of tramadol and coxibs

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1349423A (zh) * 1999-03-01 2002-05-15 奥索-麦克尼尔药品公司 包含曲马多物质和选择性cox－2抑制剂药物的组合物
US20050090517A1 (en) * 2002-02-19 2005-04-28 Norris Michael C. Pharmaceutical combinations of cox-2 inhibitors and opiates

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112007024A (zh) * 2019-05-28 2020-12-01 江苏恒瑞医药股份有限公司 艾瑞昔布与曲马多联合在制备治疗疼痛的药物中的用途

Also Published As

Publication number Publication date
CO6511249A2 (es) 2012-08-31
KR20120089287A (ko) 2012-08-09
MA33743B1 (fr) 2012-11-01
RU2707752C2 (ru) 2019-11-29
RU2016125895A3 (enExample) 2018-12-05
ZA201202151B (en) 2012-11-28
BR112012005044B8 (pt) 2021-05-25
US20150150889A1 (en) 2015-06-04
DK2488170T3 (en) 2014-03-03
HK1173379A1 (en) 2013-05-16
IN2012DN01434A (enExample) 2015-06-05
BR112012005044A2 (pt) 2016-05-03
CY1114960T1 (el) 2016-12-14
PT2488170E (pt) 2014-03-11
UA108213C2 (uk) 2015-04-10
AU2010306114A1 (en) 2012-03-15
US20120172341A1 (en) 2012-07-05
KR101688996B1 (ko) 2016-12-22
IL218096A0 (en) 2012-04-30
PL2488170T3 (pl) 2014-05-30
SI2488170T1 (sl) 2014-04-30
TWI466668B (zh) 2015-01-01
RS53202B (sr) 2014-06-30
NZ598361A (en) 2014-01-31
SG178833A1 (en) 2012-05-30
US20140024622A1 (en) 2014-01-23
RU2012120087A (ru) 2013-11-27
IL218096A (en) 2015-02-26
US8569271B2 (en) 2013-10-29
ECSP12011735A (es) 2012-05-30
EP2488170B1 (en) 2014-01-22
BR112012005044B1 (pt) 2020-12-15
SMT201400035B (it) 2014-05-07
ES2450615T3 (es) 2014-03-25
JP2013507408A (ja) 2013-03-04
EP2311446A1 (en) 2011-04-20
JP2014221797A (ja) 2014-11-27
WO2011045075A1 (en) 2011-04-21
EP2488170A1 (en) 2012-08-22
TW201114418A (en) 2011-05-01
TN2012000059A1 (en) 2013-09-19
MX2012003051A (es) 2012-05-29
CN102573824A (zh) 2012-07-11
CA2771651A1 (en) 2011-04-11
AR078653A1 (es) 2011-11-23
CA2771651C (en) 2016-08-23
MY156275A (en) 2016-01-29
EP2737898A1 (en) 2014-06-04
AU2010306114B2 (en) 2015-07-23
RU2016125895A (ru) 2018-12-05
JP5579858B2 (ja) 2014-08-27
HRP20140157T1 (hr) 2014-03-28

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SE01 Entry into force of request for substantive examination
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Address after: Spain Barcelona

Applicant after: Esteven Pharmaceutical Co.,Ltd.

Address before: Spain Barcelona

Applicant before: LABORATORIOS DEL DR. ESTEVE, S.A.

RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20170818