JP2013505255A5 - - Google Patents
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- Publication number
- JP2013505255A5 JP2013505255A5 JP2012529909A JP2012529909A JP2013505255A5 JP 2013505255 A5 JP2013505255 A5 JP 2013505255A5 JP 2012529909 A JP2012529909 A JP 2012529909A JP 2012529909 A JP2012529909 A JP 2012529909A JP 2013505255 A5 JP2013505255 A5 JP 2013505255A5
- Authority
- JP
- Japan
- Prior art keywords
- digestive enzyme
- multiparticulate
- coating
- enzyme composition
- lipase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000038379 digestive enzymes Human genes 0.000 claims 42
- 108091007734 digestive enzymes Proteins 0.000 claims 42
- 239000011324 bead Substances 0.000 claims 24
- 239000000203 mixture Substances 0.000 claims 24
- 108091005804 Peptidases Proteins 0.000 claims 15
- 239000004365 Protease Substances 0.000 claims 15
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 15
- 239000011248 coating agent Substances 0.000 claims 13
- 238000000576 coating method Methods 0.000 claims 13
- 239000002702 enteric coating Substances 0.000 claims 10
- 238000009505 enteric coating Methods 0.000 claims 10
- 230000000694 effects Effects 0.000 claims 9
- 235000019626 lipase activity Nutrition 0.000 claims 9
- 102000004882 Lipase Human genes 0.000 claims 7
- 108090001060 Lipase Proteins 0.000 claims 7
- 239000004367 Lipase Substances 0.000 claims 6
- 235000019421 lipase Nutrition 0.000 claims 6
- 239000002552 dosage form Substances 0.000 claims 4
- 208000035467 Pancreatic insufficiency Diseases 0.000 claims 2
- 206010033645 Pancreatitis Diseases 0.000 claims 2
- 235000012054 meals Nutrition 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 206010000087 Abdominal pain upper Diseases 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24346709P | 2009-09-17 | 2009-09-17 | |
| US61/243,467 | 2009-09-17 | ||
| PCT/US2010/049203 WO2011035079A1 (en) | 2009-09-17 | 2010-09-17 | Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013505255A JP2013505255A (ja) | 2013-02-14 |
| JP2013505255A5 true JP2013505255A5 (https=) | 2013-11-07 |
| JP5877399B2 JP5877399B2 (ja) | 2016-03-08 |
Family
ID=43730817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012529909A Expired - Fee Related JP5877399B2 (ja) | 2009-09-17 | 2010-09-17 | 膵炎及び膵不全を治療するための膵酵素組成物及び方法 |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8784884B2 (https=) |
| EP (1) | EP2477645B1 (https=) |
| JP (1) | JP5877399B2 (https=) |
| KR (1) | KR101771752B1 (https=) |
| CN (2) | CN102630164B (https=) |
| AR (1) | AR078291A1 (https=) |
| AU (1) | AU2010295494B2 (https=) |
| BR (1) | BR112012005837A8 (https=) |
| CA (1) | CA2774269C (https=) |
| CL (1) | CL2012000658A1 (https=) |
| CO (1) | CO6531419A2 (https=) |
| ES (1) | ES2690661T3 (https=) |
| HK (1) | HK1218886A1 (https=) |
| IL (2) | IL218656A (https=) |
| MX (1) | MX2012003214A (https=) |
| MY (1) | MY161843A (https=) |
| NZ (1) | NZ599143A (https=) |
| RU (1) | RU2570376C2 (https=) |
| SA (1) | SA110310695B1 (https=) |
| TW (2) | TW201639545A (https=) |
| UY (1) | UY32896A (https=) |
| WO (1) | WO2011035079A1 (https=) |
| ZA (1) | ZA201202761B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
| US8246950B2 (en) | 2007-02-20 | 2012-08-21 | Aptalis Pharma Limited | Stable digestive enzyme compositions |
| WO2009109856A2 (en) | 2008-03-07 | 2009-09-11 | Axcan Pharma Inc. | Method for detecting infectious parvovirus in pharmaceutical preparations |
| UA111726C2 (uk) * | 2010-10-01 | 2016-06-10 | Апталіс Фарма Лімітед | Препарат панкреліпази низької сили з кишковорозчинним покриттям |
| CA2843556A1 (en) * | 2011-08-08 | 2013-02-14 | Aptalis Pharma Ltd. | Method for dissolution testing of solid compositions containing digestive enzymes |
| MX2016001593A (es) | 2013-08-09 | 2016-09-29 | Allergan Pharmaceuticals Int Ltd | Composicion de enzima digestiva adecuada para administracion enterica. |
| JP2017519490A (ja) | 2014-06-19 | 2017-07-20 | アプタリス ファルマ リミテッド | 膵臓抽出物からのウイルス汚染の除去方法 |
| FR3079146B1 (fr) * | 2018-03-23 | 2020-04-17 | Karim Ioualalen | Formulation gastroprotectrice de complexes d’enzymes permettant de restaurer la fonction digestive. |
| WO2021202363A1 (en) * | 2020-03-30 | 2021-10-07 | Wall Jai | Combined animal-derived and synthetically produced pancreatic enzyme replacement therapy |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1509866A (en) | 1975-06-10 | 1978-05-04 | Johnson & Johnson | Enteric coated digestive enzyme compositions |
| US4447412A (en) * | 1983-02-01 | 1984-05-08 | Bilton Gerald L | Enzyme-containing digestive aid compostions |
| US5460812A (en) | 1992-06-22 | 1995-10-24 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| US5260074A (en) | 1992-06-22 | 1993-11-09 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| US5578304A (en) | 1992-06-22 | 1996-11-26 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| US5302400A (en) | 1992-06-22 | 1994-04-12 | Digestive Care Inc. | Preparation of gastric acid-resistant microspheres containing digestive enzymes and buffered-bile acids |
| DE4227385A1 (de) | 1992-08-19 | 1994-02-24 | Kali Chemie Pharma Gmbh | Pankreatinmikropellets |
| EP0879048B2 (en) | 1996-02-09 | 2009-07-29 | Quadrant Drug Delivery Limited | Method for making tablets using trehalose |
| US5750104A (en) | 1996-05-29 | 1998-05-12 | Digestive Care Inc. | High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith |
| US20010046493A1 (en) | 2000-02-24 | 2001-11-29 | Alex Margolin | Lipase-containing composition and methods of use thereof |
| CN1156308C (zh) * | 2002-04-19 | 2004-07-07 | 北京世诺医药科技有限公司 | 多酶组合胶囊 |
| US20040121010A1 (en) * | 2002-10-25 | 2004-06-24 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| EP1596838A2 (en) | 2003-02-11 | 2005-11-23 | Torrent Pharmaceuticals Ltd | Once a day orally administered pharmaceutical compositions comprising a proton pump inhibitor and a prokinetic agent |
| KR20060127857A (ko) * | 2003-10-29 | 2006-12-13 | 알투스 파마슈티컬스 인코포레이티드 | 혈장 콜레시스토키닌(ｃｃｋ) 농도 조절 및 통증 치료를위한 비-췌장 프로테아제 |
| US7387793B2 (en) | 2003-11-14 | 2008-06-17 | Eurand, Inc. | Modified release dosage forms of skeletal muscle relaxants |
| US7470435B2 (en) | 2003-11-17 | 2008-12-30 | Andrx Pharmaceuticals, Llc | Extended release venlafaxine formulation |
| CA2560613C (en) | 2004-03-22 | 2015-11-24 | Solvay Pharmaceuticals Gmbh | Oral pharmaceutical compositions of lipase-containing products, in particular of pancreatin, containing surfactants |
| DK1755656T3 (da) * | 2004-05-24 | 2010-10-04 | Novozymes As | Enzymer til farmaceutisk anvendelse |
| PT1809320E (pt) * | 2004-10-14 | 2010-10-25 | Altus Pharmaceuticals Inc | Composições contendo lipase, protease e amilase para o tratamento de insuficiência pancreática |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| CN101208429A (zh) * | 2005-06-24 | 2008-06-25 | 诺维信公司 | 用于药物用途的脂肪酶 |
| US20070025977A1 (en) | 2005-07-21 | 2007-02-01 | Mulberg Andrew E | Method of treating steatorrhea in infants |
| HUE031042T2 (en) | 2005-07-29 | 2017-06-28 | Abbott Laboratories Gmbh | Methods for producing pancreatin powder with low viral content |
| US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
| US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
| WO2007053619A2 (en) * | 2005-11-01 | 2007-05-10 | Bio-Cat, Inc. | A composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrous as well as people suffering from pancreatic lipase insufficiency |
| MX2008015031A (es) * | 2006-05-26 | 2008-12-05 | Nestec Sa | Metodos de uso y composiciones nutritivas de extracto de touchi. |
| US20080199448A1 (en) * | 2007-02-16 | 2008-08-21 | Ross Mairi R | Enzyme composition for improving food digestion |
| US8246950B2 (en) | 2007-02-20 | 2012-08-21 | Aptalis Pharma Limited | Stable digestive enzyme compositions |
| US20090117180A1 (en) * | 2007-02-20 | 2009-05-07 | Giovanni Ortenzi | Stable digestive enzyme compositions |
| EP2328566A1 (en) | 2008-09-30 | 2011-06-08 | DSM IP Assets B.V. | Enzyme composition and application thereof in the treatment of pancreatic insufficiency |
-
2009
- 2009-09-28 US US12/568,064 patent/US8784884B2/en active Active
-
2010
- 2010-09-16 TW TW105126319A patent/TW201639545A/zh unknown
- 2010-09-16 TW TW099131496A patent/TWI572372B/zh not_active IP Right Cessation
- 2010-09-17 AR ARP100103408A patent/AR078291A1/es not_active Application Discontinuation
- 2010-09-17 NZ NZ599143A patent/NZ599143A/en not_active IP Right Cessation
- 2010-09-17 MY MYPI2012001215A patent/MY161843A/en unknown
- 2010-09-17 AU AU2010295494A patent/AU2010295494B2/en not_active Ceased
- 2010-09-17 KR KR1020127009516A patent/KR101771752B1/ko not_active Expired - Fee Related
- 2010-09-17 CA CA2774269A patent/CA2774269C/en not_active Expired - Fee Related
- 2010-09-17 RU RU2012113253/15A patent/RU2570376C2/ru active
- 2010-09-17 BR BR112012005837A patent/BR112012005837A8/pt not_active Application Discontinuation
- 2010-09-17 MX MX2012003214A patent/MX2012003214A/es active IP Right Grant
- 2010-09-17 EP EP10817867.4A patent/EP2477645B1/en not_active Revoked
- 2010-09-17 UY UY0001032896A patent/UY32896A/es not_active Application Discontinuation
- 2010-09-17 JP JP2012529909A patent/JP5877399B2/ja not_active Expired - Fee Related
- 2010-09-17 WO PCT/US2010/049203 patent/WO2011035079A1/en not_active Ceased
- 2010-09-17 ES ES10817867.4T patent/ES2690661T3/es active Active
- 2010-09-17 CN CN201080041366.3A patent/CN102630164B/zh not_active Expired - Fee Related
- 2010-09-17 CN CN201510490337.XA patent/CN105214073A/zh active Pending
- 2010-09-18 SA SA110310695A patent/SA110310695B1/ar unknown
-
2012
- 2012-03-15 CL CL2012000658A patent/CL2012000658A1/es unknown
- 2012-03-15 IL IL218656A patent/IL218656A/en active IP Right Grant
- 2012-03-26 CO CO12050658A patent/CO6531419A2/es unknown
- 2012-04-16 ZA ZA2012/02761A patent/ZA201202761B/en unknown
-
2014
- 2014-06-05 US US14/296,832 patent/US20160051472A9/en not_active Abandoned
-
2016
- 2016-05-26 IL IL245875A patent/IL245875A0/en unknown
- 2016-06-17 HK HK16107000.5A patent/HK1218886A1/zh unknown
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