CA2774269C - Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency - Google Patents
Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency Download PDFInfo
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- CA2774269C CA2774269C CA2774269A CA2774269A CA2774269C CA 2774269 C CA2774269 C CA 2774269C CA 2774269 A CA2774269 A CA 2774269A CA 2774269 A CA2774269 A CA 2774269A CA 2774269 C CA2774269 C CA 2774269C
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- digestive enzyme
- lipase
- units
- protease
- usp
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24346709P | 2009-09-17 | 2009-09-17 | |
| US61/243,467 | 2009-09-17 | ||
| PCT/US2010/049203 WO2011035079A1 (en) | 2009-09-17 | 2010-09-17 | Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2774269A1 CA2774269A1 (en) | 2011-03-24 |
| CA2774269C true CA2774269C (en) | 2017-03-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2774269A Expired - Fee Related CA2774269C (en) | 2009-09-17 | 2010-09-17 | Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency |
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| EP (1) | EP2477645B1 (https=) |
| JP (1) | JP5877399B2 (https=) |
| KR (1) | KR101771752B1 (https=) |
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| AR (1) | AR078291A1 (https=) |
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| BR (1) | BR112012005837A8 (https=) |
| CA (1) | CA2774269C (https=) |
| CL (1) | CL2012000658A1 (https=) |
| CO (1) | CO6531419A2 (https=) |
| ES (1) | ES2690661T3 (https=) |
| HK (1) | HK1218886A1 (https=) |
| IL (2) | IL218656A (https=) |
| MX (1) | MX2012003214A (https=) |
| MY (1) | MY161843A (https=) |
| NZ (1) | NZ599143A (https=) |
| RU (1) | RU2570376C2 (https=) |
| SA (1) | SA110310695B1 (https=) |
| TW (2) | TW201639545A (https=) |
| UY (1) | UY32896A (https=) |
| WO (1) | WO2011035079A1 (https=) |
| ZA (1) | ZA201202761B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
| JP5966202B2 (ja) | 2007-02-20 | 2016-08-10 | アラガン ファーマシューティカルズ インターナショナル リミテッド | 安定な消化酵素組成物 |
| US10087493B2 (en) | 2008-03-07 | 2018-10-02 | Aptalis Pharma Canada Ulc | Method for detecting infectious parvovirus in pharmaceutical preparations |
| ES2657673T3 (es) * | 2010-10-01 | 2018-03-06 | Aptalis Pharma Limited | Formulaciones recubiertas entéricas de pancrelipasa, de baja intensidad |
| CA2843556A1 (en) * | 2011-08-08 | 2013-02-14 | Aptalis Pharma Ltd. | Method for dissolution testing of solid compositions containing digestive enzymes |
| US10184121B2 (en) | 2013-06-28 | 2019-01-22 | Allergan Pharmaceuticals International Limited | Methods for removing viral contaminants from pancreatic extracts |
| CA2920844A1 (en) | 2013-08-09 | 2015-02-12 | Allergan Pharmaceuticals International Limited | Digestive enzyme composition suitable for enteral administration |
| FR3079146B1 (fr) * | 2018-03-23 | 2020-04-17 | Karim Ioualalen | Formulation gastroprotectrice de complexes d’enzymes permettant de restaurer la fonction digestive. |
| US20230138700A1 (en) * | 2020-03-30 | 2023-05-04 | Jai WALL | Combined animal-derived and synthetically produced pancreatic enzyme replacement therapy |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1509866A (en) | 1975-06-10 | 1978-05-04 | Johnson & Johnson | Enteric coated digestive enzyme compositions |
| US4447412A (en) * | 1983-02-01 | 1984-05-08 | Bilton Gerald L | Enzyme-containing digestive aid compostions |
| US5260074A (en) | 1992-06-22 | 1993-11-09 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| US5460812A (en) | 1992-06-22 | 1995-10-24 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| US5302400A (en) | 1992-06-22 | 1994-04-12 | Digestive Care Inc. | Preparation of gastric acid-resistant microspheres containing digestive enzymes and buffered-bile acids |
| US5578304A (en) | 1992-06-22 | 1996-11-26 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| DE4227385A1 (de) | 1992-08-19 | 1994-02-24 | Kali Chemie Pharma Gmbh | Pankreatinmikropellets |
| JP2000505801A (ja) | 1996-02-09 | 2000-05-16 | クアドラント・ホールディングズ・ケンブリッジ・リミテッド | トレハロースを含む固形製剤 |
| US5750104A (en) | 1996-05-29 | 1998-05-12 | Digestive Care Inc. | High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith |
| US20010046493A1 (en) | 2000-02-24 | 2001-11-29 | Alex Margolin | Lipase-containing composition and methods of use thereof |
| CN1156308C (zh) * | 2002-04-19 | 2004-07-07 | 北京世诺医药科技有限公司 | 多酶组合胶囊 |
| US20040132826A1 (en) * | 2002-10-25 | 2004-07-08 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
| WO2004071374A2 (en) | 2003-02-11 | 2004-08-26 | Torrent Pharmaceuticals Limited | Once a day orally administered pharmaceutical compositions |
| WO2005042012A1 (en) * | 2003-10-29 | 2005-05-12 | Altus Pharmaceuticals Inc. | Non-pancreatic proteases for controlling plasma cholecystokinin (cck) concentration and for treating pain |
| US7387793B2 (en) | 2003-11-14 | 2008-06-17 | Eurand, Inc. | Modified release dosage forms of skeletal muscle relaxants |
| US7470435B2 (en) | 2003-11-17 | 2008-12-30 | Andrx Pharmaceuticals, Llc | Extended release venlafaxine formulation |
| CA2560613C (en) | 2004-03-22 | 2015-11-24 | Solvay Pharmaceuticals Gmbh | Oral pharmaceutical compositions of lipase-containing products, in particular of pancreatin, containing surfactants |
| EP1755656B1 (en) * | 2004-05-24 | 2010-07-07 | Novozymes A/S | Enzymes for pharmaceutical use |
| WO2006044529A1 (en) * | 2004-10-14 | 2006-04-27 | Altus Pharmaceuticals Inc. | Compositions containing lipase; protease and amylase for treating pancreatic insufficiency |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| CN101208429A (zh) * | 2005-06-24 | 2008-06-25 | 诺维信公司 | 用于药物用途的脂肪酶 |
| US20070025977A1 (en) | 2005-07-21 | 2007-02-01 | Mulberg Andrew E | Method of treating steatorrhea in infants |
| KR101555058B1 (ko) | 2005-07-29 | 2015-09-22 | 애보트 래버러토리즈 게엠베하 | 살균된 판크레아틴 분말의 제조방법 |
| US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
| US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
| WO2007053619A2 (en) * | 2005-11-01 | 2007-05-10 | Bio-Cat, Inc. | A composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrous as well as people suffering from pancreatic lipase insufficiency |
| AU2007267560B2 (en) * | 2006-05-26 | 2010-10-21 | Nestec S.A. | Methods of use and nutritional compositions of Touchi Extract |
| US20080199448A1 (en) * | 2007-02-16 | 2008-08-21 | Ross Mairi R | Enzyme composition for improving food digestion |
| JP5966202B2 (ja) | 2007-02-20 | 2016-08-10 | アラガン ファーマシューティカルズ インターナショナル リミテッド | 安定な消化酵素組成物 |
| US20090117180A1 (en) * | 2007-02-20 | 2009-05-07 | Giovanni Ortenzi | Stable digestive enzyme compositions |
| EP2328566A1 (en) | 2008-09-30 | 2011-06-08 | DSM IP Assets B.V. | Enzyme composition and application thereof in the treatment of pancreatic insufficiency |
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