JP2013503204A - B7−h4融合タンパク質およびその使用方法 - Google Patents

B7−h4融合タンパク質およびその使用方法 Download PDF

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JP2013503204A
JP2013503204A JP2012527101A JP2012527101A JP2013503204A JP 2013503204 A JP2013503204 A JP 2013503204A JP 2012527101 A JP2012527101 A JP 2012527101A JP 2012527101 A JP2012527101 A JP 2012527101A JP 2013503204 A JP2013503204 A JP 2013503204A
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cells
seq
fusion protein
polypeptide
subject
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JP2013503204A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
ソロモン ランガーマン,
リンダ リュー,
ジョセフ アール. ポドジル,
スティーブン ディー. ミラー,
シャノン マーシャル,
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アンプリミューン, インコーポレイテッド
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70532B7 molecules, e.g. CD80, CD86
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6866Interferon
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
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JP2012527101A 2009-08-31 2010-08-31 B7−h4融合タンパク質およびその使用方法 Pending JP2013503204A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US23860509P 2009-08-31 2009-08-31
US61/238,605 2009-08-31
US25493009P 2009-10-26 2009-10-26
US61/254,930 2009-10-26
US26685409P 2009-12-04 2009-12-04
US61/266,854 2009-12-04
US28653709P 2009-12-15 2009-12-15
US61/286,537 2009-12-15
US37836110P 2010-08-30 2010-08-30
US61/378,361 2010-08-30
PCT/US2010/047366 WO2011026122A2 (en) 2009-08-31 2010-08-31 B7-h4 fusion proteins and methods of use thereof

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JP2013503204A true JP2013503204A (ja) 2013-01-31
JP2013503204A5 JP2013503204A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2013-10-17

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JP2012527108A Pending JP2013503205A (ja) 2009-08-31 2010-08-31 移植拒絶反応を阻害するための方法および組成物
JP2012527101A Pending JP2013503204A (ja) 2009-08-31 2010-08-31 B7−h4融合タンパク質およびその使用方法

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US (4) US9005616B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP2473521A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JP2013503205A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (2) CN102741279A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU2010286351A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (2) CA2772204A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (2) IN2012DN02753A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (2) WO2011026132A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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JP2017530726A (ja) * 2014-09-25 2017-10-19 イデア オーチャード, リミテッド ライアビリティ カンパニー 抗体様タンパク質
JP2020535809A (ja) * 2017-09-29 2020-12-10 ナントセル,インコーポレイテッド 抗原タンパク質及びそのための方法

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