JP2013501033A - リポカリン突然変異タンパク質の制御放出製剤 - Google Patents
リポカリン突然変異タンパク質の制御放出製剤 Download PDFInfo
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- JP2013501033A JP2013501033A JP2012523344A JP2012523344A JP2013501033A JP 2013501033 A JP2013501033 A JP 2013501033A JP 2012523344 A JP2012523344 A JP 2012523344A JP 2012523344 A JP2012523344 A JP 2012523344A JP 2013501033 A JP2013501033 A JP 2013501033A
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- lipocalin
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- lipocalin mutein
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- mutein
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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| JP2017536387A (ja) * | 2014-12-02 | 2017-12-07 | アントリアバイオ インコーポレイテッドＡｎｔｒｉａｂｉｏ，Ｉｎｃ． | 疎水性が高められたタンパク質及びタンパク質コンジュゲート |
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| US8889193B2 (en) | 2010-02-25 | 2014-11-18 | The Johns Hopkins University | Sustained delivery of therapeutic agents to an eye compartment |
| WO2012109363A2 (en) | 2011-02-08 | 2012-08-16 | The Johns Hopkins University | Mucus penetrating gene carriers |
| US9701732B2 (en) | 2011-02-28 | 2017-07-11 | Korea University Research And Business Foundation | Fusion protein comprising albumin and retinol-binding protein |
| US9273116B2 (en) * | 2011-02-28 | 2016-03-01 | Korea University Research And Business Foundation | Fusion protein comprising albumin and retinol-binding protein |
| US10064915B2 (en) | 2011-02-28 | 2018-09-04 | Korea University Research And Business Foundation | Fusion protein comprising albumin and retinol-binding protein |
| WO2012172433A2 (en) * | 2011-06-14 | 2012-12-20 | Ipsen Pharma S.A.S. | A sustained-release composition containing peptides as active ingredient |
| WO2013068590A1 (en) * | 2011-11-11 | 2013-05-16 | Pieris Ag | Lipocalin muteins as vegf antagonists for use in treating diseases caused or promoted by increased vascularization |
| CA2860843C (en) * | 2012-01-09 | 2021-03-23 | Pieris Ag | Methods for preventing, treating or diagnosing disorders |
| JP6184982B2 (ja) | 2012-02-02 | 2017-08-23 | エスバテック − ア ノバルティス カンパニー エルエルシー | 点眼用抗体含有徐放性製剤 |
| CA2867203C (en) | 2012-03-16 | 2016-09-20 | The Johns Hopkins University | Non-linear multiblock copolymer-drug conjugates for the delivery of active agents |
| JP5883539B2 (ja) | 2012-03-16 | 2016-03-15 | ザ・ジョンズ・ホプキンス・ユニバーシティー | Ｈｉｆ−１阻害剤の送達のための放出制御製剤 |
| US9533068B2 (en) * | 2012-05-04 | 2017-01-03 | The Johns Hopkins University | Drug loaded microfiber sutures for ophthalmic application |
| US10568975B2 (en) | 2013-02-05 | 2020-02-25 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
| CN103394094B (zh) * | 2013-07-16 | 2015-05-13 | 天津大学 | 基于牛血清白蛋白-聚己内酯的高分子脂质体及其制备方法 |
| CN103360609B (zh) * | 2013-07-16 | 2015-08-19 | 天津大学 | 一种双亲性的蛋白质-高分子键合体及其制备方法 |
| AU2015205530B8 (en) | 2014-01-13 | 2019-09-19 | Pieris Pharmaceuticals Gmbh | Multi-specific polypeptide useful for localized tumor immunomodulation |
| WO2016123125A1 (en) | 2015-01-27 | 2016-08-04 | The Johns Hopkins University | Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces |
| BR112017020434A2 (pt) | 2015-05-04 | 2018-06-26 | Pieris Pharmaceuticals Gmbh | polipeptídeos de fusão, molécula de ácido nucleico, célula hospedeira, método para produzir um polipeptídeo de fusão, usos do polipeptídeo de fusão, métodos para ativar as vias de sinalização, para coestimular células, para induzir a proliferação de linfócitos t, para direcionar o agrupamento de cd137, para induzir uma resposta local de células t, para induzir uma resposta local de células nk e para induzir a produção de il-2 |
| CA3014406A1 (en) * | 2016-02-16 | 2017-08-24 | Strongbridge Biopharma plc | Veldoreotide with poor solubitliy in physiological conditions for use in the treatment of acromegaly, acromegaly cancer, sst-r5 expressing tumors, type 2 diabetes, hyperglycemia,and hormone-related tumors |
| US12496279B2 (en) | 2019-04-11 | 2025-12-16 | The Johns Hopkins University | Nanoparticles for drug delivery to brain |
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- 2010-08-05 WO PCT/EP2010/061436 patent/WO2011015634A2/en not_active Ceased
- 2010-08-05 CN CN2010800348503A patent/CN102612362A/zh active Pending
- 2010-08-05 AU AU2010280688A patent/AU2010280688A1/en not_active Abandoned
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- 2010-08-05 EP EP10747840A patent/EP2461800A2/en not_active Withdrawn
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- 2010-08-05 BR BR112012002709-3A patent/BR112012002709A2/pt not_active IP Right Cessation
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| JP2017536387A (ja) * | 2014-12-02 | 2017-12-07 | アントリアバイオ インコーポレイテッドＡｎｔｒｉａｂｉｏ，Ｉｎｃ． | 疎水性が高められたタンパク質及びタンパク質コンジュゲート |
Also Published As
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| IN2012DN00407A (cg-RX-API-DMAC7.html) | 2015-08-21 |
| EP2461800A2 (en) | 2012-06-13 |
| EP2550958B1 (en) | 2018-10-10 |
| CN106139123A (zh) | 2016-11-23 |
| WO2011015634A2 (en) | 2011-02-10 |
| AU2010280688A1 (en) | 2012-02-23 |
| JP2012255007A (ja) | 2012-12-27 |
| JP5774557B2 (ja) | 2015-09-09 |
| CA2770149A1 (en) | 2011-02-10 |
| AU2016204715A1 (en) | 2016-07-28 |
| WO2011015634A3 (en) | 2011-04-14 |
| US20120201873A1 (en) | 2012-08-09 |
| CN102612362A (zh) | 2012-07-25 |
| EP2550958A1 (en) | 2013-01-30 |
| RU2012107812A (ru) | 2013-09-10 |
| KR20120099371A (ko) | 2012-09-10 |
| BR112012002709A2 (pt) | 2019-04-30 |
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