JP2013129675A5 - - Google Patents
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- JP2013129675A5 JP2013129675A5 JP2013068780A JP2013068780A JP2013129675A5 JP 2013129675 A5 JP2013129675 A5 JP 2013129675A5 JP 2013068780 A JP2013068780 A JP 2013068780A JP 2013068780 A JP2013068780 A JP 2013068780A JP 2013129675 A5 JP2013129675 A5 JP 2013129675A5
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- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- construction
- alkyl
- compound according
- Prior art date
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- NSUHNQDDWKTVCF-ADPWAJQXSA-N CC1C(Oc2c(C)nccc2)=NC=NC1(C)OC(C[C@@H]1CC2)C[C@H]2C1NS(C1CC1)(=O)=O Chemical compound CC1C(Oc2c(C)nccc2)=NC=NC1(C)OC(C[C@@H]1CC2)C[C@H]2C1NS(C1CC1)(=O)=O NSUHNQDDWKTVCF-ADPWAJQXSA-N 0.000 description 1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98167707P | 2007-10-22 | 2007-10-22 | |
US60/981,677 | 2007-10-22 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010530173A Division JP2011500727A (ja) | 2007-10-22 | 2008-10-20 | Gpr119の活性のモジュレーターとしての二環式ヘテロ環誘導体およびその使用 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2013129675A JP2013129675A (ja) | 2013-07-04 |
JP2013129675A5 true JP2013129675A5 (US07714131-20100511-C00001.png) | 2014-01-16 |
JP5568154B2 JP5568154B2 (ja) | 2014-08-06 |
Family
ID=40352187
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010530173A Pending JP2011500727A (ja) | 2007-10-22 | 2008-10-20 | Gpr119の活性のモジュレーターとしての二環式ヘテロ環誘導体およびその使用 |
JP2013068780A Expired - Fee Related JP5568154B2 (ja) | 2007-10-22 | 2013-03-28 | Gpr119の活性のモジュレーターとしての二環式ヘテロ環誘導体およびその使用 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010530173A Pending JP2011500727A (ja) | 2007-10-22 | 2008-10-20 | Gpr119の活性のモジュレーターとしての二環式ヘテロ環誘導体およびその使用 |
Country Status (15)
Families Citing this family (51)
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FR2945531A1 (fr) * | 2009-05-12 | 2010-11-19 | Sanofi Aventis | Derives de 7-aza-spiro°3,5!nonane-7-carboxylates, leur preparation et leur application en therapeutique |
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TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
CN102432598A (zh) * | 2010-09-29 | 2012-05-02 | 江苏恒瑞医药股份有限公司 | 三环化合物、其制备方法及其在医药上的应用 |
CU24152B1 (es) | 2010-12-20 | 2016-02-29 | Irm Llc | 1,2 oxazol-8-azabiciclo[3,2,1]octano 8 il como moduladores de fxr |
EA031618B1 (ru) | 2011-06-09 | 2019-01-31 | Ризен Фармасьютикалз Са | Соединения-модуляторы gpr-119 |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
EP2780026B1 (en) | 2011-11-15 | 2019-10-23 | Merck Sharp & Dohme Corp. | Hcv ns3 protease inhibitors |
KR101705390B1 (ko) | 2012-06-25 | 2017-02-09 | 강원대학교산학협력단 | 이중환 구조를 갖는 신규한 gpcr 효능제 |
AR091739A1 (es) | 2012-07-11 | 2015-02-25 | Elcelyx Therapeutics Inc | Composiciones y metodos para reducir el riesgo cardiometabolico |
JP6546596B2 (ja) | 2013-09-26 | 2019-07-17 | カデント セラピューティクス,インコーポレーテッド | Nr2bの選択的オクタヒドロ−シクロペンタ[c]ピロール負調節因子 |
WO2016020288A1 (en) | 2014-08-04 | 2016-02-11 | Nuevolution A/S | Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases |
EP3193611B1 (en) | 2014-09-17 | 2021-03-24 | Celgene Car Llc | Mk2 inhibitors and uses thereof |
JO3579B1 (ar) | 2014-09-26 | 2020-07-05 | Luc Therapeutics Inc | مُعدِلات تفاغرية سالبة لمستقبل nr2b من المركب n-ألكيل أريل-5-أوكسي أريل-ثامن هيدرو-خماسي الحلقة [c] بيرول |
JP7212693B2 (ja) | 2017-11-01 | 2023-01-25 | ブリストル-マイヤーズ スクイブ カンパニー | ファルネソイドx受容体モジュレーターとしての架橋二環化合物 |
ES2944657T3 (es) | 2017-11-01 | 2023-06-23 | Bristol Myers Squibb Co | Compuestos de alqueno como moduladores del receptor farnesoide X |
CN111630051B (zh) | 2017-11-01 | 2023-12-26 | 百时美施贵宝公司 | 作为法尼醇x受体调节剂的烯烃螺环化合物 |
EA202091101A1 (ru) | 2017-11-01 | 2020-08-06 | Бристол-Маерс Сквибб Компани | Спироциклические соединения в качестве модуляторов фарнезоидного x-рецептора |
WO2019089664A1 (en) | 2017-11-01 | 2019-05-09 | Bristol-Myers Squibb Company | Multicyclic compounds as farnesoid x receptor modulators |
US10865194B2 (en) * | 2017-11-03 | 2020-12-15 | Fondazione Istituto Italiano Di Tecnologia | Therapeutically active bicyclic-sulphonamides and pharmaceutical compositions |
AR118050A1 (es) | 2019-02-15 | 2021-09-15 | Bristol Myers Squibb Co | Compuestos bicíclicos sustituidos como moduladores del receptor farnesoide x |
PL3966207T3 (pl) | 2019-05-10 | 2024-03-04 | Deciphera Pharmaceuticals, Llc | Fenyloaminopirymidynoamidowe inhibitory autofagii i sposoby ich zastosowania |
PE20220592A1 (es) | 2019-05-10 | 2022-04-22 | Deciphera Pharmaceuticals Llc | Inhibidores de la autofagia de heteroarilaminopirimidina amida y metodos de uso de estos |
KR20220024605A (ko) | 2019-06-17 | 2022-03-03 | 데시페라 파마슈티칼스, 엘엘씨. | 아미노피리미딘 아미드 자가포식 억제제 및 이의 사용 방법 |
EP4076657A1 (en) | 2019-12-20 | 2022-10-26 | Nuevolution A/S | Compounds active towards nuclear receptors |
CA3174176A1 (en) | 2020-03-31 | 2021-10-07 | Sanne Schroder Glad | Compounds active towards nuclear receptors |
MX2022012260A (es) | 2020-03-31 | 2022-11-30 | Nuevolution As | Compuestos activos frente a receptores nucleares. |
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IL68769A (en) | 1983-05-23 | 1986-02-28 | Hadassah Med Org | Pharmaceutical compositions containing insulin for oral administration |
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BRPI0616245A2 (pt) | 2005-09-16 | 2011-06-14 | Arena Pharm Inc | modulador de metabolismo, seus usos, composiÇço farmaceutica compreendendo o mesmo, bem como mÉtodo para produÇço da referida composiÇço |
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-
2008
- 2008-10-20 JP JP2010530173A patent/JP2011500727A/ja active Pending
- 2008-10-20 US US12/739,531 patent/US8907095B2/en active Active
- 2008-10-20 CN CN200880123287XA patent/CN101910151A/zh active Pending
- 2008-10-20 MX MX2010004450A patent/MX2010004450A/es unknown
- 2008-10-20 EP EP08832779.6A patent/EP2217596B8/en active Active
- 2008-10-20 KR KR1020107010766A patent/KR20100075643A/ko not_active Application Discontinuation
- 2008-10-20 WO PCT/US2008/080462 patent/WO2009055331A2/en active Application Filing
- 2008-10-20 AU AU2008317057A patent/AU2008317057B8/en not_active Ceased
- 2008-10-20 CA CA2703203A patent/CA2703203C/en not_active Expired - Fee Related
- 2008-10-21 TW TW097140281A patent/TW200922578A/zh unknown
- 2008-10-21 PE PE2008001811A patent/PE20091343A1/es not_active Application Discontinuation
- 2008-10-21 CL CL2008003116A patent/CL2008003116A1/es unknown
- 2008-10-21 AR ARP080104586A patent/AR068950A1/es unknown
-
2010
- 2010-04-22 IL IL205251A patent/IL205251A0/en unknown
- 2010-04-28 ZA ZA2010/02959A patent/ZA201002959B/en unknown
-
2013
- 2013-03-28 JP JP2013068780A patent/JP5568154B2/ja not_active Expired - Fee Related