|
US4107288A
(en)
|
1974-09-18 |
1978-08-15 |
Pharmaceutical Society Of Victoria |
Injectable compositions, nanoparticles useful therein, and process of manufacturing same
|
|
JPS6041077B2
(ja)
|
1976-09-06 |
1985-09-13 |
喜徳 喜谷 |
１，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
|
|
US4323581A
(en)
|
1978-07-31 |
1982-04-06 |
Johnson & Johnson |
Method of treating carcinogenesis
|
|
US4649146A
(en)
|
1983-01-31 |
1987-03-10 |
Fujisawa Pharmaceutical Co., Ltd. |
Thiazole derivatives and pharmaceutical composition comprising the same
|
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
|
GB8531637D0
(en)
|
1985-12-23 |
1986-02-05 |
Ici Plc |
Pyrimidine derivatives
|
|
DE3703435A1
(de)
|
1987-02-05 |
1988-08-18 |
Thomae Gmbh Dr K |
Neue thiazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
DE3752123T2
(de)
|
1987-03-09 |
1998-05-14 |
Kyowa Hakko Kogyo Kk |
Derivate des physiologisch aktiven mittels k-252
|
|
US4904768A
(en)
|
1987-08-04 |
1990-02-27 |
Bristol-Myers Company |
Epipodophyllotoxin glucoside 4'-phosphate derivatives
|
|
WO1989007105A1
(fr)
|
1988-02-04 |
1989-08-10 |
Kyowa Hakko Kogyo Co., Ltd. |
Derives de staurosporine
|
|
DE68916198T2
(de)
|
1988-04-15 |
1994-09-22 |
Taiho Pharmaceutical Co Ltd |
Carbamoyl-2-Pyrrolidinonverbindungen.
|
|
US5238944A
(en)
|
1988-12-15 |
1993-08-24 |
Riker Laboratories, Inc. |
Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
US5145684A
(en)
|
1991-01-25 |
1992-09-08 |
Sterling Drug Inc. |
Surface modified drug nanoparticles
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
US6410010B1
(en)
|
1992-10-13 |
2002-06-25 |
Board Of Regents, The University Of Texas System |
Recombinant P53 adenovirus compositions
|
|
US5268376A
(en)
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
WO1993007153A1
(en)
|
1991-10-10 |
1993-04-15 |
Schering Corporation |
4'-(n-substituted-n-oxide)staurosporine derivatives
|
|
US5266575A
(en)
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
|
WO1993008809A1
(en)
|
1991-11-08 |
1993-05-13 |
The University Of Southern California |
Compositions containing k-252 compounds for potentiation of neurotrophin activity
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
US5948898A
(en)
|
1992-03-16 |
1999-09-07 |
Isis Pharmaceuticals, Inc. |
Methoxyethoxy oligonucleotides for modulation of protein kinase C expression
|
|
US5756494A
(en)
|
1992-07-24 |
1998-05-26 |
Cephalon, Inc. |
Protein kinase inhibitors for treatment of neurological disorders
|
|
US5621100A
(en)
|
1992-07-24 |
1997-04-15 |
Cephalon, Inc. |
K-252a derivatives for treatment of neurological disorders
|
|
ES2225824T3
(es)
|
1992-08-31 |
2005-03-16 |
Ludwig Institute For Cancer Research |
Nonapeptido aislado derivado del gen mage-3 y presentado por hla-a1, y sus usos.
|
|
DE69331228T4
(de)
|
1992-09-21 |
2002-09-05 |
Kyowa Hakko Kogyo Co., Ltd. |
Heilmittel für thrombozytopenia
|
|
BR9207175A
(pt)
|
1992-10-28 |
1995-12-12 |
Genentech Inc |
Composição contendo antagonista de fator de crescimento de célula endotelial vascular sequência aminoácida de anticorpo monoclonal polipeptídeo e método de tratamento de tumor em mamífero
|
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
|
US5352784A
(en)
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
|
EP0708772B1
(en)
|
1993-07-15 |
2000-08-23 |
Minnesota Mining And Manufacturing Company |
IMIDAZO [4,5-c]PYRIDIN-4-AMINES
|
|
US5478932A
(en)
|
1993-12-02 |
1995-12-26 |
The Board Of Trustees Of The University Of Illinois |
Ecteinascidins
|
|
US5525812A
(en)
|
1993-12-07 |
1996-06-11 |
The United States Of America As Represented By The United States Department Of Energy |
Retractable pin dual in-line package test clip
|
|
ES2236702T3
(es)
|
1993-12-23 |
2005-07-16 |
Eli Lilly And Company |
Inhibidores de la proteina quinasa c.
|
|
US5587459A
(en)
|
1994-08-19 |
1996-12-24 |
Regents Of The University Of Minnesota |
Immunoconjugates comprising tyrosine kinase inhibitors
|
|
US6083903A
(en)
|
1994-10-28 |
2000-07-04 |
Leukosite, Inc. |
Boronic ester and acid compounds, synthesis and uses
|
|
US5482936A
(en)
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
|
MX9707453A
(es)
|
1995-03-30 |
1997-12-31 |
Pfizer |
Derivados de quinazolina.
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US6331555B1
(en)
|
1995-06-01 |
2001-12-18 |
University Of California |
Treatment of platelet derived growth factor related disorders such as cancers
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
AU6888196A
(en)
|
1995-08-11 |
1997-03-12 |
Yale University |
Glycosylated indolocarbazole synthesis
|
|
FR2741881B1
(fr)
|
1995-12-01 |
1999-07-30 |
Centre Nat Rech Scient |
Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
|
|
DE69620445T2
(de)
|
1995-12-08 |
2002-12-12 |
Janssen Pharmaceutica N.V., Beerse |
(imidazol-5-yl)methyl-2-chinolinoderivate als farnesyl protein transferase inhibitoren
|
|
KR100447918B1
(ko)
|
1996-07-25 |
2005-09-28 |
동아제약주식회사 |
대장을포함한위장관보호작용을갖는플라본및플라바논화합물
|
|
CA2262776C
(en)
|
1996-08-02 |
2005-03-08 |
Genesense Technologies, Inc. |
Antitumor antisense sequences directed against r1 and r2 components of ribonucleotide reductase
|
|
EP0946587A2
(en)
|
1996-12-16 |
1999-10-06 |
Fujisawa Pharmaceutical Co., Ltd. |
New amide compounds
|
|
US6187797B1
(en)
|
1996-12-23 |
2001-02-13 |
Dupont Pharmaceuticals Company |
Phenyl-isoxazoles as factor XA Inhibitors
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
US6126965A
(en)
|
1997-03-21 |
2000-10-03 |
Georgetown University School Of Medicine |
Liposomes containing oligonucleotides
|
|
AU744986B2
(en)
|
1997-07-12 |
2002-03-07 |
Cancer Research Technology Limited |
Cyclin dependent kinase inhibiting purine derivatives
|
|
DE69821132T2
(de)
|
1997-10-27 |
2004-10-21 |
Takeda Chemical Industries Ltd |
1,3-thiazole als adenosine a3 rezeptor antagonisten zur behandlung von asthma, allergien und diabetes
|
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
FR2777908B1
(fr)
|
1998-04-24 |
2000-12-08 |
Agronomique Inst Nat Rech |
Clonage et expression du gene de la beta-glucosidase d'origine fongique bgii
|
|
EA005032B1
(ru)
|
1998-05-29 |
2004-10-28 |
Сьюджен, Инк. |
Пирролзамещенные 2-индолиноны (варианты), фармацевтическая композиция (варианты), способ модулирования каталитической активности протеинкиназы, способ лечения или профилактики нарушения в организме, связанного с протеинкиназой
|
|
US20030083242A1
(en)
|
1998-11-06 |
2003-05-01 |
Alphonse Galdes |
Methods and compositions for treating or preventing peripheral neuropathies
|
|
CA2376596C
(en)
|
1999-06-25 |
2009-10-06 |
Genentech, Inc. |
Humanized anti-erbb2 antibodies and treatment with anti-erbb2 antibodies
|
|
IL147182A0
(en)
*
|
1999-06-30 |
2002-08-14 |
Interleukin Genetics Inc |
Diagnostics and therapeutics for diseases associated with an il-1 inflammatory haplorype
|
|
EP1201668A4
(en)
|
1999-07-13 |
2003-05-21 |
Kyowa Hakko Kogyo Kk |
Staurosporine DERIVATIVES
|
|
DE60023926T2
(de)
|
1999-09-10 |
2006-07-20 |
Merck & Co., Inc. |
Tyrosin kinase inhibitoren
|
|
CZ301689B6
(cs)
|
1999-11-05 |
2010-05-26 |
Astrazeneca Ab |
Derivát chinazolinu a farmaceutický prostredek, který ho obsahuje
|
|
SI1255752T1
(sl)
|
2000-02-15 |
2007-12-31 |
Pharmacia & Upjohn Co Llc |
S pirolom substituirani zaviralci 2-indolinon protein kinaza
|
|
EP1274705A1
(en)
|
2000-03-29 |
2003-01-15 |
Cyclacel Limited |
2-substituted 4-heteroaryl-pyrimidines and their use in the treatment of proliferative disorders
|
|
PT1274718E
(pt)
|
2000-04-12 |
2007-01-31 |
Genaera Corp |
Processo para a preparação de esteróis 7. alfa-hidroxi 3- aminosubstítuidos utilizando intermediários com um grupo 7. alfa-hidroxilo desprotegido
|
|
PL204958B1
(pl)
|
2000-06-30 |
2010-02-26 |
Glaxo Group Ltd |
Ditosylany związków chinazolinowych, środek farmaceutyczny i zastosowanie tych związków
|
|
CZ304344B6
(cs)
|
2000-09-11 |
2014-03-19 |
Novartis Vaccines & Diagnostics, Inc. |
Chinolinonový derivát a jeho použití a farmaceutický prostředek s obsahem tohoto derivátu
|
|
US6677450B2
(en)
|
2000-10-06 |
2004-01-13 |
Bristol-Myers Squibb Company |
Topoisomerase inhibitors
|
|
DE60137273D1
(de)
|
2000-10-20 |
2009-02-12 |
Eisai R&D Man Co Ltd |
Verfahren zur Herstellung von 4-Phenoxy chinolin Derivaten
|
|
US6621100B2
(en)
|
2000-10-27 |
2003-09-16 |
The Ohio State University |
Polymer-, organic-, and molecular-based spintronic devices
|
|
WO2002057423A2
(en)
|
2001-01-16 |
2002-07-25 |
Regeneron Pharmaceuticals, Inc. |
Isolating cells expressing secreted proteins
|
|
WO2002062826A1
(fr)
|
2001-02-07 |
2002-08-15 |
Vadim Viktorovich Novikov |
Procede de fabrication des peptides
|
|
EP1256578B1
(en)
|
2001-05-11 |
2006-01-11 |
Pfizer Products Inc. |
Thiazole derivatives and their use as cdk inhibitors
|
|
US20040186172A1
(en)
|
2001-07-02 |
2004-09-23 |
Houssam Ibrahim |
Oxaliplatin active substance with a very low content of oxalic acid
|
|
KR100979988B1
(ko)
|
2001-08-13 |
2010-09-03 |
얀센 파마슈티카 엔.브이. |
2-아미노-4,5-삼치환 티아졸릴 유도체
|
|
US7265134B2
(en)
|
2001-08-17 |
2007-09-04 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
KR100484504B1
(ko)
|
2001-09-18 |
2005-04-20 |
학교법인 포항공과대학교 |
쿠커비투릴 유도체를 주인 분자로서 포함하고 있는 내포화합물 및 이를 포함한 약제학적 조성물
|
|
WO2003029248A1
(en)
|
2001-09-28 |
2003-04-10 |
Cyclacel Limited |
N-(4-(4-methylthiazol-5-yl) pyrimidin-2-yl) -n-phenylamines as antiproliferative compounds
|
|
US20030134846A1
(en)
|
2001-10-09 |
2003-07-17 |
Schering Corporation |
Treatment of trypanosoma brucei with farnesyl protein transferase inhibitors
|
|
WO2003077902A1
(en)
|
2002-02-19 |
2003-09-25 |
Xenoport, Inc. |
Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
|
|
TWI314928B
(en)
|
2002-02-28 |
2009-09-21 |
Novartis A |
5-phenylthiazole derivatives and use as pi3 kinase inhibitors
|
|
NZ535985A
(en)
|
2002-03-29 |
2007-04-27 |
Chiron Corp |
Substituted benzazoles and use thereof as RAF kinase inhibitors
|
|
US6900342B2
(en)
|
2002-05-10 |
2005-05-31 |
Dabur India Limited |
Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof
|
|
US6727272B1
(en)
|
2002-07-15 |
2004-04-27 |
Unitech Pharmaceuticals, Inc. |
Leflunomide analogs for treating rheumatoid arthritis
|
|
US7148342B2
(en)
|
2002-07-24 |
2006-12-12 |
The Trustees Of The University Of Pennyslvania |
Compositions and methods for sirna inhibition of angiogenesis
|
|
EP1558607B1
(en)
|
2002-10-30 |
2010-05-05 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of rock and other protein kinases
|
|
US7632858B2
(en)
|
2002-11-15 |
2009-12-15 |
Bristol-Myers Squibb Company |
Open chain prolyl urea-related modulators of androgen receptor function
|
|
CA2511646A1
(en)
|
2002-12-27 |
2004-07-22 |
Chiron Corporation |
Thiosemicarbazones as anti-virals and immunopotentiators
|
|
ES2391770T3
(es)
|
2003-01-21 |
2012-11-29 |
Novartis Vaccines And Diagnostics, Inc. |
Uso de compuestos de triptantrina para la potenciación inmune
|
|
GB0305152D0
(en)
|
2003-03-06 |
2003-04-09 |
Novartis Ag |
Organic compounds
|
|
US7893096B2
(en)
|
2003-03-28 |
2011-02-22 |
Novartis Vaccines And Diagnostics, Inc. |
Use of small molecule compounds for immunopotentiation
|
|
US20060218641A1
(en)
|
2003-04-24 |
2006-09-28 |
Koninklijke Philips Electronics, N.V. |
Class-based content transfer between devices
|
|
TW200519106A
(en)
*
|
2003-05-02 |
2005-06-16 |
Novartis Ag |
Organic compounds
|
|
GB0320197D0
(en)
*
|
2003-08-28 |
2003-10-01 |
Novartis Ag |
Organic compounds
|
|
RU2006111093A
(ru)
|
2003-09-06 |
2007-10-27 |
Вертекс Фармасьютикалз Инкорпорейтед (Us) |
Модуляторы атр-связывающих кассетных транспортеров
|
|
DE602005001931T2
(de)
|
2004-01-12 |
2008-04-24 |
Applied Research Systems Ars Holding N.V. |
Thiazolderivate und deren verwendung
|
|
SE0402735D0
(sv)
|
2004-11-09 |
2004-11-09 |
Astrazeneca Ab |
Novel compounds
|
|
DE102005024157A1
(de)
|
2005-05-23 |
2006-11-30 |
Amedo Gmbh |
Nadelpositioniersystem
|
|
DK1885716T3
(da)
|
2005-05-24 |
2013-02-11 |
Merck Serono Sa |
Thiazolderivater og anvendelse deraf
|
|
US7655446B2
(en)
|
2005-06-28 |
2010-02-02 |
Vertex Pharmaceuticals Incorporated |
Crystal structure of Rho-kinase I kinase domain complexes and binding pockets thereof
|
|
DE102005048072A1
(de)
|
2005-09-24 |
2007-04-05 |
Bayer Cropscience Ag |
Thiazole als Fungizide
|
|
BRPI0619730A2
(pt)
|
2005-12-12 |
2011-10-11 |
Genelabs Tech Inc |
compostos antivirais de n-(anel aromático de 5 membros)-amido
|
|
GB0525671D0
(en)
|
2005-12-16 |
2006-01-25 |
Novartis Ag |
Organic compounds
|
|
AU2007206860A1
(en)
|
2006-01-23 |
2007-07-26 |
Laboratoires Serono S.A. |
Thiazole derivatives and use thereof
|
|
PE20070978A1
(es)
*
|
2006-02-14 |
2007-11-15 |
Novartis Ag |
COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE FOSFATIDILINOSITOL 3-QUINASAS (PI3Ks)
|
|
US20070259855A1
(en)
*
|
2006-04-06 |
2007-11-08 |
Udo Maier |
Thiazolyl-dihydro-indazole
|
|
GB0610243D0
(en)
*
|
2006-05-23 |
2006-07-05 |
Novartis Ag |
Organic compounds
|
|
US20080058654A1
(en)
*
|
2006-09-06 |
2008-03-06 |
Hun-Yuan Ke |
Manometer with indication label
|
|
US20080181866A1
(en)
|
2006-11-21 |
2008-07-31 |
Genelabs Technologies, Inc. |
Amido Anti-viral Compounds
|
|
WO2008124000A2
(en)
|
2007-04-02 |
2008-10-16 |
Ligand Pharmaceuticals Incorporated |
Thiazole derivatives as androgen receptor modulator compounds
|
|
GB0707087D0
(en)
*
|
2007-04-12 |
2007-05-23 |
Piramed Ltd |
Pharmaceutical compounds
|
|
TWI443090B
(zh)
|
2007-05-25 |
2014-07-01 |
Abbvie Deutschland |
作為代謝性麩胺酸受體２（ｍｇｌｕ２ 受體）之正向調節劑之雜環化合物
|
|
WO2009003009A1
(en)
|
2007-06-26 |
2008-12-31 |
Enanta Pharmaceuticals, Inc. |
Substituted pyrrolidine as anti-infectives
|
|
RS54303B1
(sr)
|
2007-07-19 |
2016-02-29 |
Lundbeck, H., A/S |
5-člani heterociklični amidi i srodna jedinjenja
|
|
EP2238134A2
(en)
|
2007-12-20 |
2010-10-13 |
Novartis AG |
Bis-thiazole derivatives, process for their preparation and their use as medicaments
|
|
EP2240475B1
(en)
|
2007-12-20 |
2013-09-25 |
Novartis AG |
Thiazole derivatives used as pi 3 kinase inhibitors
|
|
UA104147C2
(uk)
*
|
2008-09-10 |
2014-01-10 |
Новартис Аг |
Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
|
|
MX2012000178A
(es)
*
|
2009-07-02 |
2012-02-28 |
Novartis Ag |
2-carboxamida-cicloamino-ureas utiles como inhibidores de pi3k.
|