BRPI1015909A2 - 2-carboxamida cicloamino ureias substituídas - Google Patents

2-carboxamida cicloamino ureias substituídas

Info

Publication number
BRPI1015909A2
BRPI1015909A2 BRPI1015909A BRPI1015909A BRPI1015909A2 BR PI1015909 A2 BRPI1015909 A2 BR PI1015909A2 BR PI1015909 A BRPI1015909 A BR PI1015909A BR PI1015909 A BRPI1015909 A BR PI1015909A BR PI1015909 A2 BRPI1015909 A2 BR PI1015909A2
Authority
BR
Brazil
Prior art keywords
substituted ureas
carboxamide cycloamino
cycloamino
carboxamide
ureas
Prior art date
Application number
BRPI1015909A
Other languages
English (en)
Portuguese (pt)
Inventor
Gerspacher Marc
Furet Pascal
Mah Robert
Alec Fairhurst Robin
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI1015909A2 publication Critical patent/BRPI1015909A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI1015909A 2009-07-02 2010-07-01 2-carboxamida cicloamino ureias substituídas BRPI1015909A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27002909P 2009-07-02 2009-07-02
PCT/EP2010/059352 WO2011000905A1 (en) 2009-07-02 2010-07-01 Substituted 2-carboxamide cycloamino ureas

Publications (1)

Publication Number Publication Date
BRPI1015909A2 true BRPI1015909A2 (pt) 2019-09-24

Family

ID=42727680

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1015909A BRPI1015909A2 (pt) 2009-07-02 2010-07-01 2-carboxamida cicloamino ureias substituídas

Country Status (14)

Country Link
US (1) US8293753B2 (https=)
EP (1) EP2448935B1 (https=)
JP (1) JP2012531456A (https=)
KR (1) KR20120092552A (https=)
CN (1) CN102471332A (https=)
AR (1) AR077367A1 (https=)
AU (1) AU2010268019A1 (https=)
BR (1) BRPI1015909A2 (https=)
CA (1) CA2766855A1 (https=)
EA (1) EA201200086A1 (https=)
MX (1) MX2012000177A (https=)
TW (1) TW201105666A (https=)
UY (1) UY32747A (https=)
WO (1) WO2011000905A1 (https=)

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TW200519106A (en) * 2003-05-02 2005-06-16 Novartis Ag Organic compounds
EP2240475B1 (en) * 2007-12-20 2013-09-25 Novartis AG Thiazole derivatives used as pi 3 kinase inhibitors
JP6301316B2 (ja) 2012-05-23 2018-03-28 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 内胚葉細胞および肝実質細胞の組成物ならびにそれらの細胞を入手および使用する方法
SI2897644T1 (sl) * 2012-09-20 2018-10-30 Novartis Ag Farmacevtska kombinacija, ki obsega fosfatidilinozitol 3-kinazni inhibitor in aromatazni inhibitor
MA38287B1 (fr) 2013-01-23 2018-08-31 Astrazeneca Ab Nouveaux dérivés aminopyrazine pour le traitement ou la prévention du cancer
TWI687220B (zh) 2013-03-01 2020-03-11 美商英塞特控股公司 吡唑并嘧啶衍生物治療PI3Kδ相關病症之用途
TW201726140A (zh) 2015-09-17 2017-08-01 瑞典商阿斯特捷利康公司 治療癌症之新型生物標記及方法
EP3860597A4 (en) 2018-10-05 2022-08-17 Sloan-Kettering Institute for Cancer Research PI3K INHIBITORS AND USES THEREOF
AU2023366352A1 (en) * 2022-10-28 2025-05-08 Assistance Publique – Hopitaux De Paris (Aphp) New inhibitors of phosphatidylinositol 3-kinase
CN116239591B (zh) * 2023-02-14 2025-09-23 嘉兴大学 一种(4r)-磺酰氨基-l-脯氨酰胺类化合物、制备方法、应用及其药物组合
CN116987072A (zh) * 2023-07-27 2023-11-03 武汉呈瑞生物医药科技有限公司 化合物及其应用
EP4643858A1 (en) * 2024-04-29 2025-11-05 Institut National de la Santé et de la Recherche Médicale Methods and pharmaceutical composition for the treatment of uterine disease

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EP2448935B1 (en) 2015-06-24
US20110003818A1 (en) 2011-01-06
CN102471332A (zh) 2012-05-23
EA201200086A1 (ru) 2012-07-30
TW201105666A (en) 2011-02-16
MX2012000177A (es) 2012-02-28
CA2766855A1 (en) 2011-01-06
US8293753B2 (en) 2012-10-23
KR20120092552A (ko) 2012-08-21
AU2010268019A1 (en) 2012-01-19
WO2011000905A1 (en) 2011-01-06
EP2448935A1 (en) 2012-05-09
UY32747A (es) 2011-01-31
AR077367A1 (es) 2011-08-24

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