JP2012529452A5 - - Google Patents
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- Publication number
- JP2012529452A5 JP2012529452A5 JP2012514393A JP2012514393A JP2012529452A5 JP 2012529452 A5 JP2012529452 A5 JP 2012529452A5 JP 2012514393 A JP2012514393 A JP 2012514393A JP 2012514393 A JP2012514393 A JP 2012514393A JP 2012529452 A5 JP2012529452 A5 JP 2012529452A5
- Authority
- JP
- Japan
- Prior art keywords
- semi
- solid
- ala
- solid composition
- pharmaceutical product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007787 solid Substances 0.000 claims 23
- 239000008247 solid mixture Substances 0.000 claims 17
- 239000000825 pharmaceutical preparation Substances 0.000 claims 13
- 229940127557 pharmaceutical product Drugs 0.000 claims 13
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 claims 11
- 150000003626 triacylglycerols Chemical class 0.000 claims 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 9
- 239000004480 active ingredient Substances 0.000 claims 8
- 235000014113 dietary fatty acids Nutrition 0.000 claims 8
- 239000000194 fatty acid Substances 0.000 claims 8
- 229930195729 fatty acid Natural products 0.000 claims 8
- 150000004665 fatty acids Chemical class 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 230000002708 enhancing effect Effects 0.000 claims 6
- 210000000436 anus Anatomy 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 238000012377 drug delivery Methods 0.000 claims 4
- 210000003899 penis Anatomy 0.000 claims 4
- 238000002428 photodynamic therapy Methods 0.000 claims 4
- 239000001993 wax Substances 0.000 claims 4
- 239000002243 precursor Substances 0.000 claims 3
- 229920001817 Agar Polymers 0.000 claims 2
- 206010058314 Dysplasia Diseases 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 108010010803 Gelatin Proteins 0.000 claims 2
- 229920000881 Modified starch Polymers 0.000 claims 2
- 208000009608 Papillomavirus Infections Diseases 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- 229920001938 Vegetable gum Polymers 0.000 claims 2
- 239000000853 adhesive Substances 0.000 claims 2
- 230000001070 adhesive effect Effects 0.000 claims 2
- 239000008272 agar Substances 0.000 claims 2
- 235000010419 agar Nutrition 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 239000000679 carrageenan Substances 0.000 claims 2
- 229920001525 carrageenan Polymers 0.000 claims 2
- 235000010418 carrageenan Nutrition 0.000 claims 2
- 229940113118 carrageenan Drugs 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 210000003679 cervix uteri Anatomy 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 150000002191 fatty alcohols Chemical class 0.000 claims 2
- 210000004996 female reproductive system Anatomy 0.000 claims 2
- 239000008273 gelatin Substances 0.000 claims 2
- 229920000159 gelatin Polymers 0.000 claims 2
- 235000019322 gelatine Nutrition 0.000 claims 2
- 235000011852 gelatine desserts Nutrition 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 235000019426 modified starch Nutrition 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 229920001059 synthetic polymer Polymers 0.000 claims 2
- 210000001215 vagina Anatomy 0.000 claims 2
- 210000003905 vulva Anatomy 0.000 claims 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 2
- -1 5-ALA ester Chemical class 0.000 claims 1
- 206010061424 Anal cancer Diseases 0.000 claims 1
- 208000007860 Anus Neoplasms Diseases 0.000 claims 1
- 208000032271 Malignant tumor of penis Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000002471 Penile Neoplasms Diseases 0.000 claims 1
- 206010034299 Penile cancer Diseases 0.000 claims 1
- 208000006994 Precancerous Conditions Diseases 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 201000011165 anus cancer Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 230000002357 endometrial effect Effects 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 150000002334 glycols Chemical class 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 230000003232 mucoadhesive effect Effects 0.000 claims 1
- 210000004994 reproductive system Anatomy 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09251537 | 2009-06-11 | ||
| EP09251537.8 | 2009-06-11 | ||
| PCT/EP2010/003532 WO2010142457A1 (en) | 2009-06-11 | 2010-06-11 | Semi-solid compositions and pharmaceutical products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012529452A JP2012529452A (ja) | 2012-11-22 |
| JP2012529452A5 true JP2012529452A5 (https=) | 2013-08-08 |
| JP5840604B2 JP5840604B2 (ja) | 2016-01-06 |
Family
ID=41213323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514393A Active JP5840604B2 (ja) | 2009-06-11 | 2010-06-11 | 半固体組成物および医薬品 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20120136055A1 (https=) |
| EP (2) | EP3042647B1 (https=) |
| JP (1) | JP5840604B2 (https=) |
| KR (2) | KR101797780B1 (https=) |
| CN (1) | CN102458388B (https=) |
| AU (1) | AU2010257753B2 (https=) |
| CA (1) | CA2763923C (https=) |
| CL (1) | CL2011003094A1 (https=) |
| DK (1) | DK2440199T3 (https=) |
| ES (2) | ES2821831T3 (https=) |
| HU (1) | HUE026911T2 (https=) |
| MX (1) | MX2011013127A (https=) |
| NZ (1) | NZ596943A (https=) |
| PL (1) | PL2440199T3 (https=) |
| RU (1) | RU2526803C2 (https=) |
| SG (1) | SG176688A1 (https=) |
| SI (1) | SI2440199T1 (https=) |
| WO (1) | WO2010142457A1 (https=) |
| ZA (1) | ZA201109126B (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011107478A1 (en) | 2010-03-01 | 2011-09-09 | Photocure Asa | Cosmetic compositions |
| CA2804337A1 (en) | 2010-07-09 | 2012-01-12 | Photocure Asa | Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis |
| EP2794004B1 (en) | 2011-12-19 | 2020-07-29 | Photocure ASA | Irradiation apparatus |
| CN102670577B (zh) * | 2012-05-18 | 2018-04-13 | 上海复旦张江生物医药股份有限公司 | 一种光敏剂组合物、其使用方法及用途 |
| US20140067024A1 (en) | 2012-08-30 | 2014-03-06 | Photocure Asa | Dual panel photodynamic therapy lamp |
| GB201221123D0 (en) | 2012-11-23 | 2013-01-09 | Photocure As | Device for photodynamic treatment |
| CN105120839B (zh) * | 2013-02-28 | 2020-07-28 | 湖州惠中济世生物科技有限公司 | 可注射长效局麻药半固体制剂及其组成成分 |
| US10220093B2 (en) | 2013-02-28 | 2019-03-05 | Mira Pharma Corporation | Long-acting semi-solid lipid formulations |
| GB201306369D0 (en) | 2013-04-09 | 2013-05-22 | Photocure As | Irradiation device |
| US9943576B2 (en) * | 2014-04-30 | 2018-04-17 | Allergan, Inc. | Formulations of biologics for intravesical instillation |
| CZ307444B6 (cs) * | 2015-04-22 | 2018-08-29 | Jakub Rak | Mukoadhezivní polymerní film pro fotosenzitivní terapii v ústní dutině s obsahem fotosenzitizérů |
| SG11201805000RA (en) | 2015-12-17 | 2018-07-30 | Photocure Asa | Method of photodynamic therapy (pdt) for bladder cancer |
| GB201522309D0 (en) | 2015-12-17 | 2016-02-03 | Photocure Asa | Use |
| GB201522398D0 (en) | 2015-12-18 | 2016-02-03 | Photocure As | Device for photodynamic therapy |
| WO2017168416A1 (en) * | 2016-03-28 | 2017-10-05 | Vidac Pharma Ltd. | Stable pharmaceutical compositions for topical administration and uses thereof |
| US11884784B2 (en) | 2016-05-10 | 2024-01-30 | North Carolina State University | Photodynamic compositions, methods of making, and uses thereof |
| US11039616B2 (en) | 2016-05-10 | 2021-06-22 | North Carolina State University | Photodynamic compositions, methods of making, and uses thereof |
| GB2546128A (en) * | 2016-09-28 | 2017-07-12 | Photocure Asa | Pharamaceutical compositions comprising hexaminolevulinic acid and methods of using the same |
| US11453382B2 (en) * | 2017-05-01 | 2022-09-27 | Cummins Inc. | Systems and methods for controlling energy generation in a hybrid powertrain |
| DK3641882T3 (da) * | 2017-06-21 | 2023-12-18 | Photocure Asa | Fremgangsmåde til fremstilling af en flydende farmaceutisk sammensætning og indretning til anvendelse i en sådan fremgangsmåde |
| US10561606B2 (en) | 2017-12-06 | 2020-02-18 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid gel formulations |
| US11426418B2 (en) | 2017-12-06 | 2022-08-30 | Mira Pharma Corporation | Injectable long-acting semi-solid gel formulations |
| GB201808571D0 (en) * | 2018-05-24 | 2018-07-11 | Douglas Pharmaceuticals Ltd | Pharmaceutical compositions |
| BR112021004199A2 (pt) | 2018-09-07 | 2021-05-25 | R.P. Scherer Technologies, Llc | estabilização de formas de dosagem à base de lipídio sólido ou semissólido através da cura e da adição de tensoativo(s) de baixo teor de hlb |
| CA3280998A1 (en) | 2019-02-13 | 2025-10-30 | Alpheus Medical, Inc. | Non-invasive sonodynamic therapy |
| WO2020243319A1 (en) | 2019-05-29 | 2020-12-03 | Sonalasense, Inc. | Sonosensitization |
| CN110575612A (zh) * | 2019-09-27 | 2019-12-17 | 赵志国 | 女用光动力凝胶封包敷料装置 |
| CA3185803A1 (en) | 2020-08-07 | 2022-02-10 | Vijay Agarwal | Ultrasound arrays for enhanced sonodynamic therapy for treating cancer |
| WO2025190314A1 (en) * | 2024-03-12 | 2025-09-18 | Asieris Pharmaceuticals (Shanghai) Co., Ltd. | Photodynamic therapy for a cervix disorder or condition |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5234957A (en) * | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| MX9504023A (es) * | 1994-09-20 | 1997-05-31 | Johnson & Johnson | Composicion farmaceutica y transdermicamente activa que contiene acido 5-aminolaevulinico y procedimiento para su preparacion. |
| HU225148B1 (en) | 1995-03-10 | 2006-07-28 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy or diagnosis, products and kits comprising thereof and method of in vitro diagnosis by their using |
| US7530461B2 (en) * | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| JP2000502044A (ja) * | 1995-08-14 | 2000-02-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 緑色ポルフィリンを用いた光力学療法による子宮内膜の切除 |
| DE10003620A1 (de) * | 2000-01-28 | 2001-08-02 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln |
| US20020132035A1 (en) * | 2001-01-10 | 2002-09-19 | Dov Tamarkin | Synthetic fat composition |
| GB0018527D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Composition |
| GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| GB0118251D0 (en) | 2001-07-26 | 2001-09-19 | Photocure Asa | Method |
| US7264629B2 (en) * | 2001-11-09 | 2007-09-04 | Qlt, Inc. | Photodynamic therapy for the treatment of hair loss |
| EP1312353A1 (en) | 2001-11-16 | 2003-05-21 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for hair removal |
| US20040009212A1 (en) * | 2002-01-30 | 2004-01-15 | Pharma Power Biotec Co. Ltd. | Mucoadhesive thermoresponsive medicament-carrier composition |
| CA2457214A1 (en) * | 2004-02-06 | 2005-08-06 | Qlt Inc. | Photodynamic therapy for the treatment of acne |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
| GB0424833D0 (en) | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
| DE102005019628A1 (de) * | 2005-04-26 | 2006-11-09 | Technische Universität Braunschweig | Formulierung zur dermalen Anwendung |
| GB0700580D0 (en) * | 2007-01-11 | 2007-02-21 | Photocure Asa | Use |
| GB0724279D0 (en) | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
| GB0900461D0 (en) | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
-
2010
- 2010-06-11 SI SI201031166A patent/SI2440199T1/sl unknown
- 2010-06-11 KR KR1020127000600A patent/KR101797780B1/ko active Active
- 2010-06-11 EP EP16156371.3A patent/EP3042647B1/en active Active
- 2010-06-11 PL PL10724715.7T patent/PL2440199T3/pl unknown
- 2010-06-11 JP JP2012514393A patent/JP5840604B2/ja active Active
- 2010-06-11 MX MX2011013127A patent/MX2011013127A/es unknown
- 2010-06-11 WO PCT/EP2010/003532 patent/WO2010142457A1/en not_active Ceased
- 2010-06-11 KR KR1020177027346A patent/KR20170116198A/ko not_active Ceased
- 2010-06-11 CA CA2763923A patent/CA2763923C/en active Active
- 2010-06-11 SG SG2011090057A patent/SG176688A1/en unknown
- 2010-06-11 RU RU2011150919/15A patent/RU2526803C2/ru active
- 2010-06-11 DK DK10724715.7T patent/DK2440199T3/en active
- 2010-06-11 EP EP10724715.7A patent/EP2440199B1/en not_active Not-in-force
- 2010-06-11 ES ES16156371T patent/ES2821831T3/es active Active
- 2010-06-11 HU HUE10724715A patent/HUE026911T2/en unknown
- 2010-06-11 CN CN201080025639.5A patent/CN102458388B/zh active Active
- 2010-06-11 AU AU2010257753A patent/AU2010257753B2/en active Active
- 2010-06-11 NZ NZ596943A patent/NZ596943A/xx unknown
- 2010-06-11 US US13/377,722 patent/US20120136055A1/en not_active Abandoned
- 2010-06-11 ES ES10724715.7T patent/ES2573085T3/es active Active
-
2011
- 2011-12-06 CL CL2011003094A patent/CL2011003094A1/es unknown
- 2011-12-12 ZA ZA2011/09126A patent/ZA201109126B/en unknown
-
2015
- 2015-05-08 US US14/707,639 patent/US9326964B2/en active Active
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