JP2012529452A5 - - Google Patents
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- Publication number
- JP2012529452A5 JP2012529452A5 JP2012514393A JP2012514393A JP2012529452A5 JP 2012529452 A5 JP2012529452 A5 JP 2012529452A5 JP 2012514393 A JP2012514393 A JP 2012514393A JP 2012514393 A JP2012514393 A JP 2012514393A JP 2012529452 A5 JP2012529452 A5 JP 2012529452A5
- Authority
- JP
- Japan
- Prior art keywords
- semi
- solid
- ala
- solid composition
- pharmaceutical product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007787 solid Substances 0.000 claims 23
- 239000008247 solid mixture Substances 0.000 claims 17
- 239000000825 pharmaceutical preparation Substances 0.000 claims 13
- 229940127557 pharmaceutical product Drugs 0.000 claims 13
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 claims 11
- 150000003626 triacylglycerols Chemical class 0.000 claims 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 9
- 239000004480 active ingredient Substances 0.000 claims 8
- 235000014113 dietary fatty acids Nutrition 0.000 claims 8
- 239000000194 fatty acid Substances 0.000 claims 8
- 229930195729 fatty acid Natural products 0.000 claims 8
- 150000004665 fatty acids Chemical class 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 230000002708 enhancing effect Effects 0.000 claims 6
- 210000000436 anus Anatomy 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 238000012377 drug delivery Methods 0.000 claims 4
- 210000003899 penis Anatomy 0.000 claims 4
- 238000002428 photodynamic therapy Methods 0.000 claims 4
- 239000001993 wax Substances 0.000 claims 4
- 239000002243 precursor Substances 0.000 claims 3
- 229920001817 Agar Polymers 0.000 claims 2
- 206010058314 Dysplasia Diseases 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 108010010803 Gelatin Proteins 0.000 claims 2
- 229920000881 Modified starch Polymers 0.000 claims 2
- 208000009608 Papillomavirus Infections Diseases 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- 229920001938 Vegetable gum Polymers 0.000 claims 2
- 239000000853 adhesive Substances 0.000 claims 2
- 230000001070 adhesive effect Effects 0.000 claims 2
- 239000008272 agar Substances 0.000 claims 2
- 235000010419 agar Nutrition 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 239000000679 carrageenan Substances 0.000 claims 2
- 229920001525 carrageenan Polymers 0.000 claims 2
- 235000010418 carrageenan Nutrition 0.000 claims 2
- 229940113118 carrageenan Drugs 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 210000003679 cervix uteri Anatomy 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 150000002191 fatty alcohols Chemical class 0.000 claims 2
- 210000004996 female reproductive system Anatomy 0.000 claims 2
- 239000008273 gelatin Substances 0.000 claims 2
- 229920000159 gelatin Polymers 0.000 claims 2
- 235000019322 gelatine Nutrition 0.000 claims 2
- 235000011852 gelatine desserts Nutrition 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 235000019426 modified starch Nutrition 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 229920001059 synthetic polymer Polymers 0.000 claims 2
- 210000001215 vagina Anatomy 0.000 claims 2
- 210000003905 vulva Anatomy 0.000 claims 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 2
- -1 5-ALA ester Chemical class 0.000 claims 1
- 206010061424 Anal cancer Diseases 0.000 claims 1
- 208000007860 Anus Neoplasms Diseases 0.000 claims 1
- 208000032271 Malignant tumor of penis Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000002471 Penile Neoplasms Diseases 0.000 claims 1
- 206010034299 Penile cancer Diseases 0.000 claims 1
- 208000006994 Precancerous Conditions Diseases 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 201000011165 anus cancer Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 230000002357 endometrial effect Effects 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 150000002334 glycols Chemical class 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 230000003232 mucoadhesive effect Effects 0.000 claims 1
- 210000004994 reproductive system Anatomy 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09251537 | 2009-06-11 | ||
| EP09251537.8 | 2009-06-11 | ||
| PCT/EP2010/003532 WO2010142457A1 (en) | 2009-06-11 | 2010-06-11 | Semi-solid compositions and pharmaceutical products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012529452A JP2012529452A (ja) | 2012-11-22 |
| JP2012529452A5 true JP2012529452A5 (https=) | 2013-08-08 |
| JP5840604B2 JP5840604B2 (ja) | 2016-01-06 |
Family
ID=41213323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514393A Active JP5840604B2 (ja) | 2009-06-11 | 2010-06-11 | 半固体組成物および医薬品 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20120136055A1 (https=) |
| EP (2) | EP2440199B1 (https=) |
| JP (1) | JP5840604B2 (https=) |
| KR (2) | KR101797780B1 (https=) |
| CN (1) | CN102458388B (https=) |
| AU (1) | AU2010257753B2 (https=) |
| CA (1) | CA2763923C (https=) |
| CL (1) | CL2011003094A1 (https=) |
| DK (1) | DK2440199T3 (https=) |
| ES (2) | ES2821831T3 (https=) |
| HU (1) | HUE026911T2 (https=) |
| MX (1) | MX2011013127A (https=) |
| NZ (1) | NZ596943A (https=) |
| PL (1) | PL2440199T3 (https=) |
| RU (1) | RU2526803C2 (https=) |
| SG (1) | SG176688A1 (https=) |
| SI (1) | SI2440199T1 (https=) |
| WO (1) | WO2010142457A1 (https=) |
| ZA (1) | ZA201109126B (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2790827A1 (en) * | 2010-03-01 | 2011-09-09 | Photocure Asa | Cosmetic compositions |
| JP5991970B2 (ja) | 2010-07-09 | 2016-09-14 | フォトキュア エイエスエイ | 光力学的治療または光力学的診断で使用する乾燥組成物および当該乾燥組成物を含む装置 |
| RU2615870C2 (ru) | 2011-12-19 | 2017-04-11 | ФотоКьюэр АСА | Устройство облучения |
| CN102670577B (zh) * | 2012-05-18 | 2018-04-13 | 上海复旦张江生物医药股份有限公司 | 一种光敏剂组合物、其使用方法及用途 |
| US20140067024A1 (en) | 2012-08-30 | 2014-03-06 | Photocure Asa | Dual panel photodynamic therapy lamp |
| GB201221123D0 (en) | 2012-11-23 | 2013-01-09 | Photocure As | Device for photodynamic treatment |
| US10220093B2 (en) | 2013-02-28 | 2019-03-05 | Mira Pharma Corporation | Long-acting semi-solid lipid formulations |
| JP6363115B2 (ja) * | 2013-02-28 | 2018-07-25 | ミラ ファーマ コーポレイション | 注射可能局所麻酔半固体製剤およびその組成物 |
| GB201306369D0 (en) | 2013-04-09 | 2013-05-22 | Photocure As | Irradiation device |
| AU2015253045B2 (en) * | 2014-04-30 | 2020-07-16 | Allergan, Inc. | Formulations of biologics for intravesical instillation |
| CZ307444B6 (cs) * | 2015-04-22 | 2018-08-29 | Jakub Rak | Mukoadhezivní polymerní film pro fotosenzitivní terapii v ústní dutině s obsahem fotosenzitizérů |
| BR112018011965A2 (pt) | 2015-12-17 | 2018-12-04 | Photocure Asa | método de terapia fotodinâmica (pdt) para câncer de bexiga |
| GB201522309D0 (en) | 2015-12-17 | 2016-02-03 | Photocure Asa | Use |
| GB201522398D0 (en) | 2015-12-18 | 2016-02-03 | Photocure As | Device for photodynamic therapy |
| WO2017168416A1 (en) * | 2016-03-28 | 2017-10-05 | Vidac Pharma Ltd. | Stable pharmaceutical compositions for topical administration and uses thereof |
| US11884784B2 (en) | 2016-05-10 | 2024-01-30 | North Carolina State University | Photodynamic compositions, methods of making, and uses thereof |
| WO2017196961A1 (en) * | 2016-05-10 | 2017-11-16 | North Carolina State University | Photodynamic compositions, methods of making, and uses thereof |
| GB2546128A (en) * | 2016-09-28 | 2017-07-12 | Photocure Asa | Pharamaceutical compositions comprising hexaminolevulinic acid and methods of using the same |
| EP4299395B1 (en) * | 2017-05-01 | 2025-10-15 | Cummins, Inc. | System and method for controlling energy generation in a hybrid powertrain |
| DK3641882T3 (da) * | 2017-06-21 | 2023-12-18 | Photocure Asa | Fremgangsmåde til fremstilling af en flydende farmaceutisk sammensætning og indretning til anvendelse i en sådan fremgangsmåde |
| US11426418B2 (en) | 2017-12-06 | 2022-08-30 | Mira Pharma Corporation | Injectable long-acting semi-solid gel formulations |
| US10561606B2 (en) | 2017-12-06 | 2020-02-18 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid gel formulations |
| GB201808571D0 (en) * | 2018-05-24 | 2018-07-11 | Douglas Pharmaceuticals Ltd | Pharmaceutical compositions |
| EP3846852A4 (en) | 2018-09-07 | 2022-06-15 | R.P. Scherer Technologies, LLC | Solid or semisolid lipid based dosage form stabilization through curing and addition of low hlb surfactant(s) |
| IL285384B2 (en) | 2019-02-13 | 2024-11-01 | Alpheus Medical Inc | Non-invasive sonodynamic therapy |
| MX2021014512A (es) | 2019-05-29 | 2022-02-11 | Sonalasense Inc | Sonosensibilizacion. |
| CN110575612A (zh) * | 2019-09-27 | 2019-12-17 | 赵志国 | 女用光动力凝胶封包敷料装置 |
| WO2022032283A2 (en) | 2020-08-07 | 2022-02-10 | Alpheus Medical, Inc. | Ultrasound arrays for enhanced sonodynamic therapy for treating cancer |
| TW202600126A (zh) * | 2024-03-12 | 2026-01-01 | 大陸商上海亞虹醫藥科技有限公司 | 用於子宮頸疾病或病症之光動力療法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5234957A (en) * | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| JPH08175986A (ja) * | 1994-09-20 | 1996-07-09 | Johnson & Johnson Medical Inc | 経皮活性を示す５−アミノレブリン酸含有薬学組成物 |
| US7530461B2 (en) * | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| ATE202076T1 (de) | 1995-03-10 | 2001-06-15 | Photocure Asa | Ester der 5-aminolevulinsäure als mittel zur photosensibilisierung in der chemotherapie |
| EP0844876A4 (en) * | 1995-08-14 | 1999-12-01 | Univ California | ENDOMETRIAL ABLATION USING PHOTODYNAMIC TREATMENT WITH GREEN PORPHYRINS |
| DE10003620A1 (de) * | 2000-01-28 | 2001-08-02 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln |
| US20020132035A1 (en) * | 2001-01-10 | 2002-09-19 | Dov Tamarkin | Synthetic fat composition |
| GB0018527D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Composition |
| GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| GB0118251D0 (en) | 2001-07-26 | 2001-09-19 | Photocure Asa | Method |
| US7264629B2 (en) * | 2001-11-09 | 2007-09-04 | Qlt, Inc. | Photodynamic therapy for the treatment of hair loss |
| EP1312353A1 (en) | 2001-11-16 | 2003-05-21 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for hair removal |
| US20040009212A1 (en) * | 2002-01-30 | 2004-01-15 | Pharma Power Biotec Co. Ltd. | Mucoadhesive thermoresponsive medicament-carrier composition |
| CA2457214A1 (en) * | 2004-02-06 | 2005-08-06 | Qlt Inc. | Photodynamic therapy for the treatment of acne |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
| GB0424833D0 (en) | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
| DE102005019628A1 (de) * | 2005-04-26 | 2006-11-09 | Technische Universität Braunschweig | Formulierung zur dermalen Anwendung |
| GB0700580D0 (en) * | 2007-01-11 | 2007-02-21 | Photocure Asa | Use |
| GB0724279D0 (en) | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
| GB0900461D0 (en) | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
-
2010
- 2010-06-11 RU RU2011150919/15A patent/RU2526803C2/ru active
- 2010-06-11 SI SI201031166A patent/SI2440199T1/sl unknown
- 2010-06-11 SG SG2011090057A patent/SG176688A1/en unknown
- 2010-06-11 KR KR1020127000600A patent/KR101797780B1/ko active Active
- 2010-06-11 NZ NZ596943A patent/NZ596943A/xx unknown
- 2010-06-11 KR KR1020177027346A patent/KR20170116198A/ko not_active Ceased
- 2010-06-11 JP JP2012514393A patent/JP5840604B2/ja active Active
- 2010-06-11 AU AU2010257753A patent/AU2010257753B2/en active Active
- 2010-06-11 PL PL10724715.7T patent/PL2440199T3/pl unknown
- 2010-06-11 WO PCT/EP2010/003532 patent/WO2010142457A1/en not_active Ceased
- 2010-06-11 ES ES16156371T patent/ES2821831T3/es active Active
- 2010-06-11 MX MX2011013127A patent/MX2011013127A/es unknown
- 2010-06-11 ES ES10724715.7T patent/ES2573085T3/es active Active
- 2010-06-11 DK DK10724715.7T patent/DK2440199T3/en active
- 2010-06-11 US US13/377,722 patent/US20120136055A1/en not_active Abandoned
- 2010-06-11 EP EP10724715.7A patent/EP2440199B1/en not_active Not-in-force
- 2010-06-11 EP EP16156371.3A patent/EP3042647B1/en active Active
- 2010-06-11 CA CA2763923A patent/CA2763923C/en active Active
- 2010-06-11 CN CN201080025639.5A patent/CN102458388B/zh active Active
- 2010-06-11 HU HUE10724715A patent/HUE026911T2/en unknown
-
2011
- 2011-12-06 CL CL2011003094A patent/CL2011003094A1/es unknown
- 2011-12-12 ZA ZA2011/09126A patent/ZA201109126B/en unknown
-
2015
- 2015-05-08 US US14/707,639 patent/US9326964B2/en active Active
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