CL2011003094A1 - Composicion farmaceutica semi-solida libre de agua que comprende a) un ester del acido 5-aminolevulinico (5-ala) o una sal del mismo, b) uno o mas trigliceridos y c) opcionalmente uno o mas potenciadores de viscosidad; kit farmaceutico; y su uso en el tratamiento fotodinamico del cancer, condiciones pre-cancerosas y no cancerosas asociadas a hpv. - Google Patents
Composicion farmaceutica semi-solida libre de agua que comprende a) un ester del acido 5-aminolevulinico (5-ala) o una sal del mismo, b) uno o mas trigliceridos y c) opcionalmente uno o mas potenciadores de viscosidad; kit farmaceutico; y su uso en el tratamiento fotodinamico del cancer, condiciones pre-cancerosas y no cancerosas asociadas a hpv.Info
- Publication number
- CL2011003094A1 CL2011003094A1 CL2011003094A CL2011003094A CL2011003094A1 CL 2011003094 A1 CL2011003094 A1 CL 2011003094A1 CL 2011003094 A CL2011003094 A CL 2011003094A CL 2011003094 A CL2011003094 A CL 2011003094A CL 2011003094 A1 CL2011003094 A1 CL 2011003094A1
- Authority
- CL
- Chile
- Prior art keywords
- cancerous
- ala
- hpv
- triglycerides
- cancer
- Prior art date
Links
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 239000003623 enhancer Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002428 photodynamic therapy Methods 0.000 title abstract 2
- 150000003626 triacylglycerols Chemical class 0.000 title abstract 2
- 229960002749 aminolevulinic acid Drugs 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 239000007787 solid Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09251537 | 2009-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2011003094A1 true CL2011003094A1 (es) | 2012-07-20 |
Family
ID=41213323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2011003094A CL2011003094A1 (es) | 2009-06-11 | 2011-12-06 | Composicion farmaceutica semi-solida libre de agua que comprende a) un ester del acido 5-aminolevulinico (5-ala) o una sal del mismo, b) uno o mas trigliceridos y c) opcionalmente uno o mas potenciadores de viscosidad; kit farmaceutico; y su uso en el tratamiento fotodinamico del cancer, condiciones pre-cancerosas y no cancerosas asociadas a hpv. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20120136055A1 (https=) |
| EP (2) | EP2440199B1 (https=) |
| JP (1) | JP5840604B2 (https=) |
| KR (2) | KR101797780B1 (https=) |
| CN (1) | CN102458388B (https=) |
| AU (1) | AU2010257753B2 (https=) |
| CA (1) | CA2763923C (https=) |
| CL (1) | CL2011003094A1 (https=) |
| DK (1) | DK2440199T3 (https=) |
| ES (2) | ES2821831T3 (https=) |
| HU (1) | HUE026911T2 (https=) |
| MX (1) | MX2011013127A (https=) |
| NZ (1) | NZ596943A (https=) |
| PL (1) | PL2440199T3 (https=) |
| RU (1) | RU2526803C2 (https=) |
| SG (1) | SG176688A1 (https=) |
| SI (1) | SI2440199T1 (https=) |
| WO (1) | WO2010142457A1 (https=) |
| ZA (1) | ZA201109126B (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2790827A1 (en) * | 2010-03-01 | 2011-09-09 | Photocure Asa | Cosmetic compositions |
| JP5991970B2 (ja) | 2010-07-09 | 2016-09-14 | フォトキュア エイエスエイ | 光力学的治療または光力学的診断で使用する乾燥組成物および当該乾燥組成物を含む装置 |
| RU2615870C2 (ru) | 2011-12-19 | 2017-04-11 | ФотоКьюэр АСА | Устройство облучения |
| CN102670577B (zh) * | 2012-05-18 | 2018-04-13 | 上海复旦张江生物医药股份有限公司 | 一种光敏剂组合物、其使用方法及用途 |
| US20140067024A1 (en) | 2012-08-30 | 2014-03-06 | Photocure Asa | Dual panel photodynamic therapy lamp |
| GB201221123D0 (en) | 2012-11-23 | 2013-01-09 | Photocure As | Device for photodynamic treatment |
| US10220093B2 (en) | 2013-02-28 | 2019-03-05 | Mira Pharma Corporation | Long-acting semi-solid lipid formulations |
| JP6363115B2 (ja) * | 2013-02-28 | 2018-07-25 | ミラ ファーマ コーポレイション | 注射可能局所麻酔半固体製剤およびその組成物 |
| GB201306369D0 (en) | 2013-04-09 | 2013-05-22 | Photocure As | Irradiation device |
| AU2015253045B2 (en) * | 2014-04-30 | 2020-07-16 | Allergan, Inc. | Formulations of biologics for intravesical instillation |
| CZ307444B6 (cs) * | 2015-04-22 | 2018-08-29 | Jakub Rak | Mukoadhezivní polymerní film pro fotosenzitivní terapii v ústní dutině s obsahem fotosenzitizérů |
| BR112018011965A2 (pt) | 2015-12-17 | 2018-12-04 | Photocure Asa | método de terapia fotodinâmica (pdt) para câncer de bexiga |
| GB201522309D0 (en) | 2015-12-17 | 2016-02-03 | Photocure Asa | Use |
| GB201522398D0 (en) | 2015-12-18 | 2016-02-03 | Photocure As | Device for photodynamic therapy |
| WO2017168416A1 (en) * | 2016-03-28 | 2017-10-05 | Vidac Pharma Ltd. | Stable pharmaceutical compositions for topical administration and uses thereof |
| US11884784B2 (en) | 2016-05-10 | 2024-01-30 | North Carolina State University | Photodynamic compositions, methods of making, and uses thereof |
| WO2017196961A1 (en) * | 2016-05-10 | 2017-11-16 | North Carolina State University | Photodynamic compositions, methods of making, and uses thereof |
| GB2546128A (en) * | 2016-09-28 | 2017-07-12 | Photocure Asa | Pharamaceutical compositions comprising hexaminolevulinic acid and methods of using the same |
| EP4299395B1 (en) * | 2017-05-01 | 2025-10-15 | Cummins, Inc. | System and method for controlling energy generation in a hybrid powertrain |
| DK3641882T3 (da) * | 2017-06-21 | 2023-12-18 | Photocure Asa | Fremgangsmåde til fremstilling af en flydende farmaceutisk sammensætning og indretning til anvendelse i en sådan fremgangsmåde |
| US11426418B2 (en) | 2017-12-06 | 2022-08-30 | Mira Pharma Corporation | Injectable long-acting semi-solid gel formulations |
| US10561606B2 (en) | 2017-12-06 | 2020-02-18 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid gel formulations |
| GB201808571D0 (en) * | 2018-05-24 | 2018-07-11 | Douglas Pharmaceuticals Ltd | Pharmaceutical compositions |
| EP3846852A4 (en) | 2018-09-07 | 2022-06-15 | R.P. Scherer Technologies, LLC | Solid or semisolid lipid based dosage form stabilization through curing and addition of low hlb surfactant(s) |
| IL285384B2 (en) | 2019-02-13 | 2024-11-01 | Alpheus Medical Inc | Non-invasive sonodynamic therapy |
| MX2021014512A (es) | 2019-05-29 | 2022-02-11 | Sonalasense Inc | Sonosensibilizacion. |
| CN110575612A (zh) * | 2019-09-27 | 2019-12-17 | 赵志国 | 女用光动力凝胶封包敷料装置 |
| WO2022032283A2 (en) | 2020-08-07 | 2022-02-10 | Alpheus Medical, Inc. | Ultrasound arrays for enhanced sonodynamic therapy for treating cancer |
| TW202600126A (zh) * | 2024-03-12 | 2026-01-01 | 大陸商上海亞虹醫藥科技有限公司 | 用於子宮頸疾病或病症之光動力療法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5234957A (en) * | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| JPH08175986A (ja) * | 1994-09-20 | 1996-07-09 | Johnson & Johnson Medical Inc | 経皮活性を示す５−アミノレブリン酸含有薬学組成物 |
| US7530461B2 (en) * | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| ATE202076T1 (de) | 1995-03-10 | 2001-06-15 | Photocure Asa | Ester der 5-aminolevulinsäure als mittel zur photosensibilisierung in der chemotherapie |
| EP0844876A4 (en) * | 1995-08-14 | 1999-12-01 | Univ California | ENDOMETRIAL ABLATION USING PHOTODYNAMIC TREATMENT WITH GREEN PORPHYRINS |
| DE10003620A1 (de) * | 2000-01-28 | 2001-08-02 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln |
| US20020132035A1 (en) * | 2001-01-10 | 2002-09-19 | Dov Tamarkin | Synthetic fat composition |
| GB0018527D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Composition |
| GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| GB0118251D0 (en) | 2001-07-26 | 2001-09-19 | Photocure Asa | Method |
| US7264629B2 (en) * | 2001-11-09 | 2007-09-04 | Qlt, Inc. | Photodynamic therapy for the treatment of hair loss |
| EP1312353A1 (en) | 2001-11-16 | 2003-05-21 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for hair removal |
| US20040009212A1 (en) * | 2002-01-30 | 2004-01-15 | Pharma Power Biotec Co. Ltd. | Mucoadhesive thermoresponsive medicament-carrier composition |
| CA2457214A1 (en) * | 2004-02-06 | 2005-08-06 | Qlt Inc. | Photodynamic therapy for the treatment of acne |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
| GB0424833D0 (en) | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
| DE102005019628A1 (de) * | 2005-04-26 | 2006-11-09 | Technische Universität Braunschweig | Formulierung zur dermalen Anwendung |
| GB0700580D0 (en) * | 2007-01-11 | 2007-02-21 | Photocure Asa | Use |
| GB0724279D0 (en) | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
| GB0900461D0 (en) | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
-
2010
- 2010-06-11 RU RU2011150919/15A patent/RU2526803C2/ru active
- 2010-06-11 SI SI201031166A patent/SI2440199T1/sl unknown
- 2010-06-11 SG SG2011090057A patent/SG176688A1/en unknown
- 2010-06-11 KR KR1020127000600A patent/KR101797780B1/ko active Active
- 2010-06-11 NZ NZ596943A patent/NZ596943A/xx unknown
- 2010-06-11 KR KR1020177027346A patent/KR20170116198A/ko not_active Ceased
- 2010-06-11 JP JP2012514393A patent/JP5840604B2/ja active Active
- 2010-06-11 AU AU2010257753A patent/AU2010257753B2/en active Active
- 2010-06-11 PL PL10724715.7T patent/PL2440199T3/pl unknown
- 2010-06-11 WO PCT/EP2010/003532 patent/WO2010142457A1/en not_active Ceased
- 2010-06-11 ES ES16156371T patent/ES2821831T3/es active Active
- 2010-06-11 MX MX2011013127A patent/MX2011013127A/es unknown
- 2010-06-11 ES ES10724715.7T patent/ES2573085T3/es active Active
- 2010-06-11 DK DK10724715.7T patent/DK2440199T3/en active
- 2010-06-11 US US13/377,722 patent/US20120136055A1/en not_active Abandoned
- 2010-06-11 EP EP10724715.7A patent/EP2440199B1/en not_active Not-in-force
- 2010-06-11 EP EP16156371.3A patent/EP3042647B1/en active Active
- 2010-06-11 CA CA2763923A patent/CA2763923C/en active Active
- 2010-06-11 CN CN201080025639.5A patent/CN102458388B/zh active Active
- 2010-06-11 HU HUE10724715A patent/HUE026911T2/en unknown
-
2011
- 2011-12-06 CL CL2011003094A patent/CL2011003094A1/es unknown
- 2011-12-12 ZA ZA2011/09126A patent/ZA201109126B/en unknown
-
2015
- 2015-05-08 US US14/707,639 patent/US9326964B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3042647A1 (en) | 2016-07-13 |
| AU2010257753A1 (en) | 2012-01-12 |
| CA2763923C (en) | 2016-09-13 |
| CN102458388A (zh) | 2012-05-16 |
| CA2763923A1 (en) | 2010-12-16 |
| RU2526803C2 (ru) | 2014-08-27 |
| KR20170116198A (ko) | 2017-10-18 |
| MX2011013127A (es) | 2012-02-21 |
| JP5840604B2 (ja) | 2016-01-06 |
| NZ596943A (en) | 2013-09-27 |
| WO2010142457A1 (en) | 2010-12-16 |
| HUE026911T2 (en) | 2016-07-28 |
| AU2010257753B2 (en) | 2014-09-18 |
| KR20120046155A (ko) | 2012-05-09 |
| KR101797780B1 (ko) | 2017-11-14 |
| EP2440199B1 (en) | 2016-04-13 |
| ES2821831T3 (es) | 2021-04-27 |
| SI2440199T1 (sl) | 2016-05-31 |
| JP2012529452A (ja) | 2012-11-22 |
| US20150238457A1 (en) | 2015-08-27 |
| BRPI1010761A2 (pt) | 2016-03-22 |
| PL2440199T3 (pl) | 2016-10-31 |
| EP2440199A1 (en) | 2012-04-18 |
| US20120136055A1 (en) | 2012-05-31 |
| EP3042647B1 (en) | 2020-08-26 |
| ZA201109126B (en) | 2013-02-27 |
| SG176688A1 (en) | 2012-01-30 |
| CN102458388B (zh) | 2016-09-28 |
| DK2440199T3 (en) | 2016-05-17 |
| HK1164163A1 (zh) | 2012-09-21 |
| RU2011150919A (ru) | 2013-07-20 |
| ES2573085T3 (es) | 2016-06-06 |
| US9326964B2 (en) | 2016-05-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CL2011003094A1 (es) | Composicion farmaceutica semi-solida libre de agua que comprende a) un ester del acido 5-aminolevulinico (5-ala) o una sal del mismo, b) uno o mas trigliceridos y c) opcionalmente uno o mas potenciadores de viscosidad; kit farmaceutico; y su uso en el tratamiento fotodinamico del cancer, condiciones pre-cancerosas y no cancerosas asociadas a hpv. | |
| PH12012502016A1 (en) | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same | |
| CL2010000935A1 (es) | Compuestos derivados de niacina unida a un acido graso; composicion farmaceutica que los comprende; y su uso para tratar una enfermedad metabolica tal como hipertrigliceridemia, hipercolesterolemia, diabetes tipo 2 y retinopatia diabetica. | |
| CL2008001123A1 (es) | Compuestos derivados de acido lipoico; formulacion farmaceutica que lo comprende; y uso en el tratamiento del cancer. | |
| ES2488407T3 (es) | Preparación farmacéutica que contiene lipasa de origen bacteriano | |
| CU20110246A7 (es) | Ácido benzoico, derivados de ácido benzoico y conjugados de ácido heteroaril carboxílico de hidrocodona, profármacos, métodos para elaborar y utilizar los mismos | |
| CL2011003115A1 (es) | Producto farmaceutico solido para el diagnostico del cancer, afecciones precancerosas y afecciones no cancerosas en el tracto gastrointestinal inferior que comprende a) acido 5-aminolevulinico (5-ala), un precursor de 5-ala o un derivado de 5-ala, b) uno o mas trigliceridos y c) uno o mas emulsionadores. | |
| ECSP14014544A (es) | Compuestos terapéuticamente activos y sus métodos de uso | |
| BR112015019432A2 (pt) | Compostos de tubulisina, métodos de produção e uso | |
| MX388787B (es) | El uso de amisulpride como un anti-emético. | |
| CO7240372A2 (es) | Formulaciones farmacéuticas tópicas no acuosas | |
| CO6290654A2 (es) | Derivados de salinosporamida como inhibidores de proteasoma | |
| CU24349B1 (es) | Composiciones que comprenden 2,3-dihidroimidazo [1,2-c] quinazolinas sustituidas útiles para el tratamiento del cáncer | |
| HN2006009000A (es) | Formas farmaceuticas con propiedades farmacocineticas mejoradas | |
| UY33417A (es) | Formulación que contiene acido azelaico con adición de pigmento | |
| BR112013000613A2 (pt) | composições secas e dispositivos que contêm tais composições secas | |
| MY162934A (en) | Anticancer steroidal lactones unsaturated in position 7 (8) | |
| ES2673406T3 (es) | Alfa-derivados de ácidos grasos cis-monoinsaturados para uso como medicamentos en el tratamiento de la diabetes | |
| ES2659519T3 (es) | Método para producir medicamentos para combatir tumores | |
| CL2012003265A1 (es) | Polisacarido de semillas de tamarindo para usarse en el tratamiento de enfermedades infecciosas; composicion farmacéutica y/o dermocosmética antiinflamatoria que contiene dicho polisacárido; uso de un polisacárido de semilla de tamarindo. | |
| ECSP10010464A (es) | Uso de ranolazina para el tratamiento de enfermedades cardiovasculares | |
| ES2525833T3 (es) | Supresión del crecimiento del cáncer y la metástasis mediante el uso de derivados de ácido nordihidroguayarético con 7-hidroxiestaurosporina | |
| CL2017000971A1 (es) | Composición farmacéutica para uso en el aumento del trofismo de mucosa nasal | |
| CL2008001477A1 (es) | Composicion farmaceutica compuesta por la combinacion sinergica de un agente anticonvulsivante como gabapentina y un agente antiinflamatorio no esteroideo como meloxicam, los rangos de concentracion presentes para la gabapentina son 3 a 300 mg y de 0,1 a 30 mg para meloxicam; y uso para tratar el dolor neuropatico | |
| ES2578729T3 (es) | Agente terapéutico para enfermedades relacionadas con el hígado |