JP2012524524A5 - - Google Patents

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Publication number
JP2012524524A5
JP2012524524A5 JP2012502617A JP2012502617A JP2012524524A5 JP 2012524524 A5 JP2012524524 A5 JP 2012524524A5 JP 2012502617 A JP2012502617 A JP 2012502617A JP 2012502617 A JP2012502617 A JP 2012502617A JP 2012524524 A5 JP2012524524 A5 JP 2012524524A5
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JP
Japan
Prior art keywords
antibody
seq
binding protein
amino acid
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2012502617A
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English (en)
Japanese (ja)
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JP2012524524A (ja
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Publication date
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Priority claimed from PCT/EP2010/054093 external-priority patent/WO2010112458A1/en
Publication of JP2012524524A publication Critical patent/JP2012524524A/ja
Publication of JP2012524524A5 publication Critical patent/JP2012524524A5/ja
Ceased legal-status Critical Current

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JP2012502617A 2009-04-27 2010-03-29 IL−12レセプターβ1サブユニットに特異的な治療用抗体の組成物および使用方法 Ceased JP2012524524A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16517709P 2009-04-27 2009-04-27
US61/165,177 2009-04-27
PCT/EP2010/054093 WO2010112458A1 (en) 2009-03-31 2010-03-29 Composition and methods of use for therapeutic antibodies specific for the il-12 receptore betal subunit

Publications (2)

Publication Number Publication Date
JP2012524524A JP2012524524A (ja) 2012-10-18
JP2012524524A5 true JP2012524524A5 (https=) 2013-04-18

Family

ID=42174564

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012502617A Ceased JP2012524524A (ja) 2009-04-27 2010-03-29 IL−12レセプターβ1サブユニットに特異的な治療用抗体の組成物および使用方法

Country Status (11)

Country Link
US (2) US8715657B2 (https=)
EP (1) EP2424894A1 (https=)
JP (1) JP2012524524A (https=)
KR (1) KR20120057563A (https=)
CN (1) CN102414223A (https=)
AU (1) AU2010230311B9 (https=)
BR (1) BRPI1016055A2 (https=)
CA (1) CA2759942A1 (https=)
EA (1) EA201101572A1 (https=)
MX (1) MX2011011338A (https=)
WO (1) WO2010112458A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012524524A (ja) * 2009-04-27 2012-10-18 ノバルティス アーゲー IL−12レセプターβ1サブユニットに特異的な治療用抗体の組成物および使用方法
JP2013520426A (ja) 2010-02-18 2013-06-06 ブリストル−マイヤーズ スクイブ カンパニー Il−23に結合する、フィブロネクチンをベースとする足場ドメインタンパク質
EP2625203A1 (en) 2010-10-05 2013-08-14 Novartis AG Anti-il12rbeta1 antibodies and their use in treating autoimmune and inflammatory disorders
CN103275222B (zh) * 2013-05-15 2014-04-16 中山康方生物医药有限公司 一种阻断白介素12 p40功能的单克隆抗体及其编码基因和应用
WO2016102641A1 (en) * 2014-12-24 2016-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of acute exacerbations of chronic obstructive pulmonary disease
KR101873499B1 (ko) * 2015-02-10 2018-07-03 주식회사 원메디칼 혈관 질환 진단용 바이오 마커 및 이의 용도
CN109810947B (zh) * 2019-01-18 2021-06-11 北京贝来生物科技有限公司 一种抑制Th17细胞活化的间充质干细胞及其制备方法和应用
CN118355027A (zh) 2021-10-28 2024-07-16 艾伯维公司 抗淀粉样蛋白β抗体及其使用方法
WO2024040194A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering
CN121219320A (zh) * 2023-05-19 2025-12-26 达科纳治疗有限公司 针对il12受体的双特异性激动性抗体
CN117534732B (zh) * 2023-11-03 2024-10-22 湖南中晟全肽生物科技股份有限公司 一种抑制il-12与其受体结合的多肽及其应用
CN117903313B (zh) * 2023-12-27 2024-09-03 浙江大学 一种抗iars抗体及其应用
CN117986360B (zh) * 2024-02-01 2024-08-27 生物岛实验室 Il18蛋白的特异性抗体及其制备方法与应用

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