JP2012520085A5 - - Google Patents

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Publication number
JP2012520085A5
JP2012520085A5 JP2011554275A JP2011554275A JP2012520085A5 JP 2012520085 A5 JP2012520085 A5 JP 2012520085A5 JP 2011554275 A JP2011554275 A JP 2011554275A JP 2011554275 A JP2011554275 A JP 2011554275A JP 2012520085 A5 JP2012520085 A5 JP 2012520085A5
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JP
Japan
Prior art keywords
sequence
polynucleotide
expression vector
cell
promoter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011554275A
Other languages
English (en)
Japanese (ja)
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JP2012520085A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/027365 external-priority patent/WO2010105277A1/en
Publication of JP2012520085A publication Critical patent/JP2012520085A/ja
Publication of JP2012520085A5 publication Critical patent/JP2012520085A5/ja
Pending legal-status Critical Current

Links

JP2011554275A 2009-03-13 2010-03-15 生物活性rnaの送達のための組成物及び方法 Pending JP2012520085A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16028709P 2009-03-13 2009-03-13
US16028809P 2009-03-13 2009-03-13
US61/160,287 2009-03-13
US61/160,288 2009-03-13
PCT/US2010/027365 WO2010105277A1 (en) 2009-03-13 2010-03-15 Compositions and methods for the delivery of biologically active rnas

Publications (2)

Publication Number Publication Date
JP2012520085A JP2012520085A (ja) 2012-09-06
JP2012520085A5 true JP2012520085A5 (https=) 2013-02-21

Family

ID=42728852

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011554275A Pending JP2012520085A (ja) 2009-03-13 2010-03-15 生物活性rnaの送達のための組成物及び方法

Country Status (8)

Country Link
US (2) US8569065B2 (https=)
EP (1) EP2406379A4 (https=)
JP (1) JP2012520085A (https=)
KR (1) KR20110128345A (https=)
CN (1) CN102625842A (https=)
AU (1) AU2010223888A1 (https=)
CA (1) CA2755245A1 (https=)
WO (1) WO2010105277A1 (https=)

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US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
WO2013151665A2 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins associated with human disease
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
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BR112016009465A8 (pt) 2013-10-28 2018-01-30 Univ Pittsburgh Commonwealth Sys Higher Education vetor de hsv oncolítico.
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US11639371B2 (en) * 2016-02-17 2023-05-02 The Chinese University Of Hong Kong Peptidylic inhibitors of nucleolin (NCL) targeting CAG-repeat RNA toxicity and methods for reducing polyQ-mediated toxicity in polyQ diseases
CN109414414A (zh) 2016-03-16 2019-03-01 戴维·格拉德斯通研究所 用于治疗肥胖症和/或糖尿病以及用于鉴定候选治疗剂的方法和组合物
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