JP2020523983A5 - - Google Patents

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Publication number
JP2020523983A5
JP2020523983A5 JP2019561875A JP2019561875A JP2020523983A5 JP 2020523983 A5 JP2020523983 A5 JP 2020523983A5 JP 2019561875 A JP2019561875 A JP 2019561875A JP 2019561875 A JP2019561875 A JP 2019561875A JP 2020523983 A5 JP2020523983 A5 JP 2020523983A5
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JP
Japan
Prior art keywords
host cell
nucleic acid
arc
arc capsid
capsid
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JP2019561875A
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English (en)
Japanese (ja)
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JP7355382B2 (ja
JP2020523983A (ja
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Priority claimed from PCT/US2018/032105 external-priority patent/WO2018209113A1/en
Publication of JP2020523983A publication Critical patent/JP2020523983A/ja
Publication of JP2020523983A5 publication Critical patent/JP2020523983A5/ja
Priority to JP2023076834A priority Critical patent/JP7774319B2/ja
Application granted granted Critical
Publication of JP7355382B2 publication Critical patent/JP7355382B2/ja
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JP2019561875A 2017-05-10 2018-05-10 Ａｒｃカプシドの組成物及び使用方法 Active JP7355382B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023076834A JP7774319B2 (ja) 2017-05-10 2023-05-08 Ａｒｃカプシドの組成物及び使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762504370P 2017-05-10 2017-05-10
US62/504,370 2017-05-10
US201762543130P 2017-08-09 2017-08-09
US62/543,130 2017-08-09
PCT/US2018/032105 WO2018209113A1 (en) 2017-05-10 2018-05-10 Compositions and methods of use of arc capsids

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023076834A Division JP7774319B2 (ja) 2017-05-10 2023-05-08 Ａｒｃカプシドの組成物及び使用方法

Publications (3)

Publication Number Publication Date
JP2020523983A JP2020523983A (ja) 2020-08-13
JP2020523983A5 true JP2020523983A5 (https=) 2021-07-26
JP7355382B2 JP7355382B2 (ja) 2023-10-03

Family

ID=64104936

Family Applications (2)

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JP2019561875A Active JP7355382B2 (ja) 2017-05-10 2018-05-10 Ａｒｃカプシドの組成物及び使用方法
JP2023076834A Active JP7774319B2 (ja) 2017-05-10 2023-05-08 Ａｒｃカプシドの組成物及び使用方法

Family Applications After (1)

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JP2023076834A Active JP7774319B2 (ja) 2017-05-10 2023-05-08 Ａｒｃカプシドの組成物及び使用方法

Country Status (7)

Country Link
US (1) US20210189432A1 (https=)
EP (1) EP3621660A4 (https=)
JP (2) JP7355382B2 (https=)
CN (1) CN110997011A (https=)
AU (1) AU2018265395B2 (https=)
CA (1) CA3062614A1 (https=)
WO (1) WO2018209113A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9228207B2 (en) 2013-09-06 2016-01-05 President And Fellows Of Harvard College Switchable gRNAs comprising aptamers
US20210163933A1 (en) * 2017-12-11 2021-06-03 University Of Massachusetts Arc protein extracellular vesicle nucleic acid delivery platform
US12522807B2 (en) 2018-07-09 2026-01-13 The Broad Institute, Inc. RNA programmable epigenetic RNA modifiers and uses thereof
AU2019343045A1 (en) 2018-09-18 2021-05-13 Vnv Newco Inc. ARC-based capsids and uses thereof
US12351837B2 (en) 2019-01-23 2025-07-08 The Broad Institute, Inc. Supernegatively charged proteins and uses thereof
WO2020191233A1 (en) 2019-03-19 2020-09-24 The Broad Institute, Inc. Methods and compositions for editing nucleotide sequences
US12473543B2 (en) 2019-04-17 2025-11-18 The Broad Institute, Inc. Adenine base editors with reduced off-target effects
WO2020252455A1 (en) 2019-06-13 2020-12-17 The General Hospital Corporation Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells
US11129892B1 (en) 2020-05-18 2021-09-28 Vnv Newco Inc. Vaccine compositions comprising endogenous Gag polypeptides
CA3189601A1 (en) 2020-07-24 2022-01-27 The General Hospital Corporation Enhanced virus-like particles and methods of use thereof for delivery to cells
WO2022235723A1 (en) * 2021-05-04 2022-11-10 Cornell University Engineered extracellular vesicles
US20260063641A1 (en) * 2022-08-01 2026-03-05 University Of Utah Research Foundation Compositions and methods for labeling and detecting binding partners
CN118576725B (zh) * 2024-08-02 2025-06-03 中国人民解放军军事科学院军事医学研究院 一种以arc蛋白为载体的纳米颗粒及其制备方法和应用
CN120248078B (zh) * 2025-05-28 2025-11-28 中国人民解放军军事科学院军事医学研究院 一种基于arc蛋白的修饰多肽及其作为核酸递送载体的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204059B1 (en) * 1994-06-30 2001-03-20 University Of Pittsburgh AAV capsid vehicles for molecular transfer
US7638269B2 (en) * 1997-02-07 2009-12-29 The Regents Of The University Of California Viral capsid assembly intermediates and methods of production
WO2009042727A1 (en) * 2007-09-24 2009-04-02 The Johns Hopkins University Immediate early gene arc interacts with endocytic machinery and regulates the trafficking and function of presenilin
CA2714972A1 (en) * 2008-02-08 2009-08-13 University Health Network Use of p27kip1 for the prevention and treatment of heart failure
PL2391638T3 (pl) * 2009-02-02 2018-11-30 Glaxosmithkline Biologicals Sa Sekwencje nukleotydowe i aminokwasowe małpiego adenowirusa, zawierające je wektory i ich zastosowania
GB0911870D0 (en) * 2009-07-08 2009-08-19 Ucl Business Plc Optimised coding sequence and promoter
CA2817418A1 (en) * 2010-11-10 2012-05-18 Laboratorios Del Dr. Esteve, S.A. Highly immunogenic hiv p24 sequences
EP3003391B1 (en) 2013-05-31 2021-09-22 The Regents of The University of California Adeno-associated virus variants and methods of use thereof
US10624849B2 (en) 2015-09-28 2020-04-21 Northwestern University Targeted extracellular vesicles comprising membrane proteins with engineered glycosylation sites

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