JP2012519711A5 - - Google Patents
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- Publication number
- JP2012519711A5 JP2012519711A5 JP2011553153A JP2011553153A JP2012519711A5 JP 2012519711 A5 JP2012519711 A5 JP 2012519711A5 JP 2011553153 A JP2011553153 A JP 2011553153A JP 2011553153 A JP2011553153 A JP 2011553153A JP 2012519711 A5 JP2012519711 A5 JP 2012519711A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- drug conjugate
- antibody drug
- pharmaceutical composition
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15814309P | 2009-03-06 | 2009-03-06 | |
| US61/158,143 | 2009-03-06 | ||
| PCT/US2010/026429 WO2010111018A1 (en) | 2009-03-06 | 2010-03-05 | Antibody drug conjugates (adc) that bind to 24p4c12 proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012519711A JP2012519711A (ja) | 2012-08-30 |
| JP2012519711A5 true JP2012519711A5 (enExample) | 2013-04-18 |
Family
ID=42781369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011553153A Pending JP2012519711A (ja) | 2009-03-06 | 2010-03-05 | ２４ｐ４ｃ１２タンパク質に結合する抗体薬物結合体（ａｄｃ） |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8309093B2 (enExample) |
| EP (1) | EP2403524A4 (enExample) |
| JP (1) | JP2012519711A (enExample) |
| KR (1) | KR20120034591A (enExample) |
| CN (1) | CN102448486A (enExample) |
| AU (1) | AU2010229192A1 (enExample) |
| BR (1) | BRPI1013645A2 (enExample) |
| CA (1) | CA2754531A1 (enExample) |
| IL (1) | IL214983A0 (enExample) |
| MX (1) | MX2011009281A (enExample) |
| RU (1) | RU2011140491A (enExample) |
| SG (1) | SG174259A1 (enExample) |
| TW (1) | TW201043249A (enExample) |
| WO (1) | WO2010111018A1 (enExample) |
| ZA (1) | ZA201107293B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2403524A4 (en) * | 2009-03-06 | 2012-09-26 | Agensys Inc | CONJUGATES ANTIBODY-DRUG (ADC) BINDING PROTEINS 24P4C12 |
| US9402916B2 (en) | 2011-03-17 | 2016-08-02 | The University Of Birmingham | Re-directed immunotherapy |
| KR102179369B1 (ko) * | 2011-05-27 | 2020-11-16 | 암브룩스, 인코포레이티드 | 비-천연 아미노산 연결된 돌라스타틴 유도체를 함유하는 조성물, 이를 수반하는 방법, 및 용도 |
| TR201900694T4 (tr) * | 2012-08-23 | 2019-02-21 | Agensys Inc | 158p1d7 proteinlerine bağlanan antikor ilaç konjugatları (adc). |
| US9353150B2 (en) | 2012-12-04 | 2016-05-31 | Massachusetts Institute Of Technology | Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment |
| AR094280A1 (es) | 2012-12-21 | 2015-07-22 | Bioalliance Cv | Enlazantes hidrofilicos auto-inmolantes y conjugados de los mismos |
| EP2777714A1 (en) | 2013-03-15 | 2014-09-17 | NBE-Therapeutics LLC | Method of producing an immunoligand/payload conjugate by means of a sequence-specific transpeptidase enzyme |
| FR3005051A1 (fr) * | 2013-04-25 | 2014-10-31 | Pf Medicament | Derives de la dolastatine 10 et d'auristatines |
| KR20160111469A (ko) * | 2014-01-24 | 2016-09-26 | 제넨테크, 인크. | 항-steap1 항체 및 면역접합체를 사용하는 방법 |
| TWI731535B (zh) | 2014-03-21 | 2021-06-21 | 美商艾伯維有限公司 | 抗-egfr抗體及抗體藥物結合物 |
| BR112016024619A2 (pt) | 2014-04-25 | 2017-10-10 | Pf Medicament | conjugado de anticorpo ao igf-1r-fármaco e seu uso para o tratamento de câncer |
| HUE047952T2 (hu) | 2014-04-25 | 2020-05-28 | Pf Medicament | Ellenanyag-drog konjugátum és alkalmazása rák kezelésében történõ alkalmazásra |
| WO2015195904A1 (en) * | 2014-06-20 | 2015-12-23 | Abgenomics International Inc. | Her2 antibody-drug conjugates |
| MX2016016490A (es) | 2014-06-20 | 2017-07-28 | Bioalliance Cv | Conjugados de farmaco-anticuerpo anti-receptor de folato alfa (fra) y metodos de uso de los mismos. |
| WO2016001485A1 (en) | 2014-06-30 | 2016-01-07 | Glykos Finland Oy | Saccharide derivative of a toxic payload and antibody conjugates thereof |
| CN107750169B (zh) | 2014-12-23 | 2022-02-08 | 恩比伊治疗股份公司 | 包含蒽环类衍生物的结合蛋白药物缀合物 |
| RU2766000C2 (ru) | 2016-01-08 | 2022-02-07 | АльтруБио Инк. | Четырехвалентные антитела к psgl-1 и их применения |
| WO2017197045A1 (en) | 2016-05-11 | 2017-11-16 | Movassaghi Mohammad | Convergent and enantioselective total synthesis of communesin analogs |
| JP2019526529A (ja) | 2016-06-08 | 2019-09-19 | アッヴィ・インコーポレイテッド | 抗ｂ７−ｈ３抗体及び抗体薬物コンジュゲート |
| CN109641962A (zh) | 2016-06-08 | 2019-04-16 | 艾伯维公司 | 抗b7-h3抗体和抗体药物偶联物 |
| RS61828B1 (sr) | 2016-06-08 | 2021-06-30 | Abbvie Inc | Anti-b7-h3 antitela i antitelske konjugacije lekova |
| AU2017277914A1 (en) | 2016-06-08 | 2019-01-03 | Abbvie Inc. | Anti-CD98 antibodies and antibody drug conjugates |
| BR112018075644A2 (pt) | 2016-06-08 | 2019-04-09 | Abbvie Inc. | anticorpos anti-cd98 e conjugados de anticorpo e fármaco |
| WO2018209239A1 (en) | 2017-05-11 | 2018-11-15 | Massachusetts Institute Of Technology | Potent agelastatin derivatives as modulators for cancer invasion and metastasis |
| EP3925976A1 (en) | 2017-09-07 | 2021-12-22 | Dragonfly Therapeutics, Inc. | Proteins binding nkg2d, cd16 and a tumor-associated antigen |
| US10640508B2 (en) | 2017-10-13 | 2020-05-05 | Massachusetts Institute Of Technology | Diazene directed modular synthesis of compounds with quaternary carbon centers |
| CA3120800A1 (en) | 2018-12-17 | 2020-06-25 | Revitope Limited | Twin immune cell engager |
| WO2020247054A1 (en) | 2019-06-05 | 2020-12-10 | Massachusetts Institute Of Technology | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof |
| AR124681A1 (es) | 2021-01-20 | 2023-04-26 | Abbvie Inc | Conjugados anticuerpo-fármaco anti-egfr |
| WO2022182415A1 (en) | 2021-02-24 | 2022-09-01 | Massachusetts Institute Of Technology | Himastatin derivatives, and processes of preparation thereof, and uses thereof |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4742000A (en) | 1986-05-02 | 1988-05-03 | University Of Chicago | Antibody to human progesterone receptor and diagnostic materials and methods |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6130237A (en) | 1996-09-12 | 2000-10-10 | Cancer Research Campaign Technology Limited | Condensed N-aclyindoles as antitumor agents |
| US20030082546A1 (en) | 1996-11-06 | 2003-05-01 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6800746B2 (en) | 1997-02-25 | 2004-10-05 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| US6930170B2 (en) | 1997-06-16 | 2005-08-16 | Genentech, Inc. | PRO1184 polypeptides |
| US7109318B2 (en) | 1997-06-16 | 2006-09-19 | Genentech, Inc. | Nucleic acids encoding PRO830 |
| US7393663B2 (en) | 1997-08-01 | 2008-07-01 | Serono Genetics Institute S.A. | Expressed sequence tags and encoded human proteins |
| US7160985B2 (en) | 1997-10-29 | 2007-01-09 | Genentech, Inc. | Pro180 polypeptide |
| AU764441B2 (en) | 1998-02-09 | 2003-08-21 | Genset S.A. | cDNAs encoding secreted proteins |
| US6747137B1 (en) | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| US6551795B1 (en) | 1998-02-18 | 2003-04-22 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics |
| US20030050465A1 (en) | 1998-08-10 | 2003-03-13 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7109003B2 (en) | 1998-12-23 | 2006-09-19 | Abgenix, Inc. | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 |
| EE05627B1 (et) | 1998-12-23 | 2013-02-15 | Pfizer Inc. | CTLA-4 vastased inimese monoklonaalsed antikehad |
| US20030009013A1 (en) | 1998-12-30 | 2003-01-09 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2296792A1 (en) | 1999-02-26 | 2000-08-26 | Genset S.A. | Expressed sequence tags and encoded human proteins |
| EP1171595A1 (en) | 1999-04-12 | 2002-01-16 | Agensys, Inc. | 13 transmembrane protein expressed in prostate cancer |
| US7244827B2 (en) | 2000-04-12 | 2007-07-17 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer |
| US6943235B1 (en) * | 1999-04-12 | 2005-09-13 | Agensys, Inc. | Transmembrane protein expressed in prostate cancer |
| EP1074617A3 (en) | 1999-07-29 | 2004-04-21 | Research Association for Biotechnology | Primers for synthesising full-length cDNA and their use |
| FR2800750B1 (fr) | 1999-11-05 | 2003-01-31 | Centre Nat Rech Scient | Proteines membranaires ctl (choline transporter like) impliquees dans le transport de la choline |
| US20020192763A1 (en) | 2000-04-17 | 2002-12-19 | Jiangchun Xu | Compositions and methods for the therapy and diagnosis of prostate cancer |
| US20030099974A1 (en) | 2001-07-18 | 2003-05-29 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits and methods for identification, assessment, prevention, and therapy of breast cancer |
| US20030073623A1 (en) | 2001-07-30 | 2003-04-17 | Drmanac Radoje T. | Novel nucleic acid sequences obtained from various cDNA libraries |
| AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| US20030023042A1 (en) | 2001-12-06 | 2003-01-30 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7378492B2 (en) | 2002-02-20 | 2008-05-27 | Incyte Corporation | CD40-related receptor that binds CD40L |
| DK1545613T3 (da) | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| JP2006508163A (ja) * | 2002-11-27 | 2006-03-09 | アジェンシス， インコーポレイテッド | 癌の処置および検出において有用な２４ｐ４ｃ１２と称される、核酸および対応タンパク質 |
| CN107213469A (zh) | 2003-11-06 | 2017-09-29 | 西雅图基因公司 | 能够与配体偶联的单甲基缬氨酸化合物 |
| AU2005271523B2 (en) * | 2004-08-03 | 2011-09-15 | Dyax Corp. | hk1-binding proteins |
| BRPI0612529A2 (pt) * | 2005-06-20 | 2010-11-23 | Psma Dev Company Llc | conjugados de anticorpo-medicamento de psma |
| WO2007114979A2 (en) | 2006-02-17 | 2007-10-11 | Genentech, Inc. | Gene disruptons, compositions and methods relating thereto |
| ES2424745T3 (es) * | 2007-09-07 | 2013-10-08 | Agensys, Inc. | Anticuerpos y moléculas relacionadas que se unen a las proteínas 24P4C12 |
| US8039597B2 (en) | 2007-09-07 | 2011-10-18 | Agensys, Inc. | Antibodies and related molecules that bind to 24P4C12 proteins |
| EP2403524A4 (en) * | 2009-03-06 | 2012-09-26 | Agensys Inc | CONJUGATES ANTIBODY-DRUG (ADC) BINDING PROTEINS 24P4C12 |
-
2010
- 2010-03-05 EP EP10756560A patent/EP2403524A4/en not_active Withdrawn
- 2010-03-05 AU AU2010229192A patent/AU2010229192A1/en not_active Abandoned
- 2010-03-05 BR BRPI1013645A patent/BRPI1013645A2/pt not_active IP Right Cessation
- 2010-03-05 MX MX2011009281A patent/MX2011009281A/es unknown
- 2010-03-05 US US12/718,902 patent/US8309093B2/en active Active
- 2010-03-05 JP JP2011553153A patent/JP2012519711A/ja active Pending
- 2010-03-05 CN CN2010800203364A patent/CN102448486A/zh active Pending
- 2010-03-05 CA CA2754531A patent/CA2754531A1/en not_active Abandoned
- 2010-03-05 WO PCT/US2010/026429 patent/WO2010111018A1/en not_active Ceased
- 2010-03-05 KR KR1020117023550A patent/KR20120034591A/ko not_active Withdrawn
- 2010-03-05 SG SG2011063930A patent/SG174259A1/en unknown
- 2010-03-05 RU RU2011140491/10A patent/RU2011140491A/ru not_active Application Discontinuation
- 2010-03-08 TW TW099106660A patent/TW201043249A/zh unknown
-
2011
- 2011-09-05 IL IL214983A patent/IL214983A0/en unknown
- 2011-10-05 ZA ZA2011/07293A patent/ZA201107293B/en unknown
-
2012
- 2012-11-08 US US13/672,419 patent/US20130136756A1/en not_active Abandoned
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