JP2010537671A5 - - Google Patents
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- Publication number
- JP2010537671A5 JP2010537671A5 JP2010524202A JP2010524202A JP2010537671A5 JP 2010537671 A5 JP2010537671 A5 JP 2010537671A5 JP 2010524202 A JP2010524202 A JP 2010524202A JP 2010524202 A JP2010524202 A JP 2010524202A JP 2010537671 A5 JP2010537671 A5 JP 2010537671A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- fragment
- monoclonal antibody
- seq
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19003407P | 2007-09-07 | 2007-09-07 | |
| US2007077942 | 2007-09-07 | ||
| USPCT/US2007/077942 | 2007-09-07 | ||
| US61/190,034 | 2007-09-07 | ||
| PCT/US2008/075488 WO2009033094A2 (en) | 2007-09-07 | 2008-09-05 | Antibodies and related molecules that bind to 24p4c12 proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010537671A JP2010537671A (ja) | 2010-12-09 |
| JP2010537671A5 true JP2010537671A5 (enExample) | 2011-06-16 |
| JP5518711B2 JP5518711B2 (ja) | 2014-06-11 |
Family
ID=40429722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524202A Active JP5518711B2 (ja) | 2007-09-07 | 2008-09-05 | ２４ｐ４ｃ１２タンパク質に結合する抗体および関連分子 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP2185574B1 (enExample) |
| JP (1) | JP5518711B2 (enExample) |
| CA (1) | CA2698287A1 (enExample) |
| DK (1) | DK2185574T3 (enExample) |
| ES (1) | ES2424745T3 (enExample) |
| HR (1) | HRP20130649T1 (enExample) |
| PL (1) | PL2185574T3 (enExample) |
| PT (1) | PT2185574E (enExample) |
| WO (1) | WO2009033094A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7244827B2 (en) * | 2000-04-12 | 2007-07-17 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer |
| WO2010022279A1 (en) * | 2008-08-20 | 2010-02-25 | Agensys, Inc. | Antibodies and related molecules that bind to 58p1d12 proteins |
| US8309093B2 (en) * | 2009-03-06 | 2012-11-13 | Agensys, Inc. | Antibody drug conjugates (ADC) that bind to 24P4C12 proteins |
| BR112013027119A8 (pt) | 2011-04-21 | 2018-03-06 | Seattle Genetics Inc | novos conjugados ligante-droga (adcs) e uso dos mesmos |
| RU2698697C2 (ru) | 2013-12-23 | 2019-08-29 | Байер Фарма Акциенгезельшафт | Конъюгаты связующего (ADC) с ингибиторами KSP |
| KR102763121B1 (ko) | 2015-02-06 | 2025-02-04 | 내셔널 유니버시티 오브 싱가포르 | 치료적 면역 세포의 효능의 향상 방법 |
| JP6971858B2 (ja) | 2015-06-22 | 2021-11-24 | バイエル ファーマ アクチエンゲゼルシャフト | 酵素開裂性基を有する抗体薬物複合体（ａｄｃ）および抗体プロドラッグ複合体（ａｐｄｃ） |
| WO2017060322A2 (en) | 2015-10-10 | 2017-04-13 | Bayer Pharma Aktiengesellschaft | Ptefb-inhibitor-adc |
| JP7251981B2 (ja) | 2016-03-24 | 2023-04-04 | バイエル ファーマ アクチエンゲゼルシャフト | 酵素開裂基を有する細胞毒性活性剤のプロドラッグ |
| EP3919518A1 (en) | 2016-06-15 | 2021-12-08 | Bayer Pharma Aktiengesellschaft | Specific antibody-drug-conjugates (adcs) with ksp inhibitors and anti-cd123-antibodies |
| CN107841502A (zh) * | 2016-09-17 | 2018-03-27 | 复旦大学 | 核酸分子ctl4hsh1、其制备方法及应用 |
| CN107841501A (zh) * | 2016-09-18 | 2018-03-27 | 复旦大学 | 核酸分子ctl4hsh20、其制备方法及应用 |
| CN107841500A (zh) * | 2016-09-18 | 2018-03-27 | 复旦大学 | 核酸分子ctl4hsh18、其制备方法及应用 |
| CN107868783A (zh) * | 2016-09-26 | 2018-04-03 | 复旦大学 | 核酸分子ctl4hsh2、其制备方法及应用 |
| CN107868782A (zh) * | 2016-09-26 | 2018-04-03 | 复旦大学 | 核酸分子ctl4hsh3、其制备方法及应用 |
| CN107881171A (zh) * | 2016-09-30 | 2018-04-06 | 复旦大学 | 核酸分子ctl4hsh12、其制备方法及应用 |
| CN108070588A (zh) * | 2016-11-08 | 2018-05-25 | 复旦大学 | 核酸分子ctl4hsh8、其制备方法及应用 |
| NZ752984A (en) | 2016-11-22 | 2026-03-27 | Nat Univ Singapore | Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies |
| CN108118052A (zh) * | 2016-11-29 | 2018-06-05 | 复旦大学 | 核酸分子ctl4hsh17、其制备方法及应用 |
| US12059472B2 (en) | 2016-12-21 | 2024-08-13 | Bayer Aktiengesellschaft | Prodrugs of cytotoxic active agents having enzymatically cleavable groups |
| CN110312534B (zh) | 2016-12-21 | 2023-04-04 | 拜耳制药股份公司 | 具有酶促可裂解基团的抗体-药物-缀合物(adc) |
| CN110072556B (zh) | 2016-12-21 | 2023-05-02 | 拜耳制药股份公司 | 具有ksp抑制剂的特异性抗体药物缀合物(adc) |
| CN108330128A (zh) * | 2017-01-17 | 2018-07-27 | 复旦大学 | 核酸分子ctl4hsh10、其制备方法及应用 |
| US20190038733A1 (en) | 2017-08-10 | 2019-02-07 | National University Of Singapore | T cell receptor-deficient chimeric antigen receptor t-cells and methods of use thereof |
| EP3553081A1 (en) | 2018-04-12 | 2019-10-16 | Bayer Aktiengesellschaft | Atrial natriuretic peptide engrafted antibodies |
| EP3553079A1 (en) * | 2018-04-12 | 2019-10-16 | Bayer Aktiengesellschaft | C-type natriuretic peptide engrafted antibodies |
| EP3553082A1 (en) | 2018-04-12 | 2019-10-16 | Bayer Aktiengesellschaft | Brain natriuretic peptide engrafted antibodies |
| EP3784776A4 (en) | 2018-05-23 | 2022-01-26 | National University of Singapore | Blockade of cd2 surface expression and expression of chimeric antigen receptors for immunotherapy of t-cell malignancies |
| WO2024192280A2 (en) * | 2023-03-14 | 2024-09-19 | Mapp Biopharmaceutical, Inc. | Antibodies against orthohantaviruses |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI941572A7 (fi) | 1991-10-07 | 1994-05-27 | Oncologix Inc | Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä |
| CA2372813A1 (en) | 1992-02-06 | 1993-08-19 | L.L. Houston | Biosynthetic binding protein for cancer marker |
| WO1994026877A1 (en) | 1993-05-17 | 1994-11-24 | The Regents Of The University Of California | Ribozyme gene therapy for hiv infection and aids |
| IL112248A0 (en) | 1994-01-25 | 1995-03-30 | Warner Lambert Co | Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them |
| US5747498A (en) | 1996-05-28 | 1998-05-05 | Pfizer Inc. | Alkynyl and azido-substituted 4-anilinoquinazolines |
| GB9520822D0 (en) | 1995-10-11 | 1995-12-13 | Wellcome Found | Therapeutically active compounds |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| EA199900021A1 (ru) | 1996-07-13 | 1999-08-26 | Глаксо, Груп Лимитед | Бициклические гетероароматические соединения в качестве ингибиторов протеинтирозинкиназы |
| AR007857A1 (es) | 1996-07-13 | 1999-11-24 | Glaxo Group Ltd | Compuestos heterociclicos fusionados como inhibidores de proteina tirosina quinasa, sus metodos de preparacion, intermediarios uso en medicina ycomposiciones farmaceuticas que los contienen. |
| HRP970371A2 (en) | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
| ID18494A (id) | 1996-10-02 | 1998-04-16 | Novartis Ag | Turunan pirazola leburan dan proses pembuatannya |
| JP2002501532A (ja) | 1997-05-30 | 2002-01-15 | メルク エンド カンパニー インコーポレーテッド | 新規血管形成阻害薬 |
| AU744939B2 (en) | 1997-09-26 | 2002-03-07 | Merck & Co., Inc. | Novel angiogenesis inhibitors |
| RS49779B (sr) | 1998-01-12 | 2008-06-05 | Glaxo Group Limited, | Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze |
| GB9800575D0 (en) | 1998-01-12 | 1998-03-11 | Glaxo Group Ltd | Heterocyclic compounds |
| US7109003B2 (en) * | 1998-12-23 | 2006-09-19 | Abgenix, Inc. | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 |
| UA71945C2 (en) | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
| JP3270834B2 (ja) | 1999-01-27 | 2002-04-02 | ファイザー・プロダクツ・インク | 抗がん剤として有用なヘテロ芳香族二環式誘導体 |
| US6943235B1 (en) * | 1999-04-12 | 2005-09-13 | Agensys, Inc. | Transmembrane protein expressed in prostate cancer |
| WO2000061746A1 (en) * | 1999-04-12 | 2000-10-19 | Agensys, Inc. | 13 transmembrane protein expressed in prostate cancer |
| EP1565200A4 (en) * | 2002-11-27 | 2009-06-24 | Agensys Inc | NUCLEIC ACID 24P4C12 AND CORRESPONDING PROTEIN FOR THE TREATMENT AND DETECTION OF CANCER |
-
2008
- 2008-09-05 PT PT87992681T patent/PT2185574E/pt unknown
- 2008-09-05 WO PCT/US2008/075488 patent/WO2009033094A2/en not_active Ceased
- 2008-09-05 EP EP08799268.1A patent/EP2185574B1/en active Active
- 2008-09-05 ES ES08799268T patent/ES2424745T3/es active Active
- 2008-09-05 HR HRP20130649AT patent/HRP20130649T1/hr unknown
- 2008-09-05 CA CA2698287A patent/CA2698287A1/en not_active Abandoned
- 2008-09-05 PL PL08799268T patent/PL2185574T3/pl unknown
- 2008-09-05 JP JP2010524202A patent/JP5518711B2/ja active Active
- 2008-09-05 DK DK08799268.1T patent/DK2185574T3/da active
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