JP2010523469A5 - - Google Patents
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- Publication number
- JP2010523469A5 JP2010523469A5 JP2009534901A JP2009534901A JP2010523469A5 JP 2010523469 A5 JP2010523469 A5 JP 2010523469A5 JP 2009534901 A JP2009534901 A JP 2009534901A JP 2009534901 A JP2009534901 A JP 2009534901A JP 2010523469 A5 JP2010523469 A5 JP 2010523469A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- amino acid
- immunoconjugate
- seq
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 CC[C@](C)[C@](CN(C)C([C@@](*C([C@](C(C)C)N(C)C)=O)C(C)C)=O)[C@@](CC(N(CCC1)[C@@]1[C@@](C(C(NC([C@](c1ccccc1)O)=C)=O)=C)OC)=O)OC Chemical compound CC[C@](C)[C@](CN(C)C([C@@](*C([C@](C(C)C)N(C)C)=O)C(C)C)=O)[C@@](CC(N(CCC1)[C@@]1[C@@](C(C(NC([C@](c1ccccc1)O)=C)=O)=C)OC)=O)OC 0.000 description 3
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92130007P | 2007-03-30 | 2007-03-30 | |
| US60/921,300 | 2007-03-30 | ||
| US93785707P | 2007-06-29 | 2007-06-29 | |
| US60/937,857 | 2007-06-29 | ||
| PCT/US2007/082726 WO2008052187A2 (en) | 2006-10-27 | 2007-10-26 | Antibodies and immunoconjugates and uses therefor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013217609A Division JP5837019B2 (ja) | 2007-03-30 | 2013-10-18 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010523469A JP2010523469A (ja) | 2010-07-15 |
| JP2010523469A5 true JP2010523469A5 (enExample) | 2010-12-16 |
| JP5394246B2 JP5394246B2 (ja) | 2014-01-22 |
Family
ID=42575819
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534901A Active JP5394246B2 (ja) | 2007-03-30 | 2007-10-26 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
| JP2013217609A Active JP5837019B2 (ja) | 2007-03-30 | 2013-10-18 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
| JP2015217734A Active JP6185540B2 (ja) | 2007-03-30 | 2015-11-05 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013217609A Active JP5837019B2 (ja) | 2007-03-30 | 2013-10-18 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
| JP2015217734A Active JP6185540B2 (ja) | 2007-03-30 | 2015-11-05 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (3) | JP5394246B2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5990947A (ja) * | 1982-11-16 | 1984-05-25 | Matsushita Electronics Corp | 半導体装置 |
| ES2553874T3 (es) * | 2010-09-29 | 2015-12-14 | Seattle Genetics, Inc. | N-Carboxialquil-auristatinas y su uso |
| EP2621526B1 (en) * | 2010-09-29 | 2018-06-06 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
| TW201300417A (zh) * | 2010-11-10 | 2013-01-01 | Genentech Inc | 用於神經疾病免疫療法之方法及組合物 |
| SG10201605401WA (en) * | 2011-04-01 | 2016-08-30 | Wyeth Llc | Antibody-drug conjugates |
| TWI589592B (zh) * | 2011-11-17 | 2017-07-01 | 輝瑞股份有限公司 | 胞毒性肽類以及其抗體藥物共軛體 |
| MX350807B (es) * | 2011-11-29 | 2017-09-20 | Genentech Inc | Composiciones y metodos para el analisis de cancer de prostata. |
| CA2869704A1 (en) * | 2012-04-04 | 2013-10-10 | Perseus Proteomics Inc. | Drug conjugate comprising anti-cdh3 (pcadherin) antibody |
| CN103566377A (zh) * | 2012-07-18 | 2014-02-12 | 上海博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| EP3964237B1 (en) * | 2013-03-15 | 2026-02-18 | Regeneron Pharmaceuticals, Inc. | Biologically active molecules, conjugates thereof, and therapeutic uses |
| EP3092255A4 (en) * | 2014-01-10 | 2017-09-20 | Birdie Biopharmaceuticals Inc. | Compounds and compositions for treating egfr expressing tumors |
| CN106413756A (zh) * | 2014-01-24 | 2017-02-15 | 豪夫迈·罗氏有限公司 | 使用抗steap1抗体和免疫缀合物的方法 |
| TW202214691A (zh) * | 2014-03-21 | 2022-04-16 | 美商艾伯維有限公司 | 抗-egfr抗體及抗體藥物結合物 |
| KR102463267B1 (ko) * | 2014-07-24 | 2022-11-03 | 제넨테크, 인크. | 적어도 하나의 트리설파이드 결합을 함유하는 단백질에서 티올 모이어티에 제제의 접합 방법 |
| JP2018533930A (ja) * | 2015-10-02 | 2018-11-22 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 二重特異性ｔ細胞活性化抗原結合分子 |
| MY208638A (en) * | 2018-07-02 | 2025-05-21 | Amgen Inc | Anti-steap1 antigen-binding protein |
| US12257340B2 (en) | 2018-12-03 | 2025-03-25 | Agensys, Inc. | Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof |
| CA3166732A1 (en) * | 2020-01-22 | 2021-07-29 | Medimmune Limited | Compounds and conjugates thereof |
| CN111494645B (zh) * | 2020-05-20 | 2022-09-30 | 中国药科大学 | 抗人dll4人源化抗体与美登素生物碱dm1的偶联物及其制备方法与应用 |
| JP2024519982A (ja) * | 2021-05-24 | 2024-05-21 | レメゲン シーオー．，エルティーディー． | Ｈｅｒ２低発現乳癌の治療における、ｈｅｒ２標的抗体薬物コンジュゲートの使用 |
| JP7451677B2 (ja) * | 2021-07-19 | 2024-03-18 | 煙台邁百瑞国際生物医薬股▲ふん▼有限公司 | 二成分毒素を担った抗体薬物複合体及びその応用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1244705B1 (en) * | 1999-12-06 | 2010-01-27 | Agensys, Inc. | Serpentine transmembrane antigens expressed in human prostate cancers and uses thereof |
| NZ550816A (en) * | 2004-04-22 | 2009-12-24 | Agensys Inc | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| ES2579805T3 (es) * | 2004-09-23 | 2016-08-16 | Genentech, Inc. | Anticuerpos y conjugados modificados por ingeniería genética con cisteína |
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2007
- 2007-10-26 JP JP2009534901A patent/JP5394246B2/ja active Active
-
2013
- 2013-10-18 JP JP2013217609A patent/JP5837019B2/ja active Active
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2015
- 2015-11-05 JP JP2015217734A patent/JP6185540B2/ja active Active