JP2010523469A5 - - Google Patents
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- Publication number
- JP2010523469A5 JP2010523469A5 JP2009534901A JP2009534901A JP2010523469A5 JP 2010523469 A5 JP2010523469 A5 JP 2010523469A5 JP 2009534901 A JP2009534901 A JP 2009534901A JP 2009534901 A JP2009534901 A JP 2009534901A JP 2010523469 A5 JP2010523469 A5 JP 2010523469A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- amino acid
- immunoconjugate
- seq
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 CC[C@](C)[C@](CN(C)C([C@@](*C([C@](C(C)C)N(C)C)=O)C(C)C)=O)[C@@](CC(N(CCC1)[C@@]1[C@@](C(C(NC([C@](c1ccccc1)O)=C)=O)=C)OC)=O)OC Chemical compound CC[C@](C)[C@](CN(C)C([C@@](*C([C@](C(C)C)N(C)C)=O)C(C)C)=O)[C@@](CC(N(CCC1)[C@@]1[C@@](C(C(NC([C@](c1ccccc1)O)=C)=O)=C)OC)=O)OC 0.000 description 3
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92130007P | 2007-03-30 | 2007-03-30 | |
| US60/921,300 | 2007-03-30 | ||
| US93785707P | 2007-06-29 | 2007-06-29 | |
| US60/937,857 | 2007-06-29 | ||
| PCT/US2007/082726 WO2008052187A2 (en) | 2006-10-27 | 2007-10-26 | Antibodies and immunoconjugates and uses therefor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013217609A Division JP5837019B2 (ja) | 2007-03-30 | 2013-10-18 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010523469A JP2010523469A (ja) | 2010-07-15 |
| JP2010523469A5 true JP2010523469A5 (enExample) | 2010-12-16 |
| JP5394246B2 JP5394246B2 (ja) | 2014-01-22 |
Family
ID=42575819
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534901A Active JP5394246B2 (ja) | 2007-03-30 | 2007-10-26 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
| JP2013217609A Active JP5837019B2 (ja) | 2007-03-30 | 2013-10-18 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
| JP2015217734A Active JP6185540B2 (ja) | 2007-03-30 | 2015-11-05 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013217609A Active JP5837019B2 (ja) | 2007-03-30 | 2013-10-18 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
| JP2015217734A Active JP6185540B2 (ja) | 2007-03-30 | 2015-11-05 | 抗体及びイムノコンジュゲートとこれらの使用方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (3) | JP5394246B2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5990947A (ja) * | 1982-11-16 | 1984-05-25 | Matsushita Electronics Corp | 半導体装置 |
| MX347954B (es) * | 2010-09-29 | 2017-05-19 | Agensys Inc | Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. |
| JP5933562B2 (ja) * | 2010-09-29 | 2016-06-15 | シアトル ジェネティックス， インコーポレイテッド | Ｎ−カルボキシアルキル−アウリスタチンおよびその使用 |
| WO2012064836A1 (en) * | 2010-11-10 | 2012-05-18 | Genentech, Inc. | Methods and compositions for neural disease immunotherapy |
| WO2012131527A1 (en) * | 2011-04-01 | 2012-10-04 | Wyeth Llc | Antibody-drug conjugates |
| CN104185477B (zh) * | 2011-11-17 | 2017-05-24 | 辉瑞公司 | 细胞毒性肽及其抗体‑药物缀合物 |
| MX350807B (es) * | 2011-11-29 | 2017-09-20 | Genentech Inc | Composiciones y metodos para el analisis de cancer de prostata. |
| CA2869704A1 (en) | 2012-04-04 | 2013-10-10 | Perseus Proteomics Inc. | Drug conjugate comprising anti-cdh3 (pcadherin) antibody |
| CN112587671A (zh) * | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| JP6847388B2 (ja) * | 2013-03-15 | 2021-03-31 | レゲネロン ファーマシューティカルス，インコーポレーテッド | 生物活性分子、そのコンジュゲート、及び治療用途 |
| DK3092256T3 (da) * | 2014-01-10 | 2022-06-20 | Birdie Biopharmaceuticals Inc | Forbindelser og sammensætninger til immunterapi |
| EP3096797A1 (en) * | 2014-01-24 | 2016-11-30 | F. Hoffmann-La Roche AG | Methods of using anti-steap1 antibodies and immunoconjugates |
| AR099812A1 (es) * | 2014-03-21 | 2016-08-17 | Abbvie Inc | Anticuerpos y conjugados de anticuerpo y fármaco anti-egfr |
| SG11201700365TA (en) * | 2014-07-24 | 2017-02-27 | Genentech Inc | Methods of conjugating an agent to a thiol moiety in a protein that contains at least one trisulfide bond |
| JP2018533930A (ja) * | 2015-10-02 | 2018-11-22 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 二重特異性ｔ細胞活性化抗原結合分子 |
| TW202519260A (zh) * | 2018-07-02 | 2025-05-16 | 美商安進公司 | 抗steap1抗原結合蛋白 |
| AU2019392090A1 (en) | 2018-12-03 | 2021-06-17 | Agensys, Inc. | Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof |
| EP4093439A1 (en) * | 2020-01-22 | 2022-11-30 | MedImmune Limited | Compounds and conjugates thereof |
| CN111494645B (zh) * | 2020-05-20 | 2022-09-30 | 中国药科大学 | 抗人dll4人源化抗体与美登素生物碱dm1的偶联物及其制备方法与应用 |
| EP4346908A4 (en) * | 2021-05-24 | 2026-04-29 | Remegen Co Ltd | USE OF AN ANTIBODY-DRUG CONJUGATE TARGETING HER2 IN THE TREATMENT OF LOW-EXPRESSING HER2 BREAST CANCER |
| KR20230015301A (ko) | 2021-07-19 | 2023-01-31 | 맙플렉스 인터내셔널 컴퍼니 리미티드 | 2성분 독소가 부하된 항체-약물 접합체 및 그의 용도 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1244705E (pt) * | 1999-12-06 | 2010-05-04 | Agensys Inc | Antigénios transmembranares em serpentina expressos em cancros da próstata humanos e suas utilizações |
| AU2004319915B9 (en) * | 2004-04-22 | 2011-12-22 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| DK1791565T3 (en) * | 2004-09-23 | 2016-08-01 | Genentech Inc | Cysteingensplejsede antibodies and conjugates |
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2007
- 2007-10-26 JP JP2009534901A patent/JP5394246B2/ja active Active
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2013
- 2013-10-18 JP JP2013217609A patent/JP5837019B2/ja active Active
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2015
- 2015-11-05 JP JP2015217734A patent/JP6185540B2/ja active Active