JP5394246B2 - 抗体及びイムノコンジュゲートとこれらの使用方法 - Google Patents
抗体及びイムノコンジュゲートとこれらの使用方法 Download PDFInfo
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- JP5394246B2 JP5394246B2 JP2009534901A JP2009534901A JP5394246B2 JP 5394246 B2 JP5394246 B2 JP 5394246B2 JP 2009534901 A JP2009534901 A JP 2009534901A JP 2009534901 A JP2009534901 A JP 2009534901A JP 5394246 B2 JP5394246 B2 JP 5394246B2
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| ES2874306T3 (es) | 2010-09-29 | 2021-11-04 | Agensys Inc | Conjugados de anticuerpos y fármacos (CAF) que se unen a las proteínas 191P4D12 |
| EP2621508B1 (de) * | 2010-09-29 | 2015-08-26 | Seattle Genetics, Inc. | N-carboxyalkyl-auristatine und ihre verwendung |
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| AU2012235817B2 (en) * | 2011-04-01 | 2016-03-10 | Wyeth Llc | Antibody-drug conjugates |
| HUE053589T2 (hu) | 2011-11-17 | 2021-07-28 | Pfizer | Citotoxikus peptidek és azok antitest-hatóanyag konjugátumai |
| AR089028A1 (es) * | 2011-11-29 | 2014-07-23 | Genentech Inc | Composiciones y metodos para el analisis de cancer de prostata |
| HK1206386A1 (en) * | 2012-04-04 | 2016-01-08 | Perseus Proteomics Inc. | Conjugate of anti-cdh3 (p-cadherin) antibody and drug |
| CN112587671A (zh) * | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| MY183572A (en) * | 2013-03-15 | 2021-02-26 | Regeneron Pharma | Biologically active molecules, conjugates thereof, and therapeutic uses |
| CA2936375A1 (en) * | 2014-01-10 | 2015-07-16 | Shanghai Birdie Biotech, Inc. | Compounds and compositions for treating her2 positive tumors |
| JP2017505305A (ja) * | 2014-01-24 | 2017-02-16 | ジェネンテック， インコーポレイテッド | 抗ｓｔｅａｐ１抗体及びイムノコンジュゲートを使用する方法 |
| TWI684600B (zh) * | 2014-03-21 | 2020-02-11 | 美商艾伯維有限公司 | 抗－ｅｇｆｒ抗體及抗體藥物結合物 |
| MX2017001022A (es) | 2014-07-24 | 2017-12-20 | Genentech Inc | Metodos para conjugar un agente a un resto tiol en una proteina que contiene al menos un enlace trisulfuro. |
| CN107949574A (zh) * | 2015-10-02 | 2018-04-20 | 豪夫迈·罗氏有限公司 | 双特异性t细胞活化性抗原结合分子 |
| SG11202013138RA (en) * | 2018-07-02 | 2021-01-28 | Amgen Inc | Anti-steap1 antigen-binding protein |
| KR20210100671A (ko) | 2018-12-03 | 2021-08-17 | 어젠시스 인코포레이티드 | 항-191p4d12 항체 약물 컨쥬게이트를 포함하는 약제학적 조성물 및 이의 사용 방법 |
| CA3166732A1 (en) * | 2020-01-22 | 2021-07-29 | Medimmune Limited | Compounds and conjugates thereof |
| CN111494645B (zh) * | 2020-05-20 | 2022-09-30 | 中国药科大学 | 抗人dll4人源化抗体与美登素生物碱dm1的偶联物及其制备方法与应用 |
| TW202313121A (zh) * | 2021-05-24 | 2023-04-01 | 中國大陸商榮昌生物製藥（煙臺）股份有限公司 | Her2靶向抗體-藥物結合物用於治療her2-低表現乳癌之用途 |
| WO2023000131A1 (zh) * | 2021-07-19 | 2023-01-26 | 烟台迈百瑞国际生物医药股份有限公司 | 一种负载双毒素的抗体药物偶联物及其应用 |
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| AU775366B2 (en) * | 1999-12-06 | 2004-07-29 | Agensys, Inc. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
| CN101258166B (zh) * | 2004-04-22 | 2013-01-30 | 阿根西斯公司 | 与steap-1蛋白结合的抗体及其衍生的分子 |
| SI1791565T1 (sl) * | 2004-09-23 | 2016-08-31 | Genentech, Inc. | Cisteinsko konstruirana protitelesa in konjugati |
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