JP5394246B2 - 抗体及びイムノコンジュゲートとこれらの使用方法 - Google Patents
抗体及びイムノコンジュゲートとこれらの使用方法 Download PDFInfo
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- JP5394246B2 JP5394246B2 JP2009534901A JP2009534901A JP5394246B2 JP 5394246 B2 JP5394246 B2 JP 5394246B2 JP 2009534901 A JP2009534901 A JP 2009534901A JP 2009534901 A JP2009534901 A JP 2009534901A JP 5394246 B2 JP5394246 B2 JP 5394246B2
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| EP2848686B1 (en) * | 2012-04-04 | 2024-12-25 | Perseus Proteomics Inc. | Conjugate of anti-cdh3 (p-cadherin) antibody and drug |
| CN103566377A (zh) * | 2012-07-18 | 2014-02-12 | 上海博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| EP2968593B1 (en) * | 2013-03-15 | 2024-11-20 | Regeneron Pharmaceuticals, Inc. | Biologically active molecules, conjugates thereof, and therapeutic uses |
| CN105899537A (zh) * | 2014-01-10 | 2016-08-24 | 博笛生物科技（北京）有限公司 | 靶向表达egfr的肿瘤的化合物和组合物 |
| AU2015209154A1 (en) * | 2014-01-24 | 2017-02-16 | Genentech, Inc. | Methods of using anti-STEAP1 antibodies and immunoconjugates |
| CA2942101A1 (en) * | 2014-03-21 | 2015-09-24 | Abbvie Inc. | Anti-egfr antibodies and antibody drug conjugates |
| RU2744978C2 (ru) | 2014-07-24 | 2021-03-17 | Дженентек, Инк. | Способы конъюгации агента с тиольным компонентом в белке, который содержит по меньшей мере одну трисульфидную связь |
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| WO2021148500A1 (en) * | 2020-01-22 | 2021-07-29 | Medimmune Limited | Compounds and conjugates thereof |
| CN111494645B (zh) * | 2020-05-20 | 2022-09-30 | 中国药科大学 | 抗人dll4人源化抗体与美登素生物碱dm1的偶联物及其制备方法与应用 |
| MX2023013619A (es) * | 2021-05-24 | 2023-11-30 | Remegen Co Ltd | Uso de conjugado farmaco-anticuerpo dirigido al her2 en el tratamiento del cancer de mama con expresion baja de her2. |
| CN113710277B (zh) * | 2021-07-19 | 2023-09-01 | 烟台迈百瑞国际生物医药股份有限公司 | 一种负载双毒素的抗体药物偶联物及其应用 |
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| NZ550816A (en) * | 2004-04-22 | 2009-12-24 | Agensys Inc | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| BRPI0516284A (pt) * | 2004-09-23 | 2008-09-02 | Genentech Inc | anticorpo construìdo com cisteìna, método de selecionar anticorpos, compostos conjugados de droga-anticorpo, composição farmacêutica, método para matar ou inibir a proliferação de células de tumor, métodos de inibir a proliferação celular e o crescimento de células de tumor, artigo manufaturado e método para produzir um composto |
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| JP2010523469A (ja) | 2010-07-15 |
| JP5837019B2 (ja) | 2015-12-24 |
| JP2014042522A (ja) | 2014-03-13 |
| JP2016063817A (ja) | 2016-04-28 |
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