JP5394246B2 - 抗体及びイムノコンジュゲートとこれらの使用方法 - Google Patents
抗体及びイムノコンジュゲートとこれらの使用方法 Download PDFInfo
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- JP5394246B2 JP5394246B2 JP2009534901A JP2009534901A JP5394246B2 JP 5394246 B2 JP5394246 B2 JP 5394246B2 JP 2009534901 A JP2009534901 A JP 2009534901A JP 2009534901 A JP2009534901 A JP 2009534901A JP 5394246 B2 JP5394246 B2 JP 5394246B2
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| MX347954B (es) * | 2010-09-29 | 2017-05-19 | Agensys Inc | Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. |
| JP5933562B2 (ja) * | 2010-09-29 | 2016-06-15 | シアトル ジェネティックス， インコーポレイテッド | Ｎ−カルボキシアルキル−アウリスタチンおよびその使用 |
| WO2012064836A1 (en) * | 2010-11-10 | 2012-05-18 | Genentech, Inc. | Methods and compositions for neural disease immunotherapy |
| WO2012131527A1 (en) * | 2011-04-01 | 2012-10-04 | Wyeth Llc | Antibody-drug conjugates |
| CN104185477B (zh) * | 2011-11-17 | 2017-05-24 | 辉瑞公司 | 细胞毒性肽及其抗体‑药物缀合物 |
| MX350807B (es) * | 2011-11-29 | 2017-09-20 | Genentech Inc | Composiciones y metodos para el analisis de cancer de prostata. |
| CA2869704A1 (en) | 2012-04-04 | 2013-10-10 | Perseus Proteomics Inc. | Drug conjugate comprising anti-cdh3 (pcadherin) antibody |
| CN112587671A (zh) * | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| JP6847388B2 (ja) * | 2013-03-15 | 2021-03-31 | レゲネロン ファーマシューティカルス，インコーポレーテッド | 生物活性分子、そのコンジュゲート、及び治療用途 |
| DK3092256T3 (da) * | 2014-01-10 | 2022-06-20 | Birdie Biopharmaceuticals Inc | Forbindelser og sammensætninger til immunterapi |
| EP3096797A1 (en) * | 2014-01-24 | 2016-11-30 | F. Hoffmann-La Roche AG | Methods of using anti-steap1 antibodies and immunoconjugates |
| AR099812A1 (es) * | 2014-03-21 | 2016-08-17 | Abbvie Inc | Anticuerpos y conjugados de anticuerpo y fármaco anti-egfr |
| SG11201700365TA (en) * | 2014-07-24 | 2017-02-27 | Genentech Inc | Methods of conjugating an agent to a thiol moiety in a protein that contains at least one trisulfide bond |
| JP2018533930A (ja) * | 2015-10-02 | 2018-11-22 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 二重特異性ｔ細胞活性化抗原結合分子 |
| TW202519260A (zh) * | 2018-07-02 | 2025-05-16 | 美商安進公司 | 抗steap1抗原結合蛋白 |
| AU2019392090A1 (en) | 2018-12-03 | 2021-06-17 | Agensys, Inc. | Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof |
| EP4093439A1 (en) * | 2020-01-22 | 2022-11-30 | MedImmune Limited | Compounds and conjugates thereof |
| CN111494645B (zh) * | 2020-05-20 | 2022-09-30 | 中国药科大学 | 抗人dll4人源化抗体与美登素生物碱dm1的偶联物及其制备方法与应用 |
| EP4346908A4 (en) * | 2021-05-24 | 2026-04-29 | Remegen Co Ltd | USE OF AN ANTIBODY-DRUG CONJUGATE TARGETING HER2 IN THE TREATMENT OF LOW-EXPRESSING HER2 BREAST CANCER |
| KR20230015301A (ko) | 2021-07-19 | 2023-01-31 | 맙플렉스 인터내셔널 컴퍼니 리미티드 | 2성분 독소가 부하된 항체-약물 접합체 및 그의 용도 |
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| AU2004319915B9 (en) * | 2004-04-22 | 2011-12-22 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| DK1791565T3 (en) * | 2004-09-23 | 2016-08-01 | Genentech Inc | Cysteingensplejsede antibodies and conjugates |
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| JP6185540B2 (ja) | 2017-08-23 |
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