|
US8975376B2
(en)
*
|
2010-02-23 |
2015-03-10 |
Sanofi |
Anti-alpha2 integrin antibodies and their uses
|
|
TWI560199B
(en)
|
2010-08-31 |
2016-12-01 |
Sanofi Sa |
Peptide or peptide complex binding to α2 integrin and methods and uses involving the same
|
|
US9605320B2
(en)
*
|
2011-01-13 |
2017-03-28 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of predicting responsiveness of B cell lineage malignancies to active immunotherapy
|
|
US9683052B2
(en)
|
2011-03-25 |
2017-06-20 |
Glenmark Pharmaceuticals S.A. |
Hetero-dimeric immunoglobulins
|
|
AP2014007415A0
(en)
|
2011-07-11 |
2014-02-28 |
Glenmark Pharmaceuticals Sa |
Antibodies that bind to OX40 and their uses
|
|
HUE058855T2
(hu)
|
2011-08-16 |
2022-09-28 |
Morphosys Ag |
Kombinációs terápia, CD19 elleni ellenanyag és purinanalóg alkalmazásával
|
|
PL2744515T3
(pl)
|
2011-08-16 |
2022-05-30 |
Morphosys Ag |
Terapia skojarzona przeciwciałem anty-cd19 i iperytem azotowym
|
|
CA2886036A1
(en)
|
2012-09-25 |
2014-04-03 |
Ichnos Sciences SA |
Purification of hetero-dimeric immunoglobulins
|
|
AU2013328625B2
(en)
|
2012-10-12 |
2016-12-15 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
DK2906298T3
(en)
|
2012-10-12 |
2018-12-17 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
CN104837502B
(zh)
|
2012-10-12 |
2018-08-10 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其结合物
|
|
AU2013204922B2
(en)
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
|
EA201591153A1
(ru)
|
2013-01-02 |
2016-01-29 |
Гленмарк Фармасьютикалс С.А. |
Антитела, связывающиеся с tl1a, и их применение
|
|
AU2014240083C1
(en)
|
2013-03-15 |
2019-10-24 |
Celgene Corporation |
Modified T lymphocytes
|
|
UY35468A
(es)
*
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
WO2014210209A2
(en)
*
|
2013-06-27 |
2014-12-31 |
Abbvie Biotherapeutics Inc. |
Fc variants with improved complement activation
|
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
MX389160B
(es)
*
|
2013-10-31 |
2025-03-20 |
Hutchinson Fred Cancer Res |
Células no t efectoras y madre/progenitoras hematopoyéticas modificadas y usos de estas.
|
|
CN110627907B
(zh)
|
2013-11-04 |
2024-03-29 |
艾科诺斯科技股份有限公司 |
重靶向t细胞的异源二聚免疫球蛋白的产生
|
|
ES2918501T3
(es)
|
2013-12-19 |
2022-07-18 |
Novartis Ag |
Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
|
|
AU2015244039B2
(en)
|
2014-04-07 |
2021-10-21 |
Novartis Ag |
Treatment of cancer using anti-CD19 chimeric antigen receptor
|
|
US11041021B2
(en)
|
2014-05-23 |
2021-06-22 |
University Of Florida Research Foundation, Incorporated |
Car based immunotherapy
|
|
TWI750110B
(zh)
|
2014-07-21 |
2021-12-21 |
瑞士商諾華公司 |
使用人類化抗-bcma嵌合抗原受體治療癌症
|
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
EP2990416B1
(en)
|
2014-08-29 |
2018-06-20 |
GEMoaB Monoclonals GmbH |
Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2016061368A1
(en)
*
|
2014-10-15 |
2016-04-21 |
The Children's Hospital Of Philadelphia |
Compositions and methods for treating b-lymphoid malignancies
|
|
MA41480A
(fr)
|
2014-10-17 |
2017-12-19 |
Glenmark Pharmaceuticals Sa |
Anticorps qui se lient au ccr6 et leurs utilisations
|
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
|
CA2969456A1
(en)
|
2014-12-03 |
2016-06-09 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
|
US12428483B2
(en)
*
|
2014-12-22 |
2025-09-30 |
Systimmune, Inc. |
Bispecific tetravalent antibodies and methods of making and using thereof
|
|
WO2016134284A1
(en)
*
|
2015-02-19 |
2016-08-25 |
University Of Florida Research Foundation, Inc. |
Chimeric antigen receptors and uses thereof
|
|
GB201503742D0
(en)
|
2015-03-05 |
2015-04-22 |
Ucl Business Plc |
Chimeric antigen receptor
|
|
MX2017012939A
(es)
|
2015-04-08 |
2018-05-22 |
Novartis Ag |
Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19.
|
|
WO2016168769A1
(en)
*
|
2015-04-15 |
2016-10-20 |
The California Institute For Biomedical Research |
Chimeric receptor t cell switches for her2
|
|
WO2016176651A2
(en)
*
|
2015-04-29 |
2016-11-03 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
CN107995913B
(zh)
|
2015-05-18 |
2022-02-11 |
T细胞受体治疗公司 |
使用融合蛋白对tcr重编程的组合物和方法
|
|
LT3302550T
(lt)
|
2015-05-26 |
2019-11-11 |
Morphosys Ag |
Anti-cd19 antikūno ir brutono tirozino kinazės inhibitoriaus derinys ir jo naudojimas
|
|
US10493139B2
(en)
|
2015-07-24 |
2019-12-03 |
Innovative Cellular Therapeutics CO., LTD. |
Humanized anti-CD19 antibody and use thereof with chimeric antigen receptor
|
|
WO2018126369A1
(en)
|
2017-01-05 |
2018-07-12 |
Shanghai Sidansai Biotechnology Co., Ltd |
Humanized anti-cd19 antibody and use thereof with chimeric antigen receptor
|
|
WO2017015783A1
(en)
*
|
2015-07-24 |
2017-02-02 |
Shanghai Sidansai Biotechnology Co., Ltd |
Humanized anti-cd19 antibody and use thereof
|
|
SMT202100541T1
(it)
|
2015-08-21 |
2021-11-12 |
Morphosys Ag |
Combinazioni e loro usi
|
|
ES2980794T3
(es)
|
2015-09-15 |
2024-10-03 |
Acerta Pharma Bv |
Combinaciones terapéuticas de un inhibidor de CD19 y un inhibidor de BTK
|
|
AR106188A1
(es)
*
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
JP6918789B2
(ja)
|
2015-10-02 |
2021-08-11 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
高親和性を有する抗ヒトcdc19抗体
|
|
EP3356407B1
(en)
*
|
2015-10-02 |
2021-11-03 |
F. Hoffmann-La Roche AG |
Bispecific anti-cd19xcd3 t cell activating antigen binding molecules
|
|
CA3007258A1
(en)
*
|
2015-12-03 |
2017-06-08 |
Mark L. Bonyhadi |
Compositions and methods for reducing immune responses against cell therapies
|
|
CN108884140B
(zh)
|
2015-12-03 |
2022-10-25 |
朱诺治疗学股份有限公司 |
修饰的嵌合受体及相关组合物和方法
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
RS62155B1
(sr)
|
2016-05-30 |
2021-08-31 |
Morphosys Ag |
Postupci predviđanja terapijske koristi anti-cd19 terapije kod pacijenata
|
|
SI3475303T1
(sl)
|
2016-06-27 |
2021-12-31 |
Morphosys Ag |
Formulacija protitelesa proti CD19
|
|
EP3523331A1
(en)
|
2016-10-07 |
2019-08-14 |
Novartis AG |
Chimeric antigen receptors for the treatment of cancer
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
CN110267982B
(zh)
*
|
2016-10-19 |
2024-02-23 |
斯克利普斯研究所 |
具有人源化靶向部分和/或经过优化的嵌合抗原受体相互作用结构域的嵌合抗原受体效应细胞开关以及其用途
|
|
WO2018075820A2
(en)
|
2016-10-20 |
2018-04-26 |
Celgene Corporation |
Cereblon-based heterodimerizable chimeric antigen receptors
|
|
IL301786B2
(en)
|
2016-10-28 |
2025-09-01 |
Morphosys Ag |
Combination of anti-CD19 antibody with BCL-2 inhibitor and their uses
|
|
US11851491B2
(en)
|
2016-11-22 |
2023-12-26 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
|
CN110352068A
(zh)
|
2016-12-02 |
2019-10-18 |
南加利福尼亚大学 |
合成的免疫受体及其使用方法
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
MX375569B
(es)
|
2017-02-08 |
2025-03-04 |
Adc Therapeutics Sa |
Conjugados de pirrolobenzodiazepinas y anticuerpos
|
|
CN106967171B
(zh)
*
|
2017-02-23 |
2021-04-27 |
郑州大学 |
一种全人源重组CD40L单抗Fab片段及其制备方法
|
|
PT3612537T
(pt)
|
2017-04-18 |
2022-08-29 |
Medimmune Ltd |
Conjugados de pirrolobenzodiazepina
|
|
WO2018195339A1
(en)
|
2017-04-19 |
2018-10-25 |
Board Of Regents, The University Of Texas System |
Immune cells expressing engineered antigen receptors
|
|
SG10201912400VA
(en)
*
|
2017-04-24 |
2020-02-27 |
Kite Pharma Inc |
Humanized antigen-binding domains against cd19 and methods of use
|
|
KR20250067964A
(ko)
|
2017-05-10 |
2025-05-15 |
더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 |
최적화된 핵산 항체 작제물
|
|
HRP20231229T1
(hr)
|
2017-05-31 |
2024-02-02 |
Morphosys Ag |
Paradigma liječenja za protutijelo anti-cd19 i venetoklaks kombinacijsko liječenje
|
|
MX2019015042A
(es)
|
2017-06-14 |
2020-08-06 |
Adc Therapeutics Sa |
Regimen de dosificacion.
|
|
WO2019011918A1
(en)
|
2017-07-10 |
2019-01-17 |
International - Drug - Development - Biotech |
TREATMENT OF LYMPHOCYTE B MALIGNANCIES USING AFUCOSYLATED PRO-APOPTOTIC ANTI-CD19 ANTIBODIES IN COMBINATION WITH ANTI-CD20 ANTIBODIES OR CHEMOTHERAPEUTIC AGENTS
|
|
WO2019016392A1
(en)
|
2017-07-20 |
2019-01-24 |
Nbe-Therapeutics Ag |
HUMAN ANTIBODIES BINDING TO ROR2
|
|
DK3668874T3
(da)
|
2017-08-18 |
2022-02-14 |
Medimmune Ltd |
Pyrrolobenzodiazepin-konjugater
|
|
TWI878186B
(zh)
*
|
2017-09-21 |
2025-03-21 |
中國大陸商上海藥明生物技術有限公司 |
新型抗cd19抗體
|
|
EP3703675A4
(en)
|
2017-10-30 |
2021-06-16 |
Neuropore Therapies, Inc. |
SUBSTITUTED PHENYLSULFONYLPHÉNYLTRIAZOLETHIONES AND ASSOCIATED USES
|
|
KR102136063B1
(ko)
|
2017-12-06 |
2020-07-22 |
앱클론(주) |
악성 b 세포를 특이적으로 인지하는 항체 또는 그의 항원 결합 단편, 이를 포함하는 키메라 항체 수용체 및 이의 용도
|
|
CN109053899B
(zh)
|
2017-12-22 |
2021-11-16 |
湖南远泰生物技术有限公司 |
一种含人转铁蛋白抗原表位序列的嵌合体抗原受体
|
|
EP3730519B1
(en)
*
|
2017-12-22 |
2023-09-13 |
AbClon Inc. |
Antibody or antigen-binding fragment thereof that specifically recognizes b cell malignancies, chimeric antigen receptor comprising same, and uses thereof
|
|
CN108047332B
(zh)
*
|
2018-01-15 |
2021-08-24 |
阿思科力(苏州)生物科技有限公司 |
以cd19为靶点的特异性抗体、car-nk细胞及其制备和应用
|
|
JP7273421B2
(ja)
|
2018-02-21 |
2023-05-15 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用
|
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CA3100724A1
(en)
|
2018-06-13 |
2019-12-19 |
Novartis Ag |
B-cell maturation antigen protein (bcma) chimeric antigen receptors and uses thereof
|
|
KR20200030337A
(ko)
|
2018-09-12 |
2020-03-20 |
주식회사 녹십자랩셀 |
종양 치료를 위한 항-cd 19 항체 및 자연살해세포를 포함하는 약학적 조합물
|
|
CN109293774B
(zh)
*
|
2018-10-16 |
2021-05-28 |
南京医科大学 |
特异性结合cd19的全人源化抗体及应用
|
|
US20220249814A1
(en)
|
2018-11-19 |
2022-08-11 |
Progenity, Inc. |
Methods and devices for treating a disease with biotherapeutics
|
|
US12590148B2
(en)
|
2018-11-26 |
2026-03-31 |
Nkarta, Inc. |
Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
|
|
KR102840400B1
(ko)
|
2018-12-12 |
2025-08-04 |
카이트 파마 인코포레이티드 |
키메라 항원 수용체 및 car-t 세포 및 사용 방법
|
|
SG10202105788SA
(en)
|
2018-12-21 |
2021-06-29 |
Hoffmann La Roche |
Antibodies binding to cd3
|
|
JP7090780B2
(ja)
*
|
2018-12-21 |
2022-06-24 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Cd3に結合する抗体
|
|
AU2020232691B2
(en)
*
|
2019-03-05 |
2023-06-29 |
Nkarta, Inc. |
CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
KR102890251B1
(ko)
|
2019-03-15 |
2025-11-25 |
메드임뮨 리미티드 |
암의 치료에 사용하기 위한 아제티도벤조디아제핀 이량체 및 이를 포함하는 컨쥬게이트
|
|
JP7730295B2
(ja)
*
|
2019-04-08 |
2025-08-27 |
メモリアル スローン ケタリング キャンサー センター |
Cd19抗体およびこれを使用する方法
|
|
US20220249558A1
(en)
*
|
2019-04-30 |
2022-08-11 |
Crispr Therapeutics Ag |
Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19
|
|
MX2021013101A
(es)
|
2019-05-03 |
2022-01-04 |
Morphosys Ag |
Terapia anti-cd19 en pacientes que tienen una cantidad limitada de células nk.
|
|
CA3144871A1
(en)
*
|
2019-06-27 |
2020-12-30 |
Crispr Therapeutics Ag |
Use of chimeric antigen receptor t cells and nk cell inhibitors for treating cancer
|
|
AU2020311511B2
(en)
|
2019-07-09 |
2024-08-29 |
Beijing Solobio Genetechnology Co., Ltd. |
Antibodies specifically recognizing Pseudomonas PcrV and uses thereof
|
|
CN110396129B
(zh)
*
|
2019-07-10 |
2020-11-24 |
武汉思安医疗技术有限公司 |
人源化cd19抗原结合单链抗体及其嵌合抗原受体、免疫细胞和应用
|
|
US12544437B2
(en)
|
2019-10-04 |
2026-02-10 |
Ultragenyx Pharmaceutical Inc. |
Methods for improved therapeutic use of recombinant AAV
|
|
US20210130461A1
(en)
|
2019-10-31 |
2021-05-06 |
Morphosys Ag |
Anti-tumor combination therapy comprising anti-cd19 antibody and gamma delta t-cells
|
|
TWI865644B
(zh)
|
2019-10-31 |
2024-12-11 |
德商莫菲西斯公司 |
用於治療白血病或淋巴瘤之抗cd19療法與來那度胺(lenalidomide)的組合
|
|
PH12022551291A1
(en)
|
2019-11-26 |
2023-11-20 |
Novartis Ag |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
CN121197633A
(zh)
|
2019-12-13 |
2025-12-26 |
比特比德科有限责任公司 |
用于将治疗剂递送至胃肠道的可摄取装置
|
|
JP2023513282A
(ja)
*
|
2020-02-11 |
2023-03-30 |
クリスパー セラピューティクス アクチェンゲゼルシャフト |
抗cd19キメラ抗原受容体を標的とする抗イディオタイプ抗体
|
|
US20210340524A1
(en)
*
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
BR112022025856A2
(pt)
|
2020-06-19 |
2023-01-10 |
Hoffmann La Roche |
Anticorpo que se liga a cd3 e cd19, polinucleotídeo isolado, célula hospedeira, método de produção de um anticorpo que se liga a cd3 e cd19, composição farmacêutica, uso do anticorpo, método para tratar uma doença em um indivíduo e invenção
|
|
US20230014026A1
(en)
|
2020-06-22 |
2023-01-19 |
Morphosys Ag |
Anti-Tumor Combination Therapy comprising Anti-CD19 Antibody and Polypeptides Blocking the SIRPalpha-CD47 Innate Immune Checkpoint
|
|
EP4225794A1
(en)
|
2020-10-06 |
2023-08-16 |
Xencor, Inc. |
Biomarkers, methods, and compositions for treating autoimmune disease including systemic lupus erythematous (sle)
|
|
CN116848147A
(zh)
*
|
2020-11-20 |
2023-10-03 |
先声再明医药有限公司 |
Cd19人源化抗体及其应用
|
|
US20220184208A1
(en)
|
2020-12-04 |
2022-06-16 |
Morphosys Ag |
Anti-cd19 combination therapy
|
|
WO2022155375A2
(en)
*
|
2021-01-13 |
2022-07-21 |
Washington University |
MHC-INDEPENDENT TCRs AND METHODS OF MAKING AND USING SAME
|
|
CN112679612B
(zh)
*
|
2021-01-29 |
2022-07-01 |
武汉华美生物工程有限公司 |
抗cd19人源化抗体及其制备方法与应用
|
|
IL308296A
(en)
*
|
2021-05-07 |
2024-01-01 |
Viela Bio Inc |
Use of anti-CD19 antibody to treat myasthenia gravis
|
|
WO2023073645A1
(en)
|
2021-10-29 |
2023-05-04 |
Takeda Pharmaceutical Company Limited |
Therapy comprising anti-cd19 antibody and sumo-activating enzyme inhibitor
|
|
US20250084169A1
(en)
|
2022-01-12 |
2025-03-13 |
Biomolecular Holdings Llc |
Nk/monocyte engagers
|
|
IL318787A
(en)
|
2022-08-17 |
2025-04-01 |
Incyte Corp |
Treatment including ANTI-CD19 antibodies and EZH2 modulators
|
|
EP4703374A1
(en)
*
|
2023-04-28 |
2026-03-04 |
Shenzhen Shenxin Biotechnology Co., Ltd. |
Modified delivery vector and use thereof
|
|
WO2024251263A1
(en)
|
2023-06-09 |
2024-12-12 |
Jw Therapeutics R & D (Shanghai) Co., Ltd. |
Fusion protein and medical use thereof
|
|
US20250197501A1
(en)
*
|
2023-12-19 |
2025-06-19 |
Development Center For Biotechnology |
Recombinant antibody, immunoconjugate comprising the same, and uses thereof in treating cancers
|