JP2012512910A5 - - Google Patents

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JP2012512910A5
JP2012512910A5 JP2011542519A JP2011542519A JP2012512910A5 JP 2012512910 A5 JP2012512910 A5 JP 2012512910A5 JP 2011542519 A JP2011542519 A JP 2011542519A JP 2011542519 A JP2011542519 A JP 2011542519A JP 2012512910 A5 JP2012512910 A5 JP 2012512910A5
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cell
cells
express
umbilical cord
medicament according
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JP2011542519A
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JP6095893B2 (ja
JP2012512910A (ja
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Priority claimed from PCT/US2009/068880 external-priority patent/WO2010071863A1/en
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JP2011542519A 2008-12-19 2009-12-19 傷害後の神経組織の再生および修復 Expired - Fee Related JP6095893B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13930508P 2008-12-19 2008-12-19
US61/139,305 2008-12-19
PCT/US2009/068880 WO2010071863A1 (en) 2008-12-19 2009-12-19 Regeneration and repair of neural tissue following injury

Publications (3)

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JP2012512910A JP2012512910A (ja) 2012-06-07
JP2012512910A5 true JP2012512910A5 (https=) 2013-05-02
JP6095893B2 JP6095893B2 (ja) 2017-03-15

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JP2011542519A Expired - Fee Related JP6095893B2 (ja) 2008-12-19 2009-12-19 傷害後の神経組織の再生および修復

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US (1) US20100158880A1 (https=)
EP (1) EP2379089B1 (https=)
JP (1) JP6095893B2 (https=)
CN (1) CN102458425A (https=)
AU (1) AU2009327383B2 (https=)
BR (1) BRPI0923070A2 (https=)
CA (1) CA2747758C (https=)
WO (1) WO2010071863A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7875272B2 (en) * 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
US8518390B2 (en) 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US8491883B2 (en) * 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
EP2399990B1 (en) 2003-06-27 2015-07-22 DePuy Synthes Products, Inc. Cells derived from post-partum umbilical cord for use in treatment of disease of the heart and circulatory system
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
CN101611139B (zh) 2006-11-13 2012-07-04 伊西康公司 利用微载体的产后来源的细胞的体外扩增
ES2525718T3 (es) * 2007-10-05 2014-12-29 DePuy Synthes Products, LLC Reparación y regeneración de tejido renal mediante células derivadas de tejido de cordón umbilical humano
US8236538B2 (en) 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
UA99167C2 (ru) * 2007-12-27 2012-07-25 Этикон, Инкорпорейтед Лечение дегенерации межреберных дисков с использованием клеток, полученных из ткани пуповины человека
US10179900B2 (en) 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
JP5518893B2 (ja) 2008-12-19 2014-06-11 アドバンスト・テクノロジーズ・アンド・リジェネレイティブ・メディスン・エルエルシー 肺ならびに肺の疾患および障害の治療
EP2411504B1 (en) * 2009-03-26 2017-05-10 DePuy Synthes Products, Inc. Human umbilical cord tissue cells as therapy for alzheimer's disease
WO2011068792A2 (en) * 2009-12-01 2011-06-09 The Regents Of The University Of California Compositions and methods for making and using bone marrow mesenchymal stem cells and erythroid progenitor cells
US9045657B2 (en) * 2010-03-24 2015-06-02 The Board Of Trustees Of The University Of Illinois Viscoelastic ink for direct writing of hydrogel structures
EP2794854B1 (en) * 2011-12-23 2018-06-20 DePuy Synthes Products, Inc. Detection of human umbilical cord tissue-derived cells
RU2539750C2 (ru) * 2013-04-09 2015-01-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ оценки иммуносупрессивных свойств мезенхимальных стромальных клеток человека
WO2015017775A2 (en) * 2013-08-01 2015-02-05 Parcell Laboratories, Llc Compositions having early lineage adult stem cells and extracts thereof
CA2943088A1 (en) * 2014-03-20 2015-10-01 Patrick J. Casey Method for the treatment of damaged tissue
US20180236004A1 (en) * 2015-08-15 2018-08-23 Asterias Biotherapeutics, Inc. Stem cell-derived oligodendrocyte progenitor cells for the treatment of white matter stroke
US10662409B2 (en) 2015-09-09 2020-05-26 Trustees Of Tufts College Methods of generating neural stem cells
JP6967308B1 (ja) * 2020-06-30 2021-11-17 国立大学法人高知大学 胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤
US11844876B2 (en) 2021-01-25 2023-12-19 BioStem Tehcnologies, Inc. Two-part clotting composition and methods of making and using thereof
CN114561355B (zh) * 2022-01-23 2023-04-11 四川大学华西医院 一种脊髓瘢痕组织细胞急性快速分离方法
WO2024124507A1 (en) * 2022-12-15 2024-06-20 Center For Excellence In Brain Science And Intelligence Technology, Chinese Academy Of Sciences Striatal neural progenitors in treatment of hypoxic-ischemic encephalopathy
CN118962134A (zh) * 2023-05-15 2024-11-15 上海交通大学医学院附属仁济医院 Ch25h+抑炎型小胶质细胞在缺血性脑卒中治疗中的应用

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3665061A (en) * 1969-07-16 1972-05-23 United States Banknote Corp Process for producing collagen sponges
JPS5651747B2 (https=) * 1973-05-31 1981-12-08
US5902741A (en) * 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5004681B1 (en) * 1987-11-12 2000-04-11 Biocyte Corp Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
US5192553A (en) * 1987-11-12 1993-03-09 Biocyte Corporation Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use
US20030032178A1 (en) * 1988-08-04 2003-02-13 Williams Robert Lindsay In vitro propagation of embryonic stem cells
US4925677A (en) * 1988-08-31 1990-05-15 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5286632A (en) * 1991-01-09 1994-02-15 Jones Douglas H Method for in vivo recombination and mutagenesis
US6399369B1 (en) * 1991-07-08 2002-06-04 Neurospheres Holdings Ltd. Multipotent neural stem cell cDNA libraries
US5320962A (en) * 1992-07-22 1994-06-14 Duke University DNA encoding the human A1 adenosine receptor
US5707643A (en) * 1993-02-26 1998-01-13 Santen Pharmaceutical Co., Ltd. Biodegradable scleral plug
JP3680114B2 (ja) * 1993-09-17 2005-08-10 敏一 中村 脳神経障害治療剤
US6686198B1 (en) * 1993-10-14 2004-02-03 President And Fellows Of Harvard College Method of inducing and maintaining neuronal cells
US6703017B1 (en) * 1994-04-28 2004-03-09 Ixion Biotechnology, Inc. Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures
CA2192103C (en) * 1994-06-06 2002-02-05 Arnold I. Caplan Biomatrix for tissue regeneration
US5725493A (en) * 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5906934A (en) * 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
US5641750A (en) * 1995-11-29 1997-06-24 Amgen Inc. Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product
US6200606B1 (en) * 1996-01-16 2001-03-13 Depuy Orthopaedics, Inc. Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration
US6358737B1 (en) * 1996-07-31 2002-03-19 Board Of Regents, The University Of Texas System Osteocyte cell lines
US6787355B1 (en) * 1996-08-26 2004-09-07 Mcgill University Multipotent neural stem cells from peripheral tissues and uses thereof
EP0983062A4 (en) * 1997-05-21 2002-10-23 Sloan Kettering Inst Cancer METHOD FOR INCREASING THE CONCENTRATION OF ASCOBIC ACID IN PERSONAL BRAIN TISSUE
JP4132089B2 (ja) * 1997-05-30 2008-08-13 オステオバイオロジックス,インコーポレイテッド 繊維強化多孔性生体分解性移植デバイス
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
CA2312847C (en) * 1997-12-02 2014-09-30 Zen Bio, Inc. Differentiation of adipose stromal cells into osteoblasts and uses thereof
US6059968A (en) * 1998-01-20 2000-05-09 Baxter International Inc. Systems for processing and storing placenta/umbilical cord blood
AU749675B2 (en) * 1998-03-13 2002-07-04 Mesoblast International Sarl Uses for human non-autologous mesenchymal stem cells
US6171610B1 (en) * 1998-04-24 2001-01-09 University Of Massachusetts Guided development and support of hydrogel-cell compositions
WO1999056759A1 (en) * 1998-05-07 1999-11-11 University Of South Florida Bone marrow cells as a source of neurons for brain and spinal cord repair
PT1082410E (pt) * 1998-05-29 2007-11-09 Osiris Therapeutics Inc Células estaminais mesenquimatosas humanas cd45+ e/ou fibroblastos+
US20040037818A1 (en) * 1998-07-30 2004-02-26 Brand Stephen J. Treatment for diabetes
US5958767A (en) * 1998-08-14 1999-09-28 The Children's Medical Center Corp. Engraftable human neural stem cells
US6610540B1 (en) * 1998-11-18 2003-08-26 California Institute Of Technology Low oxygen culturing of central nervous system progenitor cells
US20030007954A1 (en) * 1999-04-12 2003-01-09 Gail K. Naughton Methods for using a three-dimensional stromal tissue to promote angiogenesis
JP2002542349A (ja) * 1999-04-16 2002-12-10 ダブリューエム・マーシュ・ライス・ユニバーシティー ポリ(プロピレンフマラート)−ジアクリレートマクロマーで交差結合された生体分解性のポリ(プロピレンフマラート)ネットワーク
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
US6287340B1 (en) * 1999-05-14 2001-09-11 Trustees Of Tufts College Bioengineered anterior cruciate ligament
US6333029B1 (en) * 1999-06-30 2001-12-25 Ethicon, Inc. Porous tissue scaffoldings for the repair of regeneration of tissue
US6555374B1 (en) * 1999-08-19 2003-04-29 Artecel Sciences, Inc. Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
US20030129745A1 (en) * 1999-10-28 2003-07-10 Robl James M. Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues
US20030082155A1 (en) * 1999-12-06 2003-05-01 Habener Joel F. Stem cells of the islets of langerhans and their use in treating diabetes mellitus
US20010046489A1 (en) * 1999-12-06 2001-11-29 Habener Joel E. Stem cells of the islets of langerhans and their use in treating diabetes mellitus
US7544509B2 (en) * 2000-01-24 2009-06-09 Mcgill University Method for preparing stem cell preparations
EP1263930A4 (en) * 2000-03-09 2004-07-21 Saneron Ccel Therapeutics Inc HUMAN CORD BLOOD BLOOD AS A SOURCE FOR NEURAL TISSUE FOR HEALING THE BRAIN AND BACK MARK
US6673606B1 (en) * 2000-04-12 2004-01-06 The Children's Hospital Of Philadelphia Therapeutic uses for mesenchymal stromal cells
US6375972B1 (en) * 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US6759039B2 (en) * 2000-06-30 2004-07-06 Amcyte, Inc. Culturing pancreatic stem cells having a specified, intermediate stage of development
EP2316918B1 (en) * 2001-02-14 2015-07-01 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
US20030022369A1 (en) * 2001-05-18 2003-01-30 Helen Fillmore Differentiation of specialized dermal and epidermal cells into neuronal cells
EP1401282A4 (en) * 2001-05-25 2005-03-30 Cythera Inc DIFFERENTIATION OF STEM CELLS
AU2002313817A1 (en) * 2001-08-27 2003-03-10 Advanced Cell Technology, Inc. Trans-differentiation and re-differentiation of somatic cells and production of cells for cell therapies
US20030104997A1 (en) * 2001-09-05 2003-06-05 Black Ira B. Multi-lineage directed induction of bone marrow stromal cell differentiation
US7129034B2 (en) * 2001-10-25 2006-10-31 Cedars-Sinai Medical Center Differentiation of whole bone marrow
JP3728750B2 (ja) * 2001-11-22 2005-12-21 ニプロ株式会社 培養皮膚及びその製造方法
AU2002341725A1 (en) * 2001-12-06 2003-07-09 The Regents Of The University Of California Method for differentiating islet precursor cells into beta cells
EP1458854B1 (en) * 2001-12-21 2010-04-14 Mount Sinai Hospital Cellular compositions and methods of making and using them
US20030162290A1 (en) * 2002-01-25 2003-08-28 Kazutomo Inoue Method for inducing differentiation of embryonic stem cells into functioning cells
US20040029269A1 (en) * 2002-05-07 2004-02-12 Goldman Steven A Promoter-based isolation, purification, expansion, and transplantation of neuronal progenitor cells, oligodendrocyte progenitor cells, or neural stem cells from a population of embryonic stem cells
WO2003094965A2 (en) * 2002-05-08 2003-11-20 Neuronova Ab Modulation of neural stem cells with s1p or lpa receptor agonists
CA2488013A1 (en) * 2002-05-30 2003-12-11 Celgene Corporation Methods of using jnk or mkk inhibitors to modulate cell differentiation and to treat myeloproliferative disorders and myelodysplastic syndromes
AU2003247514A1 (en) * 2002-06-11 2003-12-22 Roy Ogle Meningeal-derived stem cells
US7285415B2 (en) * 2002-07-11 2007-10-23 The Regents Of The University Of California Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US7390659B2 (en) * 2002-07-16 2008-06-24 The Trustees Of Columbia University In The City Of New York Methods for inducing differentiation of embryonic stem cells and uses thereof
US20040063202A1 (en) * 2002-08-28 2004-04-01 Petersen Bryon E. Neurogenesis from hepatic stem cells
US9969977B2 (en) * 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
CN1770976A (zh) * 2003-02-13 2006-05-10 人类起源公司 利用脐带血治疗患有疾病、紊乱或状况的个体的用途
US7875272B2 (en) * 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
EP2399990B1 (en) * 2003-06-27 2015-07-22 DePuy Synthes Products, Inc. Cells derived from post-partum umbilical cord for use in treatment of disease of the heart and circulatory system
US20050089513A1 (en) * 2003-10-28 2005-04-28 Norio Sakuragawa Side population cells originated from human amnion and their uses
US7833513B2 (en) * 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
EP1835924B1 (en) * 2004-12-23 2013-08-21 Ethicon, Incorporated Treatment of parkinson's disease and related disorders using postpartum derived cells
CA2589041C (en) * 2004-12-23 2019-08-20 DePuy Synthes Products, Inc. Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
US20070025973A1 (en) * 2005-07-29 2007-02-01 Fitzsimmons Frederick J Reprogramming of adult or neonic stem cells and methods of use
US7923007B2 (en) * 2005-08-08 2011-04-12 Academia Sinica Brain tissue damage therapies
US8372399B2 (en) * 2006-08-31 2013-02-12 Cardiac Pacemakers, Inc. Bispecific antibodies and agents to enhance stem cell homing
CN101595212B (zh) * 2006-10-12 2014-04-30 伊西康公司 肾源细胞及在组织修复和再生中的使用方法
MX2009013726A (es) * 2007-06-15 2010-01-25 Ethicon Inc Composiciones de celulas derivadas de tejido umbilical humano para el tratamiento de la incontinencia.
AU2008201946B2 (en) * 2007-09-13 2014-07-03 Librach, Clifford L Method of Isolation and Use of Cells Derived From First Trimester Umbilical Cord Tissue
ES2525718T3 (es) * 2007-10-05 2014-12-29 DePuy Synthes Products, LLC Reparación y regeneración de tejido renal mediante células derivadas de tejido de cordón umbilical humano
EP2411504B1 (en) * 2009-03-26 2017-05-10 DePuy Synthes Products, Inc. Human umbilical cord tissue cells as therapy for alzheimer's disease

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