CA2747758C - Regeneration and repair of neural tissue following injury - Google Patents

Regeneration and repair of neural tissue following injury Download PDF

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Publication number
CA2747758C
CA2747758C CA2747758A CA2747758A CA2747758C CA 2747758 C CA2747758 C CA 2747758C CA 2747758 A CA2747758 A CA 2747758A CA 2747758 A CA2747758 A CA 2747758A CA 2747758 C CA2747758 C CA 2747758C
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cells
umbilical cord
cell
cord tissue
derived cells
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CA2747758A
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English (en)
French (fr)
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CA2747758A1 (en
Inventor
Agnieszka Seyda
Anna Gosiewska
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DePuy Synthes Products Inc
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DePuy Synthes Products Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
CA2747758A 2008-12-19 2009-12-19 Regeneration and repair of neural tissue following injury Active CA2747758C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13930508P 2008-12-19 2008-12-19
US61/139,305 2008-12-19
PCT/US2009/068880 WO2010071863A1 (en) 2008-12-19 2009-12-19 Regeneration and repair of neural tissue following injury

Publications (2)

Publication Number Publication Date
CA2747758A1 CA2747758A1 (en) 2010-06-24
CA2747758C true CA2747758C (en) 2020-09-22

Family

ID=42097221

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2747758A Active CA2747758C (en) 2008-12-19 2009-12-19 Regeneration and repair of neural tissue following injury

Country Status (8)

Country Link
US (1) US20100158880A1 (https=)
EP (1) EP2379089B1 (https=)
JP (1) JP6095893B2 (https=)
CN (1) CN102458425A (https=)
AU (1) AU2009327383B2 (https=)
BR (1) BRPI0923070A2 (https=)
CA (1) CA2747758C (https=)
WO (1) WO2010071863A1 (https=)

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US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US8491883B2 (en) * 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
EP2399990B1 (en) 2003-06-27 2015-07-22 DePuy Synthes Products, Inc. Cells derived from post-partum umbilical cord for use in treatment of disease of the heart and circulatory system
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
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ES2525718T3 (es) * 2007-10-05 2014-12-29 DePuy Synthes Products, LLC Reparación y regeneración de tejido renal mediante células derivadas de tejido de cordón umbilical humano
US8236538B2 (en) 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
UA99167C2 (ru) * 2007-12-27 2012-07-25 Этикон, Инкорпорейтед Лечение дегенерации межреберных дисков с использованием клеток, полученных из ткани пуповины человека
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JP6967308B1 (ja) * 2020-06-30 2021-11-17 国立大学法人高知大学 胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤
US11844876B2 (en) 2021-01-25 2023-12-19 BioStem Tehcnologies, Inc. Two-part clotting composition and methods of making and using thereof
CN114561355B (zh) * 2022-01-23 2023-04-11 四川大学华西医院 一种脊髓瘢痕组织细胞急性快速分离方法
WO2024124507A1 (en) * 2022-12-15 2024-06-20 Center For Excellence In Brain Science And Intelligence Technology, Chinese Academy Of Sciences Striatal neural progenitors in treatment of hypoxic-ischemic encephalopathy
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Also Published As

Publication number Publication date
AU2009327383B2 (en) 2014-08-28
JP6095893B2 (ja) 2017-03-15
CA2747758A1 (en) 2010-06-24
US20100158880A1 (en) 2010-06-24
EP2379089B1 (en) 2019-04-17
JP2012512910A (ja) 2012-06-07
CN102458425A (zh) 2012-05-16
AU2009327383A1 (en) 2011-08-11
BRPI0923070A2 (pt) 2016-06-14
WO2010071863A1 (en) 2010-06-24
EP2379089A1 (en) 2011-10-26

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