CN102458425A - 损伤后神经组织的再生和修复 - Google Patents

损伤后神经组织的再生和修复 Download PDF

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Publication number
CN102458425A
CN102458425A CN2009801570086A CN200980157008A CN102458425A CN 102458425 A CN102458425 A CN 102458425A CN 2009801570086 A CN2009801570086 A CN 2009801570086A CN 200980157008 A CN200980157008 A CN 200980157008A CN 102458425 A CN102458425 A CN 102458425A
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cell
utc
tissue
source
damage
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CN2009801570086A
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Chinese (zh)
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A.赛达
A.戈谢夫斯卡
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Depp Iraq Orthopedic Co
DePuy Spine LLC
DePuy Synthes Products Inc
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Ethicon Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
CN2009801570086A 2008-12-19 2009-12-19 损伤后神经组织的再生和修复 Pending CN102458425A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13930508P 2008-12-19 2008-12-19
US61/139,305 2008-12-19
PCT/US2009/068880 WO2010071863A1 (en) 2008-12-19 2009-12-19 Regeneration and repair of neural tissue following injury

Publications (1)

Publication Number Publication Date
CN102458425A true CN102458425A (zh) 2012-05-16

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801570086A Pending CN102458425A (zh) 2008-12-19 2009-12-19 损伤后神经组织的再生和修复

Country Status (8)

Country Link
US (1) US20100158880A1 (https=)
EP (1) EP2379089B1 (https=)
JP (1) JP6095893B2 (https=)
CN (1) CN102458425A (https=)
AU (1) AU2009327383B2 (https=)
BR (1) BRPI0923070A2 (https=)
CA (1) CA2747758C (https=)
WO (1) WO2010071863A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024125295A1 (en) * 2022-12-15 2024-06-20 Center For Excellence In Brain Science And Intelligence Technology, Chinese Academy Of Sciences Striatal neural progenitors in treatment of hypoxic-ischemic encephalopathy
CN118962134A (zh) * 2023-05-15 2024-11-15 上海交通大学医学院附属仁济医院 Ch25h+抑炎型小胶质细胞在缺血性脑卒中治疗中的应用

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US8491883B2 (en) * 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
US8518390B2 (en) 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
US8790637B2 (en) * 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
WO2005001080A2 (en) 2003-06-27 2005-01-06 Ethicon, Incorporated Postpartum-derived cells for use in treatment of disease of the heart and circulatory system
US7875272B2 (en) * 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
PL2089511T3 (pl) 2006-11-13 2015-02-27 Depuy Synthes Products Llc Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki
JP5323845B2 (ja) * 2007-10-05 2013-10-23 エシコン・インコーポレイテッド ヒト臍帯組織由来細胞を用いた腎組織の修復および再建
US8236538B2 (en) 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
BRPI0821489A2 (pt) * 2007-12-27 2015-06-16 Ethicon Inc Tratamento de degeneração do disco intervetebral com o uso de células derivadas de tecido de cordão umbilical humano
CN102387807A (zh) 2008-12-19 2012-03-21 先进科技及再生医学有限责任公司 肺部疾病和病症的治疗
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SG174551A1 (en) * 2009-03-26 2011-10-28 Ethicon Inc Human umbilical cord tissue cells as therapy for alzheimer' s disease
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RU2539750C2 (ru) * 2013-04-09 2015-01-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ оценки иммуносупрессивных свойств мезенхимальных стромальных клеток человека
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HK1256610A1 (zh) * 2015-08-15 2019-09-27 阿斯特利亚斯生物治疗股份公司 用於治疗白质中风的干细胞衍生的少突胶质细胞祖细胞
US10662409B2 (en) 2015-09-09 2020-05-26 Trustees Of Tufts College Methods of generating neural stem cells
JP6967308B1 (ja) * 2020-06-30 2021-11-17 国立大学法人高知大学 胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤
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CN114561355B (zh) * 2022-01-23 2023-04-11 四川大学华西医院 一种脊髓瘢痕组织细胞急性快速分离方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024125295A1 (en) * 2022-12-15 2024-06-20 Center For Excellence In Brain Science And Intelligence Technology, Chinese Academy Of Sciences Striatal neural progenitors in treatment of hypoxic-ischemic encephalopathy
CN118962134A (zh) * 2023-05-15 2024-11-15 上海交通大学医学院附属仁济医院 Ch25h+抑炎型小胶质细胞在缺血性脑卒中治疗中的应用

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CA2747758C (en) 2020-09-22
WO2010071863A1 (en) 2010-06-24
EP2379089A1 (en) 2011-10-26
AU2009327383A1 (en) 2011-08-11
AU2009327383B2 (en) 2014-08-28
EP2379089B1 (en) 2019-04-17
JP2012512910A (ja) 2012-06-07
US20100158880A1 (en) 2010-06-24
JP6095893B2 (ja) 2017-03-15
CA2747758A1 (en) 2010-06-24
BRPI0923070A2 (pt) 2016-06-14

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