|
US5585481A
(en)
*
|
1987-09-21 |
1996-12-17 |
Gen-Probe Incorporated |
Linking reagents for nucleotide probes
|
|
EP0472648A4
(en)
|
1989-05-18 |
1992-09-16 |
Microprobe Corporation |
Crosslinking oligonucleotides
|
|
US5451463A
(en)
*
|
1989-08-28 |
1995-09-19 |
Clontech Laboratories, Inc. |
Non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides
|
|
US5994056A
(en)
*
|
1991-05-02 |
1999-11-30 |
Roche Molecular Systems, Inc. |
Homogeneous methods for nucleic acid amplification and detection
|
|
US5419966A
(en)
*
|
1991-06-10 |
1995-05-30 |
Microprobe Corporation |
Solid support for synthesis of 3'-tailed oligonucleotides
|
|
ATE167525T1
(de)
*
|
1991-07-01 |
1998-07-15 |
Blood Center Of Southeastern W |
Pen-polymorphismus von menschlichem plättchenmembran-glykoprotein-iiia und diagnostische und therapeutische anwendung davon
|
|
US5512677A
(en)
*
|
1991-08-13 |
1996-04-30 |
National Science Council |
3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline derivatives, the preparation and use thereof
|
|
GB9211979D0
(en)
|
1992-06-05 |
1992-07-15 |
Buchard Ole |
Uses of nucleic acid analogues
|
|
US5767259A
(en)
*
|
1994-12-27 |
1998-06-16 |
Naxcor |
Oligonucleotides containing base-free linking groups with photoactivatable side chains
|
|
US5925517A
(en)
*
|
1993-11-12 |
1999-07-20 |
The Public Health Research Institute Of The City Of New York, Inc. |
Detectably labeled dual conformation oligonucleotide probes, assays and kits
|
|
US5538848A
(en)
*
|
1994-11-16 |
1996-07-23 |
Applied Biosystems Division, Perkin-Elmer Corp. |
Method for detecting nucleic acid amplification using self-quenching fluorescence probe
|
|
WO1995030139A1
(en)
*
|
1994-04-29 |
1995-11-09 |
Perkin-Elmer Corporation |
System for real time detection of nucleic acid amplification products
|
|
US5512441A
(en)
*
|
1994-11-15 |
1996-04-30 |
American Health Foundation |
Quantative method for early detection of mutant alleles and diagnostic kits for carrying out the method
|
|
US5801155A
(en)
*
|
1995-04-03 |
1998-09-01 |
Epoch Pharmaceuticals, Inc. |
Covalently linked oligonucleotide minor grove binder conjugates
|
|
US6312894B1
(en)
*
|
1995-04-03 |
2001-11-06 |
Epoch Pharmaceuticals, Inc. |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
|
|
US5736626A
(en)
*
|
1996-01-29 |
1998-04-07 |
The Perkin-Elmer Corporation |
Solid support reagents for the direct synthesis of 3'-labeled polynucleotides
|
|
US6852487B1
(en)
*
|
1996-02-09 |
2005-02-08 |
Cornell Research Foundation, Inc. |
Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
|
|
EP0892808B1
(en)
*
|
1996-04-12 |
2008-05-14 |
PHRI Properties, Inc. |
Detection probes, kits and assays
|
|
EP1736554B1
(en)
*
|
1996-05-29 |
2013-10-09 |
Cornell Research Foundation, Inc. |
Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
|
|
EP1033411B1
(en)
*
|
1996-06-04 |
2006-02-22 |
University of Utah Research Foundation |
Fluorescent donor-acceptor pair
|
|
US5861295A
(en)
*
|
1997-01-02 |
1999-01-19 |
Life Technologies, Inc. |
Nucleic acid-free thermostable enzymes and methods of production thereof
|
|
US6043070A
(en)
|
1997-08-29 |
2000-03-28 |
The Perkin-Elmer Corporation |
Phosphoramidate-phosphodiester oligonucleotide chimera as primers
|
|
ATE478090T1
(de)
*
|
1997-10-27 |
2010-09-15 |
Boston Probes Inc |
SICH AUF ßPNA MOLECULAR BEACONSß BEZIEHENDE VERFAHREN, TESTSÄTZE UND ZUSAMMENSETZUNGEN
|
|
US6485901B1
(en)
|
1997-10-27 |
2002-11-26 |
Boston Probes, Inc. |
Methods, kits and compositions pertaining to linear beacons
|
|
US6303305B1
(en)
*
|
1999-03-30 |
2001-10-16 |
Roche Diagnostics, Gmbh |
Method for quantification of an analyte
|
|
US6383752B1
(en)
*
|
1999-03-31 |
2002-05-07 |
Hybridon, Inc. |
Pseudo-cyclic oligonucleobases
|
|
US6528254B1
(en)
*
|
1999-10-29 |
2003-03-04 |
Stratagene |
Methods for detection of a target nucleic acid sequence
|
|
US6727356B1
(en)
*
|
1999-12-08 |
2004-04-27 |
Epoch Pharmaceuticals, Inc. |
Fluorescent quenching detection reagents and methods
|
|
US6783934B1
(en)
*
|
2000-05-01 |
2004-08-31 |
Cepheid, Inc. |
Methods for quantitative analysis of nucleic acid amplification reaction
|
|
US6605451B1
(en)
*
|
2000-06-06 |
2003-08-12 |
Xtrana, Inc. |
Methods and devices for multiplexing amplification reactions
|
|
US6596490B2
(en)
*
|
2000-07-14 |
2003-07-22 |
Applied Gene Technologies, Inc. |
Nucleic acid hairpin probes and uses thereof
|
|
US20030082549A1
(en)
*
|
2000-08-30 |
2003-05-01 |
Xiangjun Liu |
Method for determining alleles
|
|
US6350580B1
(en)
*
|
2000-10-11 |
2002-02-26 |
Stratagene |
Methods for detection of a target nucleic acid using a probe comprising secondary structure
|
|
US6391592B1
(en)
*
|
2000-12-14 |
2002-05-21 |
Affymetrix, Inc. |
Blocker-aided target amplification of nucleic acids
|
|
DE10112515B4
(de)
*
|
2001-03-09 |
2004-02-12 |
Epigenomics Ag |
Verfahren zum Nachweis von Cytosin-Methylierungsmustern mit hoher Sensitivität
|
|
US6593091B2
(en)
*
|
2001-09-24 |
2003-07-15 |
Beckman Coulter, Inc. |
Oligonucleotide probes for detecting nucleic acids through changes in flourescence resonance energy transfer
|
|
US6589250B2
(en)
*
|
2001-11-20 |
2003-07-08 |
Stephen A. Schendel |
Maxillary distraction device
|
|
US7253007B2
(en)
*
|
2001-11-30 |
2007-08-07 |
Chemocentryx, Inc. |
Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
|
|
BRPI0214741B1
(pt)
|
2001-12-08 |
2015-05-12 |
Seegene Inc |
Iniciador de controle de anelamento para melhorar a especificidade de anelamento na amplificação de ácido nucléico, Kit, Métodos para amplificar seqüências de ácido nucléico de um DNA e seqüência de ácido nucléico alvo ou uma mistura de ácidos nucléicos, para detectar a complementaridade de DNA ao mRNA diferencialmente expresso em duas ou mais amostras de ácido nucléico, para amplificar rapidamente um fragmento de CDNA alvo, para amplificar uma população de CDNAs de filamento duplo de comprimento completo complementar aos mRNAS, e CDNAs de filamento duplo enriquecidos em 5 complementares aos mRNAS, para amplificar mais do que uma seqüência de nucleotídeo alvo simultaneamente, para produzir uma impressão digital de DNA de gDNA, e de RNA de uma amostra de mRNA, para identificar segmentos de homologia conservada em uma família de multigene a partir de uma amostra de mRNA, para identificar uma variação de nucleotídeo em um ácido nucléico alvo, para a mutagênese em um ácido nucléico alvo, e, uso do iniciador
|
|
AU2002222737A1
(en)
|
2001-12-08 |
2003-06-23 |
Seegene, Inc |
Annealing control primer system for regulating primer annealing specificity and its applications
|
|
US7228237B2
(en)
*
|
2002-02-07 |
2007-06-05 |
Applera Corporation |
Automatic threshold setting and baseline determination for real-time PCR
|
|
US6818420B2
(en)
*
|
2002-02-27 |
2004-11-16 |
Biosource International, Inc. |
Methods of using FET labeled oligonucleotides that include a 3′-5′ exonuclease resistant quencher domain and compositions for practicing the same
|
|
US8323897B2
(en)
|
2002-12-04 |
2012-12-04 |
Applied Biosystems, Llc |
Multiplex amplification of polynucleotides
|
|
US7348146B2
(en)
|
2003-10-02 |
2008-03-25 |
Epoch Biosciences, Inc. |
Single nucleotide polymorphism analysis of highly polymorphic target sequences
|
|
AU2005231971A1
(en)
*
|
2004-04-06 |
2005-10-20 |
Epigenomics Ag |
Method for the quantification of methylated DNA
|
|
US7563572B2
(en)
*
|
2004-08-02 |
2009-07-21 |
University Of Utah Research Foundation |
Method for long range allele-specific PCR
|
|
DE102005011398A1
(de)
*
|
2005-03-03 |
2006-09-14 |
Epigenomics Ag |
Verfahren zur Untersuchung von Cytosin-Methylierungen in DNA
|
|
EP2477029A1
(en)
|
2005-06-02 |
2012-07-18 |
Fluidigm Corporation |
Analysis using microfluidic partitioning devices
|
|
US20070087360A1
(en)
*
|
2005-06-20 |
2007-04-19 |
Boyd Victoria L |
Methods and compositions for detecting nucleotides
|
|
WO2007062212A1
(en)
*
|
2005-11-23 |
2007-05-31 |
University Of Southern California |
High throughput method of dna methylation haplotyping
|
|
WO2007106534A2
(en)
*
|
2006-03-14 |
2007-09-20 |
Harbor-Ucla Research And Education Institute |
Selective amplification of minority mutations using primer blocking high-affinity oligonucleotides
|
|
US20080090239A1
(en)
*
|
2006-06-14 |
2008-04-17 |
Daniel Shoemaker |
Rare cell analysis using sample splitting and dna tags
|
|
EP1905842A1
(en)
*
|
2006-09-26 |
2008-04-02 |
DiaSorin S.p.A. |
Method for detection of mutant alleles combining Real Time PCR and REMS-PCR
|
|
GB0703996D0
(en)
|
2007-03-01 |
2007-04-11 |
Oxitec Ltd |
Nucleic acid detection
|
|
US20090053719A1
(en)
*
|
2007-08-03 |
2009-02-26 |
The Chinese University Of Hong Kong |
Analysis of nucleic acids by digital pcr
|
|
US20100041048A1
(en)
|
2008-07-31 |
2010-02-18 |
The Johns Hopkins University |
Circulating Mutant DNA to Assess Tumor Dynamics
|
|
US9534255B2
(en)
|
2008-12-17 |
2017-01-03 |
Life Technologies Corporation |
Methods, compositions, and kits for detecting allelic variants
|
|
EP3249053A1
(en)
|
2009-03-27 |
2017-11-29 |
Life Technologies Corporation |
Methods, compositions, and kits for detecting allelic variants
|
|
WO2011139920A2
(en)
|
2010-04-29 |
2011-11-10 |
Life Technologies Corporation |
Methylation-specific competitive allele-specific taqman polymerase chain reaction (cast-pcr)
|
|
WO2011150075A2
(en)
|
2010-05-25 |
2011-12-01 |
The Johns Hopkins University |
Compositions and methods for detecting a neoplasia
|
|
EP2400035A1
(en)
|
2010-06-28 |
2011-12-28 |
Technische Universität München |
Methods and compositions for diagnosing gastrointestinal stromal tumors
|
|
WO2012097353A1
(en)
|
2011-01-14 |
2012-07-19 |
Life Technologies Corporation |
Methods, compositions, and kits for detecting rare cells
|
|
EP2705162B1
(en)
|
2011-05-04 |
2018-07-11 |
Biocept, Inc. |
Methods for detecting nucleic acid sequence variants
|
|
WO2014004726A1
(en)
|
2012-06-26 |
2014-01-03 |
Caifu Chen |
Methods, compositions and kits for the diagnosis, prognosis and monitoring of cancer
|