JP2012510618A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012510618A5 JP2012510618A5 JP2011538701A JP2011538701A JP2012510618A5 JP 2012510618 A5 JP2012510618 A5 JP 2012510618A5 JP 2011538701 A JP2011538701 A JP 2011538701A JP 2011538701 A JP2011538701 A JP 2011538701A JP 2012510618 A5 JP2012510618 A5 JP 2012510618A5
- Authority
- JP
- Japan
- Prior art keywords
- complement
- hla
- biological sample
- antibody
- agi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000295 complement effect Effects 0.000 claims 40
- 238000000034 method Methods 0.000 claims 25
- 239000012472 biological sample Substances 0.000 claims 17
- 239000000427 antigen Substances 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 239000011859 microparticle Substances 0.000 claims 10
- 239000007787 solid Substances 0.000 claims 10
- 239000000758 substrate Substances 0.000 claims 10
- 210000004027 cell Anatomy 0.000 claims 5
- 239000003446 ligand Substances 0.000 claims 5
- 239000011324 bead Substances 0.000 claims 4
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 238000011534 incubation Methods 0.000 claims 2
- 210000000265 leukocyte Anatomy 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 229920000936 Agarose Polymers 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 239000004793 Polystyrene Substances 0.000 claims 1
- 239000000370 acceptor Substances 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 239000004816 latex Substances 0.000 claims 1
- 229920000126 latex Polymers 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 229920002223 polystyrene Polymers 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11894908P | 2008-12-01 | 2008-12-01 | |
| US61/118,949 | 2008-12-01 | ||
| PCT/US2009/065984 WO2010065425A1 (en) | 2008-12-01 | 2009-11-25 | Methods and compositions for detection of complement fixing antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014183579A Division JP2015007651A (ja) | 2008-12-01 | 2014-09-09 | 補体固定抗体の検出のための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012510618A JP2012510618A (ja) | 2012-05-10 |
| JP2012510618A5 true JP2012510618A5 (https=) | 2013-01-17 |
| JP5792626B2 JP5792626B2 (ja) | 2015-10-14 |
Family
ID=42233567
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011538701A Active JP5792626B2 (ja) | 2008-12-01 | 2009-11-25 | 補体固定抗体の検出のための方法および組成物 |
| JP2014183579A Pending JP2015007651A (ja) | 2008-12-01 | 2014-09-09 | 補体固定抗体の検出のための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014183579A Pending JP2015007651A (ja) | 2008-12-01 | 2014-09-09 | 補体固定抗体の検出のための方法および組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10338080B2 (https=) |
| EP (2) | EP2353005B1 (https=) |
| JP (2) | JP5792626B2 (https=) |
| CN (2) | CN105866426B (https=) |
| AU (1) | AU2009322607B2 (https=) |
| BR (1) | BRPI0923199B8 (https=) |
| CA (1) | CA2740192C (https=) |
| WO (1) | WO2010065425A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3722320A3 (en) | 2012-10-25 | 2020-12-30 | Bioverativ USA Inc. | Anti-complement c1s antibodies and uses thereof |
| DK2914291T3 (da) | 2012-11-02 | 2022-05-16 | Bioverativ Usa Inc | Anti-komplement-c1s-antistoffer og anvendelser deraf |
| WO2014151763A1 (en) * | 2013-03-14 | 2014-09-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting donor-specific antibodies and systems for practicing the same |
| WO2014160376A1 (en) * | 2013-03-14 | 2014-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting complement fixing and non-complement fixing antibodies and systems for practicing the same |
| DK3019240T3 (da) | 2013-07-09 | 2024-06-03 | Annexon Inc | Anti-komplementfaktor C1Q antistoffer og anvendelser deraf |
| SI3215527T1 (sl) * | 2014-11-05 | 2025-04-30 | Annexon, Inc. | Humanizirana protitelesa proti komplementnemu faktorju C1q in njihova uporaba |
| CA2981321A1 (en) | 2015-04-06 | 2016-10-13 | True North Therapeutics, Inc. | Humanized anti-c1s antibodies and methods of use thereof |
| US10527613B2 (en) | 2015-11-10 | 2020-01-07 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarker detection methods and systems and kits for practicing same |
| EP3380518B1 (en) | 2015-11-24 | 2026-03-25 | Annexon, Inc. | Anti-complement factor c1q fab fragments and uses thereof |
| CA3010587C (en) | 2015-12-03 | 2021-08-17 | NJ Sharing Network | Igg subtyping assay for identifying transplantable tissue samples |
| EP3239711B1 (en) | 2016-04-27 | 2019-12-25 | JIMRO Co., Ltd. | Method for measuring anti-drug antibody |
| WO2017187656A1 (ja) * | 2016-04-27 | 2017-11-02 | 株式会社Jimro | 抗医薬品抗体の測定方法 |
| CN110300520B (zh) | 2016-10-12 | 2022-10-04 | 美国比奥维拉迪维股份有限公司 | 抗C1s抗体及其使用方法 |
| US20190383805A1 (en) * | 2017-01-25 | 2019-12-19 | Northeastern University | Electrochemical Antibody-Based Biosensor |
| CN114910635B (zh) * | 2017-10-26 | 2025-05-02 | 科美诊断技术股份有限公司 | 一种无基质效应的均相免疫检测试剂盒及其应用 |
| CN107976535B (zh) * | 2017-11-03 | 2020-03-20 | 科美诊断技术股份有限公司 | 一种检测样本中目标IgM抗体的均相免疫检测试剂盒及其使用方法和应用 |
| CN109991405B (zh) * | 2017-12-29 | 2023-01-24 | 上海索昕生物科技有限公司 | 一种免疫检测试剂盒及其应用 |
| JP7153494B2 (ja) * | 2018-07-27 | 2022-10-14 | シスメックス株式会社 | 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット |
| JP7153493B2 (ja) * | 2018-07-27 | 2022-10-14 | シスメックス株式会社 | 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット |
| DE202020006093U1 (de) * | 2019-05-06 | 2025-04-09 | The Regents Of The University Of California | Nicht-HLA-Marker der Transplantatabstoßung |
| CN111812336A (zh) * | 2020-08-10 | 2020-10-23 | 苏州康和顺医疗技术有限公司 | 用于检测冠状病毒抗体的检测试剂盒及其制备方法 |
| EP4226155A1 (en) * | 2020-10-09 | 2023-08-16 | Takeda Vaccines, Inc. | Methods for determining complement-fixing antibodies |
| US20240142451A1 (en) * | 2021-03-31 | 2024-05-02 | Takeda Vaccines, Inc. | Methods for characterizing the immune response of a subject to a dengue virus composition |
| EP4089413A1 (en) * | 2021-05-12 | 2022-11-16 | Cisbio Bioassays | Method for determining the binding of an antibody to the complement component 1q (c1q) |
| US12486322B2 (en) | 2021-12-13 | 2025-12-02 | Annexon, Inc. | Anti-complement factor C1q antibodies with single binding arms and uses thereof |
| CN118604345A (zh) * | 2024-05-31 | 2024-09-06 | 上海览屹医药科技有限公司 | 酶联免疫方法测定单克隆抗体浓度 |
| CN120142127A (zh) * | 2025-05-16 | 2025-06-13 | 上海荻硕贝肯基因科技有限公司 | 一种供者特异性抗体的检测方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1247080A (en) | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US5035995A (en) * | 1984-10-02 | 1991-07-30 | Calpis Food Industry Co., Ltd. | Test method involving substance-conjugated complement component C1q |
| JPS6184560A (ja) * | 1984-10-02 | 1986-04-30 | Karupisu Shokuhin Kogyo Kk | 補体結合性抗体の測定法 |
| JPS61245060A (ja) | 1985-04-23 | 1986-10-31 | Takara Shuzo Co Ltd | ヒト補体１ｑ定量用キツト及び定量法 |
| JPS6225994A (ja) * | 1985-05-30 | 1987-02-03 | ジエネテイツク システムズ コ−ポレイシヨン | Ｈｌａタイプ分け用モノクロ−ナル抗体 |
| IL84160A0 (en) * | 1986-10-16 | 1988-03-31 | Vasocor | Method and kit for immune complex assay |
| US5176998A (en) | 1986-12-01 | 1993-01-05 | The Scripps Research Institute | Cell surface antigen detection method |
| US5223397A (en) | 1991-06-05 | 1993-06-29 | Sangstat Medical Corporation | Soluble hla cross-match |
| US5270169A (en) * | 1992-06-23 | 1993-12-14 | Sangstat Medical Corporation | Detection of HLA antigen-containing immune complexes |
| AU687010B2 (en) | 1992-07-17 | 1998-02-19 | Dana-Farber Cancer Institute | Method of intracellular binding of target molecules |
| US5851829A (en) | 1993-07-16 | 1998-12-22 | Dana-Farber Cancer Institute | Method of intracellular binding of target molecules |
| GB9502112D0 (en) | 1995-02-03 | 1995-03-22 | British Biocell Int | Assay device and method |
| US6159748A (en) * | 1995-03-13 | 2000-12-12 | Affinitech, Ltd | Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry |
| US5948627A (en) | 1997-05-30 | 1999-09-07 | One Lambda | Immunobead flow cytometric detection of anti-HLA panel-reactive antibody |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| AU759779B2 (en) | 1997-10-31 | 2003-05-01 | Genentech Inc. | Methods and compositions comprising glycoprotein glycoforms |
| CN1423130A (zh) | 2002-04-26 | 2003-06-11 | 帕弗瑞生物技术(北京)有限公司 | 流式测定固定补体抗体的hla交叉配型方法和试剂盒 |
| CN1444044A (zh) | 2002-06-18 | 2003-09-24 | 帕弗瑞生物技术(北京)有限公司 | 以酶联免疫测定为基础的hla补体依赖性细胞毒性抗体检测方法和试剂盒 |
| TW200508609A (en) | 2003-07-15 | 2005-03-01 | Bioarray Solutions Ltd | Detection of cell membrane-associated proteins using membrane fragments displayed on encoded microparticle arrays |
| US20050277158A1 (en) * | 2004-06-10 | 2005-12-15 | Ge Chen | Method and kit for donor specific complement-fixing antibodies crossmatch |
| US7799556B2 (en) * | 2004-06-17 | 2010-09-21 | George Dacai Liu | System and method for antigen structure-independent detection of antigens captured on antibody arrays |
| AU2006244486A1 (en) | 2005-05-06 | 2006-11-16 | Platypus Technologies, Llc | Liquid crystal based analyte detection |
| CN100354629C (zh) * | 2005-10-17 | 2007-12-12 | 中国人民解放军第三军医大学第一附属医院 | 用胶体金标记补体第一成分q亚单位做指示剂的蛋白芯片/微阵列检测系统及检测方法 |
| GB0618496D0 (en) * | 2006-09-20 | 2006-11-01 | Common Services Agency | Blood typing |
| JP2008100986A (ja) * | 2006-09-21 | 2008-05-01 | Takahiro Ochi | Ｃ１ｑ結合物質、ならびにその使用 |
| US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
| JP2009080019A (ja) | 2007-09-26 | 2009-04-16 | Nippon Sekijiyuujishiya | 蛍光ビーズを用いた免疫複合体検出による抗体解析法 |
| DE102008045696A1 (de) | 2008-09-04 | 2010-03-11 | Drk Blutspendedienst West Ggmbh | Granulozyten HNA-3a/b-Antigen |
| CA2763199A1 (en) | 2009-05-29 | 2010-12-02 | The Regents Of The Univeristy Of California | B cell signature associated with tolerance in transplant recipients |
| US20120065092A1 (en) | 2010-09-14 | 2012-03-15 | Wai Hobert | Fusion analyte cytometric bead assay, and systems and kits for performing the same |
| US20140249051A1 (en) | 2011-08-30 | 2014-09-04 | The Governors Of The University Of Alberta | Method and system for abo antibody detection and characterization |
| WO2014151763A1 (en) | 2013-03-14 | 2014-09-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting donor-specific antibodies and systems for practicing the same |
| WO2014160376A1 (en) | 2013-03-14 | 2014-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting complement fixing and non-complement fixing antibodies and systems for practicing the same |
-
2009
- 2009-11-25 CA CA2740192A patent/CA2740192C/en active Active
- 2009-11-25 WO PCT/US2009/065984 patent/WO2010065425A1/en not_active Ceased
- 2009-11-25 CN CN201610218019.2A patent/CN105866426B/zh active Active
- 2009-11-25 EP EP09830911.5A patent/EP2353005B1/en active Active
- 2009-11-25 EP EP18190547.2A patent/EP3460480B1/en active Active
- 2009-11-25 US US13/129,554 patent/US10338080B2/en active Active
- 2009-11-25 AU AU2009322607A patent/AU2009322607B2/en active Active
- 2009-11-25 BR BRPI0923199A patent/BRPI0923199B8/pt not_active IP Right Cessation
- 2009-11-25 JP JP2011538701A patent/JP5792626B2/ja active Active
- 2009-11-25 CN CN2009801446394A patent/CN102203610A/zh active Pending
-
2014
- 2014-09-09 JP JP2014183579A patent/JP2015007651A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012510618A5 (https=) | ||
| Gebel et al. | HLA antibody detection with solid phase assays: great expectations or expectations too great? | |
| Akama et al. | Droplet-free digital enzyme-linked immunosorbent assay based on a tyramide signal amplification system | |
| Ge et al. | Aptamer/antibody sandwich method for digital detection of SARS-CoV2 nucleocapsid protein | |
| Qu et al. | Innovative FO-SPR label-free strategy for detecting anti-RBD antibodies in COVID-19 patient serum and whole blood | |
| CN104245960B (zh) | 用于生物测定的信号放大的方法和系统 | |
| JP2016515215A5 (https=) | ||
| WO2011057347A1 (en) | Analyte detection | |
| JP2009537176A5 (https=) | ||
| Shrock et al. | VirScan: high-throughput profiling of antiviral antibody epitopes | |
| JP2010025745A5 (https=) | ||
| JP2010522875A5 (https=) | ||
| Park et al. | Performance evaluation of new automated hepatitis B viral markers in the clinical laboratory: two quantitative hepatitis B surface antigen assays and an HBV core–related antigen assay | |
| Koo et al. | Amplification‐Free Multi‐RNA‐Type Profiling for Cancer Risk Stratification via Alternating Current Electrohydrodynamic Nanomixing | |
| JP6947780B2 (ja) | 標的物質の検出用試薬、検出方法および標的物質を検出するために用いられる担体ならびにその製造方法 | |
| NO20083080L (no) | Fremgangsmate for a detektere tilstedevaerelse eller fravaer av en malcelle i en prove | |
| Chang et al. | Comparative evaluation and measure of accuracy of ELISAs, CLIAs, and ECLIAs for the detection of HIV infection among blood donors in China | |
| WO2022085790A1 (ja) | 標的物質の検出方法および装置並びに試薬 | |
| JP2011102805A5 (https=) | ||
| Gong et al. | A facile strategy for multiplex protein detection by a fluorescent microsphere-based digital immunoassay | |
| CN102692505A (zh) | 一种改进的免疫共沉淀技术方法 | |
| JP5813111B2 (ja) | イムノアッセイにおける試薬の反応性を制御するためのコカップリング | |
| Singampalli et al. | Highly reusable electrochemical immunosensor for ultrasensitive protein detection | |
| Zhao et al. | Rapid Single‐Cell Proteomics Using Nanoconfined Enzyme Reactors on a Microscale Digital Microfluidics Platform | |
| Smith et al. | Determination of ANA specificity using the UltraPlex™ platform |