JP2016515215A5 - - Google Patents

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JP2016515215A5
JP2016515215A5 JP2016502124A JP2016502124A JP2016515215A5 JP 2016515215 A5 JP2016515215 A5 JP 2016515215A5 JP 2016502124 A JP2016502124 A JP 2016502124A JP 2016502124 A JP2016502124 A JP 2016502124A JP 2016515215 A5 JP2016515215 A5 JP 2016515215A5
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JP
Japan
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hla
antibody
donor
beads
biological sample
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JP2016502124A
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English (en)
Japanese (ja)
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JP2016515215A (ja
JP6548631B2 (ja
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Priority claimed from PCT/US2014/026406 external-priority patent/WO2014151763A1/en
Publication of JP2016515215A publication Critical patent/JP2016515215A/ja
Publication of JP2016515215A5 publication Critical patent/JP2016515215A5/ja
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JP2016502124A 2013-03-14 2014-03-13 ドナー特異的抗体を検出する方法及び該方法を実施するためのシステム Active JP6548631B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361782003P 2013-03-14 2013-03-14
US61/782,003 2013-03-14
PCT/US2014/026406 WO2014151763A1 (en) 2013-03-14 2014-03-13 Methods of detecting donor-specific antibodies and systems for practicing the same

Publications (3)

Publication Number Publication Date
JP2016515215A JP2016515215A (ja) 2016-05-26
JP2016515215A5 true JP2016515215A5 (https=) 2017-04-13
JP6548631B2 JP6548631B2 (ja) 2019-07-24

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JP2016502124A Active JP6548631B2 (ja) 2013-03-14 2014-03-13 ドナー特異的抗体を検出する方法及び該方法を実施するためのシステム

Country Status (8)

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US (3) US10101337B2 (https=)
EP (2) EP3435080A1 (https=)
JP (1) JP6548631B2 (https=)
CN (1) CN105308457B (https=)
AU (1) AU2014236882B2 (https=)
BR (1) BR112015022844B1 (https=)
CA (1) CA2905954C (https=)
WO (1) WO2014151763A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2740192C (en) 2008-12-01 2019-12-31 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for detection of complement fixing antibodies
WO2014151763A1 (en) 2013-03-14 2014-09-25 The Board Of Trustees Of The Leland Stanford Junior University Methods of detecting donor-specific antibodies and systems for practicing the same
US10527613B2 (en) 2015-11-10 2020-01-07 The Board Of Trustees Of The Leland Stanford Junior University Biomarker detection methods and systems and kits for practicing same
JP6994021B2 (ja) * 2016-08-26 2022-01-14 ジュノー セラピューティクス インコーポレイテッド 細胞組成物中に存在する粒子を計数する方法
JP6952295B2 (ja) * 2016-09-09 2021-10-20 国立大学法人金沢大学 ヒト抗hlaモノクローナル抗体の作製方法
EP3571509B1 (en) 2017-01-18 2023-05-10 Sartorius BioAnalytical Instruments, Inc. Methods and reagents for determining immunoglobulin gamma (igg) antibody isotype concentration from biological samples
CN107976535B (zh) * 2017-11-03 2020-03-20 科美诊断技术股份有限公司 一种检测样本中目标IgM抗体的均相免疫检测试剂盒及其使用方法和应用
MA52114A (fr) 2018-02-28 2021-01-06 Juno Therapeutics Inc Procédés de détection de particules présentes dans une composition cellulaire
CN114127560A (zh) * 2019-03-21 2022-03-01 Uab研究基金会 增加细胞对补体介导裂解的敏感性的方法
DE202020006093U1 (de) * 2019-05-06 2025-04-09 The Regents Of The University Of California Nicht-HLA-Marker der Transplantatabstoßung
CN111257566B (zh) * 2020-01-22 2023-03-24 苏州才博医学科技有限公司 用于检测同种异体的、或供者特异性的非hla抗体的方法
CN111413505B (zh) * 2020-04-08 2023-03-24 苏州才博医学科技有限公司 全面检测非hla类供者特异性抗体的细胞学方法
CN112924696A (zh) * 2021-01-27 2021-06-08 浙江大学 一种检测人绒毛滋养细胞外泌体hla-e水平评估母胎免疫耐受的方法
CN114019154A (zh) * 2021-11-09 2022-02-08 河北博因生物科技有限公司 基于流式细胞术用于补体检测的试剂盒及制备方法和应用
CN115125251B (zh) * 2022-08-22 2023-11-03 广东忠信生物科技有限公司 一种高效获得特异性全人单克隆抗体基因的方法和应用

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS501571A (https=) 1973-08-28 1975-01-09
CA1247080A (en) 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US5035995A (en) 1984-10-02 1991-07-30 Calpis Food Industry Co., Ltd. Test method involving substance-conjugated complement component C1q
JPS6184560A (ja) 1984-10-02 1986-04-30 Karupisu Shokuhin Kogyo Kk 補体結合性抗体の測定法
JPS61245060A (ja) 1985-04-23 1986-10-31 Takara Shuzo Co Ltd ヒト補体1q定量用キツト及び定量法
JPS6225994A (ja) 1985-05-30 1987-02-03 ジエネテイツク システムズ コ−ポレイシヨン Hlaタイプ分け用モノクロ−ナル抗体
IL84160A0 (en) 1986-10-16 1988-03-31 Vasocor Method and kit for immune complex assay
US5176998A (en) 1986-12-01 1993-01-05 The Scripps Research Institute Cell surface antigen detection method
US5504337A (en) 1990-10-10 1996-04-02 Joseph R. Lakowicz Method and apparatus for performing phase fluorescence lifetime measurements in flow cytometry
US5223397A (en) 1991-06-05 1993-06-29 Sangstat Medical Corporation Soluble hla cross-match
US5270169A (en) 1992-06-23 1993-12-14 Sangstat Medical Corporation Detection of HLA antigen-containing immune complexes
AU687010B2 (en) 1992-07-17 1998-02-19 Dana-Farber Cancer Institute Method of intracellular binding of target molecules
US5851829A (en) 1993-07-16 1998-12-22 Dana-Farber Cancer Institute Method of intracellular binding of target molecules
GB9502112D0 (en) 1995-02-03 1995-03-22 British Biocell Int Assay device and method
US6159748A (en) 1995-03-13 2000-12-12 Affinitech, Ltd Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry
US5948627A (en) 1997-05-30 1999-09-07 One Lambda Immunobead flow cytometric detection of anti-HLA panel-reactive antibody
NZ516848A (en) 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
AU759779B2 (en) 1997-10-31 2003-05-01 Genentech Inc. Methods and compositions comprising glycoprotein glycoforms
US6682940B2 (en) 1999-05-04 2004-01-27 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
WO2003020904A2 (en) 2001-08-31 2003-03-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods of generating human cd4+ th1 cells
CN1423130A (zh) 2002-04-26 2003-06-11 帕弗瑞生物技术(北京)有限公司 流式测定固定补体抗体的hla交叉配型方法和试剂盒
CN1444044A (zh) 2002-06-18 2003-09-24 帕弗瑞生物技术(北京)有限公司 以酶联免疫测定为基础的hla补体依赖性细胞毒性抗体检测方法和试剂盒
TW200508609A (en) * 2003-07-15 2005-03-01 Bioarray Solutions Ltd Detection of cell membrane-associated proteins using membrane fragments displayed on encoded microparticle arrays
US20050277158A1 (en) 2004-06-10 2005-12-15 Ge Chen Method and kit for donor specific complement-fixing antibodies crossmatch
US7799556B2 (en) 2004-06-17 2010-09-21 George Dacai Liu System and method for antigen structure-independent detection of antigens captured on antibody arrays
AU2006244486A1 (en) 2005-05-06 2006-11-16 Platypus Technologies, Llc Liquid crystal based analyte detection
CN100354629C (zh) 2005-10-17 2007-12-12 中国人民解放军第三军医大学第一附属医院 用胶体金标记补体第一成分q亚单位做指示剂的蛋白芯片/微阵列检测系统及检测方法
WO2008060713A2 (en) 2006-06-22 2008-05-22 Massachusetts Institute Of Technology Flow cytometry methods and immunodiagnostics with mass sensitive readout
GB0618496D0 (en) 2006-09-20 2006-11-01 Common Services Agency Blood typing
JP2008100986A (ja) 2006-09-21 2008-05-01 Takahiro Ochi C1q結合物質、ならびにその使用
US20090075378A1 (en) 2007-02-20 2009-03-19 Anaptysbio, Inc. Somatic hypermutation systems
US7964350B1 (en) * 2007-05-18 2011-06-21 Applied Biosystems, Llc Sample preparation for in situ nucleic acid analysis
JP2009080019A (ja) 2007-09-26 2009-04-16 Nippon Sekijiyuujishiya 蛍光ビーズを用いた免疫複合体検出による抗体解析法
DE102008045696A1 (de) * 2008-09-04 2010-03-11 Drk Blutspendedienst West Ggmbh Granulozyten HNA-3a/b-Antigen
CA2740192C (en) * 2008-12-01 2019-12-31 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for detection of complement fixing antibodies
CA2763199A1 (en) * 2009-05-29 2010-12-02 The Regents Of The Univeristy Of California B cell signature associated with tolerance in transplant recipients
US9637719B2 (en) 2013-12-06 2017-05-02 Douglas T. Gjerde Devices and methods for purification of biological cells
US20120065092A1 (en) 2010-09-14 2012-03-15 Wai Hobert Fusion analyte cytometric bead assay, and systems and kits for performing the same
US20140249051A1 (en) 2011-08-30 2014-09-04 The Governors Of The University Of Alberta Method and system for abo antibody detection and characterization
WO2014160376A1 (en) 2013-03-14 2014-10-02 The Board Of Trustees Of The Leland Stanford Junior University Methods of detecting complement fixing and non-complement fixing antibodies and systems for practicing the same
WO2014151763A1 (en) * 2013-03-14 2014-09-25 The Board Of Trustees Of The Leland Stanford Junior University Methods of detecting donor-specific antibodies and systems for practicing the same
SG10201708048XA (en) 2013-03-18 2017-10-30 Biocerox Prod Bv Humanized anti-cd134 (ox40) antibodies and uses thereof
CA2949537C (en) 2014-05-23 2023-02-14 Firefly Bioworks, Inc. Substrate-mediated reactors for bioassays
MA41414A (fr) 2015-01-28 2017-12-05 Centre Nat Rech Scient Protéines de liaison agonistes d' icos
US11116795B2 (en) 2015-07-10 2021-09-14 The Trustees Of The University Of Pennsylvania Treatment of a canine CD20 positive disease or condition using a canine CD20-specific chimeric antigen receptor
US10527613B2 (en) 2015-11-10 2020-01-07 The Board Of Trustees Of The Leland Stanford Junior University Biomarker detection methods and systems and kits for practicing same

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