JP2012510431A5 - - Google Patents
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- JP2012510431A5 JP2012510431A5 JP2011537796A JP2011537796A JP2012510431A5 JP 2012510431 A5 JP2012510431 A5 JP 2012510431A5 JP 2011537796 A JP2011537796 A JP 2011537796A JP 2011537796 A JP2011537796 A JP 2011537796A JP 2012510431 A5 JP2012510431 A5 JP 2012510431A5
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- JP
- Japan
- Prior art keywords
- peptide
- composition
- seq
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 45
- 239000012634 fragment Substances 0.000 claims 17
- 125000003275 alpha amino acid group Chemical group 0.000 claims 15
- 102000040430 polynucleotide Human genes 0.000 claims 14
- 108091033319 polynucleotide Proteins 0.000 claims 14
- 239000002157 polynucleotide Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- 229960005486 vaccine Drugs 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 12
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 8
- 208000015943 Coeliac disease Diseases 0.000 claims 6
- 108010068370 Glutens Proteins 0.000 claims 6
- 235000021312 gluten Nutrition 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 230000028327 secretion Effects 0.000 claims 4
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical group OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 claims 3
- 210000001744 T-lymphocyte Anatomy 0.000 claims 3
- 239000002671 adjuvant Substances 0.000 claims 3
- 210000004899 c-terminal region Anatomy 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 102000003814 Interleukin-10 Human genes 0.000 claims 2
- 108090000174 Interleukin-10 Proteins 0.000 claims 2
- 102000000588 Interleukin-2 Human genes 0.000 claims 2
- 108010002350 Interleukin-2 Proteins 0.000 claims 2
- 108091005804 Peptidases Proteins 0.000 claims 2
- 239000004365 Protease Substances 0.000 claims 2
- ODHCTXKNWHHXJC-GSVOUGTGSA-N Pyroglutamic acid Chemical group OC(=O)[C@H]1CCC(=O)N1 ODHCTXKNWHHXJC-GSVOUGTGSA-N 0.000 claims 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 2
- 230000005867 T cell response Effects 0.000 claims 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 2
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 2
- ODHCTXKNWHHXJC-UHFFFAOYSA-N acide pyroglutamique Chemical group OC(=O)C1CCC(=O)N1 ODHCTXKNWHHXJC-UHFFFAOYSA-N 0.000 claims 2
- 125000003368 amide group Chemical group 0.000 claims 2
- 230000030741 antigen processing and presentation Effects 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- 230000006058 immune tolerance Effects 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 229940076144 interleukin-10 Drugs 0.000 claims 2
- 230000002797 proteolythic effect Effects 0.000 claims 2
- 102000008070 Interferon-gamma Human genes 0.000 claims 1
- 108010074328 Interferon-gamma Proteins 0.000 claims 1
- 150000001408 amides Chemical group 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 238000003776 cleavage reaction Methods 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000002889 endothelial cell Anatomy 0.000 claims 1
- 230000002440 hepatic effect Effects 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 229960003130 interferon gamma Drugs 0.000 claims 1
- 210000002540 macrophage Anatomy 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 230000007017 scission Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11864308P | 2008-11-30 | 2008-11-30 | |
| US61/118,643 | 2008-11-30 | ||
| PCT/AU2009/001556 WO2010060155A1 (en) | 2008-11-30 | 2009-11-30 | Compositions and methods for treatment of celiac disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015235197A Division JP6027215B2 (ja) | 2008-11-30 | 2015-12-01 | セリアック病の処置のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012510431A JP2012510431A (ja) | 2012-05-10 |
| JP2012510431A5 true JP2012510431A5 (cg-RX-API-DMAC7.html) | 2013-03-28 |
| JP5851243B2 JP5851243B2 (ja) | 2016-02-03 |
Family
ID=42225141
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537796A Expired - Fee Related JP5851243B2 (ja) | 2008-11-30 | 2009-11-30 | セリアック病の処置のための組成物および方法 |
| JP2015235197A Expired - Fee Related JP6027215B2 (ja) | 2008-11-30 | 2015-12-01 | セリアック病の処置のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015235197A Expired - Fee Related JP6027215B2 (ja) | 2008-11-30 | 2015-12-01 | セリアック病の処置のための組成物および方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US8835603B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2367561B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5851243B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN105079781B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009321481B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0922122A2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA3042826A1 (cg-RX-API-DMAC7.html) |
| DK (2) | DK2367561T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2642096T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1249446A1 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20150873T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE027237T2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX346450B (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ593474A (cg-RX-API-DMAC7.html) |
| PT (1) | PT2367561E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010060155A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (53)
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| US10105437B2 (en) * | 2004-04-28 | 2018-10-23 | Btg International Limited | Epitopes related to coeliac disease |
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| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9518087B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| CN103430025B (zh) * | 2011-01-20 | 2017-12-26 | 西瑞斯实验室有限公司 | 检测谷蛋白敏感性和其区分于乳糜泻的方法和装置 |
| ITRM20110487A1 (it) * | 2011-09-19 | 2013-03-20 | Consiglio Per La Ricerca E La Speri Mentazione In | Peptidi aventi effetto protettivo nei confronti della attività infiammatoria del peptide 31-43 della a-gliadina nella malattia celiaca. |
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| EP3638296A1 (en) | 2017-06-16 | 2020-04-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| JP2020534352A (ja) | 2017-09-07 | 2020-11-26 | キュー バイオファーマ，インコーポレーテッド | コンジュゲーション部位を有するｔ細胞調節多量体ポリペプチド及びその使用方法 |
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| CN106117330B (zh) | 2011-12-05 | 2019-12-06 | 伯乐实验室公司 | 重组脱酰胺化麦醇溶蛋白抗原 |
| AU2014240046A1 (en) | 2013-03-14 | 2015-10-08 | Robert P. Anderson | Placebo-controlled gluten challenge method |
| EP3043812A1 (en) | 2013-09-10 | 2016-07-20 | Immusant Inc. | Dosage of a gluten peptide composition |
| AU2013400677A1 (en) | 2013-09-20 | 2016-05-12 | Immusant, Inc. | Compositions and methods related to oat sensitivity |
| WO2015164747A1 (en) | 2014-04-24 | 2015-10-29 | Immusant, Inc. | Methods for diagnosing celiac disease using circulating cytokines/chemokines |
-
2009
- 2009-11-30 MX MX2011005632A patent/MX346450B/es active IP Right Grant
- 2009-11-30 CA CA3042826A patent/CA3042826A1/en not_active Abandoned
- 2009-11-30 DK DK09828453.2T patent/DK2367561T3/en active
- 2009-11-30 HU HUE09828453A patent/HUE027237T2/en unknown
- 2009-11-30 WO PCT/AU2009/001556 patent/WO2010060155A1/en not_active Ceased
- 2009-11-30 PT PT98284532T patent/PT2367561E/pt unknown
- 2009-11-30 NZ NZ593474A patent/NZ593474A/xx not_active IP Right Cessation
- 2009-11-30 CN CN201510292861.6A patent/CN105079781B/zh not_active Expired - Fee Related
- 2009-11-30 DK DK15168279.6T patent/DK2977053T3/en active
- 2009-11-30 EP EP20090828453 patent/EP2367561B1/en not_active Not-in-force
- 2009-11-30 EP EP17175226.4A patent/EP3269379A1/en not_active Withdrawn
- 2009-11-30 EP EP15168279.6A patent/EP2977053B1/en not_active Not-in-force
- 2009-11-30 CA CA2744787A patent/CA2744787C/en active Active
- 2009-11-30 HR HRP20150873TT patent/HRP20150873T1/hr unknown
- 2009-11-30 CN CN200980155615.9A patent/CN102438643B/zh not_active Expired - Fee Related
- 2009-11-30 AU AU2009321481A patent/AU2009321481B2/en not_active Ceased
- 2009-11-30 US US13/131,787 patent/US8835603B2/en active Active
- 2009-11-30 BR BRPI0922122A patent/BRPI0922122A2/pt not_active IP Right Cessation
- 2009-11-30 ES ES15168279.6T patent/ES2642096T3/es active Active
- 2009-11-30 ES ES09828453.2T patent/ES2549481T3/es active Active
- 2009-11-30 JP JP2011537796A patent/JP5851243B2/ja not_active Expired - Fee Related
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2014
- 2014-08-13 US US14/459,060 patent/US9464120B2/en not_active Expired - Fee Related
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2015
- 2015-12-01 JP JP2015235197A patent/JP6027215B2/ja not_active Expired - Fee Related
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2016
- 2016-09-09 US US15/260,990 patent/US20170158743A1/en not_active Abandoned
-
2018
- 2018-06-18 US US16/010,596 patent/US20190048047A1/en not_active Abandoned
- 2018-07-16 HK HK18109154.3A patent/HK1249446A1/en unknown
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2020
- 2020-05-27 US US16/884,533 patent/US20210115096A1/en not_active Abandoned
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