JP2012509351A5 - - Google Patents
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- Publication number
- JP2012509351A5 JP2012509351A5 JP2011537657A JP2011537657A JP2012509351A5 JP 2012509351 A5 JP2012509351 A5 JP 2012509351A5 JP 2011537657 A JP2011537657 A JP 2011537657A JP 2011537657 A JP2011537657 A JP 2011537657A JP 2012509351 A5 JP2012509351 A5 JP 2012509351A5
- Authority
- JP
- Japan
- Prior art keywords
- silver
- item
- organic compound
- compound
- substituent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11634508P | 2008-11-20 | 2008-11-20 | |
| US61/116,345 | 2008-11-20 | ||
| US14344109P | 2009-01-09 | 2009-01-09 | |
| US61/143,441 | 2009-01-09 | ||
| US16701809P | 2009-04-06 | 2009-04-06 | |
| US61/167,018 | 2009-04-06 | ||
| US17790709P | 2009-05-13 | 2009-05-13 | |
| US61/177,907 | 2009-05-13 | ||
| PCT/US2009/065339 WO2010059943A2 (en) | 2008-11-20 | 2009-11-20 | Fluorination of organic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012509351A JP2012509351A (ja) | 2012-04-19 |
| JP2012509351A5 true JP2012509351A5 (https=) | 2013-01-17 |
Family
ID=42198823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537657A Pending JP2012509351A (ja) | 2008-11-20 | 2009-11-20 | 有機化合物のフッ素化 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9024093B2 (https=) |
| EP (1) | EP2376408A4 (https=) |
| JP (1) | JP2012509351A (https=) |
| KR (1) | KR20110095898A (https=) |
| CN (1) | CN102272077A (https=) |
| AU (1) | AU2009316478A1 (https=) |
| CA (1) | CA2742869A1 (https=) |
| WO (1) | WO2010059943A2 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009149347A1 (en) * | 2008-06-05 | 2009-12-10 | President And Fellows Of Harvard College | High-valent palladium fluoride complexes and uses thereof |
| AU2009316478A1 (en) | 2008-11-20 | 2010-05-27 | President And Fellows Of Harvard College | Fluorination of organic compounds |
| GB201117019D0 (en) | 2011-10-04 | 2011-11-16 | Syngenta Ltd | Herbicidal compounds |
| WO2012054782A2 (en) * | 2010-10-20 | 2012-04-26 | Presidents And Fellows Of Harvard College | Fluoroalkoxylation of organic compounds |
| WO2012142162A2 (en) | 2011-04-12 | 2012-10-18 | President And Fellows Of Harvard College | Fluorination of organic compounds |
| US20120309796A1 (en) | 2011-06-06 | 2012-12-06 | Fariborz Firooznia | Benzocycloheptene acetic acids |
| CN102675329B (zh) * | 2012-06-05 | 2014-12-24 | 浙江大学 | 一种正电子发射断层显像剂及其制备方法 |
| CN102675015B (zh) * | 2012-06-11 | 2014-11-05 | 中国科学院上海有机化学研究所 | 羧酸脱羧氟代的方法 |
| US9273083B2 (en) | 2012-09-26 | 2016-03-01 | President And Fellows Of Harvard College | Nickel fluorinating complexes and uses thereof |
| US20150336926A1 (en) * | 2013-01-01 | 2015-11-26 | The Regents Of The University Of California | Fluorination of aryl compounds |
| WO2015058047A2 (en) | 2013-10-18 | 2015-04-23 | President And Fellows Of Harvard College | Fluorination of organic compounds |
| EP2891657A1 (en) | 2014-01-07 | 2015-07-08 | Centre National de la Recherche Scientifique (CNRS) | Ionic liquid supported organotin reagents for the manufacturing of radiopharmaceuticals compounds |
| WO2017031050A1 (en) * | 2015-08-14 | 2017-02-23 | Massachusetts Institute Of Technology | Molecularly tunable heterogeneous catalysts by edge functionalization of graphitic carbons |
| CN105646119B (zh) * | 2016-01-29 | 2018-03-13 | 中南大学 | 一种肉桂酸及其衍生物脱羧上氟的方法 |
| EP3527570A4 (en) | 2016-10-14 | 2020-04-15 | Jiangsu Hengrui Medicine Co., Ltd. | FIVE-LINKED HETERARYARYLE CYCLE BRIDGE DERIVATIVE, METHOD FOR PREPARING SAME, AND MEDICAL USE THEREOF |
| FI3634975T3 (fi) | 2017-06-08 | 2024-05-03 | Organon R&D Finland Ltd | 15-beeta-[3-propanamido]substituoitujen estra-1,3,5(10)-trien-17-onien 17-oksiimeja käytettäväksi 17-beeta-hydroksisteroididehydrogenaasien inhiboimisessa |
| EP3438077A1 (en) * | 2017-07-31 | 2019-02-06 | Studiengesellschaft Kohle mbH | Process for deoxyfluorination of phenols |
| CN108863834B (zh) * | 2018-08-13 | 2020-12-15 | 信阳师范学院 | 一种2-氟代-1,3-二羰基化合物的合成新方法 |
| BR112021010598A2 (pt) | 2018-12-05 | 2021-08-24 | Forendo Pharma Ltd | Compostos, método para preparação de um composto e composição farmacêutica |
| US20230295082A1 (en) * | 2020-08-04 | 2023-09-21 | University Of South Africa | Modified ezetimibe drug for cancer treatment |
| CN112710757B (zh) * | 2020-12-23 | 2022-05-17 | 九江天赐高新材料有限公司 | N-苯基双(三氟甲磺酰亚胺)的检测方法 |
| CN114716910B (zh) * | 2022-03-30 | 2022-12-27 | 浙江鑫钰新材料有限公司 | 一种合成革用有机硅耐刮擦防污涂层及其制备方法 |
| CN114805017B (zh) * | 2022-04-29 | 2023-10-10 | 上海毕得医药科技股份有限公司 | 一种2-氟-1,5-己二烯类化合物的制备方法 |
| JP2026509230A (ja) * | 2023-03-07 | 2026-03-17 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ | 多発性硬化症（ｍｓ）及び他の脱髄性、炎症性及び神経変性疾患の予防及び治療のためのホウ素置換インダゾール |
| US11999755B1 (en) | 2024-01-05 | 2024-06-04 | King Faisal University | Effective anticancer drug candidate of dinuclear palladium (II) bis-dihydrozone malonyl complex |
| JP2026023580A (ja) * | 2024-08-01 | 2026-02-13 | ダイキン工業株式会社 | フッ素化有機化合物の製造方法 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3137701A (en) | 1962-04-19 | 1964-06-16 | Upjohn Co | Process for the preparation of 6-deoxy-6-fluoromorphines, 6-deoxy-6-fluorocodeines, and related compounds |
| GB1177525A (en) | 1967-04-13 | 1970-01-14 | Leo Ab | New Heterocyclic Aminoketones of Therapeutic Interest |
| CH540221A (de) | 1968-03-20 | 1973-08-15 | Hoffmann La Roche | Verfahren zur Herstellung von tricyclischen Verbindungen |
| GB1483343A (en) | 1973-10-22 | 1977-08-17 | Res Inst Medicine Chem | Derivatives of amitriptyline and pharmaceutical uses thereof |
| US3972936A (en) | 1974-02-01 | 1976-08-03 | Merck & Co., Inc. | 10,11-Dihydro-5-(3-amino-propyl-or-propylidene)-10,10,11,11-tetra-fluoro-5H-dibenzo[a,d]cycloheptenes and-5-ols |
| US4236008A (en) | 1978-09-19 | 1980-11-25 | E. I. Du Pont De Nemours And Company | Fluorination of precursors for fluorine analogs of hydrocodone and oxycodone |
| IT1147349B (it) | 1980-04-09 | 1986-11-19 | Acraf | 2-parentesi quadra aperta 3-parentesi quadra aperta 4-(3-cloro-4-fluorofenil)-1-piperfrazinil parentesi quadra propil parentesi quadra chiusa-1,2,4-triazolo parentesi quadra aperta 4,3 parentesi quadra chiusa piridin-3(2h)-one |
| US4487773A (en) | 1981-03-16 | 1984-12-11 | Mead Johnson & Company | 1,2,4-Triazol-3-one antidepressants |
| JPS63166159A (ja) | 1986-12-26 | 1988-07-09 | Mitsubishi Heavy Ind Ltd | 固体電解質燃料電池 |
| DE19548146C1 (de) | 1995-12-21 | 1997-11-20 | Basf Ag | Tris(pyrazolyl)boratmetallkomplex-Katalysatoren und deren Verwendung |
| US6187782B1 (en) | 1997-03-27 | 2001-02-13 | Toray Industries, Inc. | Morphinane derivatives and medicinal use thereof |
| IL129219A0 (en) | 1998-04-07 | 2000-02-17 | Mitsui Chemicals Inc | Preparation process of acetylene derivatives |
| JP2003507354A (ja) | 1999-08-11 | 2003-02-25 | ユニべルシテ・カトリック・ドゥ・ルベン | 細胞の低酸素症を検出するためのパーフルオロ化〔１８ｆ〕放射性同位体標識ニトロイミダゾール誘導体の製法 |
| GB0115929D0 (en) | 2001-06-29 | 2001-08-22 | Nycomed Amersham Plc | Solid-phase electrophilic fluorination |
| WO2003020732A2 (en) | 2001-07-24 | 2003-03-13 | Alamx, L.L.C. | 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors. |
| GB0229686D0 (en) | 2002-12-20 | 2003-01-29 | Amersham Plc | Solid-phase fluorination of benzothiazoles |
| DE10300112A1 (de) | 2003-01-07 | 2004-07-15 | Bayer Ag | Fluorierungsreagenzien und Verfahren zu deren Herstellung |
| US8101199B2 (en) * | 2003-10-21 | 2012-01-24 | Celonova Biosciences, Inc. | Des-methyl-tocopherol therapy for restenosis prevention |
| US7022872B2 (en) | 2003-12-19 | 2006-04-04 | Molecular Technologies, Inc. | Method for making fluorine labeled L-Dopa |
| SG133606A1 (en) | 2003-12-22 | 2007-07-30 | Acadia Pharm Inc | Amino substituted diaryl [a,d] cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| GB0407952D0 (en) | 2004-04-08 | 2004-05-12 | Amersham Plc | Fluoridation method |
| US20050282859A1 (en) | 2004-06-04 | 2005-12-22 | Thor Karl B | Dual acting SNRI-NMDA antagonists for the treatment of genitourinary disorders |
| AR051596A1 (es) | 2004-10-26 | 2007-01-24 | Irm Llc | Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios |
| WO2006078752A2 (en) * | 2005-01-21 | 2006-07-27 | Methylgene, Inc. | Inhibitors of dna methyltransferase |
| WO2008081477A1 (en) | 2007-01-04 | 2008-07-10 | Natco Pharma Limited | 3-aryloxy 3-substituted propanamines |
| US8722726B2 (en) | 2007-01-25 | 2014-05-13 | Allergan, Inc. | Substituted arylcyclopentenes as therapeutic agents |
| WO2009046848A1 (en) | 2007-09-11 | 2009-04-16 | Mondobiotech Laboratories Ag | Use of the peptide thymosin beta 4 alone or in combination with cecropin a as a therapeutic agent |
| WO2009100014A1 (en) | 2008-01-31 | 2009-08-13 | President And Fellows Of Harvard College | System for fluorinating organic compounds |
| DE102008024221A1 (de) | 2008-05-19 | 2009-11-26 | Merck Patent Gmbh | Herstellung von CF3O-Gruppen enthaltenden Verbindungen |
| WO2009149347A1 (en) | 2008-06-05 | 2009-12-10 | President And Fellows Of Harvard College | High-valent palladium fluoride complexes and uses thereof |
| AU2009316478A1 (en) | 2008-11-20 | 2010-05-27 | President And Fellows Of Harvard College | Fluorination of organic compounds |
| EP2385944A4 (en) | 2009-01-09 | 2013-06-19 | Harvard College | FLUORINARY COMPOUNDS AND METHOD OF USE THEREOF |
| WO2010081034A2 (en) | 2009-01-09 | 2010-07-15 | President And Fellows Of Harvard College | Fluorine containing compounds and methods of use thereof |
| WO2011006088A2 (en) | 2009-07-09 | 2011-01-13 | President And Fellows Of Harvard College | Fluorine containing compounds and methods of use thereof |
| US20140018538A1 (en) | 2010-08-20 | 2014-01-16 | President And Fellows Of Harvard College | High-valent palladium fluoride complexes and uses thereof |
| WO2012054782A2 (en) | 2010-10-20 | 2012-04-26 | Presidents And Fellows Of Harvard College | Fluoroalkoxylation of organic compounds |
| WO2012142162A2 (en) | 2011-04-12 | 2012-10-18 | President And Fellows Of Harvard College | Fluorination of organic compounds |
-
2009
- 2009-11-20 AU AU2009316478A patent/AU2009316478A1/en not_active Abandoned
- 2009-11-20 US US13/130,033 patent/US9024093B2/en active Active
- 2009-11-20 KR KR1020117013998A patent/KR20110095898A/ko not_active Withdrawn
- 2009-11-20 CA CA2742869A patent/CA2742869A1/en not_active Abandoned
- 2009-11-20 JP JP2011537657A patent/JP2012509351A/ja active Pending
- 2009-11-20 WO PCT/US2009/065339 patent/WO2010059943A2/en not_active Ceased
- 2009-11-20 CN CN2009801533072A patent/CN102272077A/zh active Pending
- 2009-11-20 EP EP09828291A patent/EP2376408A4/en not_active Withdrawn
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